95229799480>Cervicovaginal <n>foetal fibronectin</n> in the prediction of preterm labour in a low-risk population .
98823379047><n>Varicella-zoster virus ( VZV ) glycoprotein gI</n> is a <n>type 1 transmembrane glycoprotein</n> which is one component of the heterodimeric <n>gE</n> : <n>gI Fc receptor</n> complex .
81395429709>A segment of mRNA encoding the leader peptide of the <n>CPA1 gene</n> confers repression by arginine on a heterologous yeast gene transcript .
83032338277>In addition , lexical priming was examined by presenting an identity prime earlier in the text .
40346664700>Lower extremity weight bearing under various standing conditions in independently ambulatory patients with hemiparesis .
19306602252><n>Insulin-like growth factor 1</n> ( <n>IGF-1</n> ) in burn patients .
36106634277>This approach enables the sources of error in the calculation of nutrient utilization to be readily identified , and their effect on precision to be assessed in different nutritional and metabolic states .
16485301583>We identify the "M region" of the <n>muscle-specific Xenopus cardiac actin gene promoter</n> from -282 to -348 as necessary for the embryonic expression of a <n>cardiac actin-beta-globin reporter gene</n> injected into fertilized eggs .
86494253785>We found that 120 bp of the enhancer's transcriptional core becomes <n>DNase I</n> hypersensitive early in B-cell development .
114288973936>Biochemical experiments have shown that <n>CopG</n> co-operatively associates to its target DNA at low protein : DNA ratios , completely protecting four helical turns on the same face of the double helix in both directions from the inverted repeat that constitutes the <n>CopG</n> primary target .
55701755604>3 .
85316693973>Competition needs to be better studied , since in Central America and Caribean islands this kind of study has favored the biological control of planorbid species .
75467947420>Echocardiography revealed right ventricular diastolic collapse ( RVDC ) without physical signs of cardiac tamponade .
13393732909>Structure and expression of a gene from Arabidopsis thaliana encoding a protein related to <n>SNF1 protein</n>1 <n>kinase</n>1 .
92686611279>Our results indicate that the retroplasmid <n>reverse transcriptase</n> is uniquely adapted to initiate cDNA synthesis by recognizing a 3' CCA sequence .
93937719453><n>TNF-alpha</n> exposure markedly increased activity of several RNA-binding proteins , especially a novel Mr 50 , 000-55 , 000 RNA-binding protein .
110312525757>The <n>LMW FGF-2</n> up-regulated the <n>PKC epsilon</n> levels by 1 . 6-fold ; by contrast the <n>HMW isoform</n> down-regulated the level of this <n>PKC isotype</n> by about 3-fold and increased the amount of <n>PKC delta</n> by 1 . 7-fold .
118978881805>Urine samples collected after the administration of these supplements can test positive .
68825786682>In the ultramarathon runner the testosterone levels sharply rose at the beginning of the training session ( from the 7 , 20 ng / ml to 11 , 50 ng / ml after 20' training ) , and subsequently decrease after 3 hours ( 9 , 20 ng / ml ) and at the end of the 6 hours training ( 4 , 60 ng / ml ) .
12813221925>A significant direct relationship was observed between the percent area density of smooth muscle and the percent change in peak urinary flow rate .
46158282294>60th birthday of colonel prof . e . cerny m . d .
296514990>In a previous study ( Brandl , C .
106080531664>Thrombolysis was followed by a similar increase of platelet activity with maximal values reached at the 3rd hour in both groups ( 196 + / - 43 IU / ml in Group 1 and 192 + / - 39 in Group 2 : p < 001versus baseline and p NS between the groups ) .
35534398015>The latter was determined as follows : Type I-solid tumor tissue without significant peripheral isolated tumor cells ; Type II-solid tumor tissue associated with peripheral isolated tumor cells ; Type III-isolated tumor cells only .
1717925275>Comparison of the nucleotide sequences between the human and bovine DNA showed that the sequence similarity extended 2400 bp downstream from the coding region .
50453515334>Periodic breathing and apnea in preterm infants .
47942185819>Antivitamin K agents .
14837712101>Simultaneously a greater NA was found with no change in plasma epinephrine response .
92251519177>The behavior of different types of polytetrafluoroethylene ( PTFE ) prostheses in the reparative scarring process of abdominal wall defects .
53591305491>IX .
18377874942>The <n>murine Mov-34 gene</n> : full-length cDNA and genomic organization .
76996324548>Among the mixed race persons one Chukcha-Eskimo had AS , one Eskimo-Russian had psoriatic arthritis ( PsA ) .
93352987825>To examine the basis for the apparent differences in postsegregational killing between the two E . coli strains , transformation assays were carried out to determine the relative sensitivities of the strains to the <n>ParE toxin protein</n> .
93681007690>The <n>mHIF-1 alpha structural gene</n> is composed of 15 exons .
1296591935>Variability within Down's syndrome ( trisomy-21 ) : empirically observed sex differences in IQs .
81921407630>The participants were homosexual men in hepatitis B vaccine trials in Amsterdam ( n = 74 ) , New York City ( n = 120 ) , and San Francisco ( n = 168 ) .
20650222271>Very small deletions within the conserved region completely abolished transforming activity of <n>dbl</n> , while extensive deletion outside of this region had no effect .
42622684890>Studies on the organic matrix of human ear ossicles .
5097035372>These differences are smaller than those described in standard textbooks .
100905354526>The algorithm also limited TG to 20 and 64% , <n>apoB</n> to 6 and 20% , and <n>Lp ( a )</n> to 15 and 56% , of low- and high-risk groups , respectively .
21234669976>Like other members of this family , the <n>AP-4 HLH</n>1 <n>motif</n>1 and the adjacent basic domain are necessary and sufficient to confer site-specific DNA binding .
26660348492>Following the patients during a course of therapy with a selective vasodilator calcium antagonist , the beta-adrenergic reflex vasodilation became substantially attenuated but was preserved during a placebo course of therapy .
96220554152>Two members of the <n>Cbl family</n> have since been defined in mammals ( <n>c-Cbl</n> and <n>Cbl-b</n> ) , one in C . elegans ( <n>Sli-1</n> ) and one in Drosophila ( <n>D-Cbl</n> ) .
96655039633>Fourteen healthy male volunteers completed the study .
80573566256>Comparisons of the four operon control regions studied indicate that the <n>NarL heptamers</n> are arranged with diverse orientations and spacing .
63008366603>Hybridization of plasmid-transformed Escherichia coli RR1 colonies with 32P-labeled viral genome RNAs demonstrated the presence of DNA clones representative of each of the 10 reovirus RNAs and 10 of the 11 constituent segments of the rotavirus genome .
31828021511>Sci .
82809255069>The secondary , but not the primary , antibody responses of male C57Bl / 6 mice were higher among mice housed alone compared to mice housed in groups ; differences were observed for both <n>IgM</n> and <n>IgG anti-KLH antibodies</n> .
104231563473>TaV particles have a buoyant density of 1 . 296 g / cm3 in CsCl and consist of two capsid proteins of 56 and 6 kDa .
94518579407>Demonstration of tissue lesions after intramuscular injection by determination of <n>creatine kinase</n> in blood .
91712399540>These six amino acids are part of an amphipathic helix that is highly conserved among <n>nuclear hormone receptors</n> and contains the core domain of the ligand-dependent transactivation function , <n>AF-2</n> .
90280898991>Therefore , it is important to control hypertension and keep appropriate renal blood flow during living renal transplantation surgery .
92902072411>Neither mutant exhibited derepression of the <n>silent mating type loci</n> .
85467073717>Transcriptional activation of the <n>chicken lysozyme gene</n> by <n>NF-kappa Bp65</n> ( <n>RelA</n> ) and <n>c-Rel</n> , but not by <n>NF-kappa Bp50</n> .
8479678446>Current diagnostic uses of computerized tomography in clinical medicine .
1013005232>59 cases of surgically resectable cancers ( T1 , T2 , T3 , N0 , N1 ) had a minimum followup of two years ( average 4 years + / - 3 months ) .
44950344994>Re-examining methylbenzene ( toluene ) as a treatment for Ancylostomum caninum .
34659574164>Mean fluorosis scores , however , were similar .
66720946434>The subgroup innervating the medial rectus lies exclusively along the medial face of the oculomotor nucleus , with no aberrant neurons in the medial longitudinal fasciculus , as have been found in other mammals .
256282577>Responsiveness to beta-2 agonist therapy was retained with both agents ( p less than 0 . 05 ) .
97510612083><n>POU-domain proteins</n> , such as the <n>pituitary-specific factor Pit-1</n> , are members of the <n>homeodomain family</n> of proteins which are important in development and homeostasis , acting constitutively or in response to signal-transduction pathways to either repress or activate the expression of specific genes .
20832534005>The <n>TCF-1 alpha binding site</n> was also required for <n>TCR alpha enhancer</n> activity in transcriptionally active extracts from Jurkat but not HeLa cells , confirming that <n>TCF-1 alpha</n> is a <n>T-cell-specific transcription factor</n> .
78621684043>The <n>interleukin 2 receptor alpha-chain</n> ( <n>IL-2R alpha</n> ) gene is rapidly and potently induced in T cells in response to mitogenic stimuli .
1498992114>Prediction of the times of sandfly development .
569019721>A mixture of <n>human albumin</n> 5% and hydroxy-ethyl-starch was used as a solution for dilution .
16797492387>The localization of this <n>proteoglycan locus</n> in the human genome and the availability of new RFLPs provide the tools for future studies of human diseases where the <n>HSPG2 proteoglycan gene</n> is suspected to be involved .
105710474169>Several <n>7SL RNA-encoding sequences</n> and various intergenic spacers were amplified from the individual <n>HindIII fragments</n> of about 1 . 3 and 2 . 8 kb .
97120378481><n>Tctex-1</n> binding required the first 19 amino acids of <n>Fyn</n> and integrity of two lysine residues within this sequence that were previously shown to be important for <n>Fyn</n> interactions with the <n>immunoreceptor tyrosine-based activation motifs</n> ( <n>ITAMs</n> ) of <n>lymphocyte Ag receptors</n> .
58590165777>Hydroxypropyl methacrylate , a new water-miscible embedding medium for electron microscopy .
10215485157>Significant correlations between mental status as measured by the Mini-Mental State Examination and NA / mI , mI / Cr and NA were found .
118652181755>Treatment for this condition often involves use of a wax softening or dispersing agent ( cerumenolytic ) before syringing .
78755957873>Like humans , the <n>PITSLRE PK genes in chickens</n> must be closely linked , based on fluorescent in situ hybridization ( FISH ) localization of these genes to a single chicken microchromosome .
80373386468>PURPOSE : To evaluate the kinetics of <n>erythropoietin</n> ( <n>EPO</n> ) production and address the pathogenesis of anemia of prematurity , we measured <n>EPO</n> levels in infants during the first year of life .
85366947477><n>Protein kinases</n> play pivotal roles in the control of many cellular processes .
97105997134>In the former cells , <n>ets-2</n> was a <n>CSF-1 immediate-early</n>1 <n>response</n>1 <n>gene</n>1 , and phosphorylated <n>ets-2</n> was detected after 2 to 4 h , coincident with expression of <n>ets-2 protein</n> .
97353717382>In particular , <n>unc-86</n> encodes a <n>POU-type homeodomain protein</n> needed for the production of the touch cells , while <n>mec-3</n> encodes a <n>LIM-type homeodomain protein</n> needed for the differentiation of the touch cells .
18759224532>Mutation analysis implicated multiple segments of the 5' untranslated region as contributing to the inhibitory effect .
44458744972>Pathology of neuritis caudae equinae in the horse .
36873134353>Two new <n>glucosidase</n> inhibitors ( BAY m 1099 and BAY o 1248 ) were studied in volunteers and type II diabetics under various conditions .
78363903740>The characteristics of the VirD1 / VirD2-mediated cleavage reaction strongly resemble those observed with relaxosomes of IncP plasmids involved in initiation of transfer DNA replication during bacterial conjugation .
13212805494>To define the number and nature of the <n>E6</n> and <n>E7 gene</n> products expressed in BPV-1-transformed cells , we performed immunoprecipitation experiments with antisera raised to bacterially expressed <n>BPV-1 E6</n> and <n>E7 fusion proteins</n> .
93252737985>These results suggest that <n>UBP41</n> may play an important role in the recycling of <n>ubiquitin</n> by hydrolysis of <n>branched poly-ubiquitin chains</n> generated by the action of <n>26 S proteasome</n> on poly-ubiquitinated protein substrates , as well as in the production of free <n>ubiquitin</n> from <n>linear poly-ubiquitin chains</n> and of certain ribosomal proteins from <n>ubiquitin fusion proteins</n> .
74950592869>Results of the ECAT Angina Pectoris Study Group .
78239195453>Conversely , activation of <n>Oct-3 / 4 promoter</n> by <n>RAR</n> : <n>RXR heterodimers</n> was completely abolished by <n>EAR-3 / COUP-TFI</n> and by <n>ARP-1 / COUP-TFII</n> .
61363745952>At both water temperatures , VO2 increased linearly with increasing swimming velocity .
80067727999>To see if a pulse oximeter can monitor the fetus during labour we recruited 100 Caucasian women in normal uncomplicated labour .
7499242625>In adult tissues , it was less restricted , indicating that <n>RAFTK</n> expression is developmentally up-regulated .
94276273340>A cytosolic variant of the protein underwent efficient transphosphorylation , yet failed to activate appreciably either <n>p70 ( S6k )</n> or <n>MAP kinase</n> following treatment with FK1012 .
9267519224>Recent studies have shown the rat larynx to be an important organ in the evaluation of irritancy of inhaled materials .
93598872278>Taken together , our data suggest that <n>Rat7p / Nup159p</n> is anchored within the <n>NPC</n> through its coiled-coil region and adjacent sequences .
13161255919>The experiment results showed : ( i ) not only 1O2 , but also free radicals ( O2- . . OH and YHPD- . ) can be formed by the aid of YHPD ; and ( ii ) as to the ability of producing 1O2 , YHPD less than BHPD , while for generating O2- . and . OH , YHPD greater than BHPD .
67944802455>There is now a significative difference between age group 1-5 and the others ( p Less Than 0 , 02 ) .
47041375102>Role of histoclinical studies in the prophylaxis of spontaneous abortions .
91221762786>Our results indicate that RA-mediated repression of the <n>hMGP gene</n> is due to binding of liganded <n>RAR / RXR</n> to a novel negative <n>RA response element</n> .
115740883047>The mean waiting time to receive the pancreas transplant was 244 days for SPK and 167 days for PAK recipients ( P = 0 . 001 ) .
86217304413>An <n>AP-1 binding sequence</n> is essential for regulation of the <n>human alpha2 ( I ) collagen</n> ( <n>COL1A2</n> ) promoter activity by <n>transforming growth factor-beta</n> .
106225746411>The prevalence of hepatitis C virus ( HCV ) infection is relatively low in childhood , with anti-HCV prevalence rates of 0 . 1-0 . 4% in the Western world .
2457922385>Hybridization of a probe from this region to electrophoretic blots of RNAs from different human tissues showed a predominant 2 . 8-kilobase ( kb ) message accompanied by weaker bands 4 . 1 and 2 . 1 kb in size .
21744273256>Both strains grew very poorly , or not at all , on nonfermentable carbon sources and exhibited , at most , only 5% of <n>wild-type ubiquinol-cytochrome c oxidoreductase</n> activity .
10962738783>Consciousness is connected with attention , working memory and perception .
114333793268><n>SIT</n> ( <n>SHP2-interacting transmembrane adaptor protein</n> ) is a recently identified transmembrane adaptor protein , which is expressed in lymphocytes .
85414994433>Certain transcript patterns in Epifagus plastids are highly complex and similar to those of tobacco operons .
3280946127>The putative immunity protein was detected among the [ 35S ] methionine-labelled proteins produced by minicells carrying <n>cni</n> cloned under <n>lac promoter</n> control , and when the gene was subcloned into expression vectors under the control of a bacteriophage T7 promoter .
86436464151>This region includes <n>verA</n> , a structural gene previously shown to be required for <n>ST</n> biosynthesis , and 24 additional closely spaced transcripts ranging in size from 0 . 6 to 7 . 2 kb that are coordinately induced only under ST-producing conditions .
25004322877>In transformed E . coli , <n>constitutive CAT</n> expression is maintained when as little as 0 . 3 kilobase of DNA from the 3' end of the 1 . 6-kilobase segment is inserted in the correct orientation in front of the <n>CAT gene</n> .
30025016535>Comparison of sequences of ovine and bovine , rat and <n>guinea-pig alpha s1-casein mRNAs</n> has revealed a greater homology in the 3' and especially 5' non coding regions .
72982096170>The determination of physical performance capacity was based on W170 , W85% and on predicted VO2 max measured with continuously increasing work load on a bicycle ergometer .
75017007099>The effects of a 1- or 24-hour pretreatment regimen with monophosphoryl lipid A ( MLA , 35 micrograms / kg i . v . ) on myocardial stunning produced by repetitive coronary occlusions were studied in barbital-anesthetized dogs .
33751844064>The spermicide nonoxynol-9 is a member of a homologous series of alkylphenol-ethoxylates ( polyethoxyethanols ) of general formula C9H19-C6H6-O- ( CH2CH2O ) n-1 CH2CH2OH .
1111749625>According to their functional properties the latter neurons were subdivided into : ( a ) neurons responding to stimuli near the eyes ; ( b ) neurons triggered by complex visual stimuli ; ( c ) neurons inhibited by visual stimuli .
82904215272>To our knowledge , type IV renal tubular acidosis has not been reported previously in association with Alport's syndrome in an adult patient .
97774773063>Observers with brain injury and control participants performed a vigilance task during which they received periodic whiffs of unscented air or air scented with peppermint .
78726736837>To explore the functional relationship between <n>c-fos</n> and <n>Rb</n> , a eukaryotic expression plasmid was constructed containing the <n>c-fos gene</n> under control of the SV40 promoter complex .
9704883552>The neuroleptic-induced increase in central DA turnover ( an indicator for the degree of <n>DA receptor</n> blocking ) was found to be positively correlated with the therapeutic effect of neuroleptics and the development of hypokinetic-rigid symptoms .
111313212485>Effects of Trypanosoma vivax on pregnancy of Yankasa sheep and the results of homidum chloride chemotherapy .
10906317732>The two main experimental variables were the attended hemifield ( left or right ) and the proportion of trials requiring a shift within that hemifield ( 20% or 80% ) .
86549461347>155 aa , shares 78% identity with the analogous region of Xenopus laevis <n>FGF3</n> and 72% identity with the product of the more distantly related human gene .
17403307005>J .
106886639886>Removal of all <n>core histone</n> tail domains by limited <n>trypsin</n> proteolysis or acetylation of the <n>core histone</n> tails significantly relieves this inhibition and allows <n>TFIIIA</n> to exhibit high-affinity binding to nucleosomal DNA .
98636248472><n>Agonist-induced receptor</n> internalization , determined as the percent of total [ 125I ] <n>Tyr0-oCRF</n> bound located in the acid-resistant fraction of transfected Cos 7 cells , increased with time ( 0-60 min at 37 degrees C ) for both wild-type and variant <n>oCRF1</n> .
29133686574>Pharmacology studies with potassium chloride and acetylcholine suggest that raveron acts as a calcium antagonist by blocking the influx of extracellular calcium .
79837164710>Surprisingly , Northern ( RNA ) blot analysis and reverse transcriptase-PCRs performed after transfection of COS-7 or HeLa cells with these viral RNAs revealed that <n>Y88S</n> and <n>Y88L RNAs</n> replicated at only very low levels .
15449285935>Comparison of the genomic DNA sequence with that of the four different mRNAs indicates that these transcripts are produced by alternative splicing of the murine pre-mRNA according to a cassette model .
104480952959>The <n>STAT protein</n> accumulation resulting from <n>C / EBP</n> expression was tightly coupled to the morphological conversion of fibroblasts to adipocytes and represents an expression profile identical to that reported for mature adipocytes in vivo .
10805390617>To illustrate its performance , measurements of photoluminescence in GaAs / AlGaAs heterostructures are presented .
76858235279><n>RNA polymerase</n> bound to the <n>+10A promoter</n> partially protects a 20 base-pair sequence from <n>DNase I</n> digestion upstream of the start site .
84300875647>Further , the ability of <n>recombinant beta and / or gamma chains</n> to function in defined biochemical assays of <n>beta gamma</n> activity was assessed for membrane extracts and supernatant fractions from infected Sf9 cells .
98823033696><n>TRAF2</n> is known to associate with <n>TRADD</n> , and expression of a dominant-negative N-terminal deletion <n>TRAF2 mutant</n> was found to partially inhibit LMP1-induced <n>JNK</n> activation in 293 cells .
2165589873>A portion of Region II also resembles part of the human <n>c-jun</n> oncoprotein's leucine zipper , which in turn , has been demonstrated to be the heterodimerization site between the <n>jun</n> and <n>fos oncoproteins</n> .
27753334604>Buflomedil ( i . v . ) induced a dose-dependent increase of cardiac output at 0 . 16-0 . 64 mg / kg , biphasic changes at 1 . 28 and 2 . 56 mg / kg and a marked decrease and subsequent slight increase at a large dose of 5 . 12 mg / kg .
63493646150>These results indicate that both naturally acquired and passive ( modified immune serum globulin ) antibodies to <n>type III group B Streptococcus antigen</n> are partially protective against intra-amniotic infection .
40797384763>The rates of total energy use ( mean + / - SD = 39 . 3 + / - 1 . 2 vs 35 . 7 + / - 1 . 3 kJ X min-1 ; P less than 0 . 05 ) were significantly higher at -10 degrees C than at 22 degrees C .
82469876615>In addition to the <n>protein-tyrosine kinase domain</n> , <n>p56lck</n> possesses <n>Src homology 2 and 3</n> ( <n>SH2</n> and <n>SH3</n> ) domains as well as a unique N-terminal region .
96680966926>Each binding site , however , was different in its preference for binding partners .
106304711692>An ASIC-chip for stereoscopic depth analysis in video-real-time based on visual cortical cell behavior .
10963577789>Picture the smell .
90069024696>We have isolated a cDNA encoding <n>human MEKK3</n> .
89551595257><n>Human acid ceramidase ( ( AC ) N-acylsphingosine amidohydrolase</n> , <n>EC 3 . 5</n> .
11278583771>Mutagenesis of <n>SNT1 ( IRS ) CX</n> identified three classes of effector motifs within <n>SNT</n> critical for both sustained <n>ERK</n> activation and neuronal differentiation : 1 ) four phosphotyrosine motifs that mediate recruitment of <n>Grb2</n> , 2 ) two phosphotyrosine motifs that mediate recruitment of <n>Shp2</n> , and 3 ) a C-terminal motif that functions by helping to recruit <n>Sos</n> .
37120503662>Indium-111 leukocyte imaging in patients with rheumatoid arthritis .
77741378530>The potential impact of using a rapid diagnostic test ( Strep A OIA ) on detection and treatment of group A beta-hemolytic streptococcal ( GABHS ) pharyngitis in a large-volume pediatric and adolescent clinic was examined .
32161318270>The only isolate of Aeromonas hydrophila produced cytotoxic <n>enterotoxin</n> and was invasive .
28768993581>On Days 1 and 14 , most young and elderly subjects exhibited monoexponential decline in bevantolol plasma concentrations after absorption phase .
67883887503>Although the mechanism of action of ICRF-159 and 187 has not been clearly defined , it is evident from both preclinical and early clinical studies that these compounds are of interest .
80659018519>Our results indicate that the <n>KRAB domain</n> present in the non-finger region of many <n>ZFP genes</n> quenches transcription possibly due to specific protein-protein interactions between the <n>KRAB-A domain</n> and components of the proximal transcriptional apparatus .
65242021526>A new variant of the EMG-BFB method ( multichannel ) is offered which has made it possible to use the method not only for training weakened muscles and reducing spasticity in their antagonists but also for improving motor coordination .
26317437059>We investigated the incidence of congenital color deficiency among Koreans by the use of H-R-R pseudoisochromatic plates .
67044676461>We suggest that sensitivity to photoperiod in pallid bats , as in several other mammals , is mediated by the pineal gland .
7575947970>The debate over electives--1899 .
8218338185>This report presents an analysis of the vocal repertoire of howler monkeys ( Alouatta palliata ) observed during a field study in southwestern Panama .
103334812521>Additionally , deletion analysis of the <n>UCP2 promoter-PLAP constructs</n> indicated that the minimal region exhibiting the promoter activity was located between nt -33 and +100 , and that a strong enhancer was present within 601 bp of the 5'-promoter region .
29959999103>The sequence analysis of both products of individual phi 80 site-specific recombination events in vivo shows that recombination with a secondary attachment ( att ) site generates several different novel joints at the mismatched position : one recombination event resulted in a single base-pair deletion and two other recombination events resulted in two different single base-pair substitutions .
110597869681><n>Epidermal growth factor receptor</n> transcriptionally up-regulates <n>vascular endothelial growth factor</n> expression in human glioblastoma cells via a pathway involving <n>phosphatidylinositol 3'-kinase</n> and distinct from that induced by hypoxia .
79644588358>A candidate gene for <n>Bcg</n> , designated <n>natural resistance-associated macrophage protein</n> ( <n>Nramp</n> ) , has been isolated and shown to encode a novel macrophage-specific membrane protein , which is altered in susceptible animals .
87946018779>The triple combination of nizatidine , clarithromycin , and bismuth subcitrate resulted in an ulcer healing rate of 98% and an H . pylori eradication rate of 90% .
105573088367><n>Connector enhancer of KSR</n> ( <n>CNK</n> ) is a multidomain protein required for <n>RAS</n> signaling .
84092845166>Continued absorption of amino acids by the NBB carrier ( for neutral amino acids ) , the Y+ system ( for dibasic amino acids ) , and the PHE carrier were operative even during the actively purging stage of watery diarrhoea due to cholera .
36123168987>Weaned rats were fed a normal diet or a low-protein , low-energy diet , and injected with saline or thyroxine ( 5 micrograms / 100 g BW ) for 22 days .
103610381451>They also occur in similar locations in the promoters of several other <n>ribosomal protein genes</n> .
111639681058>In the present work , the complete genome sequences of Pyrococcus horikoshii and Pyrococcus abyssi , two species in a genus of hyperthermophilic archaeon ( archaebacterium ) , were compared to detect large genome polymorphisms linked with <n>restriction-modification gene homologs</n> .
12871971929>For the first group , the maximal decrease in plasma potassium elicited by salbutamol was 0 . 80 + / - 0 . 19 , 0 . 48 + / - 0 . 22 , and 0 . 78 + / - 0 . 46 mmol / l , and for the second group , maximal decrement was 1 . 31 + / - 0 . 37 , 0 . 70 + / - 0 . 24 , and 0 . 84 + / - 0 . 17 mmol / l for the iv , po , and it routes , respectively .
91771699536>A similar chimera was assembled from the two halves of the molecule expressed separately in different bacteria and refolded together .
82324122761>The <n>lemdr1 gene</n> was cloned in the expression vector pALTNEO and transfected into wild-type L . enriettii and the resulting transfected cells were resistant to vinblastine but at lower levels than in the selected mutant cells .
95805639565>The predicted amino acid sequence is 78 . 0% identical to the <n>cytoplasmic dynein heavy chain of Neurospora crassa</n> , 70 . 2% identical to that of Aspergillus nidulans and 24 . 8% identical to that of Saccharomyces cerevisiae .
19681569763>Dose standardisation of <n>botulinum toxin</n> .
111161312605>These cells produced <n>P2Y ( 11 ) mRNA</n> during culture .
100228508588>In contrast , an amino-terminal fragment containing the <n>C / H1 domain</n> was sufficient for coactivation of <n>Zta</n> transcription and viral reactivation function .
32125513905>The pathogenesis of Dupuytren's contracture .
115958404458>The uptake of fluorine-18 fluorodeoxyglucose ( F-18 FDG ) by a malignant tumor depends on the blood glucose level .
104035755547>The inhibition of <n>StAR gene</n> transcription by <n>DAX-1</n> was dose-dependent reducing transcription to 6% of control levels .
7572582255>Mibefradil ( Ro 40-5967 ) is a novel calcium antagonist from a new chemical class and is the first that selectively blocks the T-type calcium channel .
21963118710>These results suggest that 5 KE X 3 / W may be the optimal regimen to augment the antitumor immunity of RNL .
95818343569>Taken together , these results suggest that silymarin may exert a strong anticarcinogenic effect against PCA and that this effect is likely to involve impairment of erbB1-SHC-mediated signaling pathway , induction of <n>CDKIs</n> , and a resultant G1 arrest .
79668737956>Articles addressing valvular heart disease or heart failure secondary to acute myocardial infarction or Chagas' disease were excluded .
95069625672>We further show that proteolytic targeting by <n>calpain II</n> and the proteasome involves different structural elements of <n>YY1</n> .
85177378483>These findings suggest that a range of microenvironmental conditions exist within purified water systems , leading to variable populations of bacteria .
10655230608>Like their yeast counterpart , the mouse <n>GCN2</n> isoforms contain <n>HisRS-related sequences</n> juxtaposed to the kinase catalytic domain .
74901564740>Vitamin D3 plus nicotine treatment produced parallel increases in cardiac mass and elastic modulus , with a significant correlation between the two .
75271687404>Microvessels were counted in a x200 field ( 0 . 754 mm2 ) in the area of maximal angiogenesis .
107023894481>In endemic BL , the <n>RB2 / p130 gene</n> is mutated in most of the cases , and the protein is restricted to the cytoplasm .
84016143265>French bean contains a small family of <n>genes encoding PAL</n> and two of these genes , <n>PAL2</n> and <n>PAL3</n> , have been shown to be differentially expressed at the mRNA level in bean tissues .
25778671795>The avian cellular homolog of the <n>oncogene jun</n> .
39238284570>The availability of cryoprecipitate and DDAVP offers an alternative and effective treatment for the temporary reversal of uremic bleeding in patients who require urgent invasive procedures .
88780198833>The intranodal mesothelial cells occupied the sinusoids of the lymph nodes and were initially suspected of being metastatic from the ovarian tumor in each case .
8204403209>A total of 7 ( 4 males and 3 females ) patients were included in this retrospective study to determine the sensitivity of radioimmunoscintigraphy with I-131 labeled anti <n>CEA / CA</n> 19-9 monoclonal antibodies .
22292821703>Patients with detectable serum <n>TNF</n> levels had significantly lower serum T3 concentrations compared to those with undetectable levels [ 1 . 072 + / - 0 . 588 vs .
118638118949>We find that the measured Nusselt number decreased about 20% over the range of Pr spanned in the experiment .
28375759754>Sodium dodecyl sulphate-induced cleavage by <n>eukaryotic topoisomerase I</n> is known to yield enzyme covalently attached to the 3' cut end of the DNA .
85438103629>To identify some of the genes expressed in LPS-activated coelomocytes , we sequenced randomly chosen clones from a directionally constructed cDNA library to produce a set of expressed sequence tags ( ESTs ) .
111520816179>Adding 10 mmol SDS / l led to transient inhibition of acidification , metal solubilization and sulfur oxidation .
92784416648>Overexpression of <n>CARP</n> in cardiomyocytes suppresses <n>cardiac troponin C</n> and <n>atrial natriuretic factor</n> transcription .
110560075533>It contained seven extra amino acids of <n>FVVLNLQ</n> ; this short stretch of extra sequence was found between Gln ( 421 ) and Phe ( 422 ) within the <n>SET</n> ( <n>Suvar3-9 , Enhancer-of-zeste , Trithorax</n> ) interacting domain ( <n>SID</n> ) of <n>rMTM</n> .
98206117060>Therapeutic use of continuous subcutaneous infusion of <n>recombinant human erythropoietin</n> in malnourished predialysis anemic patients with diabetic nephropathy .
68699867154>Circulating platelets may be activated by exposed triple-helical <n>collagen</n> in atherosclerotic lesions in Mg-deficient ruminants .
60848645901>Elevated <n>maternal alpha fetoproteins</n> and oligoamnios : fetal prognosis .
92280921582>These analyses demonstrate that the <n>dUTPase</n> isoforms are encoded by the same gene with isoform-specific transcripts arising through the use of alternative 5' exons .
9032267892>Overexpression of the bZip interaction domain of <n>CBP</n> specifically abolishes the positive cross talk between <n>TR</n> and <n>p45 / NF-E2</n> .
19249202547>Of these 179 samples , Mobiluncus SP was observed in 35 ( 19 . 6% ) using Gram staining and in 18 ( 10 . 1% ) this microorganism was isolated in agar RLK and anaerobic atmosphere .
82620413278>The <n>phi AP3 factor</n> is a nuclear phosphoprotein ; the extent of its phosphorylation is regulated during the cell cycle .
78573447843>As the half-life of the compound did never exceed 8-9 h , the data do not support any change of pidotimod administration schedule ( every 24-12 h ) .
23115445595>Studies also have alluded to a relationship between the MSMR cyst and certain signs or symptoms of disease .
83324922033>One member of this multigene family , <n>GATA-3</n> , is most abundantly expressed in T lymphocytes , a cellular target for human immunodeficiency virus type 1 ( HIV-1 ) infection and replication .
10595315422>There were minimal negative effects on hematological parameters , acid-base status , and blood gases .
105103797439>A crucial transcription factor in this process is <n>STAT6</n> , which binds to a specific DNA element upon cytokine activation .
7720709378>Using Ki-ras-transformed 3T3 cells as a model system , we show that both RA and the 'dissociating' retinoids inhibit anchorage-independent cell proliferation , suggesting that retinoid-induced growth inhibition may be related to <n>AP1</n> transrepression .
34480354154>Ovarian tumors in pregnancy .
87987624540>Altogether , our results indicate that the transcriptional activity of <n>Cut proteins</n> is modulated by <n>PKC</n> .
36870784351>References for occupational fitness of adolescents with diseases of the respiratory tract and lungs .
33089095673>Lysosomal enzymes that degrade cartilage are released .
98068261992>We have previously mapped the defect in RIIIS / J to distal mouse Chr 11 , distinct from the <n>Vwf locus</n> on Chr 6 .
30279053455><n>Plasma renin</n> activity rose and the plasma aldosterone level fell after taking lisinopril .
4885345226>In addition a significant Treatment X Strain interaction was due to the larger defecation numbers displayed by the taurine-injected MR rats relative to the saline-injected MR rats .
107752671048>Retroviral transduction of <n>T / T ( L )</n> causes a rapidly fatal myeloproliferative disease in a murine bone marrow transplant ( BMT ) model , whereas <n>T / T ( F )</n> causes a long-latency , pre-B-cell lymphoblastic lymphoma .
94596855443>Typical configurations of psychosocial stress factors of psychiatrically conspicuous children and adolescents .
790367099>The mutant allele of the <n>alpha 1-tubulin gene</n> was designated <n>tua1-1</n> .
111776861018>Treatment includes both medical and surgical options , with medical therapy further subclassified into pharmacologic and pneumatic dilation .
78166306762>Similarly approximately 300 bp of sequence downstream of the translation terminator TGA of the <n>beta-tubulin 2</n> ( <n>BTU2</n> ) gene could substitute for the 3' region of the <n>H4-I gene</n> .
85498597007>The gene was uniquely mapped with odds > 1 , 000 : 1 on chromosome 3p in Centre d'Etude du Polymorphisme Humain pedigrees .
112569446460>Furthermore , the soluble forms of <n>ATF6</n> and the <n>G13 gene product</n> are unable to bind to several point mutants of the cis-acting <n>ER stress response element</n> in vitro that hardly respond to ER stress in vivo .
38820295711>A retrospective study of banked sera from 19 cats with the eosinophilic granuloma complex revealed that 68% of affected cats had circulating antibodies to components of normal cat epithelium .
80905718067>Elimination of natural antibodies in discordant xenografts .
106012801872>The first one is a <n>TPA-responsive element</n> that controls the base-line <n>ST3 promoter</n> activity but is not required for its activation .
105518797224><n>Cyclic AMP-dependent protein kinase</n> binding to <n>A-kinase</n> anchoring proteins in living cells by fluorescence resonance energy transfer of green fluorescent protein fusion proteins .
110492411173>RESULTS : In the pregnant group , serum <n>PP14</n> concentrations were markedly increased after ET , and a significant difference between the pregnant group and the nonpregnant group was observed 8 days following ET ( p < 0 . 01 ) .
8552095934><n>Paf1p</n> may therefore be required for both positive and negative regulation of subsets of yeast genes .
25261658246>The sign of Leser-Trelat : does it exist ? The sign of Leser-Trelat is usually regarded as a reliable cutaneous marker of internal malignancy .
92185205609>We have initiated studies to identify candidate signal transducers that associate with the cytosolic domain ( cd ) of the <n>IL-1R</n> .
110718523740>To test whether or not <n>SOCS-3</n> also binds to the <n>IGFIR</n> , we cloned <n>human SOCS-3</n> by reverse transcription-polymerase chain reaction from human skeletal muscle mRNA .
88358957815>The <n>CD4</n> count at which remission occurs may reflect severe immunodeficiency such that risk for AIDS-related infection is high .
109610466815>Platelet counts and function as well as <n>fibrinogen</n> and <n>von Willebrand factor</n> ( <n>vWF</n> ) levels were determined in each sample .
109189433273>Developmental toxicity of the class III antiarrhythmic agent almokalant in mice .
77899715705>The absence of other regions of hybridization suggests that there are no closely related sequences ( e . g . , reverse transcribed pseudogenes ) scattered throughout the genome and that if there are closely related genes , they must be clustered near <n>GSTT2</n> .
113691061209>Recent advances have shown that volatile sulfur is a result of ecological interactions and transformation processes through planktonic food webs .
109319509649><n>Cdk2</n> and <n>MAPK</n> precipitates from untreated tumor lysates phosphorylated <n>recombinant wild-type p27</n> but not the T187A mutant in vitro .
105010342705><n>Ribonuclease</n> protection assays revealed that <n>hmg1</n> and <n>hmg2</n> are differentially expressed in a developmentally- and spatially-modulated manner during morphogenesis of specialized terpenoid-containing pigment glands in embryos .
113745593189>SERS spectra were obtained by vacuum evaporation and casting of p-NTP onto silver island films , and also from colloidal silver solutions .
34407802974>From these results , it is concluded that EDLF has clear vasoconstrictor properties which are not due to adrenergic or calcium entry mechanisms and that there are differences in the vasoconstrictor effects of EDLFs with respect to different vascular beds .
80653665508>Taken together , our data suggest that <n>Dbf8p</n> plays an essential role in chromosome segregation .
29680553682>The HOI induced a nearly fourfold increase in <n>ANF</n> in the elderly , whereas that for the young was threefold .
15872672790>The sequence data now permit a detailed interpretation of the X-ray crystallographic structure of the enzyme and the cloning and expression of the clostridial gene will facilitate site-directed mutagenesis .
39566474608>Dissolution of the Pt-30%Ir microelectrode tip was observed by scanning electron microscopy at charge densities as low as 200 microC / cm2 X ph ( 1 A / cm2 ) , whereas erosion of activated iridium microelectrodes occurred only at the highest charge and current densities ( 3200 microC / cm2 X ph , 16 A / cm2 ) .
71074626910>The steepness of the standard O2 dissociation curve becomes greater during the training period ( increase in Hill's n from 2 . 68 + / - 0 . 10 to 2 . 96 + / - 0 . 15 ) .
14362614294>Subcutaneous administration of the <n>somatostatin</n> analogue , octreotide , 100 micrograms thrice daily , resulted in a sustained improvement in diarrhoea and disappearance of faecal incontinence without reducing <n>calcitonin</n> levels .
75994497500>The fracture groups were significantly older and had more years since menopause than the control groups .
102314547606>Total serum calcium was 7 . 8 + / - 0 . 8 mg / dl , whereas ionized calcium was 5 . 7 + / - 0 . 7 mg / dl , phosphorus 3 . 2 + / - 1 . 2 mg / dl , and <n>alkaline phosphatase</n> 149 + / - 48 . 6 U / liter .
96411677983>CONCLUSION : <n>TNF alpha</n> , <n>TGF beta</n> , <n>PDGF</n> and <n>IL-1beta</n> increased <n>LDLr gene</n> expression by increasing sterol-independent and mitogenesis-independent gene transcription .
45516504385>Cell viability and lysosomal enzymes .
57693072452>Automatic view box .
94789718657>Reporter constructs function in a parallel manner , demonstrating the key role of the <n>AhR</n> in constitutive as well as TCDD-induced expression of <n>Cyp1B1</n> in mouse embryo fibroblasts .
10442493287>At baseline , serum levels of lycopene and FLOP were abnormally high and serum FLOP was correlated significantly with plasma cyclosporine levels ( r = 0 . 646 , p = 0 . 016 ) .
73413467193>2 . numerous narrow shunt vessels departing continuously from the primary arteries to feed a secondary arterial system which parallels the primary one .
111132015904><n>Pmt2</n> is a member of a six-protein family in yeast that catalyzes the first step in O mannosylation of target proteins .
86611166823>Promoter activity was high in cell lines that expressed high levels of endogenous <n>D3 mRNA</n> , as indicated by Northern blot analyses , and was significantly reduced when the promoter was truncated to -122 bp .
14066887611>Sequencing analysis has shown that each <n>rap1t allele</n> contains a nonsense mutation within a discrete region between amino acids 663 and 684 .
93715669538>This protein is present in both HeLa nuclear extracts and S100 extracts but absent from <n>SR protein</n> preparations , suggesting that it is not a classical <n>SR protein</n> .
112787132389>Finally a 10-nucleotide region flanking the exon 4 protein-binding site is homologous to instability elements within five other transcripts , suggesting that a common coding region determinant may exist .
65273793205>Alternating proline / alanine sequence of <n>beta B1 subunit</n> originates from a repetitive DNA sequence .
87312226037>The distribution and organization of projections from the spinal cervical enlargement to subnucleus reticularis dorsalis ( SRD ) and the neighbouring Cuneate nucleus ( Cu ) area was studied in the rat by using microinjections of <n>Phaseolus vulgaris leucoagglutinin</n> ( <n>PHA-L</n> ) into different laminae around the C7 level .
75406076792>Retreatment of these 2 dogs resulted in a similar , but blunted , response to <n>human immunoglobulin</n> .
88638245775>Cloning and sequence analyses revealed a second cDNA with a 95-nt deletion in the region coding for the putative second intracellular loop and the fourth transmembrane domain of the <n>5-HT2C-R</n> .
27316717975>The relative toxicity of nickel oxide ( NiO ) , nickel sulfate hexahydrate ( NiSO4 . 6H2O ) , and nickel subsulfide ( Ni3S2 ) was studied in F344 / N rats and B6C3F1 mice after inhalation exposure for 6 hr / day , 5 days / week , for 13 weeks .
3887769139>In the region Walgau with mixed industrial-rural population an iodine deficiency I was found in 81% and an iodine deficiency II in 45% .
13711815123>We propose that plasmids of the pLS1 family ( pE194 , pADB201 , and pLB4 ) share functional and structural characteristics for the regulation of their copy numbers .
27621986086>Reye's syndrome : reports of 7 cases in the period 1982-1987 .
91033829048>The new FIGO definition of cervical cancer stage IA : a critique .
32769243167>In one of these tumors the observed rearrangement was not due to the insertion of an intact MoMuLV provirus .
62514691789>Among six different library isolates containing <n>6 . 5- to 7-kb IAP units</n> , some restriction sites were highly conserved whereas others varied in both occurrence and position .
62235863835>Immunochemotherapy with schizophyllan ( SPG ) combined with chemotherapeutic agents was evaluated in two syngeneic tumor-C3H / He mouse systems .
115332388747>Mutation of the octamer element also significantly reduced the ability of <n>HDAC1</n> to confer repression of inducible <n>HLA-DRA promoter</n> activation .
79772399293>Outflow obstruction of pancreatic juice , i . e . , "relative stenosis of the minor papilla , " was considered to be present in the patients with type II papilla , and , therefore , the patients with type II papilla might suffer from acute pancreatitis resulting from poor drainage of pancreatic juice and excessive pressure in the dorsal duct .
35101851393>Natl .
752950429>Pharmacological and pharmacokinetic characteristics of the non-ionic monomeric X-ray contrast agent iopromide ( Ultravist , CAS 73334-07-3 ) were evaluated in preclinical studies .
86082222888>The membrane-distal cytoplasmic region of <n>human granulocyte colony-stimulating factor receptor</n> is required for <n>STAT3</n> but not <n>STAT1 homodimer</n> formation .
100909439186>The mean value of the <n>CD79b</n> to the <n>CD79b</n> internally deleted ratio was 0 . 64 + / - 0 . 20 SD in normal donors and 0 . 44 + / - 0 . 27 SD in B-CLL ( P = . 01 ) .
28377632631>Amino acid sequence of one human liver clone ( HL-14 ) was identical to the <n>rabbit skeletal muscle phosphatase 2A cDNA</n> ( with 97% nucleotide identity ) .
105535518761><n>Factor XI</n> deficiency is a rare hereditary bleeding disorder affecting the intrinsic pathway .
82256578202>The effect of ibopamine and furosemide in 130 patients with NYHA Class I and II heart failure were studied in a parallel , double-blind , randomized placebo-controlled multi-centre trial .
85954143461>The assembly of sequence ready , high-resolution physical maps and construction of minimally overlapping contigs for the human as well as model genomes requires accurate determination of the extent of overlap between adjacent clones as well as their relative orientation .
3280021981>The SSB-poly ( dT ) affinity is too high to measure in buffers containing even 5 M NaCl ; however , in 1 . 8-2 . 5 M NaBr , we measure alpha log Kobsd / alpha log [ NaBr ] = -5 . 7 + / - 0 . 7 , with a lower value of omega T / O = 130 + / - 70 .
118461677119>Selenium is an essential element for humans , animals and some species of microorganisms .
108118044935>Consistent with this , we show that peptides representing docking sites within the target substrates <n>Elk-1</n> and <n>p90 ( rsk )</n> inhibit ERK-dependent activation of <n>MKP-3</n> .
68728002230>Acute type A hepatitis in three patients with chronic HBV infection .
24773731672>A potential TATA box is located 29 base pairs upstream of the first transcription initiation site .
3392894087>Use of radioactive isotopes in the chemistry of proteins .
88876597703>Mutations at two neighboring sites , serine 242 and threonine 255 , exacerbated the effect .
842758382>Preface .
27323419449>Light microscopical and routine immunohistochemical studies of a cervical neoplasm in a 32 year old woman initially suggested a histiocytic lymphoma , but histochemical staining for <n>chloroacetate esterase</n> established the correct diagnosis .
29273913587>All of the newly acquired proviruses identified in mosaic founder <n>SWR / J-RF / J</n> mice that could be transmitted through the germ line were also present in somatic tissues , demonstrating that viral integration occurred before the germ line was set aside from the somatic lineages .
99037229910>Autoionization rates and energy levels of triplet nf , v = 1 Rydberg states of H2 .
114419521316>At 20 days ( D ) and at 3 months post-TBI , irradiated rats had a significantly lower percentage of avoidance than controls but no statistical difference was found at 5 months post-TBI . b / Two-way avoidance test : this test was performed only after TBI .
40403394715>Monitoring changes in the heart rate of the premature fetus during tocolysis with the beta-adrenomimetics partusisten and Pre-par .
66436126378>Thin-layer chromatographic methods were up-dated for pharmacokinetic studies of imipramine in plasma and urine .
10502216298>This study was designed to compare the efficacy of efegatran plus <n>streptokinase</n> versus heparin plus accelerated <n>tissue plasminogen activator</n> ( <n>TPA</n> ) in coronary reperfusion in acute MI .
95568619512>Based on the current literature , the mechanisms involved in the toxicity of OA indicate three major effects : ( 1 ) inhibition of mitochondrial respiration correlated with a depletion of ATP ; ( 2 ) inhibition of <n>tRNA-synthetase</n> accompanied by a reduced protein synthesis ; and ( 3 ) enhanced lipid peroxidation .
114355783451>And , most importantly , reconstitution of a <n>consensus CRE</n> , within the 21-bp enhancers increases binding of <n>CREB / ATF proteins</n> but abrogates basal repression of LTR-directed transcription in vitro .
71754746997>The cause of death is often quite apparent from the pathological and toxicological findings ; however , the manner of death often gives the examining official some difficulty .
64608896265>In doses of 0 . 03-0 . 3 mg / kg i . v . , SG-75 did not significantly affect pulse pressure , heart rate , aortic blood flow , left ventricular pressure ( LVP ) and LVdP / dt max .
106471771411>The RNA aptamer contains three stems separated by a pair of two-base bulges , and adopts an unanticipated fold in which both junctional sites are anchored through base triple formation .
29823326509>Phase II study of VP-16 ( capsule ) in solid tumors .
80839981866>These results suggest that leader-mRNA fusion in coronavirus transcription does not require direct RNA-RNA interaction between complementary sequences .
108731581167>Activation of <n>nuclear factor ( NF ) -kappaB</n> and subsequent proinflammatory gene expression in human airway epithelial cells can be evoked by oxidative stress .
94227275507>A <n>cAMP-responsive element-like</n> ( <n>CRE-like</n> , <n>TGACGTGA</n> ) promoter sequence and a <n>protein kinase A</n> signaling pathway are involved in this induction , and activation of both <n>CRE binding protein</n> ( <n>CREB</n> ) and <n>activating transcription factor-2</n> ( <n>ATF-2</n> ) is required in the above process .
63743696175>These data suggest that a major part of the reduction in food intake in hyperphagic rats eating a quinine-adulterated diet is due to postingestional events .
90102237842>Similarly , we examined whether the <n>ELK1</n> , <n>SAP1a</n> , <n>FLI1</n> , <n>EWS-FLI1</n> , <n>ETS1</n> , <n>ETS2</n> , <n>PEA3</n> and <n>PU . 1 proteins</n> can form ternary complexes with <n>SRF</n> on the <n>Egr1 SREI</n>1 <n>and</n>1 <n>II</n>1 .
93684199642>In Arabidopsis , the induction of a <n>dehydration-responsive gene</n> , <n>rd22</n> , is mediated by abscisic acid ( ABA ) and requires protein biosynthesis for <n>ABA-dependent gene</n> expression .
91505957158>Like the elicitors of the hypersensitive reaction ( HR ) produced by E . chrysanthemi ( HarpinEch ) and E . amylovora ( HarpinEa ) , the deduced 36-kDa protein does not possess a typical signal sequence , but it contains a putative membrane-spanning domain .
89938312214>During skeletal muscle development , different types of muscle fibers are generated , which express different combinations of muscle-specific gene products .
94887132763>This resulted in a complete inhibition of Site-1 cleavage that was restored by concomitant overexpression of full-length <n>SCAP</n> .
84470058407>Elimination of Haemophilus influenzae type b meningitis after introduction of vaccination .
97074985614>MK-801 administration resulted in a biphasic response in seizure latency .
82620676209>The functional homology of <n>Cwg2</n> with <n>Cdc43</n> , which has been implicated in the control of cell polarity , suggests a link between two morphogenetic events such as establishment of cell polarity and cell wall biosynthesis .
88810364785>Using anchored PCR , a <n>VL element</n> rearranged to <n>CL2</n> was isolated .
111524513242>The <n>Schistosoma mansoni homologue</n> ( <n>SmSmad2</n> ) was overexpressed in bacteria as a <n>Sj26-GST fusion protein</n> and used to raise specific antibodies .
86555555439>In addition , 5' deletions removing all but 34 bp upstream of the transcription start point retained greater than 90% promoter activity , suggesting that the -35 hexamer was not essential for promoter activity .
29075333612>This loss was independent of drug concentration and a correction factor was employed to calculate the true free diazepam concentration .
112891351171>Coexposure to FP also resulted in a more pronounced and sustained activation of the <n>mitogen-activated protein kinase kinase / extracellular signal-regulated protein kinase</n> cascade after PMA treatment , although disruption of this pathway by the <n>mitogen-activated protein kinase kinase 1</n> inhibitor U0126 did not prevent potentiation of apoptosis .
95823082106>Indeed , it is shown that it mediates the formation of disulfide-linked homodimers and that the formation of homo- and heterodimers are mutually excluded .
16746623764>We enrolled 253 <n>HIV-antibody</n> positive heroin addicts without HIV-related disease ( n = 81 ) or with persistent generalized lymphadenopathy ( n = 172 ) in a prospective study to evaluate clinical progression to AIDS related complex ( ARC ) or AIDS and to identify factors of possible prognostic relevance .
90583734599>Functional tests using a reporter gene , containing <n>Stat5-binding elements</n> , confirmed that while the variant form was inactive by itself , it could inhibit the function of the full-length receptor .
91650395769>The <n>monkey LHR cDNA</n> displayed 83-94% overall sequence homology with the other <n>mammalian LHR cDNAs</n> .
115669481440>In hypertensive nephrosclerosis , therapy containing an ACEI alone or in combination significantly reduces the incidence of renal events .
14576952068>Removal of <n>beta 2-microglobulin</n> by hemodialysis and hemofiltration : a four year follow up .
12955004147>Most of the patients presented with Transient Ischemic Attacks ( 64% ) or Reversible Ischemic Neurologic Deficits ( 19% ) .
27788738148>Another segment of <n>CRL3</n> ( -296 to -184 ) , also displaying enhancer function , contained tandem repeated sequences ( <n>DR-A1</n> and <n>DR-A2</n> ) .
112357771066>In Klinefelter's syndrome ( 47XXY ) , serum testosterone levels are at the lower end of the normal range and dihydrotestosterone levels are low .
28447977207>Whereas the muscle isoform consists of 997 amino acids and terminates with the <n>sequence Ala-Ile-Leu-Glu</n> , the second isoform is 1043 amino acids in length due to the replacement of these last 4 amino acids with a 50-amino acid sequence that contains a potential transmembrane domain followed by a consensus sequence for an N-linked glycosylation site .
17144523416>Homology with the human protein is only 34% in the tandem repeat domain , mainly showing conservation of serines and threonines , presumed sites of O-linked carbohydrate attachment .
4787145159>Efficacy of a three- versus a five-week alcohol treatment program .
10407184676>An overexpression of the <n>betaAPP gene</n> in certain areas of the AD brain has been suggested to be an important factor in the neuropathology of AD .
93248788820>Widening of the abdominal aortic wall on an ultrasound examination was the key to the incidental diagnosis of a clinically unsuspected type B dissection .
40887335638>Activity of <n>acid hydrolases</n> of peripheral blood leukocytes in focal and segmental pneumonia in children .
4236494872>These techniques have been used by many people for many years and no claim is being made for any innovation in this regard .
114132771029>In conclusion , primary chemotherapy based on high dose MTX and ara-C is highly efficient in PCNSL .
16154931221>His <n>HC II</n> activity and antigen levels were 49% and 50% , respectively , and his daughter also showed similar low levels .
88538937618>In this study , we identified four distinct <n>E2F complexes</n> present in aged and senescent normal , human diploid fibroblasts .
97334939712>Our results show that , from a thermodynamical standpoint , melatonin may directly scavenge hydroxyl radicals both in vacuum and in aqueous solution .
15189268894>Selected topics in pediatric ultrasonography--1992 .
107787571955>We report here on the molecular nature of an EMS-induced mutant , <n>mn1-89</n> , a leaky semidominant allele of the <n>Miniature1</n> ( <n>Mn1</n> ) seed locus that encodes a <n>seed-specific cell wall invertase</n> , <n>INCW2</n> .
85567072989>These data indicate that although 218leu retains normal transactivation activity on a <n>p53 promoter</n> in yeast at physiological temperatures , it is not capable of normal <n>p53</n> function in the presence of a <n>248trp allele</n> in SNU-C5 cells .
76076077508>Increase in urinary calcium and oxalate after fructose infusion .
95083775157>These results would suggest that a high UV sensitivity is associated with high phaeomelanin and low eumelanin levels , and point to the eumelanin / phaeomelanin ratio as a novel chemical parameter that could be used for predicting individuals at high risk for skin cancer and melanoma .
116873528359>METHODS : This retrospective review comprised 2711 eyes that had LASIK between September 1996 and September 1999 .
85677177200>The Saccharomyces cerevisiae spindle pole body duplication <n>gene MPS1</n> is part of a mitotic checkpoint .
18620272457>These features were considered consistent with a diagnosis of Rothmund-Thomson syndrome .
93676764667>Transfection analyses indicated that the expression of <n>Tbxas1</n> is controlled by a short ( 70-bp ) positive regulatory sequence and several upstream repressive elements .
40814254765>Clinical aspects and therapy .
43089794917>Effect of variations in time interval between treatment with BCG and quartz dust on translocation of quartz dust from the lungs to their regional lymph nodes .
41750074837>To the problem of the stimulation of the growth of transplantable tumors of animals previously treated with antineoplastic antibiotics .
23320182429>Despite the absence of exercise-induced asthma ( EIA ) while breathing WH air , asthmatic patients still had significantly higher mean GH increments than normal subjects ( 9 . 2 vs 2 . 3 ng / ml , P less than 0 . 05 ) .
117324171578>The cut-off percentage positivity value was established using 500 brucellosis-positive and 500 brucellosis-negative serum samples , confirmed with reference to the sample data using the indirect ELISA kit .
94056851876>As a sequence-specific DNA binding transcription factor , <n>p53</n> specifically binds to a <n>20-bp consensus motif 5'-PuPuPuC ( A / T ) ( T / A ) GPyPyPyPuPuPuC ( A / T ) ( T / A ) GPyPyPy-3'</n> .
9931216815>Airflow was measured with a custom-designed turbine and a 45-ft . -long cable to reach the volume-measuring module .
63101591705>Viral RNA , molecularly cloned proviral DNA , and virus-specific protein of avian retrovirus MH2 were analyzed .
77232477676>To study the mechanisms as well as magnitude of the transmembrane transfer of bacterial products from the dialysate , we developed a computerized in vitro dialysis model which provides continuous pressure recording from the arterial , venous , dialysate inflow and outflow ports .
109321967424>Mutations in the <n>RP2 locus at Xp11 . 3</n> were found in a further 10-20% of XLRP patients , as predicted from linkage studies .
64677976272>There was a close correlation between plasma clearance of NT by 10-hydroxylation and the D metabolic ratio ( D / 4-OH-D in urine ) in the Ghanaians ( rs = -0 . 95 ; P less than 0 . 01 ) and Swedes ( rs = -0 . 84 ; P less than 0 . 01 ) .
10520800353>METHODS : We studied 20 symptomatic patients with HOCM ( 12 men ) , mean age 52 + / - 17 years , before and after septal reduction using echocardiography and electrocardiogram ( ECG ) .
90552213679>The intensity of the SSTEs is an order of magnitude larger than that of the MSEs and determines the signal contrast if both effects are selected simultaneously .
10932329748>The limit between the cecum and the ascending colon was externally marked by the sulcus cecocolicus dorsalis and ventralis .
114309768409>Special issues devoted to the biosynthesis of woody plant biopolymers and related substances .
100686373366>Interestingly , <n>Csx / Nkx2</n> .
95965369551>Consequently , it is not known how knee loading changes following ACL transection , and how it contributes to cartilage degeneration .
87700215321>Increased <n>PTHRP</n> production by a <n>tyrosine kinase oncogene</n> , <n>Tpr-Met</n> : role of the <n>Ras</n> signaling pathway .
16783922534>The 95% confidence values ( 2SD ) for the change in Ros required to exclude natural variability were 0 . 39 , 0 . 50 and 0 . 53 cmH2O l-1 s , respectively .
88876781986>Expression of the <n>proapoptotic protein Bax</n> under the control of a <n>GAL10 promoter</n> in Saccharomyces cerevisiae resulted in galactose-inducible cell death .
94070263583>TSA treatment , however , did not detectably alter enhancer factor binding or the positioning of <n>nuc-1</n> on the majority of the chromatin templates indicating that protein acetylation and chromatin remodeling may be limiting steps that occur only on transcriptionally competent templates , or that remodeling of <n>nuc-1</n> requires additional factors .
63099696095>I .
102285618286>We analyzed the modular organization of <n>DNA polymerase beta</n> and found that residues making contact with DNA phosphates were localized to five modules .
11710201552>The effects initiated from the nucleus accumbens septi were most marked .
91547951638>Using various techniques , we have undertaken a systematic analysis of the natural TATA-less <n>human DNA polymerase beta</n> ( <n>beta-pol</n> ) gene promoter .
2195651959>The incidence of <n>hepatitis B antigen</n> following transfusion was about 2 . 8 per cent .
2102202701>Molecular neurochemistry of addictive drugs .
1541556186>Radiolabelled palmitate was not incorporated into the mutated protein , showing that lipid modification occurs at the Cys-22 residue .
96730379643>METHODS : Fibrotic changes involving bone marrow were evaluated histologically semiquantitatively using reticulin fiber impregnation ( method of Gomori ) .
106825707812>LPO and <n>SOD</n> levels were measured at five points before and during the operation .
2800435752>Acute experiments on nembutal-anesthetized cats ( 50 mg / kg ) were employed to investigate the effect of 1 T pulsating magnetic field ( PMF ) on neuromuscular system of the leg .
23738104405>In contrast , 2 , 397 ( 74% ) had one or more risk factors ( not low risk ) ; of these , 5 . 3% died in 6 weeks ( p less than 0 . 001 ) .
91173457826>Activation of <n>alpha 4 beta 1</n> with <n>TS2 / 16</n> inhibited the cytoplasmic protrusions and cell migration but did not affect the pattern of phosphorylation .
19061666993>Mitomycin-C can cause severe necrosis and ulceration when extravasated inadvertently into skin and soft tissues following IV drug administration .
85504603438>The transposon-inactivated gene , designated <n>pilP</n> , is 525 bp long , potentially encoding a 19 . 1-kDa protein precursor that contains a typical membrane lipoprotein leader sequence .
61303485949>Isolation of Aeromonas from faeces .
29679156342>The seco-steroid hormone 1 , 25-dihydroxyvitamin D3 is known to induce the expression of a calcium binding protein termed <n>calbindin-D28K</n> in a variety of target tissues .
90016678960>In all cases the antigenemia was transient and cleared by 28th day post-vaccination .
90291596625>The <n>interferon</n> ( <n>IFN</n> ) -induced <n>double-stranded RNA ( dsRNA ) -activated Ser / Thr protein kinase</n> ( <n>PKR</n> ) plays a role in the antiviral and antiproliferative effects of <n>IFN</n> .
111184406492>Differential association of products of alternative transcripts of the candidate <n>tumor suppressor ING1</n> with the <n>mSin3 / HDAC1 transcriptional corepressor complex</n> .
8139577540>Identical components of yeast <n>transcription factor IIIB</n> are required and sufficient for transcription of TATA box-containing and TATA-less genes .
91124006947>DNA-binding activity was not increased by the addition of forskolin to thecal or luteal cells .
974998822>Badcock and Westheimer ( Spatial Vision 1 ( 1 ) , 3-11 , 1985 ) showed that a thin vertical line induces nearby zones of attraction and repulsion ; this study extends those results by more closely examining the horizontal and vertical extents of the repulsion zone and by using an illusory contour to induce repulsion .
90240398988>Forty-one ASA physical status I or II adult patients undergoing a variety of 1-1 . 5 h surgical procedures were randomly allocated to receive CCA with desflurane or isoflurane with ventilation being either spontaneous or controlled .
107756239580>The codon usage is particularly marked for the <n>gag</n> , <n>pol</n> , and <n>env genes</n> .
18552552552>Premature initiation of mitosis in yeast lacking <n>RCC1</n> or an interacting <n>GTPase</n> .
95125596563>Position-independent expression of a <n>human nerve growth factor-luciferase reporter gene</n> cloned on a yeast artificial chromosome vector .
1978857990>Judicious use of laboratory testing , including monitoring of <n>CD4</n> cell counts , is recommended .
22666792904>Plasma Al was obtained during each baseline and drug course .
53891255519>The exploratory behaviour in normal and aggressive mice .
10102000767>31 , 1997 , 40 patients had died ( 35 in the ERA-II group and 5 in the ERA-III group ) , for a crude mortality rate of 8 . 0% .
18235242427>The relatively scanty number of examples , which could be justified by the variety and complexity of combined exposure , allows to conclude that life-style factors have considerable influence on interindividual differences in susceptibility to xenobiotics toxicity .
90411233199>However , the action of each cognate ligand and the accessory cellular factors that can differentially regulate the transcriptional responses of a heterodimer-DNA complex are not well understood .
196255918>REM dream content was scored for categories suggesting the predominant influence of the left hemisphere , e . g . , good ego functioning , verbalization , or the right hemisphere , e . g . , music , spatial salience , bizarreness .
103205796419>We suggest that <n>FlgN</n> and <n>FliT</n> are substrate-specific flagellar chaperones that prevent oligomerization of the <n>HAPs</n> by binding to their helical domains before export .
86210174911>LY290181 appears to inhibit <n>uPA promoter</n> activation by blocking phorbol ester-stimulated binding of nuclear proteins to the <n>uPA PEA3</n>1 <n>/</n>1 <n>12-0-tetradecanoylphorbol</n>1 <n>13-acetate</n>1 <n>responsive</n>1 <n>element</n>1 ( <n>TRE</n> ) .
72824447137>Forty-five cases were surgically by direct approach to the tumour , while two cases were treated only with a shunt .
18046719256>In line with the small values for QS / QC , our results further indicate that even large , well-perfused , occluded air spaces in the lung will hardly affect the recovered ventilation / perfusion distribution obtained from inert gas data when CDCSF6 exceeds 0 . 1 ml . min-1 . mmHg-1 .
5191735427>All 13 patients showed endoscopic evidence of oesophagitis , moderate in 4 and severe in 9 .
75435923864>A transformation-competent mutant , like the <n>wild-type E5 protein</n> , bound the receptor and induced receptor tyrosine phosphorylation and down-regulation .
98587457415>The location of the IBS within the <n>catB structural gene</n> , the cooperativity observed in footprinting studies and phasing studies suggest that the IBS participates in the interaction of <n>CatR</n> with the upstream binding sites by looping out the intervening DNA .
88251789223>The initial inpatient experience for individuals with HIV-related TB may be pivotal to the acceptance of and participation in ongoing TB care .
89001647605>T . , Patel , S .
79289543366>DNA sequence analysis showed that the gene was 525 bp long and encoded a 175-amino-acid protein with a molecular weight of 19 , 094 containing a 21-residue typical lipoprotein signal peptide and consensus prolipoprotein processing site .
17319339489><n>Zn ( II ) coordination domain mutants of T4 gene 32 protein</n> .
28466403668>All of the indigo-producing bacteria had an <n>indoxyl phosphatase</n> with a pI of 6 . 4 .
84900028450>Xylose- and arabinose-containing polymers were better digested than was <n>cellulose</n> for both breads .
91547977622>Saturable spermidine transport in <n>stk2</n> : : <n>lacZ mutants</n> had an approximately fivefold-lower affinity and twofold-lower Vmax than in the parental strain .
112550356931>Unlike other progenitor cells of the brain , SVZa progenitor cells have the capacity to divide even though they express a neuronal phenotype .
98379071624>The decrease of <n>TNF receptors</n> by <n>IL-4</n> was accompanied by down-regulation of TNF-induced activities , including cytotoxicity , <n>caspase-3</n> activation , <n>NF-kappaB</n> and <n>AP-1</n> activation , and <n>c-Jun N-terminal kinase</n> induction .
107584899268>Here we report on the isolation of <n>ICK2</n> , and show that it interacts with <n>Cdc2aAt</n> , but not with a second <n>CDK from Arabidopsis</n> , <n>Cdc2bAt</n> .
105266703607><n>Rac</n> causes uncapping of <n>actin filaments</n> ( <n>F-actin</n> ) at the plus-ends , through phosphatidylinositol 4 , 5 bisphosphate ( PIP2 ) , and eventually induces membrane ruffling .
93094575845>Assays of total cholesterol as well as the <n>HDL</n> , <n>HDL2</n> , <n>LDL</n> , triglycerides , <n>endothelin-1</n> , <n>lipoprotein ( a )</n> , estradiol and <n>FSH</n> were also obtained at baseline before receiving ERT and after 3 months of ERT .
76156344522>These transcripts have a unique 5'untranslated region and NH2-terminal sequence and encode a predicted protein of 121 kD .
99228565886>Trinipatch is a small , transparent , matricial , monolayer patch with an absorption promoter , marketed in two dose-strengths ( 5 mg / 24 h and 10 mg / 24 h ) by Laboratoires Synthelabo .
90052735159>CONCLUSION : Some Gulf War veterans may have delayed , chronic neurotoxic syndromes from wartime exposure to combinations of chemicals that inhibit <n>butyrylcholinesterase</n> and <n>neuropathy target esterase</n> .
78571637838>The activity of 6-fluoroquinolones and their nonfluorinated derivatives is compared in general .
23271597291>Lars has AIDS--a more dignified life with care at home .
86571573951>Transcriptional regulators utilizing the <n>POU domain</n> DNA-binding motif have been shown to form multi-protein complexes dependent on the <n>POU domain</n> itself and its flexible recognition of various octamer sequence elements .
90508676209>These elements comprise a binding site for <n>Krox proteins</n> , one for <n>nuclear factor 1</n> , an octamer motif that binds <n>POU-homeodomain proteins</n> , and a novel <n>TN control element</n> .
67403736503>In this study the splenectomized captive born cynomolgus appeared to be capable of supplementing rhesus as an antimalarial drug testing model .
32324101922>It has been calculated that 600 , 000 new cases of lung cancer occur worldwide every year , most of them due to smoking .
113697009455>In this manuscript we demonstrate that two <n>tandem Ets sites</n> in the <n>mouse GL alpha promoter</n> bind the <n>transcription factors Elf-1</n> and <n>PU . 1</n> , and that the 3' site is essential for expression of a <n>luciferase reporter gene</n> driven by the <n>GL alpha promoter</n> .
92366561485>The mean total white cell count increased from a baseline of 11 . 3 x 10 ( 9 ) / L ( SD 2 . 3 ) to 16 . 2 x 10 ( 9 ) / L ( SD 4 . 6 ) on day 1 , normalising thereafter .
105687286533>The level of <n>serum creatine kinase</n> was significantly high 2 days after ESWIB , but it recovered in a week .
37346414400>The results show that nerve and roots differ considerably both in the force they sustain before failure and in the other biomechanics they exhibit .
113761655954><n>FLP</n> and <n>Cre recombinase</n> function in Xenopus embryos .
98130935811>We detected no effect of deleting <n>YCL024W</n> , either alone or in combination with deletion of <n>GIN4</n> .
11006283778><n>Recombinant AROM-p64</n> displayed high binding to single-stranded DNA and poly ( A ) homopolymers suggesting that this protein could play a role in mRNA maturation / metabolism .
82804762009>In our studies , we utilized HIV-1 <n>HXB2</n> and HIV-1 <n>Z2Z6 core enhancers</n> because the Z2Z6 strain has a single point mutation flanking the right <n>ETS-binding site</n> .
14986074225>Four short nucleotide sequences ( <n>boxes I to IV</n> ) contribute to the light responsiveness of the <n>parsley chalcone synthase promoter</n> .
8627667669><n>ZEBRA</n> and cellular <n>AP-1 bZip activators</n> , such as <n>c-Fos</n> , have homologous DNA-binding domains , and their DNA-binding specificities overlap .
82756188256>Drug effect , measured as postural sway , was also similar in the patients with cirrhosis and control subjects ; therefore the ratio of effect area under the curve to concentration area under the curve , a measure of sensitivity , did not differ significantly between the patients with cirrhosis and the control subjects .
89559288915>Damage to the BBB was judged by extravasation of Evans Blue ( EB ) dye , which was administered either 2 , 3 , 24 or 48 h after onset of MCAo .
23358156094>At the carboxyl terminus , deletion as far as residue 388 did not affect in vitro <n>TRF . C</n> assembly , although trans-activating activity was abolished .
118117437687>The procedure facilitated the retention of a mandibular molar with a Class III FI in a manner acceptable to both the patient and the clinician .
68408036634>Histological signs of the flare-up reaction were already present at 6 hr after i . v . challenge and lasted for at least 4 days .
81724168142>Moxidectin ( at 3 times the therapeutic dose ) did not have deleterious effects on cow reproductive performance as examined ( eg , at folliculogenesis , ovulation , and the early embryonic phase of development ) .
11384225529>To this end , an expression cassette consisting of the gene for a <n>green fluorescent protein</n> ( <n>GFP</n> ) flanked at its 3' end by EAV-specific transcription-regulating sequences was constructed .
91999322831>Promoter recognition algorithms identified divergent promoter elements within the CpG island , which lies between the <n>ATM</n> and <n>E14 / NPAT genes</n> , and provide evidence for a putative second <n>ATM promoter</n> located within intron 3 , immediately upstream of the first coding exon .
75462567417>A retrospective epidemiological study is reported concerning burn injuries in 775 children hospitalized at the unit of burn care of Casablanca between 1985 and 1993 .
108510898691>Thus , <n>SAG</n> appears to control cell cycle progression in yeast by promoting ubiquitination and degradation of cell cycle regulatory proteins .
10478275316>The main issues are the need to explain a number of still unknown mechanisms , to determine which "natural diet" carries the minimum coronary risk and whether "new" foods produced by modern technology are really needed to contrast this epidemic .
98875449884>BACKGROUND : Diazepam , one of the benzodiazepine group of tranquilizers , is used as an adjunctive drug for sedation and for relief of anxiety in the treatment of epilepsy .
74137811933>Hippocampal stimulation overlapping conditioned stimulus preexposure produced attenuation of latent inhibition , as did stimulation presented during conditioning after preexposure .
86364287839>Taken together , our results indicate that thrombin-stimulated vascular smooth muscle proliferation is delayed and requires the de novo expression of one or more autocrine mitogens .
90034622179>However , five new mutation sites ( <n>S61</n> , <n>SL1</n> , <n>S29</n> , <n>SL11</n> , <n>SL196</n> and <n>SL126</n> ) are unique to the <n>nrdB</n> intron and disrupt self-splicing .
90117444543>The murine chromosomal locations of the five <n>NMDA receptor channel subunits</n> , the <n>epsilon 1</n> ( <n>Grin2a</n> ) , <n>epsilon 2</n> ( <n>Grin2b</n> ) , <n>epsilon 3</n> ( <n>Grin2c</n> ) , <n>epsilon 4</n> ( <n>Grin2d</n> ) and <n>zeta 1</n> ( <n>Grinl</n> ) subunits , were determined using an interspecific backcross mapping panel derived from crosses of [ ( C57BL / 6JxM . spretus ) F1xC57BL / 6J ] mice .
90290915721>Surprisingly , however , TCR-mediated tyrosine phosphorylation of <n>phospholipase C gamma 1</n> remains intact in the Jurkat cells expressing the <n>A2 / HCP</n> chimera .
71741227927><n>Serum creatine kinase</n> ( <n>SCK</n> ) was measured in ten subjects in the laboratory before and after the performance of bicycle ergometry and a lifting task .
95823266042>N . , and Fanning , E .
18747524627>This indicates that under certain experimental conditions <n>cdc2 / p58</n> and <n>cdc2 / p62</n> may express some differences in their catalytic activity .
49924785294><n>Plasma histaminase</n> in patients of bronchial asthma and the effect of prednisolone administration on it .
31106925776>40 . 3 + / - 10 . 1 mg / l ( SD ) vs 31 . 2 + / - 8 . 0 , P less than 0 . 01 ) . beta 2m was not significantly higher in patients with bone cysts ( 37 . 7 + / - 11 . 4 mg / l vs 37 . 0 + / - 10 . 0 ) , but median duration of dialysis was significantly ( P less than 0 . 01 ) longer in patients with bone cysts ( 90 vs 57 months ) . <n>beta 2m</n> was lower in patients maintained on dialysis for less than 1 year and whose residual urine volume was greater than 0 . 1 litre per day .
114276111301>The susceptibility of Aspergillus fumigatus to mulundocandin , an echinocandin-like compound , and other antifungal agents was assessed by the National Committee for Clinical Laboratory Standards ( NCCLS ) M38-P method , a 2 , 3-bis ( 2-methoxy-4-nitro-5-sulfophenyl ) -5- [ ( phenyl-amino ) carbonyl ] -2H-tetrazolium hydroxide ( XTT ) -based colorimetric assay , and determination of morphologic alterations by microscopy .
2007045633>The authors report a case in which stereotactic irrigation of a brain cyst was temporally associated with respiratory distress .
98836399877>Number of patients infected with nontuberculous mycobacteria ( NTM ) is increasing world-wide in recent years .
112974193270>An <n>F222W : W21F rGST A1-1 double mutant</n> provides a direct fluorescence probe of changes in the environment of the C-terminal residue .
106846605274>Comparison of the <n>plant nuclear tRNA 3' processing enzyme</n> with the plant mitochondrial one suggests that both activities are different enzymes .
81063255329><n>DtxR</n> is an iron-dependent sequence-specific DNA-binding protein that binds to the <n>tox operator</n> , an inverted-repeat nucleotide sequence located upstream from the <n>diphtheria toxin gene</n> .
81664024637><n>Cerebral125 albumin</n> was increased to similar proportions in those groups submitted to hyperosmolality .
13391257479>Laboratory studies using Ca45 labeled teeth and biologically stained teeth confirmed that the dentifrice did not decalcify enamel or bleach teeth .
34667304167>Autonomic dysfunctions were restricted to tonic pupils .
85242927511>Results from the mechanism study have revealed that <n>YY1</n> is able to inhibit transactivation mediated by either <n>AP1</n> or the <n>Sp1-related protein</n> , and <n>YY1</n> suppressive activity is DNA binding dependent .
86225968594>The men self-selected a prescribed diet at home emphasizing saturated fat as the visible fat for 1 week .
93059447638>By analyzing the <n>RanGAP</n> activity of a series of recombinantly expressed <n>rna1p mutant</n> derivatives , we show that the highly acidic sequence in the C-terminal domain of both yeast proteins is indispensable for activating Ran-mediated GTP hydrolysis .
17389365952>One patients had <n>plasma C-peptide</n> greater than 3 pM and was therefore excluded from analysis .
83212035084><n>NF-kappa B p65</n>1 , <n>p50</n> , and <n>Rel</n> functionally synergize with <n>C / EBP alpha</n> , <n>C / EBP beta</n> , and <n>C / EBP delta</n> .
4507605002>Cryoglobulinemia in Raynaud's syndrome .
64334421399>Freezing of plasma to obtain better yield of <n>factor VIII</n> : C .
77590944530>A polymorphic dinucleotide ( GT / CA ) n repeat contained in the NHE5 cosmid was identified and developed into a microsatellite PCR marker .
8902641297>In the VA-SMV mode , the connection was made with valved conduits from the LV apex ( inflow ) to the ascending aorta ( outflow ) ( n = 11 ) or to the DAo ( n = 12 ) .
89710095170>To circumvent this problem , a simple two-step strategy was devised by which essential cis-acting sites like the a sequence can be readily deleted from their natural loci in large viral DNA genomes .
10509768339>The reduction in saturated fatty acids intake led to modest ( but in group 1 significant ) 0 . 15 mmol / l ( 2 . 5% ) reduction in total serum cholesterol level .
110168504227>We cloned a DNA fragment encoding the N-terminal part of a protein with significant similarity to members of the <n>LysR family of transcriptional regulators</n> ( <n>LTTRs</n> ) .
68055376576>Advances in hemophilia treatment : a hepatitis-safe <n>factor VIII</n> concentrate .
11196581036>The records from 1948 through 1967 of 344 previously untreated patients with squamous cell carcinoma of the oral cavity , oropharynx , supraglottic larynx and hypopharynx who had clinically positive cervical lymph node metastases staged N1 , N2A , or N2B , and whose initial neck treatment consisted of external radiation therapy alone were reviewed .
98084419782>A comparative analysis of the reported MOCT-associated malignant melanomas emphasizes the singularity of our case in the amelanotic character of the melanoma , its lymphotropism and the coexistence of invasive squamous cell carcinoma .
85163086684>The remaining <n>RAD+</n> cells progressed to form microcolonies ( < 30 cells ) containing aberrantly shaped inviable cells .
32391063930>Increasing the phosphorus content of the diet improved the reabsorption of calcium and magnesium .
85448208451>Characterization of an <n>EcR / USP heterodimer target site</n> that mediates ecdysone responsiveness of the <n>Drosophila Lsp-2 gene</n> .
73970662449>Drug inhibition of whole blood <n>aspirin esterase</n> .
34033134099>The actuarial local control rates at 10 years for the three treatment groups were as follows : subtotal excision alone , 18% ; subtotal excision plus postoperative radiation therapy , 82% ; and total excision alone , 77% .
98803272338>It is related to a variety of mammalian Golgi-associated proteins and to the yeast <n>Uso1p</n> , an essential protein involved in docking of endoplasmic reticulum-derived vesicles to the cis-Golgi .
118850531777>We found three out of four original ( Volkan's ) groups of linking objects , but also an additional one , hitherto undescribed , comprising objects used for designing a memorial shrine to the deceased .
89741357476>To examine whether thiamine ( vitamin B1 ) deficiency is associated with recurrent aphthous stomatitis , we studied vitamin B1 levels in 70 patients with recurrent aphthous stomatitis and in 50 members of a control group .
17377897384>The upstream delta-alpha breakpoint is flanked by the direct repeats of the acceptor splice site , whereas the down-stream alpha-delta breakpoint is located in the adjacent intron .
78917089895>Like <n>Epo</n> , <n>HNF-4</n> is expressed in kidney , liver , and Hep3B cells but not in HeLa cells .
79597606396>The centromeric YAC contig , which consists of 23 overlapping YACs and orders 19 sequence-tagged sites ( STSs ) , covers a minimum of 2 . 2 Mb and spans the Ewing sarcoma breakpoint . <n>c-ets 1</n> and <n>Fli-1</n> , two members of the <n>ets family</n> , have been linked within 400 kb of intervening DNA within this contig , which also comprises a polymorphic microsatellite , <n>D11S912 ( CA ) n</n> , which we have localized within the <n>Fli-1 gene</n> .
104716965186>Null alleles of <n>SAS4</n> and <n>SAS5</n> bypassed the role of the <n>Abf1p binding site</n> of the <n>HMR-E silencer</n> but not the role of the <n>ACS</n> or <n>Rap1p binding site</n> .
35633998013>For signal durations less than 10 ms , however , the SoNo and S pi No threshold functions converged and the masking-level difference decreased .
90283084003>The initial patients treated with AZQ and mitroxantrone experienced prolonged bone marrow suppression and , therefore , subsequent cohorts were treated with <n>G-CSF</n> , 5 micrograms / kg , beginning the day after completion of the third cycle of chemotherapy .
79887302720>The basal promoter strength of constructs that contained deletions in the <n>U5 region</n> of the <n>LTR</n> was analyzed by <n>chloramphenicol acetyltransferase</n> ( <n>CAT</n> ) assays following transfection of HeLa cells or Jurkat T-cells in the presence or absence of viral transactivator <n>tax</n> protein .
91351492149>In Schizosaccharomyces pombe , the activity of the M-phase-inducing <n>Cdc2 / Cdc13 cyclin-dependent kinase</n> is inhibited by <n>Wee1</n> and <n>Mik1 tyrosine</n>1 <n>kinases</n>1 , and activated by <n>Cdc25</n> and <n>Pyp3 tyrosine</n>1 <n>phosphatases</n>1 .
91719696579>Measurement of the time constant of VO2 and oxygen pulse during constant work rate exercise are useful for the objective evaluation of the training effect of patients with COPD .
35086984670>By order of decreasing rate , finger flexors , jaw , crossed adductors , and triceps reflexes were less frequently elicited in both groups .
62094996022>The direct effects of transmitter release were ( a ) an early fall in MAP followed by a late pressor effect ; and ( b ) an early bradycardia followed by a late tachycardia .
13092559589>66 : 469-479 , 1992 ) .
16018693096>A 724-bp segment of the 5'-flanking region consisting of the proximal E-box flanked upstream by a mammalian-specific 352-bp region was sufficient for maximal transcriptional activation in postconfluent BC3H1 myoblasts .
73477285242>Arachnoid cyst .
45186245008><n>Glutathione peroxidase</n> in human red cells in health and disease .
21131742520>It encodes a protein with three zinc fingers similar to those of the <n>transcription factor Sp1</n> .
92230422029>Liver regional blood volume ( LRBV ) is altered by several disease states and various drugs .
94878417823>The ESEM differs from conventional SEM in that no sample preparation is needed , eliminating artifactual changes .
79354727807>Enhancers containing disrupted <n>Ets-1 binding sites</n> were tested in transient expression assays in the murine T-cell line EL4 . E1 ; alterations in the <n>LVb element</n> affected constitutive enhancer activity , while mutation of either the <n>LVb</n> or <n>LVc element</n> disrupted phorbol ester-induced enhancer activity .
111617933920>The presence of truncated receptor isoforms in diverse species suggests that these proteins may have important functional roles in regulating <n>EGFR</n> activity .
68806506677>The results confirm and extend previous work by other researchers .
27353645130>In the final model , grade ( p = 0 . 0002 ) , peritoneal cytologic results ( p = 0 . 0002 ) , <n>progesterone receptor</n> status ( p = 0 . 004 ) , and age as a continuous variable ( p = 0 . 008 ) were most closely associated with disease-free survival .
28321495289>The lack of change in the ratio of the two spliced products expressed from either the normal or the <n>5'-rearranged myb</n> further indicates that the insertion of the unique 121 amino acids in the larger <n>myb transcripts</n> is not a consequence of tumor-specific activation of the <n>mouse myb oncogene</n> .
14576953464>Removal of <n>beta 2-microglobulin</n> by hemodialysis and hemofiltration : a four year follow up .
13288544931>A single <n>MEF-2 site</n> is a major positive regulatory element required for transcription of the muscle-specific subunit of the <n>human phosphoglycerate mutase gene</n> in skeletal and cardiac muscle cells .
67211886496>The statistical analysis consist of the F test followed by Snedecor 's contrast test .
113829481225>In conclusion , USPIO-enhanced MRI data were capable to characterize tumor microvessel properties in this breast cancer model : microvascular permeability ( determined using USPIO ) correlated significantly with tumor grade .
92611551075>Furthermore , the <n>PH</n> and PTB domains are highly homologous ( at least 40% identical ) to those found in <n>insulin receptor substrates 1 , 2 , and 3</n> ( <n>IRS-1</n> , <n>IRS-2</n> , and <n>IRS-3</n> ) .
11236583644>The authors describe the technique of transverse axial tomography of the spine and give a detailed description of the axial anatomy of the normal lumbar spine from L-4 to the sacrum .
9130595559>Here we report the cloning of the protein that binds to <n>enhancer site III</n> .
113589623672><n>Foxp1</n> and <n>Foxp2</n> are expressed at high levels in the lung as early as E12 . 5 of mouse development with <n>Foxp2</n> expression restricted to the airway epithelium .
74492537327>In the unclipped group arterial pressure decreased 50 mmHg to normal by 24 h and was associated with increased diuresis and a small decrease in blood volume ( 9 . 8% ) .
92303849258>The mean times to detection of all mycobacteria with BACTEC 9000 MB and BACTEC 460 TB were similar ( 10 . 3 and 10 . 0 days , respectively ) .
17178332829>The <n>alpha inhibin promoter</n> containing a mutated <n>CRE</n> was not regulated by forskolin in granulosa cells and did not bind the <n>CREB protein</n> .
21761524920>We show also that RA represses the transcriptional activity of a reporter gene containing a <n>TPA</n> responding <n>AP1 binding site</n> driving the <n>HSV tk promoter</n> .
82236134652>We also compared the sequence with the partly homologous products of the S . cerevisiae genes <n>TPS2</n> and <n>TSL1</n> which code for the larger subunits of the <n>trehalose synthase complex</n> and with a <n>TSL1 homologue</n> , <n>TPS3</n> , of unknown function .
32079758798>Seventy-two hours after administration of vitamin K1 , plasma concentrations of the vitamin were not different from normal .
101926383162>Methanesulfonyl fluoride ( MSF ) : a double-blind , placebo-controlled study of safety and efficacy in the treatment of senile dementia of the Alzheimer type .
16172424498>FDA regulations for <n>growth factors</n> and related products .
109133046569>Six distinct <n>Ets mRNAs</n> were identified : <n>Ets2</n> , <n>Fli1</n> , <n>GABPalpha</n> , <n>SAP1</n> , <n>Elk1</n> , and <n>PE1</n> .
93227389141>The histidine-tagged gene , <n>rpoCHIS</n> , was used to replace the wild-type allele in the chromosome of S . coelicolor and S . lividans .
104007949221>Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to <n>latent membrane proteins 1 and 2A of Epstein-Barr virus</n> .
216275493>To identify these sites , the deduced amino acid sequence of the 3T3-L1 <n>adipocyte insulin receptor</n> of the mouse was determined .
98521362634><n>Wild type HA-p190</n> induced a phenotype of rounded cells with long , beaded extensions similar to that seen when <n>Rho</n> function is disrupted by ADP-ribosylation .
92888485119>Following 2 . 5 Gy , <n>HbO2</n> changes were minimal .
91620971753>In summary , the data establish that the previously reported <n>human MAdCAM-1 cDNA</n> does indeed encode the human homologue of <n>mouse MAdCAM-1</n> , despite gross dissimilarities in the <n>MAdCAM-1</n> C-terminal structures .
85504621317>Upstream of the <n>dra gene</n> an open reading frame of 313 amino acids was identified .
10468033310>Chemical uptake into human stratum corneum in vivo from volatile and non-volatile solvents .
94120799368>Diet therapy with soy proteins for chronic stomach ulcers .
14731962088>This may result in more reabsorption and hence reduced renal clearance .
4204609055>In patients who had received no previous drug treatment , log baseline <n>plasma renin</n> activity and change in mean blood pressure after SQ 20881 correlated significantly ( r = 0 . 651 , P less than 0 . 05 ) .
82533874086>We conclude that sequences outside of the <n>hLEF HMG box</n> mediate cell- and context-specific activation of the <n>TCR alpha enhancer</n> and may facilitate interactions between <n>hLEF</n> and other T-cell-specific factors recruited to the enhancer .
26686916053>More mRNA corresponding to <n>nagB</n> and <n>nagA</n> is detected than that corresponding to the distal genes , <n>nagC</n> and <n>nagD</n> .
106523242717>However , its participation in <n>collagen</n> binding has not been shown .
35869254250>Development of a provisional information-retrieval descriptor language for "Roentgenology and Medical Radiology" for use in the Medinform system .
80209653685>The sequenced genomic region thus accounts for essentially all of the longest known transcript ( 4 . 5 kb ) , although the precise ends of this transcript have not been defined .
25186453169>Neonatal Chagas disease : laboratory diagnosis during the first year of life .
84563788411>This study evaluates the feasibility of indirect mesenteric lymphangiography as a colonoscopic technique in a canine model .
111583374110>The gonadotrope-specific and regulated expression of the <n>GnRH receptor</n> ( <n>GnRH-R</n> ) gene is dependent on multiple transcription factors that interact with the <n>noncanonical GnRH-R activating sequence</n> ( <n>GRAS</n> ) , the <n>activator protein-1</n> ( <n>AP-1</n> ) element , and the <n>steroidogenic factor-1</n> ( <n>SF-1</n> ) binding site .
89466682622>FK506 is 10- to 100-fold more potent than cyclosporin A in preventing organ rejection and in toxicity .
8760889805>Comparison of the deduced amino acid sequences with protein sequences of T . pyriformis <n>H2As</n> showed only two and three differences respectively , in a total of 137 amino acids for <n>H2A1</n> , and 132 amino acids for <n>H2A2</n> , indicating the two genes arose before the divergence of these two species .
112593471093>Anecdotal observations scattered throughout the literature have often provided clues to underlying variations in humans' ability to handle dietary chemicals .
104389416951>Fewer recombination events are detected in four different B and T cell lines that do not undergo switch recombination of their endogenous genes .
104987178425>These observations establish that <n>RsmC</n> negatively regulates <n>rsmB</n> transcription but positively affects <n>RsmA</n> production .
33598604047>The relations among various negative emotional and behavioral characteristics ( e . g . , aggression , anxiety , undercompliance , depressive mood ) and adjustment were examined through use of data from the 31-year-old New York Longitudinal Study .
113357106862>This was most pronounced during the initial phase of <n>Erk</n> activation .
15626595719>Institution of both intravenous and intracisternal administration of amphotericin B and possibly concomitant intravenous administration of dexamethasone may be warranted in situations in which the association of C . immitis with CNS vasculitis or encephalitis appears likely before serologic or cultural confirmation of C . immitis infection involving the CNS is available .
18939272513>Increasing mean arterial pressure by phenylephrine infusion to levels much greater than produced by NMA and NNA caused only small reductions in cardiac output .
88962721398>The nucleotide sequence of 22 , 846 bp of the left arm of chromosome IV is described .
23298402977>The application of these microelectrodes to the measurement of rapid , transient changes in retinal [ K+ ] o is presented .
13910017011>From all clinically important yeasts species , a total of 96% were identified by ATB method according to conventional methods .
111567897159>To account for this observation , other possible causes include increased CSF pulsation in children creating motion artifact , changes in arterial oxygen concentration intrinsic to propofol or related to the supplemental oxygen normally administered , or changes in CSF protein levels related to propofol binding to proteins for uptake into CSF .
2390146634>A gas-liquid chromatographic method for the determination of p-chlorophenoxyisobutyric ( CPIB ) acid in blood plasma is described .
1002933718>The fatigue exercise showed relatively high blood lactate concentration [ 12 . 5 ( SD 2 . 6 ) mmol x l ( -1 ) ] and an increase of <n>serum creatine kinase</n> ( <n>CK</n> ) activity delayed by 2 days [ 540 ( SD 407 ) U x l ( -1 ) ] .
10823630628>However , the presence of effacement seems to be a more reliable and practical parameter that will be preferred in that prediction .
111522835644>We have investigated the role of <n>NGF</n> in regulating gene transcription in PC12 and INS-1 cells , in order to define if there are NGF-regulated genes per se .
87769017093><n>Chloroplast mutator</n> ( <n>chm</n> ) of Arabidopsis is a recessive nuclear mutation that causes green and white variegation in leaves and is inherited in a non-Mendelian fashion .
6445396253>In three of the seven , inhalation of 2 ml normal saline produced FEV1 falls of 25% to 30% , but these falls were not as great as each subject's reactions to the test solutions .
92611849599>As demonstrated by gel mobility shift analysis and supershift experiments , <n>FIRE1</n> , located between -516 and -498 , is responsible for binding <n>NF-Y</n> .
36935434357>The less-polar mycolic acid-containing Rhodococcus species showed chromatographic patterns that partially overlapped ( in elution times ) the patterns of Nocardia asteroides , N . otitidiscaviarum , and N . brasiliensis , but the larger number of peaks in the last species made separation between the genera possible .
107418503271><n>Electrophile Response Elements</n> ( <n>EpREs</n> ) , located in 5'-flanking sequences of both the <n>GCSh</n> and <n>GCSl subunit genes</n> , are hypothesized to at least partially mediate gene induction following xenobiotic exposure .
106751544254>Extreme potency of <n>botulinum toxin</n> .
73943641244>It appears that the pulmonary gas exchange parenchyma of these smallest mammals is well suited to supply the organism with the comparatively high levels of O2 required by the high metabolic rates , exhibiting a structural adaptation of the lung to higher VO2 .
64532906258>The development and histostructural organization of intrahepatic biliary ducts were studied on a human embryofetal material 6 to 32 weeks old .
13286816257>Labile <n>LTR-binding proteins</n> appear to be essential for <n>c-myc</n> hyperexpression , since both LTR-enhanced transcription and the activities of <n>LTR-binding proteins</n> are specifically decreased after inhibition of protein synthesis ( A .
20174141814>Age at POI and asymptote were achieved later for Line RBC2 than for Line F .
42263604863>Disorders of platelet function in chronic myeloid leukemias .
75081407390><n>Hepatitis B surface antigen</n> was detected in 2 patients , with negative <n>hepatitis C virus antibody</n> .
50286285327>Clinical and angiographic examinations in occlusion disease of the great intestinal arteries .
10870391684>Prevention , differential diagnosis and therapy of travel diarrhea .
96492656004>CONCLUSIONS : Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate performed in a single office visit represent a cost-effective biopsy strategy for men presenting with an abnormal digital rectal examination and / or elevated <n>serum PSA</n> .
11140472986>We compare the results of this algorithm with the results obtained with two other algorithms , the optimal algorithm for monochannel nonoverlapping noise and the optimal algorithm for multichannel additive noise , and we show that in both cases improvement can be obtained .
96961649676>A safe and simple system for the detection of sudden infant death syndrome ( SIDS ) is proposed .
10764760787>Transactivation of naturally occurring HIV-1 long terminal repeats by the <n>JNK</n> signaling pathway .
30662085089>Histological examination revealed a small simple renal cyst associated with renal cell carcinoma .
29942533145>Those dosages that inhibited mean <n>NTE</n> activity in spinal cord greater than or equal to 72% and brain greater than or equal to 66% of control values within 44 hr postexposure produced marked spinal cord pathology 14 days postexposure in greater than or equal to 90% of similarly dosed animals .
98100879787>RESULTS : An herpetic seroconversion is observed with presence of type I herpes simplex virus ( HSV I ) nucleic acids in the recipient's aqueous humor .
6694380748>Plasma NE was also low in the anephric group ( 289 mg / liter + / - 126 ( 1 SD ) vs 612 + / - 189 , P = 0 . 033 , resting ) . ( ABSTRACT TRUNCATED AT 250 WORDS )
15889135183>A gene homologous to the <n>Escherichia coli dnaA gene</n> was isolated from Pseudomonas putida and its transcription was investigated in E . coli as well as in P . putida .
107562256816>CONCLUSION : More than 50% of patients with perennial rhinitis and CRS do not improve after surgery , a response that may be predicted by more cells expressing <n>IL-5 mRNA</n> in the ethmoid sinuses .
59691855849>Concussion of the spinal cord .
16987619978>Relatively large DNA rearrangements spanning the region with tandem direct repeats encoding the <n>carboxy-terminal histone H1-like structure</n> of <n>AlgP</n> were detected in several strains upon conversion from the mucoid to the nonmucoid phenotype .
85667516241>This approach places <n>gHoxb-1</n> into the normal embryonic spatiotemporal context in which lab acts .
94231232384>IVOX was named as an acronym for intravascular oxygenator .
97703782928><n>EGFR</n> levels were found to be elevated 5- , 3 .
9882334214>However , serial passages of fetal lamb kidney ( FLK ) cells , which are sensitive to infection with BLV , after transient transfection revealed that mutation of a second tyrosine residue in the N-terminal motif completely prevented the propagation of the virus .
6037831528>Serum levels of <n>IgG</n> and <n>IgM</n> were also raised , but contrary to the findings of other observers <n>IgA</n> levels were normal .
9703205546>The performance of three commonly used chemical cartridge respirators for SO2 was measured under working conditions in a copper smelter .
89851229529>The promoter region ( P1 ) corresponding to the main group of transcription initiation sites is devoid of TATA and CAAT boxes but has putative binding sites for the <n>transcription factor SP1</n> and is embedded in a large G + C-rich domain of a CpG island , features shared by the promoters of constitutively expressed housekeeping genes .
113088511138>We find that our response function is well approximated by the GSER only within a particular frequency range determined by the material parameters of both the bead and the network .
93178309284>THE SCALING OF SONG FREQUENCY IN CICADAS .
27111453385>HIV infectiousness and the AIDS epidemic .
78761946832>Endocytosis and lysosomal targeting of <n>epidermal growth factor receptors</n> are mediated by distinct sequences independent of the <n>tyrosine kinase domain</n> .
10429184463><n>Expansins</n> are a family of proteins that catalyse long-term extension of isolated plant cell walls due to an as yet unknown biochemical mechanism .
115173993913>The patterns of early mRNA and protein expression in these seven mutants were examined , and it was found that mutation of the <n>T' ( 135 ) acceptor site</n> resulted in the utilization of cryptic splice sites and the generation of new <n>T' species</n> .
44682644979>Problems common to pediatrics and anesthesiology .
912143053><n>Shc</n> stimulates <n>Ras / mitogen-activated protein kinase</n> ( <n>MAPK</n> ) through forming a complex with <n>Grb2</n> at the phosphorylated tyrosine ( Y ) residue 317 .
75906577490>Cholangiography was performed in all cases and classified by a scoring system specifically developed for pediatric patients .
63360454466>Frog type I ( Ft I ) and frog type II ( Ft II ) slowly adapting ( SA ) units produced spikes only at the indentation phase , and the threshold response phase ( TRP ) , i . e . . the phase of the first spike was for ca .
105854402612>We describe here a <n>Drosophila melanogaster FAK homologue</n> , <n>DFak56</n> , which maps to band 56D on the right arm of the second chromosome .
106176135847>Chem .
101030022201>A single N-glycosylation site present in <n>chicken gp42</n> is conserved among all five of these proteins : carbohydrate analysis of <n>gp42</n> revealed the presence of a complex type glycan chain at this site .
18141827387>Different doses of 15-methyl-PGF2 alpha ( 0 . 125-10 mg ) were used to induce luteolysis and oestrus in 7 heifers with 28 treatments on day 8-12 of the oestrous cycle .
74757937365>BSE and farmworkers .
31447058394>The distribution of the sites of recombinational resolution is inversely correlated with that of the gradient of sequence divergence , with only approximately 7% of the X recombinants resolved within the 3' third of the X blocks where two diverged <n>Alu family repeats</n> reside .
92309457613>A pre-boutonniere deformity was simulated by dividing the central slip .
106886463042>First , human erythroid K562 cells stably integrated with various <n>HS-40 mutants</n> cis linked to a <n>human alpha-globin promoter-growth hormone hybrid gene</n> were analyzed by genomic footprinting and expression analysis .
73068397170>Electron microscopic picture of the cerebral cortex in rats cooled to 22 degrees C .
88911318841>Enterococcus faecium strains with vanA-mediated glycopeptide resistance were isolated by enrichment culture from the intestines and feces of several animal species , mainly horses and dogs ( 8% positive ) , chickens ( 7% positive ) , and pigs ( 6% positive ) .
62549739404>Poly ( dT ) and denatured calf thymus DNA were more effective than were other polynucleotides tested in promoting accumulation of 19 <n>HDP*</n> ; ( dT ) 8 was as effective as were longer molecules of ( dT ) n , but ( dT ) 4 and ( dT ) 6 were much less effective , indicating that the binding site involved in 19 <n>HDP*</n> accumulation covered between 6 and 8 residues of ( dT ) n .
59090345819>Studies on powdered preparations .
41646695829>Ultraviolet light-induced <n>kinin</n> formation in human skin .
61528445975>Effect of bromazepam on <n>growth hormone</n> and <n>prolactin</n> secretion in normal subjects .
16557137040>In this study , we have cloned a region that complements the exoenzyme S-deficient phenotype of strain 388 <n>exs1</n> : : <n>Tn1</n> , a <n>chromosomal Tn1 insertional mutation</n> .
10584138408>Cytoprotection with amifostine in radiotherapy or radio-chemotherapy of head and neck tumors .
98728329513>The BAL concentrations of the nine cytokines evaluated for the more and less affected lungs were compared : <n>interleukin-6</n> ( <n>IL-6</n> ) , <n>IL-8</n> , <n>IL-12</n> , <n>tumor necrosis factor-alpha</n> ( <n>TNF-alpha</n> ) , and <n>interferon gamma</n> ( <n>IFN-gamma</n> ) showed significant differences ( p ranged between 0 .
19180733836>Comparison of the cDNA-predicted <n>avian TnIcardiac amino acid sequences</n> with known <n>TnI sequences</n> indicated 1 ) that the presence of an N-terminal extension sequence carrying a dual <n>protein kinase A</n> phosphorylation target site and an adjacent proline-rich segment is an ancient cardiac-specific feature of <n>TnI</n> which has been conserved since the bird / mammal divergence , 2 ) that features of the near-N-terminal <n>troponin C</n> ( <n>TnC</n> ) -binding site sequence suggest isoform-specific adaptation of <n>TnI</n> and <n>TnC</n> , and 3 ) that the avian <n>TnIcardiac</n> internal <n>actin / TnC-binding , actomyosin-inhibitory , domain</n> shows significant sequence divergence from <n>mammalian TnIcardiac sequences</n> , including the absence of a <n>protein kinase C</n> target site which is a cardiac-specific feature of <n>TnI</n> in mammals .
81381806978>Certain <n>spt10</n> spontaneous alleles are good suppressors but have a normal growth rate , suggesting that the <n>SPT10 protein</n> may have two distinct functions .
109728941539>Genomic libraries were stored as frozen cultures in a 96-well format , each well containing approximately 300-600 colonies ( 12 plates for small library , four for medium-size library and four for large library ) .
85435958529>In summary , the efficacies of adjuvant carboplatin and of abdominal radiotherapy seem to be identical .
108252937828>Immobilized dimers of <n>N-cadherin-Fc chimera</n> mimic cadherin-mediated cell contact formation : contribution of both outside-in and inside-out signals .
13149537153>In contrast , gel mobility shift experiments have failed to reveal that <n>HAP2</n> or <n>HAP3</n> binds to domain 1 or that <n>hap3</n> mutations affect the complexes bound to it .
95159241719>The <n>PDH complex-encoding genes</n> were identified by hybridization experiments and sequence analysis in two separate gene regions in the genome of Z . mobilis .
95832019530>None of the patients was obese .
40190668484>Sensory evoked field potentials were recorded from the mesencephalic reticular formation ( MRF ) , central gray ( CG ) and somatosensory cortex ( SCX ) , following incremental doses of halothane in freely-moving rats .
109838575656>Mucosal application of NCX-4016 , however , did not cause PD reduction and luminal H+ loss , but produced a marked hyperemia , resulting in no damage in the stomach of both normal and STZ-diabetic rats .
77982172558>A role for <n>glycogen synthase kinase-3</n> in the control of gene expression .
98684128597>CONCLUSION : Our study shows that ( 1 ) total body BMD and femoral neck BMD were significantly higher in the study group that performed weight-bearing exercises than in control subjects , ( 2 ) swimming exercise had no effect on BMD , and ( 3 ) although swimming is not a bone-building exercise , it can significantly improve shoulder , back , and grip muscle strength .
11127955970>Adjuvant therapy for colon cancer Surgery alone may fail to cure a considerable number of locally advanced colon cancers .
89524836213>Several particular features of this polypeptide fragment from the <n>hamster lysyl-tRNA synthetase</n> suggest that it is implicated in the assembly of that enzyme within the multisynthetase complex .
107927187628>Identification of an <n>AfsA homologue</n> ( <n>BarX</n> ) from Streptomyces virginiae as a pleiotropic regulator controlling autoregulator biosynthesis , virginiamycin biosynthesis and virginiamycin M1 resistance .
87566091475>The deduced amino acid sequence was highly conserved across the wide range of eukaryotes ( vertebrates , invertebrates , fungi , plants and protozoa ) in which this gene has now been identified .
111494723032>We observed <n>NP / NMP4 / CIZ</n> expression in osteocytes , osteoblasts , and chondrocytes in rat bone .
1829460992>Southwestern blot analysis demonstrated that this phosphoprotein can bind the <n>kappa B element</n> directly and specifically .
82688333570>The therapeutic action of cyclosporin A ( Sandimmun ) : its application in rheumatoid arthritis .
39404264601>Results of this study indicate that GLC of short chain fatty acids produced on agar medium by anaerobes , combined with simple tests such as Gram's stain and colonial morphology , may allow fir direct presumptive genus identification from an initial pure agar culture .
96427646082>Moreover , the mass estimated with the QCM response through the Sauerbrey equation and the mass which can be measured thanks to other analytical techniques , in our case an enzymatic assay , are different : the deposited mass is generally overestimated by the QCM .
107289863502>The <n>Wnt</n> signaling pathway functions reiteratively during animal development to control cell fate decisions .
46767345089>The relationship of human umbilical arterial and venous plasma levels of corticosteroids to gestational age .
105361258091>Oseltamivir ( GS4104 ) , which can be administered orally , is the prodrug of GS4071 , a potent and selective inhibitor of <n>influenzavirus neuraminidases</n> .
9515858330>BACKGROUND : <n>Defensins</n> , also known as <n>human neutrophil peptides</n> , are antimicrobial peptides present in the azurophil granules of neutrophils .
93882462888>We also show by immunogold electron microscopy immunocytochemistry that <n>amphiphysin I</n> is localized in the nerve terminal cytomatrix and is partially associated with endocytic intermediates .
85303427173>The <n>human gp39 promoter</n> .
11488681372>The metabolic clearance rate of progesterone was 295 + / - 49 ( S . E . ) 1 / day .
89709844476>The <n>SCMV SNE sites</n> contain potential overlapping core recognition binding motifs for <n>SRF</n> , <n>Rel / NFkappaB</n> , <n>ETS</n> , and <n>YY1 class transcription factors</n> but fail to respond to either serum or <n>tumor necrosis factor alpha</n> .
43850606516>Disulfiram and the drug-induced effects on motility .
94140749370>Resistance training shifts the power curve in a positive direction when the measurements are determined with absolute loads , but the increased power may not be transferred to an absolute performance task like the SSP .
11859569378>The authors concluded that ultrasonic Doppler-cardiography can be used for measuring the relative changes in the stroke volume .
15493466920>The <n>c-Ets-1 oncoprotein</n> is a transcription activator that specifically binds to DNA .
6339096128>Internally oriented patients' scores on Rotter's Internal-External Locus of Control Scale remained the same over treatment but those of externally oriented patients shifted toward greater internal control .
89103734562>Percent identities of the <n>mouse PP2</n> to <n>mouse Y1</n> , <n>mouse Y4 / PP1</n> and <n>human Y2 receptors</n> are 53 , 42 , and 31 , respectively .
106675972119><n>ZK7</n> and <n>HZF16 genes</n> appear to be the splice variants transcribed from the same gene .
41645954829>Evidence for two distinctive clinical , epidemiological , and immunological types of infection .
91591609030>Positional cloning has already produced the sequences of more than 70 human genes associated with specific diseases .
75594788053>15 , 2500-2508 ; O'Neill , T .
50310745331>Serum lipid changes during pregnancy due to oral calcium administration .
112666153602>The protein is composed of two major domains separated by a hydrophobic linker region of 20 amino acid residues .
81317469313><n>MEK</n> itself is activated via serine phosphorylation by <n>upstream activator kinases</n> , including <n>c-raf</n> , <n>mos</n> and <n>MEK kinase</n> .
110719246405>A protein lacking the <n>SH2</n> and RING finger domains has no activity , but a chimeric protein with the <n>SH2</n> and RING finger domains of <n>SLI-1</n> replaced by the equivalent domains of <n>c-Cbl</n> has activity .
100950614656>Sequence analysis revealed that the <n>MEMA protein</n> is identical with a <n>160 kDa nuclear 'domain rich in serines' ( DRS ) protein</n> occurring free in the nucleoplasm and in <n>U2-ribonucleoprotein structures</n> .
80559393646>The central globular domain is highly similar to those regions from other <n>H1 molecules</n> , and the carboxyl-terminal domain contains a repeating hexapeptide motif , variants of which are conserved among <n>H1 molecules</n> .
60987195925>Neither side effect nor abnormal laboratory findings due to this drug were observed .
30027863725>One group ( n = 9 ) was premedicated with midazolam , 0 . 1 mg kg-1 , and atropine 0 . 2-0 . 4 mg i . m .
20613337435>No evidence for the presence of introns within the <n>acvA gene</n> has been found .
23727122217>The effects of tap ( TW ) or carbonated ( CW ) water on arterial pH , partial pressure of carbon dioxide ( PCO2 ) and plasma lactate were determined in heat-stressed broilers .
84385848899>Weak promoter activity was observed for the promoter of the <n>C1 and C2 ORFs</n> ( <n>C1-C2 gene</n> ) and for the promoter of the <n>V1 ORF</n> .
16999442991>These results strongly suggested that similar , if not identical , the <n>CArG box binding proteins</n> interact with the functionally different promoter element in the <n>VLC1</n> , <n>cardiac alpha-actin</n> , and <n>c-fos genes</n> .
8771781257>The <n>ORFII gene product</n> is targeted to the chloroplast , which is consistent with previous data indicating the presence of <n>PMSR</n> activity in the chloroplast .
107176122864>BACKGROUND : The aim of this study was to determine the response rates and toxicity of two regimens containing <n>granulocyte-macrophage-colony stimulating factor</n> ( <n>GM-CSF</n> ) in combination with <n>interleukin-2</n> ( <n>IL-2</n> ) in the treatment of patients with metastatic renal cell carcinoma .
107482042290>( 1998 ) J .
40014134661>For this purpose , a simple respiration-control device has been developed that enables the patient to monitor breath-holding during successive scans .
113556151206>Additional education and research is needed to provide further direction for intervention and incorporation into practice .
112676794006>The <n>438 bp EcoRI fragment</n> , which was detected by Southern hybridization , reveals an open reading frame which encodes a protein of 103 amino acids .
113791061216>In the meantime , one has succeeded to establish the deammonification processes in a continuous flow moving-bed pilot plant .
62861916077>Restoration of impaired immune functions in aging animals .
110111394021>While this Saccharomyces cerevisiae <n>SIN4 gene product</n> is a component of a mediator complex associated with <n>RNA polymerase II</n> , various studies suggest the involvement of <n>Sin4</n> in the alteration of higher-order chromatin structure .
79722379818>A high-resolution restriction map of over 200 kb of contiguous DNA containing <n>N-myc</n> has been generated by subcloning YACs into cosmids .
8442384128>While the latter corresponded to a protein of 824 amino acids , an upstream open reading frame ( uORF ) within the 5' leader could potentially encode a 54 amino acid peptide .
10445161290>In summary , the no-adverse-effect-level for this study was determined to be 1000 ppm , based on decreased weight gain in female rats , and on slight organ weight changes in both sexes at 3000 ppm .
86508188608>A secondary spread of an imported methicillin-resistant Staphylococcus aureus strain ( MRSA ) to two other patients occurred within a Danish surgical ward in spite of isolation of a multitraumatized index-patient immediately after arrival from a hospital in the Mediterranean area .
94853084391>The FMN moiety but not the [ 3Fe-4S ] cluster of the subunit appears to participate in this reaction .
93518239632>It thus appears that <n>MAPK</n> functions in meiotic maturation by preventing unfertilized eggs from proceeding into parthenogenetic development .
108601315027>Tolterodine users were 7 . 5 times more likely to have received another spasmolytic drug ( RR 7 . 5 , 95% CI 4 . 8 to 11 . 9 ) .
42460545843>Effect of immune lymphocytes and of <n>rabbit-anti-lymphocyte globulin</n> ( <n>RAMLG</n> ) on infected macrophages exposed to increased incubation temperature in vitro .
108572158082>The Menopause-Rating-Scale ( MRS I ) was used in clinical practice since 1992 .
92787588719>CONCLUSION : Patients wit clinically palpable neck disease ( N1-3 ) , histological evidence of metastatic nodal disease , extracapsular spread , and three or more positive lymph nodes are at greater risk of developing failure at distant sites .
29198323630>Cardiac disease was not detected with M-mode , 2-dimensional real-time or pulsed-wave Doppler echocardiography .
111271619904>Bupropion to aid smoking cessation .
40051906003>One extract with the lowest PCA content was non-carcinogenic .
91010854785>The derivatives of the latter two cell lines showed increased expression of the <n>p27Kip1 protein</n> and inhibition of cell growth .
81966168807>Interestingly , the interaction of <n>ZAP-70</n> with the motif was dependent on the presence of both <n>ZAP-70 SH2</n>1 <n>domains</n>1 and both of the tyrosine residues in the motif , suggesting that <n>ZAP-70</n> interacts with two phosphotyrosine residues and that the binding of the two <n>SH2 domains</n> is cooperative .
81889788162>The baroreflex latency ( from the ECG R-wave to the integrated MSNA burst peak ) was constant at approximately 1 . 20 s during sleep , suggesting that pulse-synchronicity was maintained .
119020689263>One CKD patient's journey .
10764970576>The mode of resistance to quinupristin / dalfopristin was not evident ( sat A-negative by PCR ) ; and these cases illustrate the existence of streptogramin-resistant isolates before the introduction of this antimicrobial class into human clinical practice .
89805362700>The conservation of both the G-box and H-box in different <n>CHS promoters</n> emphasizes their importance as regulatory motifs .
114159581283>In the past decade , there have been enormous advances in the use of Bayesian methodology for analysis of epidemiologic data , and there are now many practical advantages to the Bayesian approach .
96420428442>Binding affinities of different nucleotide mono- , di- and triphosphates and non-hydrolyzable analogs indicate that the beta-phosphate moiety is required for substrate binding .
80839639342>The LTR-binding activities of <n>VBP</n> , <n>a1 / EBP</n> , and B-cell nuclear extract protein were compared and mapped by gel shift , <n>DNase I</n> footprinting , and methylation interference assays .
88146518794>The importance of temporal factors on the presence and severity of ethanol withdrawal signs in the rat was quantified using rating scale , tremor , and acoustic startle paradigms .
10602838432>In this study 26 patients ( 20 females and 6 males ) were evaluated .
80536978043>BACKGROUND AND DESIGN : Fifty-nine melanocytic nevi with eccentric foci of hyperpigmentation ( "small dark dots" ) that measured primarily 1 to 2 mm in diameter were prospectively examined to determine the histologic correlates of the dark dots .
97603415368>Phosphocreatine hydrolysis during submaximal exercise : the effect of FIO2 .
28781003582>Present results reveal a frequency-dependent inhibition of ganglionic transmission by diltiazem , and suggest that diltiazem may depress excessive sympathetic activity without affecting normal ganglionic transmission .
29478661961>Thus , quantitative analysis of thallium-201 uptake and washout provided objective evidence for improved myocardial perfusion after coronary angioplasty .
82895936581>However , artificially ventilated rats , pretreated with MK-801 , were more sensitive ( lethal cocaine dose , 76 . 6 + / - 8 . 0 mg / kg , n = 5 ) than vehicle pretreated rats ( 129 . 4 + / - 15 . 8 mg / kg , n = 6 ) , indicating that MK-801 may increase both the respiratory and the cardiac toxicity of cocaine in urethane anesthetized rats .
21070733736>However , overexpression of both the <n>STE4</n> and <n>STE18 proteins</n> did not generate a stronger pheromone response than overexpression of <n>STE4</n> in the presence of wild-type levels of <n>STE18</n> .
109034958156>In a gel retardation assay using HepG2 nuclear extracts , the 5' flanking sequence from -74 to -46 showed a shifted band .
103926692972>In an attempt to reduce the incidence of NSAID-induced gastrointestinal lesions , the following approaches have been proposed : ( i ) use of the prostaglandin analogue misoprostol , which is an antiulcer drug which has been proven to be as effective in the prevention of NSAID-induced gastric and duodenal ulcers as in the reduction of serious upper gastrointestinal complications ; ( ii ) <n>histamine H2 receptor</n> antagonists ( H2 antagonists ) , e . g . ranitidine , cimetidine and famotidine , which are useful in the prevention of NSAID-induced duodenal ulcers during long term treatment , but not in the prevention of NSAID-induced gastric ulcers ; ( iii ) proton pump inhibitors , e . g omeprazole , and pantoprazole , whose efficacy in preventing NSAID-associated ulcers has been recently demonstrated ; and ( iv ) barrier agents , e . g . sucralfate , which cannot be recommended as prophylactic agents to prevent NSAID-induced gastropathy .
97926274743><n>SRC-1</n> can relieve the NF-kappaB-mediated repression of <n>GR</n> activity .
106907259591>Two other patients underwent PRFR .
84193186891>Biol .
34010604096>Thin melanomas can metastasize and be lethal .
109038438383>The chromosomal localization on distal chromosome 7 places it in a cluster of imprinted genes , flanked by the previously described <n>Tapa1</n> and <n>Kcnq1 genes</n> .
94479624482>Consistent with this interpretation , a mutant form of <n>XRN1</n> , which encodes a 5'-3' exonuclease , was identified as an extragenic suppressor that increases the half-life of <n>rhis4 mRNA</n> , leading to a 10-fold increase in steady-state mRNA levels compared to the <n>wild-type HIS4 mRNA</n> level .
18857522501>Chlamydia trachomatis and Chlamydia psittaci were not affected by methanol fixation .
114519953426>Topological and Mutational Analysis of <n>Saccharomyces cerevisiae Ste14p</n> , Founding Member of the <n>Isoprenylcysteine Carboxyl Methyltransferase Family</n> .
80211756038>The <n>pexB upstream region</n> contained 245 nucleotides within which sequences approximating the consensus for <n>cyclic AMP receptor protein</n> and <n>integration host factor binding sites</n> were discernible .
79665837212>Transient transfections of a construct expressing the RNA transcript defined by clone B1 . 1 into D17 cells led to the expression of an <n>Env / Mlvi-4 fusion protein</n> with an apparent molecular mass of 33 kDa .
114083381272>This study suggests that PSP is more common than previously considered , is commonly misdiagnosed and that the majority of cases are not initially referred to neurologists .
90832916173>While <n>TGF-beta1</n> does not alter the mitogen-induced expression and abundance of G1 phase <n>cyclin D1</n> and <n>cdks 4 and 2</n> in MCs , it inhibits <n>cyclin E-cdk 2</n> activity , thus preventing mitogen-elicited phosphorylation and inactivation of <n>pRb</n> in G1 phase and transition to S phase .
113927729963>The application of the biotechnology at the plants for treatment of the surface storm waters from the industrial zone Telychka of the city of Kyiv has allowed the content of petroleum in water dropped to the Dnieper to be constantly reduced 50-100 times .
24847146123>Structural organization and expression of the <n>mouse estrogen receptor</n> .
29896377623>These data suggest that dopaminergic regulation of adrenal zona glomerulosa corticosteroid and <n>renal renin</n> secretion is absent in patients with high spinal cord transections , suggesting that intact neural pathways from the central nervous system are necessary for metoclopramide stimulation of aldosterone and <n>renin</n> secretion in men .
77526447717>Thus , VF resistant to defibrillation is not necessarily associated with both toxic plasma drug level and remarkably decreased conduction .
118381021706>Wegener's granulomatosis
24377925050>Comparison of <n>elastase-1</n> with <n>amylase</n> , <n>lipase</n> , and trypsin-like immunoreactivity in the diagnosis of acute pancreatitis .
111796892930>The <n>Sox gene family</n> ( <n>Sry</n> like <n>HMG box gene</n> ) is characterised by a conserved DNA sequence encoding a domain of approximately 80 amino acids which is responsible for sequence specific DNA binding .
92655349600>The dose was 50 Gy / 20 fractions / 5 weeks .
110294678778><n>Vasoactive intestinal peptide</n> and <n>pituitary adenylate cyclase-activating polypeptide</n> inhibit <n>nuclear factor-kappa B-dependent gene</n> activation at multiple levels in the human monocytic cell line THP-1 .
22068581604>Homozygous <n>protein C</n> ( <n>PC</n> ) deficiency is reported in two siblings ( girl and boy ) who received their proper diagnoses at the ages of 7 4 / 12 and 1 3 / 12 years respectively .
88100408089>A subsequent screen for the loss of the positively selectable target locus marker detects the desired replacement at modest frequency ( > 2% ) .
11353774359>Here we report the isolation and characterization of the <n>forkhead homologue in rhabdomyosarcoma</n> ( <n>FKHR</n> ) , a recently described member of the <n>hepatocyte nuclear factor 3 / forkhead homeotic gene</n> family , as a <n>nuclear hormone receptor</n> ( <n>NR</n> ) intermediary protein .
22878602944>Ultrastructural and morphometric study of the myeloid parenchyma cells of mice prior and after X-ray exposure .
80293347945>Cloning of <n>higher plant omega-3 fatty acid desaturases</n> .
94887253405>To determine the true molecular identity of <n>SFD</n> , both the 50- and 57-kDa polypeptides were directly sequenced .
70150186793>Synchronous extracts showed no significant migration inhibition in allogeneic assays .
94773167284>In order to decipher the pathway that leads to <n>Hox gene</n> induction , we have investigated whether a <n>Hox gene</n> regulator , the leucine zipper transcription factor <n>MafB / Kr</n> , is itself transcriptionally regulated by the environmental signals .
87260248705>Eight cats infected with H . pylori were used in the study .
65168476307>However , subcutaneously administered pneumococci gave a lower mortality than pneumococci given intravenously or intraperitoneally .
95579122630>Their mean IOP was 15 . 3 ( SD 3 . 7 ) mmHg prior to induction of anesthesia , 13 . 5 ( SD 3 . 5 ) mmHg after loss of eyelash reflex following injection of methohexitone , 16 . 1 ( SD 2 . 4 ) mmHg after cessation of muscle fasciculations induced by suxamethonium , 19 . 2 ( SD 5 . 6 ) mmHg after cessation of convulsion and 15 . 5 ( SD 4 . 4 ) mmHg following resumption of regular spontaneous respiration .
8164684485>The ligand for <n>RXR</n> , 9-cis retinoic acid , has the opposite effect of destabilizing the heterodimeric-DNA complex .
92593136905>The majority of <n>PI kinase</n> activity appeared to be cbl-associated after <n>PRL</n> stimulation .
1004797051>Current world literature .
84064978523>Defects of <n>fibrillin</n> ( <n>FBN1</n> ) , a glycoprotein component of the extracellular microfibril , cause Marfan syndrome .
107481757288>The substrates for glycan synthesis in the lumen of the Golgi are nucleotide sugars that must be transported from the cytosol by specific membrane-bound transporters .
110838686939>DNA binding and <n>glutathione S-transferase</n> pull-down assays demonstrate that binding requires <n>Elk-1 ( 1-212 )</n> but not the C-terminal transactivation domain .
91264871632>( 1994 , Hum .
106275189543>The synergistic effect due to the 5'-3' cooperation was at least fourfold greater than the sum of the contributions of the individual UTRs .
6212776406>At Cabras ( Oristano ) , a town characterized by a high incidence of thalassaemia and <n>G6PD</n> deficiency less than half the people between 18 and 35 have a fair knowledge of genetic diseases and of their prevention .
74957266139>These motifs include a <n>Chi motif</n> and a <n>Chi-like element</n> previously found in the recombination hotspot region of the <n>Bcl-2 proto-oncogene</n> and close to chromosomal breakpoints in T-ALL lines .
97719859761>16 subjects were repatch tested to ethylmercury chloride ( EtHgCl ) and to solutions containing EtHgCl mixed with L-cysteine and glutathione , respectively .
37215945301>Adhesion , phagocytosis , chemotactic and random migration , nitroblue tetrazolium dye reduction of peritoneal exudate neutrophils and macrophages , <n>fibrinogen</n> level , gelation of soluble <n>fibrin</n> and serial dilution protamine sulfate test were investigated in 115 New Zealand white rabbits with experimentally induced Shwartzman phenomenon in the colon , and in control animals .
72626257103>Corticosteroid therapy is known to be hazardous in patients with occult infection but the mechanism by which the host parasite relationship is altered by steroids is not known . We have used an intestinal protozoal parasite , Giardia muris , to examine the effects of corticosteroids on the number of parasites in the intestine in the course of a primary infection .
102020069423>Each recombinant product was a fusion protein with a <n>B domain</n> of <n>Staphylococcal protein A</n> ( <n>SPA</n> ) .
17110412224>The <n>C5 alpha-chain</n> was encoded by 49 kilobases containing 26 exons ; the beta-chain was encoded by 29 kilobases containing 16 exons .
92432673480>METHODS : Four hundred fifty patients with the diagnosis of squamous cell carcinoma of the oral cavity received their primary treatment at Roswell Park Cancer Center ( RPCI ) from 1971 to 1991 .
26318873302>Eighty patients presenting to HGGM with non-Hodgkin's lymphomas between 1962 and 1986 , were reviewed .
89188855274>In contrast , <n>dig1 dig2</n>1 cells constitutively invade agar medium , whereas a <n>dig1 dig2</n>1 <n>ste12</n> triple mutant does not , indicating that <n>Dig1</n> and <n>Dig2</n> share a role in negatively regulating the invasive growth pathway .
98497229837>During presentation of happy facial expressions , we detected a signal increase predominantly in the left anterior cingulate gyrus , bilateral posterior cingulate gyri , medial frontal cortex and right supramarginal gyrus , brain regions previously implicated in visuospatial and emotion processing tasks .
16525152254>In contrast to behavioral deviation ( the avoidance conditioning lost ) , the haloperidol intrastriatal microinjections did not affect the DA synaptic level in rostral neostriatum .
74767017544>Considerably high levels of <n>IgE antibodies</n> was also established while other pollens did not show such correspondence .
9400613882>Coexpression of mouse <n>PKR ( 1-515 ) WT</n> as a <n>Gal4</n> DNA-binding domain fusion with either the catalytic-deficient human <n>PKR ( 1-551 )</n> K296R mutant , the RNA-binding-deficient human <n>PKR ( 1-551 ) K64E / K296R</n> double mutant , or wild-type mouse <n>PKR ( 1-515 ) WT</n> as full-length <n>PKR-Gal4</n> activation domain fusions resulted in activation of the <n>HIS3</n> and <n>lacZ</n> reporters .
101877983178>Overexpression of either <n>DAP-1</n> or <n>sentrin</n> causes apoptosis of TNF-sensitive L929 fibroblast cell line , as well as TNF-resistant osteosarcoma cell line , U2OS .
95729904830>An association between <n>hSIE</n> and <n>Stat-3</n> after <n>MHC-I</n> ligation was directly demonstrated by precipitating <n>Stat-3</n> from nuclear extracts with biotinylated <n>hSIE</n> probe and avidin-coupled agarose .
9136239189>The mechanism by which large molecules , such as the diphosphonate 99mTc-labeled EHDP or 99mTc-labeled pyrophosphate , pass through capillaries in bone is by passive diffusion .
25384506635>We have isolated cDNA clones from rat brain and human liver encoding a putative isoform of the <n>Na , K-ATPase beta subunit</n> .
57632875710>I .
110126801716><n>Src</n> activation induced by <n>FGF1</n> was blocked by the <n>SH2 domain</n> of <n>Src</n> and <n>PP2</n> , a specific inhibitor of <n>Src</n> .
87345388720>In a third experiment , crossover AM between dissimilar textures was investigated , and it was found that the more salient textures carried the AM .
24898953146>Muscle action potential and masticatory rhythm of anterior temporal and masseter muscles in children and adults .
47126265108>Chemical constituents of the gentianaceae V : tetraoxygenated xanthones of Swertia chirata Buch . -Ham .
93034373684>However , although deletion of <n>Fp1</n> in the <n>hCRBP1 gene</n> yielded increased <n>CAT</n> activity , pointing toward a negative regulatory function exerted by this element , its insertion upstream of the <n>p12 basal promoter</n> results in an impressive positive stimulation of <n>CAT gene</n> expression .
84668647614>Mutational analyses have demonstrated the importance of sequences within the 327 bp segment that contain a putative <n>cyclic AMP responsive element binding protein</n> ( <n>CREB</n> ) binding site for <n>TGF-beta 1</n> and PMA responsiveness and putative <n>PU-1</n> and <n>Sp1 binding sites</n> for basal promoter activity .
82709858245>Response durations were short .
112037024225>Thus , <n>Xlim-1</n> not only contains a unique tyrosine-rich activation domain but also contains a negative regulatory domain in <n>CT239-403</n> , suggesting a complex regulatory mechanism underlying the transcriptional activity of <n>Xlim-1</n> in the organizer .
17357215726>The predicted amino acid sequence exhibited 70% identity to that of <n>Bacillus stearothermophilus TyrTS</n> and 55% identity to that of <n>E . coli TyrTS</n> , while identity to a second cryptic <n>B . subtilis TyrTS gene</n> , designated <n>tyrZ</n> , was only 27% .
27481883440>Behaviorally , a pain-tolerant group ( PT = 29 Ss ) tolerated the entire 3-min test ( means = 180 + / - 0 sec ) , while a pain-sensitive group ( PS = 13 Ss ) averaged only 50 . 31 + / - 20 . 81 sec of the cold-pressor test ( t = 16 . 75 , P less than 0 . 0001 ) , replicating our earlier studies .
86286814051>Sequence conservation is greatest for residues located near the active centers of the <n>exo</n> and <n>pol domains</n> of the <n>E . coli DNA polymerase I</n> structure .
84311008385>This study compared the gross and fine motor performance of 14 traumatically brain-injured children ( five to 15 years old , with loss of consciousness for at least 24 hours ) to 14 normal children group matched for age and sex .
84418692594>The plateau MO2 value was that predicted by allometric relation .
72975767161>One was allowed fresh drinking water ad libitum whilst the other received Aludrox in their drinking water .
9428799488>Although the gene is substantially smaller than the human genes for other mitochondrial enzymes , its intron / exon organization is very similar , especially to that of <n>P450scc</n> .
97511668898>This and previous results suggest that the <n>CRE</n> and <n>Sp1 site</n> may synergistically activate <n>TH</n> transcription in a promoter context-dependent manner .
33522544040>The same rhythmic structure enables a prediction to be made concerning when vowels of stressed syllables will be auditorily perceived .
81279501728>In order to evaluate the function of the hypothalamic-pituitary-thyroid ( HPT ) -axis in unipolar depression , the authors measured basal 0800h plasma levels of free thyroxine ( FT4 ) , free triiodothyronine ( FT3 ) , and <n>thyroid stimulating hormone</n> ( <n>TSH</n> ) by means of the new , ultrasensitive assays ( TSH-IRMA ) in 69 healthy controls , 62 minor , 101 simple major , and 57 melancholic depressed subjects .
81147104149>We have previously shown that <n>LBP-1</n> represses HIV-1 transcription by inhibiting the binding of <n>TFIID</n> to the TATA box .
11045180887>Leptinaemia does not correlate with the actual or mean blood pressure reading nor with stage of hypertension according to the WHO classification .
107675538537><n>Hex</n> is expressed in the developing liver coincident with the <n>forkhead / winged helix transcription factor</n> , <n>Hepatocyte Nuclear Factor 3beta</n> ( <n>HNF3beta</n> ) .
15699458836>The <n>SEN1 gene</n> corresponds to a 6 , 336-bp open reading frame coding for a 2 , 112-amino-acid protein ( molecular mass , 239 kDa ) .
97018214065>In contrast , transcription initiating from <n>opuE P-1</n> ( <n>sigma A</n> ) rose in proportion to the external osmolarity and was maintained at high levels .
1901946880>A synthetic oligonucleotide containing the <n>SRE sequence</n> from the <n>mouse c-fos gene promoter</n> ( -299 to -322 ) was radioactively labeled , used as a probe for the mobility shift assay and Southwestern ( DNA-protein ) blotting , and also used for sequence-specific affinity chromatography .
88868455379>As extensively examined with the <n>myogenin promoter</n> , presence of one or multiple copies of <n>Me</n> in the vectors elevated the expression activity in myotubes by 4 . 5- to 19-fold over those without <n>Me</n> , but not significantly in myoblasts .
17107664708>The proteins differ in the presence or absence of a 21-amino-acid sequence located 24 amino acids C terminal of the translational initiation codon .
82070225263>Subunit composition and domain structure of the <n>Spo0A sporulation transcription factor of Bacillus subtilis</n> .
114354284060><n>Cytosolic acetyl-CoA synthetase</n> ( <n>AceCS1</n> ) activates acetate to supply the cells with acetyl-CoA for lipid synthesis .
10936920756>Previous experience and contextual cues are essential elements in the generation of a subjective prediction .
18992092519>Increases in the perfusate PCO2 but not in the perfusate H+ were highly correlated with decreases in both myocardial contractility and oxygen consumption ( r2 = . 88 ) .
92857156291>Although previous data have suggested that <n>Rev</n> uses the same export pathway as <n>uracil-rich small nuclear RNAs</n> and <n>5S ribosomal RNA</n> , the <n>CTE</n> seems to interact with evolutionarily conserved factors that are essential for cellular mRNA export .
84325263689>These exons were identified by cloning and sequencing cDNAs obtained by <n>polymerase</n> chain reaction amplification of a fibroblast cDNA library .
75305492479>Analysis of the sequences with the BLAST and GRAIL programs provided additional independent evidence that 15 of these 17 clones contain coding sequences and that nine other clones are likely to contain sequences coding for portions of new genes .
59944219195>Consanguinity and migration in the marriages of the region of Nunoa , Santiago , 1850-1960 .
98473973760>Approximately 50% of the residues are conserved among all three sequences , yet all three viruses have retained response elements for glucocorticoids , two positionally conserved CCAAT boxes , and positionally conserved TATA boxes .
23200087944><n>TMBr-1</n> is identical to <n>striated muscle alpha-tropomyosin</n> from amino acids 1 through 258 but contains a novel COOH-terminal region from amino acids 259 through 281 .
34864058938>Most of the prepeptide portion of the precursor polypeptide is encoded by the next three exons , and the mature form of <n>IL-1 alpha</n> is encoded by the remaining three exons .
89143886181>The assessment using 7 H 9 liquid medium by the former author demonstrated the potent activities of both CS-940* and sparfloxacin ( SPFX ) , followed by AM-1155* , ciprofloxacin ( CPFX ) , levofloxacin ( LVFX ) , OPC-17116* , NM-394* in sequence .
94987698693>Its expression pattern is representative of many B cell-specific proteins , which are essential for B cell development and activation but are down-regulated after B cells become terminally differentiated plasma cells .
89770139954>The implications for estimates of cortical magnification and possible differences in the specializations of foveal and peripheral vision are discussed .
20621161089>Pargyline , a <n>monoamine oxidase</n> inhibitor , reduces peak 3 transiently ( max .
108057294581>The stoichiometry of the complexes formed with the <n>dodeca-satellite C strand</n> suggests that , in <n>DDP1</n> , the 15 consecutive <n>KH domains</n> are organized such that they define two nucleic acid binding surfaces .
105523576262>CONCLUSIONS : In addition to the superiority of octafluoropropane-filled microspheres to air-filled microspheres for LV opacification , the efficacy of OCTA is relatively unaffected by impaired LV function and is less susceptible to the effects of poor echogenicity than AIR .
93056314654>Overexpression of <n>BAG-1</n> also protected certain cell lines from heat shock-induced cell death .
103301596872>Thus , <n>VDR</n> acts selectively on the two components required for activation of this promoter / enhancer : it competes with <n>NFAT1</n> for binding to the composite site , positioning itself adjacent to <n>Jun-Fos</n> on the DNA .
104696565449>The nucleosomal response associated with <n>immediate-early gene</n> induction is mediated via alternative <n>MAP kinase cascades</n> : <n>MSK1</n> as a potential <n>histone H3 / HMG-14 kinase</n> .
112218365411>More importantly , this fusion converted a less effective vaccine into one with significant potency against established E7-expressing metastatic tumors .
85904657924>Its organization and regulation indicate that the <n>S . pombe URA1 gene product</n> appears very similar to the <n>S . cerevisiae URA2 gene product</n> .
100228674808>Elimination of <n>ETH1</n> in <n>apn1</n> strains also increased spontaneous mutation rates 9- or 31-fold compared to the wild type as determined by reversion to adenine or lysine prototrophy , respectively .
92714173766>The <n>MCAD nuclear receptor response element 1</n> ( <n>NRRE-1</n> ) interacts in vitro with <n>ERR alpha</n> expressed in COS-7 cells .
39408185860>Fulminant hepatitis A in chronic HBV carrier .
11331604144><n>Srb10</n> is a physiological regulator of <n>Gcn4</n> stability because both phosphorylation and turnover of <n>Gcn4</n> are diminished in <n>srb10 mutants</n> .
86433828115>An apparent N-terminal transit peptide in the coding region and a 3' poly ( A ) tail exist in the cDNA clone indicated that this chloroplast protein as nuclear encoded .
13704463788>These sites are also potential keratan sulfate attachment sites .
12590271893>The concept of "structural identifiability" is employed in this analysis to determine which model parameters can be and which cannot be determined "uniquely" from given input-output data ; a step-by-step procedure based on an extension of this concept is presented for adapting the overall approach to the experimental design problem .
28291834061>DNA sequence analysis revealed that these clones encode two distinct forms of <n>translocase</n> .
10684534502><n>Protamine</n> and heparin doses , their sum ( Sigma-dose ) and differential ( Delta-dose ) doses , and activated clotting times were tabulated .
78776199121>In addition , we found that cell-specific suppression of RA-stimulated <n>zif268 gene</n> expression can be attributed to a 29 base pair nucleotide sequence , located downstream of the <n>RA-responsive region</n> in the <n>zif268 gene</n> .
7806492107>This structure of <n>cucumisin</n> suggests that it is probably synthesized as an inactive precursor .
57223415669>Identification and estimation of monosaccharides and disaccharides in urine by gas-liquid chromatography .
100213505087>In the current model , <n>Wingless / Wnt</n> signal stabilizes <n>Armadillo / beta-catenin</n> , which then accumulates in nuclei and binds <n>TCF / LEF family proteins</n> , forming bipartite transcription factors which activate transcription of <n>Wingless / Wnt responsive genes</n> .
112589064730>In DNA strand exchange reactions using oligonucleotides , we found that <n>Rec2</n> exhibited a pairing bias that is opposite that of <n>RecA</n> .
109438916582>The ability of <n>U6-U57 mutants</n> to influence the fidelity of both branch site and 3' splice site recognition suggests that this nucleotide may participate in the formation of the active site ( s ) of the spliceosome .
69776056160><n>Endorphins</n> and legal issues .
113186085189>Human brain cDNA library screening and 5' rapid amplification of cDNA ends yielded <n>full-length DENTT cDNA</n> containing an 1899-bp open reading frame encoding a predicted 633-amino-acid protein with four potential nuclear localization signals ( NLSs ) and two coiled-coil regions .
119076911816>The orientations of the contact surfaces and their locations relative to the object's center of mass were varied .
97744446726>The carboxyl-terminal portion of <n>UKLF</n> contains three zinc fingers of the Cys2-His2 type and binds in vitro to the <n>CACCC motif</n> of the <n>beta-globin promoter</n> and to the <n>Sp1 recognition sequence</n> .
9931769928>Since <n>myoglobin</n> is co-extracted with the <n>hemoglobin</n> , the 2 heme pigments are separated in one portion of the extract by precipitating the <n>hemoglobin</n> in an 85% ( NH4 ) 2SO4 solution .
112416724065>Cloning and characterization of the <n>murine beta ( 3 ) integrin gene</n> promoter : identification of an <n>interleukin-4 responsive element</n> and regulation by <n>STAT-6</n> .
92889161852>Polarised expression of human intestinal <n>N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase</n> ( <n>human meprin</n> ) alpha and beta subunits in Madin-Darby canine kidney cells .
15021579981><n>ME1a1</n> , a 16-base-pair nuclear factor binding site residing between the <n>c-MYC P1 and P2 transcription initiation sites</n> , is required for <n>P2</n> activity .
15725494850><n>Protein tyrosine kinases</n> ( <n>PTKs</n> ) are implicated in the control of cell growth by virtue of their frequent appearance as products of retroviral oncogenes , as intracellular signal transducers , and as <n>growth factor receptors</n> or components thereof .
110768609316>Experiments with epitope-tagged proteins show that <n>UEV1A</n> is a nuclear protein , whereas both <n>Kua</n> and <n>Kua-UEV</n> localize to cytoplasmic structures , indicating that the <n>Kua domain</n> determines the cytoplasmic localization of <n>Kua-UEV</n> .
33823101661>Abnormal technetium Tc 99m medronate scans in patients with previously undiagnosed polyarthralgias suggested inflammatory arthropathy and influenced management decisions with favorable therapeutic outcomes .
80485821272>However , regional MVO2 increased to about the same extent in the CFX ( from 6 . 0 + / - 0 . 7 to 12 . 4 + / - 0 . 9 ml O2 . min-1 times 100 g-1 ) and the LAD region ( from 7 . 0 + / - 0 . 6 to 14 . 5 + / - 1 . 3 ml O2 . min-1 times 100 g-1 ) .
40883964557>Among the patients grades 1-2-3 , 81% had a good out come without any neurological abnormality , among the patients graded 4-5 , only 27% had a fair out come .
51100495375>1st data on the immunosuppressive therapy of scleroderma .
68211471108>Sulphur amino acids ( g / 16 g N ) were higher in the isolates than in the flours .
13027652002>These components both had a median R2 of 0 . 84 , compared to median R2s ranging from 0 . 37 to 0 . 83 for five commonly used ad hoc EEG components .
98194118475>By <n>DNase I</n> footprint analysis of the <n>PNR element</n> , a palindrome of two high-affinity <n>Ets-binding sites</n> ( <n>CTTCCCTGGAAG</n> ) was identified .
97084503057>Toxicity during the therapeutic period was not significant in the study group compared with the historical control , treated with the same regimen without <n>G-CSF</n> .
17327362489>Transcripts from a second <n>POU-domain gene</n> , <n>Oct-25</n> , were present at low levels in oocytes and early embryos and were dramatically upregulated during early gastrulation .
25287306818>Moreover , exons 2a and 2b share the same 5' sequence but differ from each other by the use of two distinct donor splice sites 171 bp apart in the gene .
88746319217>Discrimination between HIV-1 and HIV-2 showed evidence for the presence of HIV-1 only .
94350562151>The functional mature domain of <n>pediocin AcH ( Lys+1 to Cys+44 )</n> is targeted into the E . coli sec machinery and secreted to the periplasm in active form when fused in frame to the COOH terminus of the <n>secretory protein maltose-binding protein</n> ( <n>MBP</n> ) .
78831672037>In yeast , the products of the <n>UPF1</n> and <n>UPF3 genes</n> are required for this decay pathway , and in this report we focus on the identification and characterization of additional factors required for rapid decay of nonsense-containing mRNAs .
99401329936>Unified theory of segregated-stack organic charge-transfer solids : Magnetic properties .
76525752046>Furthermore , microinjection of dominant negative forms of <n>Rac</n> and <n>Cdc42</n> or of the <n>Rho</n> inhibitor <n>C3 transferase</n> blocked serum-induced DNA synthesis .
87548525507>In gel retardation assays , an RCS cell-specific protein and another closely related protein expressed only in RCS cells and primary chondrocytes bound to a 10-bp sequence within the 18-mer .
113125841157>Copyright 2001 Academic Press .
112923355366>It is surprising that dnaE173 , a potent mutator mutation specific for sequence substitution as well as single-base frameshift , did not enhance the frequency of the hot-spot frameshift mutation .
18464913953>However , the relative positions of the VV genes ( genus Orthopoxvirus ) are different than those of the corresponding ORFs in SFV ( genus Leporipoxvirus ) , indicating complex rearrangements of DNA in the genome of one or both of these viruses subsequent to their divergence from a common ancestor .
114845781369>CONCLUSION : There are no differences in the measurement data derived from this method and actual measurement data from an object created by the computer-aided dental design program .
89276126425><n>Ki-ras</n> and <n>p53 mutations</n> in pancreatic ductal adenocarcinoma .
38616874527>Eleven healthy , normotensive males undergoing routine restorative dental care were evaluated during treatment for possible hemodynamic alterations in response to potential sympathetic nervous system stimulation .
113697008782>CSR is directed to specific heavy chain isotypes by cytokines and B cell activators that induce transcription from the unrearranged , or germline ( GL ) , C ( H ) region genes .
96284199600>As predicted by the Wing and Kristofferson model , the durations of successive ISIs tended to be negatively correlated .
9802206344>Based on sequence homology , the genes were identified as <n>TEF</n> , encoding <n>translation elongation factor-1 alpha</n> and <n>RPS7</n> , encoding <n>ribosomal protein</n> S7 .
31479126606>Symptomatic hyperventilators had a larger number of sighs and abnormally wide fluctuations in baseline for inspiratory time , expiratory time , and PETCO2 .
96657201520>As the high-affinity Mg2+ binding sites are filled , the primer terminus migrates from the <n>exonuclease site</n> to a highly based stacked <n>polymerase active site</n> .
10503812334>A population pharmacokinetic study of cyclosporin in organ transplant patients , including elderly allograft recipients up to 75 years of age , did not identify age as a covariable influencing cyclosporin pharmacokinetics .
74459717322>The same response occurs whether acrylamide is given immediately after nerve ligation or 1 week later .
82005287513>This strategy was used to place both the <n>Tn903 neo gene</n> and the <n>Rhodosporidium toruloides phenylalanine ammonia lyase</n> ( <n>PAL</n> ) -encoding gene under the transcriptional control of <n>pPGK</n> : : <n>REP2</n> .
47668882591>Early heparin therapy in 60 children with acute meningococcemia .
75080827387>The highest decrease in mutagenic activity was observed when enzymatic bleaching was used together with chlorine .
117235111562>Regarding gestational risk , 3 , 243 drugs used ( 34% ) belonged to category A risk , 1 , 923 ( 22 . 6% ) to category B , 3 , 798 ( 39 . 7% ) to category C , 289 ( 3 . 0% ) to category D , and 55 ( 0 . 6% ) to category X .
80019669805>These same regions showed remarkable homology to two invertebrate proteins , <n>CNC</n> and <n>skin-1</n> , postulated to regulate embryonic development in Drosophila melanogaster and Caenorhabditis elegans , respectively .
66683166418>Using a MOS-Hypersil reversed-phase column with a phosphate buffer--acetonitrile mobile phase , baseline separation of antipyrine , its metabolites 3-hydroxymethylantipyrine , norantipyrine and 4-hydroxyantipyrine , and the internal standard , phenacetin , was achieved within 6 min .
79885591789>The other element bound <n>RBP-J kappa</n> with low affinity .
115282531403>Copyright 2001 S .
36355974310>In addition , on the Cohler's maternal scale , Korean mothers were found to view their infants as more passive and dependent than American mothers did ( P less than 0 . 00 ) .
92350739192>A 2 years and 9 months old female patient , with the diagnosis of Weaver syndrome is reported .
106536972067><n>Actins</n> show two different forms of N-terminal processing dependent on their N-terminal sequence .
36518404188>Ex vivo <n>MAO</n> inhibition data indicated DPGPEA to be an inhibitor of <n>MAO-B</n> , although the effect was much weaker than seen with tranylcypromine or pargyline .
110317736617>For this purpose , the writhing test , capsaicin and formalin induced-pain in mice were used .
66303196369>Brain pH following 3 h of cerebral focal ischemia changed from a normal value of 7 . 0 to 6 . 5 and 6 . 2 in animals studied under barbiturate and halothane anesthesia , respectively .
3178097328>The CHARGE association is a collection of multisystem congenital anomalies including choanal atresia .
109897772516>No specific subgroup of clients benefited more from URD , although a prospective study employing random assignment might be more successful in identifying such a group .
15122595183>Because of this latter phenomenon , we were able to identify a particular cysteine motif that was repeated multiple times in <n>Dfurin2</n> but present only twice in <n>mammalian furin</n> .
23394476438>We have synthesized [ 7 , 7-2H2 ] -19-OHA with high deuterium content and , together with [ 7 , 7-2H2 ] A and [ 9 , 11-2H2 ] estrone ( E1 ) , have developed a quantitative assay of serum level 19-OHA , A , and E1 using the gas chromatography / mass spectrometry-mass fragmentography method to monitor individual subjects throughout pregnancy .
85676831466>The <n>human purH cDNA</n> is 1776 base pairs in length encoding for a 591-amino acid polypeptic ( Mr = 64 , 425 ) .
32354873750>Incorporation of 0 . 1 or 0 . 2 M sodium dihydrogen phosphate in the sugar solutions resulted in a decrease in the shelf-life of diltiazem .
89155089598>Moloney murine leukemia virus ( MMLV ) -derived pUCMoTiN-based retroviral vectors were engineered to allow constitutive and <n>Tat</n> ( <n>trans-activator of transcription</n> ) -inducible expression of five <n>hammerhead ribozymes</n> targeted against highly conserved sequences within the <n>group antigen</n> ( <n>Gag</n> ) , <n>protease</n> ( <n>Pro</n> ) , <n>reverse transcriptase</n> ( <n>RT</n> ) , <n>tat</n> , and <n>envelope</n> ( <n>Env</n> ) coding regions of human immunodeficiency virus type-1 ( HIV-1 ) RNA .
49473475261>Spleen weight in rats during tumour growth and in homograft rejection .
85119945065>We have found out that one-year-old carps are extremely sensitive to ichthiomycin in concentrations between 25-125 micrograms / dm3 .
79371324827>Remarkably , <n>U21</n> contains a long stretch ( 13 nt . ) of complementarity to a highly conserved sequence in <n>28S rRNA</n> .
86431111457>The <n>humanized LL2</n> ( <n>hLL2</n> ) , lacking <n>light chain variable region</n> glycosylation , exhibited immunoreactivities that were comparable to that of <n>chimeric LL2</n> ( <n>cLL2</n> ) , which was shown previously to have antigen-binding properties similar to its murine counterpart , suggesting that the VK-appended oligosaccharides found in <n>mLL2</n> are not necessary for antigen binding .
109559134506>Once HIT II is suspected , heparin ( and low-molecular-weight heparins ) should be stopped immediately .
69539579496>Whereas <n>creatine kinase</n> activity declined exponentially from a single peak , <n>myoglobin</n> appeared in multiple episodes inadequately represented by a single peak value and having no clear clinical correlation .
87548345040>Twelve genomic fragments containing novel response elements are described , and the transcription unit associated with one of them , <n>NN-84AG</n> , was characterized in detail .
100497427532>Analysis of the consensus binding sequence and the DNA-binding domain of <n>ZF5</n> .
79776485481>Sequencing of the <n>TP53 transcripts</n> from exons 2 to 10 , however , did not reveal mutations of the remaining allele in any of these tumors .
45786869475>Pneumothorax following lung abscess in the renal transplant patient .
113362111184>The iterative method proposed by Bengtsson [ Appl .
10878675700>CONCLUSION : The alpha2-adrenergic antagonist idazoxan increases glucose-induced sympathetic activity but not energy expenditure in obese subjects .
21452685128>These losses account for the resistance of EDS-IV <n>collagen</n> to cyanogen bromide and <n>mammalian collagenase</n> digestion .
41010034795>Relations between cellular electrical activity and cardiac mechanical activity in man , the dog and the rabbit .
98609799533>Expression of <n>p130 ( Cas )</n> ( <n>Cas</n> ) , a major binding protein for the <n>Crk SH2-domain</n>1 , also induced <n>JNK</n> activation , which was blocked by the <n>SH2-mutant</n> of <n>Crk</n> .
19343782556><n>Skeletal muscle metaboreceptor</n> responses are impaired in heart failure .
96135746169>The purified recombinant protein was assayed for its enzyme activity by monitoring transfer of [ 3H ] methyl groups from the substrate DNA to the <n>MGMT protein</n> ; the activity was found to be stable at 90 degrees C for at least 30 min .
92873627287>This interaction involved the <n>SH3 region</n> of <n>p50 ( csk )</n> and a proline-rich region ( <n>PPPLPERTPESFVLADM</n> ) outside the catalytic region of <n>PTP-PEST</n> .
86646679550>SETTING--Delhi , urban India , 1985-6 .
81436679507>The mean ( + / - sd ) intra-vesicular pressure ( IVP ) and maximal urethral closure pressures ( MUCP ) were 10 . 3 ( + / - 1 . 7 ) and 129 . 8 ( + / - 19 . 6 ) cmH2O , respectively , and the ratio between MUCP and IVP was 13 . 2 ( + / - 2 . 5 ) .
11565747996>Data from in vitro splicing assays , UV crosslinking and RNA-binding competition experiments indicates a strong correlation between the binding affinities of <n>PSI</n> for the SELEX sequences and their ability to modulate splicing of <n>P element IVS3</n> in vitro .
70782636859>Use of subcutaneous deferoxamine in a child with hemochromatosis associated with congenital dyserythropoietic anemia , type I .
39747907016>The primary CT findings were misinterpreted as a brain infarct or possibly a tumour .
86283024987>If <n>hnRNP K</n> is a transcription factor , then interactions with the <n>RNA polymerase II</n> transcription apparatus are predicted .
110381183731>Methyl formate was used as the solvent of biodegradable oligoesters for the fabrication of microspheres with encapsulated <n>bovine serum albumin</n> ( <n>BSA</n> ) .
9135066196>We report here that constitutively active <n>Mek1</n> could activate <n>p96h2bk</n> in the absence of <n>oncogenic Ras</n> .
1106316984><n>Botulinum toxin A</n> in the treatment of hemiplegic spastic foot drop--clinical and functional outcomes .
86493897790>Mutational analysis of the <n>P2-proximal CTCF binding site</n> and transient-cotransfection experiments demonstrate that <n>CTCF</n> is a transcriptional repressor of the <n>human c-myc gene</n> .
82137477091>To determine whether the excess prevalence of human immunodeficiency virus type 1 ( HIV-1 ) infection in US black and Hispanic homosexual men relative to white men can be explained by differences in sociodemographic factors , history of sexually transmitted diseases , or sexual and drug-use behaviors , the authors conducted a cross-sectional analysis of baseline HIV-1 seroprevalence and HIV-1 risk factors among 4 , 475 non-Hispanic white , 234 Hispanic white , and 194 black homosexual men from four centers in the United States ( Baltimore / Washington , DC , Pittsburgh , Chicago , and Los Angeles ) .
24039261265>Antibodies raised against a bacterially produced <n>beta gal-trk receptor kinase fusion protein</n> recognized a 44 kd phosphoprotein phosphorylated on serine , threonine and tyrosine in extracts of <n>trk-2h</n> transformed NIH3T3 cells .
1027644179>Potscoital test .
84590128429>Fibular dimelia with deficiency of the tibia .
88684731667>Thus , although <n>p28</n> may play only a limited role during the early embryonic cleavages , it may function later in development to establish a somatic type of cell cycle .
21208334393>In Denmark only 1-3 cases of transfusion-associated hepatitis NANB ( TAH-NANB ) are registered annually or about 1 case per 100 , 000 units transfused .
10364425593>These indications of deregulated signalling in the absence of tyrosine 118 were substantiated by sustained activation of <n>STAT3</n> .
110807963240>Interestingly , this mutant cell line lacks expression of the <n>IKK regulatory protein</n> , <n>IKKgamma</n> .
75305022028>Membrane-bound <n>Steel factor</n> induces more persistent <n>tyrosine kinase</n> activation and longer life span of <n>c-kit</n> gene-encoded protein than its soluble form .
28637475022><n>Replacement variant histone genes</n> contain intervening sequences .
9712644610>Transcriptional regulation of the <n>GluR2 gene</n> : neural-specific expression , multiple promoters , and regulatory elements .
72982597164>Determination of lead in blood .
106734263619>The central ( R ) domain is responsible for receptor-binding activity whereas the N-terminal ( T ) domain mediates translocation , the process by which the C-terminal cytotoxic domain is transported from the receptor to the site of its cytotoxicity .
110142138935>To determine whether interaction of arsenite with the hormone-binding domain results in receptor activation , COS-1 cells were transiently cotransfected with the <n>chimeric receptors GAL-ER</n> , which contains the hormone-binding domain of <n>ERalpha</n> and the DNA-binding domain of the transcription factor <n>GAL4</n> , and a GAL4-responsive <n>CAT reporter gene</n> .
113116879259>The JHRLSS has been used in prior studies to assess RLS severity , but has not previously been validated in relation to direct measures of the morbidity associated with RLS .
82043487733>VP-16 , ifosfamide and cisplatin ( VIP ) for extensive small cell lung cancer .
109211975877>Measurements were compared with two computerised treatment planning systems--Theraplan VO5B and ADAC Pinnacle3 V4 . 0b .
108415375803>The experimentally mapped regions of <n>RPB5</n> involved in these interactions correspond to distinct and surface-exposed alpha-helical structures .
10945010766>The role of daunorubicin in induction therapy for adult acute myeloid leukemia .
26454315559>These data suggest that hypocitraturia in type I renal tubular acidosis may be due to a defect in proximal tubule function .
80628243026>Each expressed domain , as well as <n>FKBP-33</n> itself , possesses <n>peptidyl-prolyl cis-trans isomerase</n> activity , though with much lower specific activities than <n>FKBP-12</n> .
56712675635>5- ( Dimethylaminopropyl ) -19 , 11-dihydro-5H-benzo [ 2 , 3 ] pyrido [ 6 , 7-b ] azepine .
23078509738>The induction of <n>RNKP-1</n> expression in the Con A-cultured spleen cells is accompanied by increases in both NK and lymphokine-activated killer lymphocyte activities .
33199121119>Cephradine 250 mg at night for 12 months was given as a prophylactic measure to 33 female patients of mean age 41 . 6 years , who had a history in the preceding 12 months of between three and 24 ( median = 7 ) episodes of frequency and / or dysuria .
84555982745>Sterile mutants of Saccharomyces cerevisiae were isolated from alpha * cells having the <n>a / alpha aar1-6</n> genotype ( exhibiting alpha mating ability and weak a mating ability as a result of a defect in <n>a1-alpha 2</n> repression ) .
11113823954>Four cases of synovial chondromatosis are presented .
105861158929>We report here that out of the major pro-inflammatory cytokines examined , <n>IL-1alpha</n> , <n>IL-1beta</n> , <n>TNF-alpha</n> and <n>IL-6</n> , only <n>IL-6</n> was generated and secreted in PKCeta -expressing cells without any additional inducer in serum-supplemented cultures ( 10% FCS ) .
9150901549>Twenty-nine days after injection of 5 . 8 mCi of Tc-99m , which gives 28 rads to the testis , the number of sperm hads decreased to 70% of control .
69626348368>Fluorometric methods can also provide information about porphyrin binding sites that is useful in understanding porphyrin transport and clearance .
21957152816>Homozygous individuals usually develop purpura fulminans as newborns ; heterozygous protein C-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism .
10358075675><n>DAF16</n> is known to be a component of a signaling pathway that has been partially dissected genetically and includes homologues of the <n>insulin / IGF-1 receptor</n> , <n>PtdIns 3-kinase</n> and <n>PKB</n> .
68805636672>The prevalence of CPAF was similar in type 1 and type 2 diabetes , was greater in women than in men , and was significantly greater after repeated administrations than after one single administration of chlorpropamide .
74725821490>The identification of viable myocardium with both 99mTc-tetrofosmin and 201Tl can be greatly enhanced to a similar degree if the severity of reduction in activity within nonreversible defects is considered .
85980518552>Molecular analysis of a novel schizosaccharomyces pombe gene containing two <n>RNP consensus-sequence RNA-binding domains</n> .
108158072685>Interestingly , a decreased transcription from the endogenous <n>c-Myb promoter</n> was observed in several HTLV-I transformed T-cell lines .
20775602684>The role of pharmacological profiling in safety assessment .
109729908097>The <n>tumor-suppressor protein p53</n> is involved in maintaining genomic stability .
110377598067>Catch-up growth and craniofacial dimensions following administration of the antineoplastic agent vincristine to young rats .
104545504258>Previous experimental evidence had indicated that <n>Reg1</n> might target <n>Glc7</n> to nuclear substrates such as the <n>Snf1 kinase complex</n> .
103706751383>The main causes of liver disease in the patients with HCC were hepatitis C virus ( HCV ) ( 77% ) , alcohol abuse ( 73% ) , and the combination of HCV and alcohol abuse ( 50% ) .
70762226848>Recommendations to deal with these and related issues are presented .
76509583850>The changes after treatment were observed chiefly by electromyography while sensory and motor improvement were also recorded as auxiliary indicators .
108987954823>Specific <n>class I and II histone deacetylases</n> ( <n>HDACs</n> ) interact in vivo with <n>BCoR</n> , suggesting that <n>BCoR</n> may functionally link these two classes of <n>HDACs</n> .
55256525578>Preliminary report .
75926766616>Using varying conditions , three distinct complexes were shown to interact specifically with the <n>NIP region</n> , although only one correlates with repressor activity .
14199454816>Localization of the brachial plexus with the nerve stimulator is equally effective at the interscalene , supraclavicular , and axillary sites .
108252949662>Although the <n>OC promoter</n> is activated in a C terminus dependent manner , the <n>MDR</n> , LTR and <n>BSP promoters</n> are repressed by three distinct mechanisms , either independent of or involving the <n>AML C terminus</n> , or requiring only the conserved <n>C-terminal pentapeptide VWRPY</n> .
106551642656>We critically assess current systematic uncertainties and determine the primordial Li abundance within new , much tighter limits : &parl0 ; Li&solm0 ; H&parr0 ; p = 1 . 23+0 . 68-0 . 32x10-10 .
3120334486>In 64% a small cardiac vein does not exist , but its origin , the right marginal vein , joins the system of anterior cardiac veins .
22336807343>These results indicate that the cis-regulatory elements required for developmental control of the <n>HaG3-A helianthinin gene</n> are located in a 2 . 4 kb upstream region of this gene .
108018091897>Transcriptional regulation of the <n>yeast PHO8 promoter</n> in comparison to the coregulated <n>PHO5 promoter</n> .
24039263323>The <n>trk-2h oncogene</n> , isolated from the human breast carcinoma cell line MDA-MB 231 by genomic DNA-transfection into NIH3T3 cells , consists of the <n>trk proto-oncogene receptor kinase domain</n> fused to a N-terminal 41 amino acid activating sequence ( Kozma , S . C . , Redmond , S . M . S . , Xiao-Chang , F . , Saurer , S . M . , Groner , B . and Hynes , N . E .
93249883841>Substrates include the <n>p21 ( ras ) proteins</n> , <n>nuclear lamins</n> , and a series of retinal proteins .
19044379958>Transcription of the <n>metH gene in Salmonella typhimurium and Escherichia coli</n> is positively regulated by the <n>metR gene product</n> , a DNA binding protein .
67986092137>Morphine-dependent and control rats in an oral free-choice protocol were treated with gamma-vinyl GABA ( GVG ) , 60 , 120 and 240 mg / kg IP , for 3 days over three successive periods .
107068873671>Approximately 20% of ALCLs that express <n>ALK</n> do not contain the t ( 2 ; 5 ) , suggesting that other genetic abnormalities can result in aberrant <n>ALK</n> expression .
110383667329>Furthermore , loss of methylation also greatly reduced the association of another <n>yeast B-type subunit</n> , <n>Rts1p</n> .
97139967018>Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene , <n>MDR1 / P-glycoprotein</n> , in drug-selected cell lines and patients with drug refractory ALL .
91573379110>The husband in one of the married couples was treated for hepatitis of unidentified etiology in an Infectology Department four years ago .
79195402412>These genetic alterations do not affect synthesis of the major <n>c-myc protein</n> , <n>p64</n> , which is initiated from the first AUG codon in exon 2 .
20780802686>Its application in Madagascar : advantages and disadvantages .
115723885226>This paper describes the results of an initial study on the application of linear solvation energy relationships ( LSERs ) to the prediction of internal standard compounds in reversed-phase liquid chromatographic ( RPLC ) method development .
90226328987>What's new in gynecologic and obstetrical surgery .
8665777190>Treatment with heparin , <n>plasminogen</n> activators and fibrinogenolytic agents was disappointing although renal function has stabilized in one patient on long term oral anticoagulant therapy .
107995762862>M .
110721554765>There was a weak significant correlation between <n>TGF beta 1</n> levels and normal cell radiosensitivity ( lymphocyte SF2 ) .
100698159532>We now provide evidence for physical and functional interaction between <n>Doa4</n> and the proteasome .
103204806314>We describe a genetic system for further characterizing the role of the extreme C-terminus of the beta subunit of <n>E . coli RNA polymerase</n> .
13509326055>The single site of glycosylation is located near the C-terminus in the <n>N-glycosylation sequon -Asn-Cys-Ser-</n> in which Cys forms part of a disulphide bridge .
17630658706>P .
111622781005>Mental rotation of paired figures engendered activation in the left superior parietal lobule and the right frontal medial gyrus .
75391196754>When combined with independent activating mutations in the <n>c-abl kinase domain</n> or NH2-terminus , the <n>G128R</n> mutation blocked transformation by the double mutant , suggesting that the <n>G128R mutant</n> was unable to transform cells for trivial reasons .
17440421110>The <n>csbA fusion</n> was maximally expressed during early stationary phase in cells grown in Luria broth containing 5% glucose and 0 . 2% glutamine .
112853291120>9 . 7 ( 95% CI : 9 . 6-9 . 7 ) micromol / L among women ( P = 0 . 003 ) .
89223914898>A single protease-resistant structure formed by the entirety of both <n>PDZ repeats 1 and 2</n> ( <n>PDZ1-2</n> ) contains the <n>protein 4 . 1-binding site</n> .
66060435265>All other changes at the 3- , 5- , and 6-positions , as well as the replacement of the phenyl group at position 2 , caused a marked decrease of activity .
82827498642>Thomas' Hospital solution ( with 95% O2 : 5% CO2 ) can meet the metabolic demand of the ischaemic myocardium and thus increase the safe duration of cardiac arrest .
93115689248>The cleavage dipeptides of <n>C1YVV NIa protease</n> are <n>Q ( E ) / S ( A , G )</n> .
91928425830>Using mouse-human somatic hybrids and FISH analysis , the <n>PE-2 gene</n> is localized to human chromosome 19q13 . 2 , a region involved in translocations and deletions in leukemias and several solid tumors , suggesting that this novel <n>ETS factor</n> may play a role in carcinogenesis .
85050758466>Maximum number of strains ( 39 . 1% ) were resistant in S . bareilly serotype , followed by S . typhimurium ( 21 . 7% ) and least in S . typhi ( 17 . 4% ) .
69466936716>Use of prostaglandin F2 alpha ( PGF2 alpha ) in cattle breeding .
79354912625>Interestingly , these response elements display dramatically reduced affinity for <n>retinoic acid receptor-retinoid-X receptor heterodimers</n> .
97105914941>Mutations within the C terminus of <n>c-fos</n> at serine residues that are phosphorylation targets for <n>growth factors</n> and <n>MAP kinase</n> completely abrogate transactivation and block potentiation by <n>MAP kinase</n> .
29066733048>Efficacy and field evaluation of Bacillus thuringiensis ( H-14 ) and B . sphaericus against floodwater mosquitoes in California .
118857373483>The range of 200 000-300 000 spermatozoa / microl appeared to be a reasonable compromise for both criteria .
77484936754>The characterized <n>Aplysia Afurin2</n> is a candidate <n>PC</n> that may play an important role in the processing of <n>egg-laying hormone</n> ( <n>ELH</n> ) -related precursors in the secretory cells of the atrial gland .
96513671265>A role for <n>RalGDS</n> and a novel <n>Ras</n> effector in the Ras-mediated inhibition of skeletal myogenesis .
75796833079>Analyses of <n>hGMR beta subunit mutants</n> revealed two cytoplasmic regions involved in activation of the <n>c-myc promoter</n> , one is essential and the other is dispensable but enhances the activity .
93145544455>Previously , we reported that scanthrough translation , where the initiating AUG of a primary open reading frame is bypassed , is most likely to account for the presentation of cryptic epitopes from alternative reading frames within the <n>influenza A PR / 8 / 34 nucleoprotein gene</n> .
25020963151>Lowering of the renal blood flow alters the glomerular and tubular excretion processes .
98241587409>We find that <n>BCL-6 POZ</n>1 <n>domain</n>1 mutations that disrupt the interaction with <n>N-CoR</n> and <n>SMRT</n> no longer repress transcription .
113728829228>Maternal p , p'DDE and beta-HCH levels were also associated with newborn levels , but levels of PCBs were not .
112882088817>Children who developed lower respiratory tract infections or PCP had increased rates of decline of <n>CD4</n> cell counts during the first 6 months of life .
384088776>Selective stimulation of central <n>alpha-autoreceptors</n> following treatment with alpha-methyldopa and FLA 136 .
90240978989>OBJECTIVE : Our goal was to determine whether chlamydia-infected women have a higher rate of febrile complications after postpartum tubal ligation .
96327859845>The pre-mRNA splicing factor <n>U2AF</n> ( <n>U2 small nuclear ribonucleoprotein particle [ snRNP ] auxiliary factor</n> ) plays a critical role in 3' splice site selection .
31434859815>The <n>Euglena ribosomal protein gene cluster</n> resembles the <n>S-10 ribosomal protein operon of Escherichia coli</n> in gene organization and follows the exact linear order of the analogous genes in the tobacco and liverwort chloroplast genomes .
109053523303>The linear plasmid pCLU1 from the yeast Kluyveromyces lactis normally replicates in the cytoplasm , with the aid of the helper linear plasmid pGKL2 , using <n>terminal protein</n> ( <n>TP</n> ) as a primer .
117915711654>A high-efficiency cross-flow micronebulizer interface for capillary electrophoresis and inductively coupled plasma mass spectrometry .
94679558699>This hypothesis is consistent with the occurrence of <n>PEA3 binding sites</n> in the <n>PEA3 promoter</n> and with the ability of <n>PEA3</n> to transactivate this promoter .
63406436131>DMCM also permits extension of the possibilities of obtaining and transplanting donor organs .
106494494262>The sequences showed extensive homologies with <n>squalene synthase genes</n> and enzymes from a number of other organisms and extreme amino acid conservation within the binding and catalytic domains .
110945909909>When 10 fields were analysed , a strong relationship was found between the presence of bacteria on Gram staining and the final diagnosis of VAP ( for PSB and PTC respectively : sensitivity 74 and 81% , specificity 94 and 100% , positive predictive value 91 and 100% , negative predictive value 82 and 88% ) .
113711606884>They correspond to nucleotides equivalent to base-pair C1-G72 and discriminator base A73 in the amino acid-acceptor branch of the molecule .
114006441804>As a reflection of uncertainties in the estimates for individual sources , the 90th percentiles of PCDD / F releases for 1999 ranged up to 4 . 1 g I-TEQ / y .
84395978404>The evaluation was performed using a retrospective study design with newborn blood samples from three screening centres .
106695947649>Two distinct <n>Salmonella fimbrins</n> , <n>AgfA</n> and <n>SefA</n> , comprising thin aggregative fimbriae <n>SEF17</n> and <n>SEF14</n> , respectively , were each genetically engineered to carry <n>PT3</n> , an alpha-helical 16-amino acid Leishmania T-cell epitope derived from the <n>metalloprotease gp63</n>1 .
10857215890>The MRS II meets a high methodological standard as an instrument standardized in the population .
40515214729>Duration of remission in advanced gastric cancer patients responding to sequential dose of MTX and 5-FU .
94685149346>Northern analysis indicated differential expression by tissue with highest expression in the heart .
105402929275>These data show that the <n>spv virulence genes</n> belong simultaneously to several regulons in the cell , raising the possibility that <n>spv</n> expression can be fine-tuned in response to multiple environmental inputs .
86493725423><n>Clb2 / Cdc28 kinase</n> is not required for the repression of <n>MCB-binding factor</n> transcriptional activity in G2 and M phase .
79570855319><n>Cbf3</n> contains three proteins , <n>Cbf3a</n> , <n>Cbf3b</n> and <n>Cbf3c</n> .
16583569067>The results of induced coexpression were also supported by rapid generation of FeLV recombinants when FeLV-C was used to infect the feline 3201B cell line that constitutively expresses high levels of endogenous FeLV-specific mRNAs .
25929613245>COGLAB includes measures of preattentional , attentional , conceptual , and psychomotor performance .
10479382317>We discuss these results in terms of the influence that time and nutritional constraints have on odonate development patterns and fitness .
27937536269>Within each lobe , the PA dispersion was up to 10 cmH2O at CFV of 90 l / min ; when flow decreased , PA at all sites decreased , as did the intralobar dispersion .
105642317786>N . van Hoek , and M .
2856622193>Use of serum <n>thyroglobulin</n> determination in the follow-up of differentiated carcinomas of the thyroid .
70646626827>Large and small medullary lesions inhibited the occurrence of target fibres in the tenotomized muscles , the smallest one being neurolysis of the dorsal roots .
16757632275>No such benefits were seen for children with <n>CD4+</n> counts below 0 . 2 x 10 ( 9 ) per liter at entry .
98441062645><n>Pyk2</n> phosphorylation increased upon adherence of FLG 29 . 1 cells to <n>fibronectin</n> and to ST2 stromal cells .
63143126104>Supplementing a soybean protein and sucrose-based diet with levels of 2 . 2 , 11 , and 55 ppm of the antibiotic , from the two sources each with two different purities , improved weight gain of chicks an average of 23% and improved feed efficiency an average of 13% at the higher levels ( all P less than . 01 ) .
7828584357>Mutagenesis of <n>IM1</n> enhances the ability of <n>c-Fos</n> to activate an <n>AP1 bearing promoter</n> .
10625721448>Hypothermia After Cardiac Arrest ( HACA ) Study Group .
76538122570>Intrathecal <n>acetyl cholinesterase</n> inhibitors produce analgesia that is synergistic with morphine and clonidine in rats .
95905405361>The <n>bZP2 cDNA ( 115-1914 nt , 1 . 8 kb )</n> , excluding sequences coding for N-terminal signal sequence and C-terminal transmembranelike domain , was PCR amplified and <n>Sac1-Sal1 restricted fragment</n> cloned in frame downstream of the T5 promoter under the <n>lac operator</n> control in a pQE-30 vector .
23301102981>Combining multiple laboratory studies may be of value in predetermining the eventual outcome in near-drowning .
87271928710>STUDY DESIGN .
75009505429>A tobacco homologue ( <n>trolC</n> ) of the <n>rolC gene of the Agrobacterium rhizogenes Ri-plasmid</n> was cloned and sequenced from Nicotiana tabacum L . cv .
92082149161>Sternocleidomastoid , neck or facial muscles wasting were also found in three cases .
113694101211>The first hypothesis was supported in the sense that stimulus differences might affect behaviour even without their successful attentive processing in normal participants .
93891379340>The prescription for apoplexy includes C1-7 , T1-9 and L2-4 .
75593475936>The expression of the putative operon <n>bglPH</n> of Bacillus subtilis was studied by using <n>bglP'-lacZ transcriptional fusions</n> .
3345706585>The correlation between PaCO2 and PtcO2 in RDS was insufficient to make clinical judgement .
76530944507>A series of amino terminal deletion mutants ( d10 , d20 , d27 , d31 , d40 , d44 , and d73 ) were compared for processing , cell surface expression , and maintenance of their biological attributes by recombinant expression of mutant genes using a plasmid vector ( pcDL-SR alpha-296 ) in CV-1 and HeLa cells .
107998797042>Cloning and characterization of <n>human Lnk</n> , an adaptor protein with <n>pleckstrin</n> homology and <n>Src homology 2 domains</n> that can inhibit T cell activation .
73938567238>As a result , beta-apo-8'-carotenoic acid ethyl ester ( apo-EE ) was used as a reference standard in Experiments 4 to 6 .
105567511538>Nevertheless , in view of the potential transmission rates of HGV and the lack of effective immunization , HGV should be regarded as a potential occupational hazard for medical and dental staff .
79252827946>Disruption of any one of the four genes encoding the newly identified <n>SRP proteins</n> results in slow cell growth and inefficient protein translocation across the ER membrane .
117780441623>We derive joint probability density distributions for three key uncertain properties of the climate system , using an optimal fingerprinting approach to compare simulations of an intermediate complexity climate model with three distinct diagnostics of recent climate observations .
106657981024>An increase in the level of serum enzymes , such as <n>aspartate transaminase</n> , <n>alkaline phosphatase</n> , <n>creatine phosphokinase</n> , <n>lactate dehydrogenase</n> after D . russelli venom injection in albino rats is indicative of cell or tissue damage .
32648868839>Among a population of 18 , 175 children below 7 years of age in medium sized towns and rural areas in south-western Germany 552 ( 3 . 03% ) cases of croup were registered during a 12 months period in 1984-85 by their physicians .
81924517001>The 7-day treatment resulted in a decrease in mitochondrial uptake of Rh123 and an increase in NAO uptake .
15777407588>Primer extension and <n>mung bean and S1 nuclease</n> mapping indicated multiple transcription initiation sites and were consistent with Northern analyses .
30623709130><n>GCN4</n> encodes a transcriptional activator of amino acid biosynthetic genes in Saccharomyces cerevisiae .
93873339336>The progress of morphological research on the parabrachial nucleus .
81444976726>The cysteine-rich region of <n>raf-1 kinase</n> contains zinc , translocates to liposomes , and is adjacent to a segment that binds <n>GTP-ras</n> .
97270463694>The <n>CBF1 site</n> within <n>HS2</n> resides near sites for hematopoietic regulators such as <n>GATA-1</n> , <n>NF-E2</n> , and <n>TAL1</n> .
113509826703>Here we provide the first evidence for the involvement of <n>GCN1-GCN2</n> interaction in activation of <n>GCN2</n> per se .
31254222150>The results of these experiments indicate that at least two upstream activator sequences ( UAS ) mediate maximum induction by galactose .
85765469466>In a second series of experiments , the efficacy of PDC / HDC Ac was evaluated in both single and multiple dose regiments .
85845305551>Significant correlations existed between FEV1 and the corresponding values of Raw , MEF50 and MEF25 , although there were considerable individual differences between test results .
66698646420>The liver in the severely ill .
93598446592>20% of total <n>HSL transcripts</n> in human subcutaneous adipocytes .
98226853289>Western analyses with antisera raised against <n>Lu-ECAM-1 peptides</n> show that the N-terminal region of the predicted open reading frame is present only in the larger size proteins ( i . e .
77558847726>Intrastriatal grafts of nigral and adrenal tissues have been found to be effective in alleviating many of the simple motor and sensorimotor deficits associated with lesions of the nigrostriatal dopamine system .
109099735449>In contrast , the action of <n>GLP-1</n> at the <n>CRE</n> was not blocked by cotransfection with <n>M1-CREB</n> , an isoform that lacks a consensus serine residue serving as substrate for PKA-mediated phosphorylation .
11016737852>Post-operative functional outcome is related to pre-operative functional status .
9642276296>The cleavage of <n>Fak</n> by <n>caspases</n> may thus play an important role in the execution of the suicide program by disabling the anti-apoptotic function of <n>Fak</n> .
4299494045>As authorized by the World Health Organization 29th Expert Committee on Biological Standardization , the preparation of <n>human prolactin</n> in ampoules coded 75 / 504 has been established as the International Reference Preparation ( IRP ) of <n>human prolactin</n> for immunoassay .
6825641955>Many of these landfill operations were undertaken in the early 1950s and 1960s , when knowledge regarding the safe and prolonged containment of the waste buried was nonexistent or minimal at best .
17109791802>The <n>SH2</n> and <n>SH3 domains</n> of <n>pp60src</n> direct stable association with tyrosine phosphorylated proteins <n>p130</n> and <n>p110</n> .
118746371768>The use of highly active antiretroviral therapy ( HAART ) has resulted in significant improvements in the treatment of HIV infection , including a decrease in the incidence and severity of several acquired immune deficiency syndrome ( AIDS ) -related malignancies .
75233637693>A particularly striking <n>HpaII</n> tiny fragment island , extending over nearly 2 , 000 base pairs , surrounds the <n>USF2 translation initiation site</n> .
105085225553>Our results implicate <n>TGF-beta RII</n> as a direct target of <n>EWS-FLI1</n> .
27764713475>It was possible to classify the animals into high and low responders according to the pattern of humoral immune response .
112643721072>Requirements for the nuclear-cytoplasmic translocation of <n>infected-cell protein 0</n> of herpes simplex virus 1 .
95709449612>Localization of 67 exons on a YAC contig spanning 1 . 5 Mb around the <n>multidrug resistance gene region</n> of human chromosome 7q21 . 1 .
10448440297>The role of 'scientific psychiatry' in understanding patients with chronic schizophrenia or severe personality disorder .
96435484945>The genes encoding <n>( 2Fe-2S ) plant-like ferredoxins</n> were studied in the widely used cyanobacterium Synechocystis PCC6803 .
7899634303>PURPOSE : The aim of this study was to evaluate the bony anchorage of a new implant ( orderly wired surface effect with alloy Ti Al Va and ordered pores of 488 mu ) .
16609257395><n>Transfer RNA genes from Dictyostelium discoideum</n> are frequently associated with repetitive elements and contain consensus boxes in their 5' and 3'-flanking regions .
66895136447>Ultrastructural studies of retinopathy of premature infants .
25925433243>The present studies compare the biochemical characteristics , Kanagawa hemolysin reactions , and plasmid profiles of 13 patient and 221 environmental isolates of the organism .
71843751510>A preliminary study of vincristine , methotrexate , and prednisolone ( VM*P ) combination chemotherapy for advanced adult non-Hodgkin's lymphoma .
4016764683>Accurate pathologic staging identifies patients who are potentially curable with radiotherapy .
13778182576>In addition , <n>C / EBP beta</n> and <n>C / EBP gamma</n> readily heterodimerize with each other as well as with <n>C / EBP alpha</n> .
80236621687>Intraoperative measurement of activated partial <n>thromboplastin</n> time and <n>prothrombin</n> time with a new compact monitor .
99173893334>The pattern of <n>RNase E</n> digestion of <n>finP305 RNA</n> differed from <n>FinP</n> , and <n>GST-FinO</n> did not protect <n>finP305 RNA</n> from cleavage in vitro .
19709262588>During exercise K+ is released from contracting muscle and plasma K+ concentration rises .
92359985114>Second , the membrane expression of alpha and beta subunits was mimicked by cholesterol and 17-ketocholesterol , both of which inhibit <n>HMG-CoA reductase</n> .
95315596557>In vitro affinity analyses demonstrated that recombinant 130-kD protein directly interacts with <n>ZO-1</n> and the cytoplasmic domain of <n>occludin</n> , but not with <n>ZO-2</n> .
10488875142>Clinical differentiation of patients with mild diplegic cerebral palsy ( CP ) and idiopathic toe walking ( ITW ) can be difficult .
87027285206>Next , we stably overexpressed <n>wild-type Shc</n> or <n>Y317F mutant Shc</n> into HIRc cells .
7735833206>CONCLUSIONS : A comparison of the <n>LysU</n> crystal structure with the structures of <n>seryl- and aspartyl-tRNA synthetases</n> enables a conserved core to be identified .
29635173670>Quantitative analysis of the coronary stenosis was assessed before and after PTCA , and the dilatation resulted in an increase in minimal luminal cross-sectional area from 1 . 1 + / - 0 . 8 to 2 . 7 + / - 1 . 2 mm2 .
92169019174>Thirty-two rats were divided into four groups .
112388845872>Mice homozygous for the <n>dlg</n> mutation exhibit growth retardation in utero , have hypoplasia of the premaxilla and mandible , have a cleft secondary palate , and die perinatally .
75763076430>Here we focused on the role of the 5' proximal regulatory cassette ( -190 ; +53 bp ) of the <n>rat enkephalin</n> ( <n>rENK</n> ) gene in the developmental regulation of the <n>enkephalin</n> phenotype .
84193765774>The nucleotide sequence of the gene predicts a polypeptide of 215 amino acids ( 25 . 2 kDa ) with two putative membrane-spanning domains .
99992569997>Quantum-statistical theory of high-field transport phenomena .
83099758293>Depletion of dopamine in the nucleus accumbens led to a dramatic shift in behavior in which there was a significant decrease in lever pressing but a significant increase in consumption of lab chow .
16626099964>The two genes code for <n>polypeptides of 420 amino acids ( M . HgiCI )</n> and <n>345 amino acids ( R . HgiCI )</n> .
11585125931><n>Glucose-6-phosphate dehydrogenase</n> ( <n>G-6-PD</n> ) deficiency in the newborn .
50259183004>Angiography of aneurysmal bone cyst .
92338093788>The two mouse lines carrying the unfragmented <n>Hnf3g-lacZ YAC</n> showed tissue-specific , copy number-dependent and position-independent expression , proving that 170 kb of the <n>Hnf3g</n> locus contain all elements important in the regulation of <n>Hnf3g</n> .
81576635128>These results are the first to demonstrate the structural organization of a vertebrate gene encoding an integral membrane protein of the nuclear envelope that may be a member of a family of polypeptides conserved in evolution .
102339469923>Previous work has shown that spleen necrosis virus ( SNV ) long terminal repeats ( LTRs ) are associated with Rex / Rex-responsive element-independent expression of bovine leukemia virus RNA and supports the hypothesis that SNV RNA contains a cis-acting element that interacts with <n>cellular Rex-like proteins</n> .
7192722895>After successful subtotal parathyroidectomy , evident by the decrease of serum <n>iPTH</n> levels , both the CL of group 2 PMNs and the ability of group 2 sera to induce augmented CL in normal PMNs decreased ( p < 0 . 025 ) .
72785787135>Current status of chemotherapy for Hodgkin's disease .
87501738737>AIMS / METHODS : Reticuloendothelial system function , as assessed by clearance of radiolabelled bacteria , was evaluated in acute liver injury induced by D-galactosamine in rats , and compared with that after 70% liver resection model .
4396183539>Lethal Tachmalcor ( 4- ( 3'-diethylamino-2'-hydroxypropyl ) -ajmaline ) poisoning in childhood .
1098592818><n>IgG</n> levels of 1 / 100 were present in only four out of ten samples obtained 150 days after the clinical onset .
76793906226><n>RNase</n> protection and primer extension assays confirmed that the 5' non-coding exon is included in the DDT1 <n>aFGF mRNA</n> and that a major transcription start site is approximately 136 bp upstream of the 5' non-coding splice junction of this exon .
94720386072>Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism .
5786485722>Functional effects following subacute administration .
16987729324>( 1988 ) J .
28302148407>The effect of acetazolamide ( ACZ ) on HCO3- and Cl- activities in inner ear fluid was investigated by ion-selective microelectrode methods .
89954106089><n>Eukaryotic initiation factor 3</n> ( <n>eIF3</n> ) is a large multisubunit complex that stabilizes the ternary complex , <n>eIF2</n> x <n>GTP</n> x <n>tRNA ( Met ) i</n> and promotes mRNA binding to the <n>40 S ribosomal subunit</n> . <n>eIF3</n> also functions as a ribosome subunit anti-association factor .
29582041309>To investigate the effects of isotretinoin on <n>HDL</n> , we measured <n>HDL-C</n> , <n>HDL</n> phospholipids ( <n>HDL-PL</n> ) , <n>apoprotein A1</n> ( <n>apo A-1</n> ) , and <n>HDL-C</n> subfractions ( <n>HDL2-C</n> and <n>HDL3-C</n> ) in 24 healthy , male patients receiving a 16-week course of isotretinoin ( 1 . 0 mg / kg / day ) for treatment of severe acne vulgaris .
75651042019>The expression of the <n>pilin gene</n> , <n>tcpA</n> , is dependent upon <n>ToxR</n> and upon <n>ToxT</n> .
25421943184>These results indicate that patients who undergo postoperative irradiation for low grade spinal astrocytomas and localized spinal ependymomas achieve excellent survival .
6026222592>A one-week ulcer therapy with atropine and Vikalin ( Roter ) led to a significant ( p less than 0 . 01 ) reduction of the nocturnal proteolytic activity .
88582117644>This <n>GAP</n> activity was observed in 3T3-L1 adipocyte lysates , and was able to accelerate the hydrolysis of the [ alpha-32P ] GTP bound to <n>GST-Rab4</n> into [ alpha-32P ] GDP .
92259982678><n>NF-kappa B / Rel transcription factors</n> participate in the activation of numerous genes involved in immune regulation / inflammation including cytokines , cell surface receptors , adhesion molecules , and acute phase proteins .
105559649552>S . , Kim , S .
87404163883>The predicted protein , <n>Seb1p</n> , consists of 82 amino acids and contains one potential membrane-spanning region at the C-terminus but no N-terminal signal sequence .
22336262878>Droperidol-induced extrapyramidal symptoms in an adolescent following strabismus surgery .
7651734493>Northern blot analysis revealed the expression of <n>LIMK-1 mRNA</n> predominantly in the brain and the expression of <n>LIMK-2 mRNA</n> in various tissues in the rat .
86470861597><n>Cyclin-dependent kinase-2</n> ( <n>Cdk2</n> ) forms an inactive complex with <n>cyclin D1</n> since <n>Cdk2</n> associated with <n>cyclin D1</n> is not phosphorylated by <n>Cdk7-cyclin-H</n> .
110732185767>The sixth nucleotide was bulged out to allow stacking of this U . G pair on the adjacent helical region .
20221881566>I propose that their gene products bind to the chromatin to establish or maintain a proper higher order structure as a prerequisite for a regulated gene expression .
65992826355>The invasive pattern of squamous cell carcinoma in the mandibular gingiva .
11123054960>Paraneoplastic rheumatic syndromes .
100229789524>The distribution of the various repeats suggests its organization is similar to the beta-heterochromatic regions near the base of the major chromosome arms .
8304342499>In the present report , 66 hemochromatosis families yielding 151 hemochromatosis chromosomes and 182 normal chromosomes were RFLP-typed with a battery of probes , including two newly derived polymorphic markers from the 6 . 7 and <n>HLA-F loci</n> located 150 and 250 kb telomeric to <n>HLA-A</n> , respectively .
26743279941>The <n>p34 . 8 gene</n> has a strong codon usage bias which is strikingly different from that of the <n>polyhedrin gene</n> .
113694537720>There was an increase in protein binding onto this element only after peptide treatment .
32580693956>The purposes of this study were 1 ) to examine the effect of high intensity , low frequency transcutaneous electrical nerve stimulation at auricular acupuncture points on experimental pain threshold measured at the wrist and 2 ) to determine the changes in effect over time .
75651134287>The <n>chloramphenicol-resistance transposon Tn4451</n>1 undergoes precise conjugative deletion from its parent plasmid plP401 in Clostridium perfringens and precise spontaneous excision from multicopy plasmids in Escherichia coli .
13980719865>These temperature- and cold-sensitive strains were used to prepare extracts deficient in <n>BRF1</n> activity and were tested for transcriptional activity by <n>RNA polymerases I , II , and III</n> in vitro .
91191128182>These data are consistent with a model in which <n>GATA-5</n> performs a unique temporally and spatially restricted function in the embryonic heart and lung .
86518538611>Mesial temporal sclerosis .
110700565075>The <n>Cili-2 sequences</n> possess similarity to the <n>RNaseH domain</n> of <n>Lian-Aa1</n> , a mosquito non-LTR retrotransposon .
77370247684>Whole bowel irrigation is a recently described technique to enhance the passage of drugs already beyond the pylorus .
22612542901>Experiments showed that temporary arrest of pulmonary circulation under conditions of extracorporeal circulation is attended by the development of ischemia of the respiratory pulmonary tissue .
27609225439><n>Heterogeneous nuclear ribonucleoprotein ( hnRNP ) core protein A1</n> is a major component of <n>mammalian hnRNP 40 S particles</n> .
67143546481>Monkeys were evaluated before and after unilateral and serial bilateral removal of superior temporal cortex .
96302458544><n>Yeast U1 snRNP</n> is considerably more complex than its metazoan counterpart , which suggests possible differences between yeast and metazoa in early splicing events .
98774171769>Plasma <n>CCK</n> levels were determined at regular intervals .
113810945354>In addition , <n>stonin 2</n> binds to the <n>C2B domains</n> of <n>synaptotagmins I and</n> II .
10376446249>12 healthy women ( age 18-38 years ) were examined using the 2-hour's method of passive leg rising ( PLR ) in follicular ( FP ) and luteal ( LP ) phases of normal ovulatory cycle .
9512550230><n>E1A</n> represses <n>apolipoprotein AI enhancer</n> activity in liver cells through a pRb- and CBP-independent pathway .
104412439669>RESULTS : Circulating <n>leptin</n> concentrations in AN were 3 . 5+ / -0 . 5 versus 7 . 6+ / -1 . 2 ng / ml in control subjects .
77489523087>In addition , two internal promoters , <n>PmiaA</n> and <n>P1hfq</n> were identified and mapped to 201 and 837 nucleotides upstream from the respective translation start sites .
15183962140>George T .
44882324991>Effects of alcoholism on the family .
17913632404>These results were superior to those in 24 patients with conventional end-to-end sutures on clinical testing .
107491661720>These results indicate that virulence-associated genes and their overall chromosomal arrangement are relatively well conserved between B . henselae and other gram-negative bacteria such as A . tumefaciens .
46383655065>Effect of triftazin and aminazin on hippocampal bioelectric activity .
13895732021>TBPf is defined as a quotient of the difference of the first and the second measurement : TBPf = ( P1 - P2 ) / ( A1 - A2 ) .
117415549931>Comparison of remnant-like lipoprotein particles in postmenopausal women with and without coronary artery disease and in men with coronary artery disease .
14786728809>One phage clone contains a junction between alpha satellite DNA and a novel low-copy repeated sequence .
97054973907>The <n>yeast MMS2 gene</n> was cloned by its ability to complement the methyl methanesulfonate sensitivity of the <n>mms2-1 mutant</n> and was later shown to be involved in DNA post-replication repair .
39257124572>Biopsies of the jejunal mucosa have shown abnormal enzyme activity or deficiencies in transport mechanisms .
21264177694>In the controls , it was found that all right-handed and 10 out of 14 left-handed control subjects showed a right VHF ( i . e . , left hemisphere ) advantage .
9267439382>Genes belonging to the <n>ras superfamily</n> encode <n>low-molecular-weight GTP / GDP-binding proteins</n> that are highly conserved in wide variety of organisms .
82401708225>Four forms of salmonellosis were recognised in feedlots and during transport by sea : septicaemic , and acute , subacute and chronic enteric .
93684194712>A cDNA encoding a <n>MYC-related DNA binding protein</n> was isolated by DNA-ligand binding screening , using the 67-bp region as a probe , and designated <n>rd22BP1</n> .
81634983569>Two phosphopeptides , identified as <n>RS- [ 32P ] SGASGLLTSEHHSR</n> and <n>S- [ 32P ] SGASGLLTSEHHSR</n> , were obtained after stoichiometric phosphorylation and trypsinization of the peptide .
114435094504>DESIGN : Prospective cohort study with a 20 y follow-up period , the First National Health and Examination Survey ( NHANES 1 ) Epidemiologic Follow-up Study ( NHEFS ) .
94631749414>We present the preliminary results obtained on 36 patients which were followed for a mean period of 12 months .
90233781202>Moreover , expression of <n>CBF1</n> in yeast was found to activate transcription of reporter genes containing the <n>C-repeat / DRE</n> as an upstream activator sequence but not mutant versions of the DNA element .
22036722822>The computer-programmed cytocentrifuge is currently most popular .
75927309079>Levels of <n>TSG-14 protein</n> ( also termed <n>PTX-3</n> ) become elevated in the serum of mice and humans after injection with bacterial lipopolysaccharide , but in contrast to conventional acute phase proteins , the bulk of <n>TSG-14</n> synthesis in the intact organism occurs outside the liver .
86847428666>OBJECTIVE : To compare pregnancy complications in women having genetic amniocentesis at 11-14 weeks versus those undergoing amniocentesis at 16-19 weeks' gestation .
88914748844>These findings suggest that the F-wave may be elicited in motoneuron of different depolarization threshold but primarily in larger and faster nerve fibers , with a lower threshold of depolarization .
10446833293>Microcirculatory oxygenation and shunting in sepsis and shock .
87564336731>Thus , the characterization of the promoter region should help to define regulatory elements that control neuron-specific and developmental expression of the <n>MAP1B gene</n> .
101006056897>The induced respiratory burst was investigated by the intracellular oxidative transformation of dihydrorhodamine 123 to the fluorescent dye rhodamine 123 via flow cytometry .
77840794855>Transfection of non-deleted expression vector into NIH3T3 cells results in acquisition of focus-forming activity while a deleted form of expression vector fails to show this activity even in the presence of <n>basic FGF</n> .
92059656211>The results suggest that the bulbospinal micturition reflex evoked by bladder filling and L-dopa involves a descending pathway where transmission is partly mediated by <n>spinal alpha 1-adrenoceptors</n> .
88336538348>Although <n>isl-1</n> binds to both the <n>insulin</n> and <n>amylin gene promoter elements</n> in vitro , these sequences display marked differences in their relative transcriptional properties when ligated adjacent to a heterologous promoter and transfected into InR1 -G9 islet cells .
115707355033>RESULTS : The subjects in the augmented feedback group significantly reduced their peak vertical ground reaction force in both post-test conditions ( 2-minute post-test reduction , 0 . 85+ / -0 . 62 ; 1-week post-test reduction , 0 . 74+ / -0 . 58 ) as compared to the sensory , control I , and control II feedback groups .
49196135239>Study of <n>antinuclear autoantibodies</n> by immunofluorescence technic in <n>collagen</n> diseases .
8435755533>PNT , ADD and BSS in the initial stage of kindling , kindling rate for the stage-3 and -5 seizures , seizure parameters at the first stage-3 and -5 were recorded and compared to the values of saline-treated , control group .
63699546167>Effects of negative pleural pressure on left ventricular hemodynamics .
14471892462>These data indicate that <n>RNK-Met-1</n> is a <n>serine protease</n> with unique activity that is expressed in the granules of large granular lymphocytes .
117753011619>No effect of the intervention on depression scores was found .
13286814046>Ruddell , M .
10709705528>Rigid point feature registration using mutual information .
112792079242>Together , these results identify <n>HPK1</n> as a new component of <n>TCR</n> signaling .
118950242768>Nine cases of GBS and five of TM reported to the active AFP surveillance were not found in the hospital searches .
104775453096>The B-oligomer of <n>pertussis toxin</n> deactivates <n>CC chemokine receptor 5</n> and blocks entry of M-tropic HIV-1 strains .
118937671798>The mass-specific resting minute ventilation ( E ) and the ventilatory equivalent ( E / ( O ( 2 ) ) ) were approximately the same at the two ages , with a breathing pattern significantly deeper and slower at day 1 .
106840971283>Forty 4-month old SD female rats were randomly divided into four groups , namely sham operation , bilateral ovariectomy , ovariectomy plus supplementary ethinyl estradiol ( 0 . 2 microgram / 100 g B .
91190314373>The different <n>holoenzyme RNA polymerases</n> generated upon reconstituting these mutants independently with <n>core RNA polymerase</n> ( <n>alpha2beta beta'</n> ) have shown reduced transcriptional activity in comparison to the enzyme containing <n>wild-type sigma factor</n> .
39286784579>Thyrotropin-releasing hormone-induced contraction of urethral and vaginal muscle .
92547092354>Contacts between Bacillus subtilis catabolite regulatory protein <n>CcpA</n> and <n>amyO</n> target site .
90858426274>Thus , the <n>tri-snRNP-specific 27K protein</n> could potentially be involved in <n>SR</n> protein-mediated protein / protein interactions and , additionally , its phosphorylation state could modulate pre-mRNA splicing .
94070367165><n>Tcn1p / Crz1p</n> , a calcineurin-dependent transcription factor that differentially regulates gene expression in Saccharomyces cerevisiae .
78406431433>A comparison of the Flavobacterium <n>glycosylasparaginase</n> with a mammalian <n>glycosylasparaginase</n> revealed 30% structural identity and 60% overall similarity between the prokaryotic and eukaryotic forms of the enzyme .
94535376963>This region , however , contains a CCAATC box in the reverse complement and several GC boxes that are recognition sites for <n>SP1</n> .
93715643955>Furthermore , the amount of <n>tRNA ( 3Lys )</n> that was placed onto viral RNA in mutated viruses was significantly less than that placed in the wild-type virus .
6790572550>All 62 isolates were resistant to lincomycin , colistin , nystatin , amphotericin B , trimethoprim lactate , polymyxin B , and anisomycin .
94114599366>However , in a new experiment in which the deletion task was presented as a puppet game , and with pretraining and selection on vowel deletion , a significantly higher level of success was achieved by the children working with the CVCC material .
68566696652>These results indicate that significant pulmonary metabolism of 5-HT followed by efflux of 5-HIAA into venous output occurs during single-pass circulation .
20732228073>Thirty seven patients ( amitriptyline n = 16 , moclobemide n = 21 ) completed the six week protocol , which was conducted under double blind conditions .
88561328806>Evidence for the promoting role of the <n>intra-uterine kinin</n> release in the development of late hypertonic saline-induced abortion .
113133987697>Cross-linking <n>FcalphaR</n> on <n>wt-ITAM</n> or <n>IIA-ITAM</n> cells triggered equivalent PI 3-kinase-dependent activation of <n>PKBalpha</n> .
106518053120>Characterization of a <n>human alternatively spliced truncated reduced folate carrier</n> increasing folate accumulation in parental leukemia cells .
34293719749>We conclude that cephalothin clearance of S . aureus from a site accessible to phagocytes was delayed when compared to a phagocyte-inaccessible site .
11313342673>Recently , we discovered that alanine substitutions of the active center cleft residues significantly impair the depurinating and ribosome inhibitory activity of <n>PAP</n> .
114746421361>The decrements in cerebrovascular resistance induced by hexamethonium , in mm Hg ml ( -1 ) . min ( -1 ) , were : under control .
78962914475>The resulting integrated physical , genetic , and cytogenetic map constitutes a resource for the characterization of genes that may be involved in the WAGR syndrome .
85217808491>Umweltchem .
27401963428>In Experiment 2 , we again used classification , but the fixed standard 75 was not at the center of the range of target numbers ( 20 , 21 , . . .
55020545576>Leukemia in twins : world-wide review of clinical cases .
22470697464>The <n>TUP1 gene</n> was isolated in a screen for genes that regulate mating type ( V . L .
75882402700>The <n>Caenorhabditis elegans death susceptibility gene</n> , <n>ced-3</n> , has a number of homologs in vertebrate species , including <n>interleukin-1 beta ( IL-1 beta ) -converting enzyme</n> ( <n>ICE</n> ) , <n>Ich-1long</n> , and <n>CPP32</n> .
37852126352><n>RPS14</n> introns 3 and 4 both contain <n>Alu sequences</n> .
98047798891>Transcription factors of the <n>Stat family</n> are controlled by <n>protein kinases</n> .
91110489019>A novel , <n>testis-specific mRNA transcript</n> encoding an <n>NH2-terminal truncated nitric-oxide synthase</n> . mRNA diversity represents a major theme of <n>neuronal nitric-oxide synthase</n> ( <n>nNOS</n> ) gene expression in somatic cells / tissues .
115358328344>The isoform , designated <n>HDAC9a</n> , is 132 aa shorter at the C terminus than <n>HDAC9</n> .
74555216859>The ESEG's are a direct result of the NEXT study .
28828933591>Body temperature and overall conductance in the cold appear to be more variable in P . s . campbelli than in nominative sp .
20172712627>After 6 months , definite improvement in strength occurred in 4 of 7 carnitine-treated patients and in none of 7 controls .
1003700434>Fifty-seven patients aged < 55 years with acute lymphoblastic leukemia ( ALL ) in second or third bone marrow ( BM ) relapse or refractory to first-line therapy were enrolled in an Italian cooperative study .
109515797777>After gamma-irradiation , the majority of F9 cells undergo apoptosis implying that <n>wt-p53</n> likely triggers pro-apoptotic gene expression in DNA damaged cells .
87173914630>While fusion to the N-terminus required a linker to become surface accessible , both fusion to the N-terminus and to the C-terminus was compatible with particle assembly and preserved the native antigenicity and immunogenicity of <n>HBcAg</n> .
10573781393>Studies have substantiated the involvement of numerous loci on certain chromosomes ; in excess of 10 chromosomes are thought to be involved .
10343189202>Grade 3 mucositis was reported in 1 patient .
112270394180>Multiparous women presented higher BMI ( P = 0 . 01 ) and PBF ( P = 0 . 03 ) compared with primi- and nulliparous groups .
86397424168>Isolation by PCR of a cDNA clone from pea petals with similarity to petunia and <n>wheat zinc finger proteins</n> .
118864731782>Gastritis score was significantly lower in nodminus sign / CagAminus signchildren than in nod+ / CagAminus sign ( p = . 004 ) , nodminus sign / CagA+ ( p = . 002 ) and nod+ / CagA+ ( p < . 001 ) , both in the antrum and corpus .
11737900496>We found no correlation between plasma COP and body weight at the same age ( r2 = 0 . 05 , P = 0 . 155 ) .
82646315448>The 227-to-239 region blocked <n>ADR1</n> activity independently of the <n>TAD</n> present on <n>ADR1</n> , <n>ADR1</n> DNA binding , and specific <n>ADH2 promoter sequences</n> .
61854936129>A polypeptide chain of 34 residues of the deduced yeast amino acid sequence closely resembles a peptide sequence at the ADP binding site of <n>bovine muscle pyruvate kinase</n> .
63604264925>The enzymic hydrolysis of urea produces ammonia which causes a vivid yellow to purple colour change in the pH indicator .
86661028945>ZIOS was significantly more sensitive than all subsequent methods , and Ptc , O2 was significantly more sensitive than FEV1 .
33810394069>In contrast , the MAN showed a unimodal , skewed distribution , with a range from approximately 1 to 14 micron and a maximum at 3-4 micron .
104529517495><n>Nuclear hormone receptors</n> ( <n>NRs</n> ) are ligand-inducible transcription factors that mediate critical functions in many species .
116870831535>OBJECTIVES : The objective of this review was to assess the effects of prophylactic prostaglandin use in the third stage of labour .
98624965013>Ethylene is involved in endosperm rupture and high-level <n>betaGLU I</n> expression ; but , it does not affect the spatial and temporal pattern of <n>betaGLU I</n> expression .
68683456664>The presence of visna-maedi in Italy is reported for the first time .
60485055879>Derivatives of fluorene .
76361799071>The normal cell cycle is regulated by several molecules , such as the <n>tumor-suppressor protein pRb</n> , the <n>G1 cyclins</n> , the <n>cyclin-dependent kinases</n> , and their inhibitors .
82918868271>Fast continuous expansion .
83080087962>In this paper , we demonstrate that binding of the <n>GA-binding protein</n> ( <n>GABP</n> ) to <n>ets sequence motifs</n> within each repeated unit is required for transcriptional activation of the <n>COXIV promoter</n> .
94420179863>( 1997 ) Science 275 , 1927-1930 ) .
67313027390>No patient with bradyarrhythmia -related SCD had manifest atrioventricular block or bundle branch block .
92423751163>Overall , these findings demonstrate that mutations E768D and V804L are gain-of-function mutations that confer to the <n>long RET isoform</n> the capacity to exert a biological effect , although these mutations are more weakly activating than the <n>MEN2A</n> and <n>MEN2B</n> mutations .
88248057366>Several of the exon boundaries correspond to the boundaries of functional domains in the <n>p55 protein</n> .
86823174664>HS inducibility required the <n>HSE</n> which was bound by <n>HS transcription factor-1 ( HSF-1 )</n> present in extracts prepared from cells exposed to HS .
22256872861>Comprehensive care of the patient exposed to a human teratogen may also include discussion of prenatal diagnostic procedures and other pregnancy management options .
75089548825>The <n>avidin-biotin complex peroxidase</n> ( <n>ABC-P</n> ) method was used to detect Mycobacterium bovis , and the results were compared with those obtained by the Ziehl-Neelsen ( ZN ) technique .
89503528902>Therefore , both the Chilean and the Japanese samples collected in high-risk areas showed higher mutagenic rates than the Japanese ones in a low-risk area , with a statistical significance ( p < 0 . 001 ) , chi-square test ) .
54451875546>Counter-current heat exchange in the respiratory passages : effect on water and heat balance .
86361498288>Both mutant receptors were expressed on the cell surface and bound <n>insulin</n> normally , but showed markedly impaired autophosphorylation in response to <n>insulin</n> .
74500313336>Marked sedative activity was observed with 9-methoxy-5-phenylpyrrolo [ 2 , 1-d ] [ 1 , 5 ] benzothiazepin-6 , 6-dioxide ( NF19 ) and 9-chloro-5-p-nitrophenylpyrrolo [ 2 , 1-d ] [ 1 , 5 ] benzothiazepin-6 , 6-dioxide ( NF20 ) .
23241044455>A second , novel <n>C subunit</n> ( <n>CeCAT alpha'</n> , 374 residues ) has a unique 56-residue carboxyl-terminal region that is generated by the alternative splicing of the <n>C pre-mRNA</n> .
92611781026>The mouse <n>extracellular signal-regulated kinase 2 gene</n> .
13534781155>Interaction of <n>H-2Eb</n> with an <n>IAP retrotransposon</n> in the A20 / 2J B cell lymphoma .
100514005468>The <n>Lp mouse mutant</n> provides a model for the severe human neural tube defect ( NTD ) , cranio-rachischisis .
111583268689>These effects were not seen with <n>SHIP2</n> possessing a mutation in the <n>SH2 domain</n> ( <n>R47G</n> ) .
85520863174>We have identified and characterized a <n>vitamin D response element</n> ( <n>VDRE</n> ) in the promoter of <n>c-fos</n> .
22650552903>Plasma concentrations of atracurium and laudanosine were 0 . 73-3 . 11 micrograms ml-1 and 0 . 48-8 . 65 micrograms ml-1 , respectively ; CSF concentration of laudanosine was 70-440 ng ml-1 .
90422698997>These findings suggest that intraarterial neoadjuvant chemotherapy should be effective on advanced cervical cancer .
84081943937>Distinguishing roles of the membrane-cytoskeleton and <n>cadherin</n> mediated cell-cell adhesion in generating different <n>Na+ , K ( + ) -ATPase</n> distributions in polarized epithelia .
78916856905>These results suggest that gluconeogenic genes are derepressed upon binding of <n>Cat8p</n> , whose synthesis depends on the release of <n>Cat4p</n> ( <n>Mig1p</n> ) from the <n>CAT8 promoter</n> .
85230318494>We failed to find these data to be useful in predicting the time of onset of initial seizures after acute ischemic stroke and recurrence .
97927146492>The interaction of <n>AF-1</n> with proteins that regulate distinct steps of transcription may provide a mechanism for synergistic activation of gene expression by <n>AF-1</n> .
114186624973>The N-terminal portion of <n>Notch ( IC )</n> inhibited <n>p50</n> DNA binding and interacted specifically with <n>p50 subunit</n> , not <n>p65</n> of <n>NF-kappaB</n> .
29073083609>2 cases of type II tyrosinosis ( Richner-Hanhart syndrome ) .
22374317605>Expression of the human <n>T cell receptor ( TCR ) alpha gene</n> is regulated by a T cell-specific transcriptional enhancer that is located 4 . 5 kilobases ( kb ) 3' to the <n>C alpha gene segment</n> .
13746881985>Each group received 15 ml / kg of either 6% pentafraction , 6% pentastarch , or plasma followed two hours later by 1 . 5 micrograms / kg / 0 . 5 hr E .
9499048536>Infectious mutant virus progeny was obtained only on complementing gK-expressing cells , suggesting that <n>gK</n> has an important function in the replication cycle .
77063073253>The amino acid sequence of the protein in the region of the specificity pocket is similar to that of <n>S . griseus proteases A , B , and</n> C .
7600111309>The prevalence and incidence of human immunodeficiency virus types 1 and 2 ( HIV-1 , HIV-2 ) , human T-lymphotropic virus types I and II ( HTLV-I / II ) , and syphilitic infections and the association between these infections were determined in a cohort of police officers in Guinea-Bissau .
7556717442>As expected , the heparin did produce increased recalcification times and the development of occasional subcutaneous hematomas .
80754217325>The partial ORF was found to be identical to the C terminus of <n>HrpJ2</n> .
93714313652>Expression of <n>thiamin biosynthetic genes</n> ( <n>thiCOGE</n> ) and production of <n>symbiotic terminal oxidase cbb3</n> in Rhizobium etli .
109873017992>In this regard , we have recently observed that a constitutively active <n>G protein-coupled receptor</n> ( <n>GPCR</n> ) encoded by the Kaposi's sarcoma-associated herpes virus ( KSHV ) / human herpes virus 8 is oncogenic and stimulates angiogenesis by increasing the secretion of <n>vascular endothelial growth factor</n> ( <n>VEGF</n> ) , which is a key angiogenic stimulator and a critical mitogen for the development of Kaposi's sarcoma .
44606924977>Selected topics in laboratory animal medicine .
38270714505>II .
80839983878>These results suggest that leader-mRNA fusion in coronavirus transcription does not require direct RNA-RNA interaction between complementary sequences .
109405532870>These regions may be differentially involved in tissue-specificity , and / or circadian regulation , of the <n>human hPer1 gene</n> transcription .
2409297649>Polyclonal antiserum generated to the fusion protein was capable of detecting 42- and 46-kilodalton polypeptides from virus particles ; both polypeptides were also shown to contain <n>HBsAg determinants</n> .
116002527193>The LA 50s derived from this combined data when compared with our earlier series from 1965 to 1970 also did not show a significant change in mortality .
114474901325>The amount of drained effusion was measured , and fluid was sent for diagnostic assessment .
104955739584>Since sildenafil came on the market , it seems that the place of MUSE is reduced because comparative studies give better results for sildenafil than MUSE ( 70% vs 40% ) and of course with a better acceptance .
71555796974>Asymptomatic bacteriospermia and fertility .
80067738000>There was no difference in plasma concentrations of PGI2 ( figure 4 ) and TxA2 in patients with normal blood pressure , mild preeclampsia and hypotension , whereas in severe preeclampsia , the plasma concentration of PGI2 was significantly lower ( p < 0 . 001 ) and of TxA2 significantly higher ( p < 0 . 001 ) .
49256175241>Labial bar .
28752243570>Reperfusion with normal blood in the beating , working hearts caused extensive structural damage , reduced reflow , and failed to restore contractility in any instance ( -27% systolic shortening , p less than 0 . 05 ) .
29060277852>By sequence comparison , 42 blocks of homology are defined in the 5'-terminal region , of which 36 appear in the CpG island and contain numerous conserved CpG dinucleotides .
75426164314><n>GCD10</n> was first identified genetically as a translational repressor of <n>GCN4</n> .
95991028728>Analysis of a <n>Mac1p mutant</n> , refractile for copper-dependent repression of the <n>Cu ( I ) transport genes</n> , showed an aberrant pattern of <n>CUP1</n> expression and copper sensitivity .
2325208984>French , M .
92113546338><n>Stromelysin-1</n> , <n>matrix metalloproteinase-3</n> ( <n>MMP-3</n> ) , is an important <n>endopeptidase</n> selectively expressed by somatic cells in organ tissues .
71133658524>Ficat and Bizou's condylar depth index and the condylar-joint surface angle of Brattstrom are recommended as especially suitable methods of measurement .
27815673477>A soap and water ( 1 : 1 , v / v ) solution effectively decontaminated powdered stratum corneum .
82939924530>Each repeat consists of 12 nt , coding for the reiterated sequence , <n>K / NPAG</n> .
95142726738>Purification of <n>MvaT</n> enriched for two polypeptides of approximate molecular mass 15 kDa and 16 kDa , designated <n>P15</n> and <n>P16</n> .
101962664038>The Asian mouse Mus castaneus is resistant to infection by the polytropic mink cell focus-inducing ( MCF ) subgroup of murine leukemia viruses ( MuLVs ) .
106207771934><n>AB004534</n> .
17143585175>The 10 kDa polypeptide was phosphorylated in vitro by incubating wheat etioplast membranes with [ gamma 32P ] ATP .
99232452420>The RMRI was tested for interrater reliability using three simulated and 10 actual patients .
67959716565>The rat incisor is an excellent model system in which to study amelgenesis .
25719246210>Haploid cells of mating type A of the basidiomycetous yeast Rhodosporidium toruloides secrete a mating pheromone , <n>rhodotorucine A</n> , which is an undecapeptide containing S-farnesyl cysteine at its carboxy terminus .
90426832593>The FBF questionnaire did not highlight a characteristic basic symptoms profile of schizoaffective disorder , when compared with bipolar affective disorder and schizophrenia .
1003584133>Magnetic trapping of spin-polarized atomic hydrogen .
110902725621>The transcription and alternative splicing of <n>human ORL1</n> and <n>GAIP</n> are cell-type specific .
115338631408>In the single case the restoration of a structured daily routine represents the presupposition for a cognitive therapy .
96332749606>Exercise training has become increasingly important in the treatment of heart failure patients .
10443990289>BACKGROUND : Chronic alcohol consumption has been demonstrated to be deleterious to bone health .
91214541625>The similar phenotypes of <n>bur6</n> and <n>bur3</n> ( <n>mot1</n> ) mutations suggest that <n>Bur6p</n> and <n>Mot1p</n> have related , but not identical , functions in modulating the activity of the general transcription machinery in vivo .
86452148324>Escherichia coli BL21 ( DE3 ) plysS , harbouring a recombinant plasmid containing the <n>catalase-peroxidase gene</n> , produced a large amount of proteins that co-migrated on SDS / PAGE with the native enzyme .
83894538400><n>Uracil DNA glycosylase</n> catalyzes the initial step in the repair pathway that removes potentially mutagenic uracil from duplex DNA .
89550718747>Disruption of re-replication control by overexpression of <n>human ORC1</n> in fission yeast .
112782901635>Whereas <n>Smad2</n> was rapidly phosphorylated by <n>TGF-beta</n> and involved in the initial activation of <n>Agc</n> expression in confluent cells , <n>Smad2</n> activation was not required for maintaining the high level of <n>Agc</n> expression .
89366408893>DATA SOURCES : Epidemiologic studies , research studies , review articles , and government reports pertaining to epidemiology of lung cancer .
88721627547>Both alleles are functionally expressed and are distributed within <n>CD4+ / CD8+</n> T cell subsets .
18513862449>The Italian Lung Cancer Task Force ( FONICAP ) .
6225566029>These show that the <n>collagen</n> in this tissue is modified compared with that in tendon .
96502994317>Taken together , these data indicate that the <n>VirD2 omega domain</n> is important for efficient T-DNA integration .
95159211254>The spontaneous mutation blocking <n>pca gene</n> expression was located in the promoter for the <n>pca operon</n> .
83763978469>The binding specificity of this protein was compared to that of <n>human E2F</n> using a number of <n>mutant E2F sites</n> as competitors .
25087266567>These case reports provide further evidence that LiCO3 can be a useful medication in the treatment of aggressive behavior and affective instability after brain injury , but that it has significant potential for neurotoxicity in this population , particularly when used in conjunction with neuroleptic agents .
75890695815>We also isolated two alternatively spliced forms of <n>human CD6 cDNA</n> lacking sequences encoding membrane-proximal regions of the cytoplasmic domain which maintain the same reading frame as <n>CD6-PB1</n> .
11597936551>Eight CAD patients who were matched to the treated patients for age ( + / -3 years ) , baseline <n>low density lipoprotein</n> ( + / -5 mg / dL ) , and triglycerides ( + / -50 mg / dL ) but who had never been treated with lipid-lowering drugs were selected as controls .
101198274099>Judge OKs docs' bid for Chicago hospital .
87984203025>The characterization of the promoter region indicated that three distinct regulatory elements corresponding to an <n>AP-1 binding site</n> ( or <n>TRE</n> ) , a <n>PRDII / kappaB domain</n> , and a CAAT box are involved in the activation by <n>pp60 ( v- ) src</n> .
13333176456>The -64 / -37 region interacted with purified <n>Sp1</n> and an unidentified protein ( s ) , <n>proximal regulatory factor ( s ) I</n> ( <n>PRF-I</n> ) .
77003617082>Although most <n>SH2-pTyr</n> interactions occur between two different types of molecules , some appear to involve only a single molecular type .
23078506952>From an RNK-16 lambda-gt11 library , we have isolated and sequenced a novel cDNA <n>rat NK cell protease 1</n> ( <n>RNKP-1</n> ) that has characteristics unique to <n>serine proteases</n> .
78658888760>Similarly , in mammalian cells <n>PBP74</n> is synthesized as a pre-protein that requires membrane potential-dependent import into mitochondria for its maturation .
38249086876>The <n>M reading frame</n> differed from the reported sequence by a single nucleotide corresponding to a conservative lysine to arginine amino acid substitution near the carboxy-terminus conserved among the <n>M proteins</n> of paramyxoviruses .
85856392542>Occupational exposure to hepatitis B virus and human immunodeficiency virus : a comparative risk analysis .
26514873328>Although it is well known that calcium channel blockers can influence contraction of vascular smooth muscle , there is less knowledge on its effect on excitation contraction coupling in the endocrine glands and more specifically on <n>insulin</n> and glucagon release .
110580084700>There were no instances of major flap necrosis although two flaps showed tip ischaemia .
57633473769>Clinical applications of inhibition of <n>beta-adrenergic receptors</n> with propranolol .
87831808772>Improved methods have been developed for maintaining and breeding the neotropical short-tailed fruit bat , Carollia perspicillata , in an easily-reproduced , laboratory setting .
29992673342>The intensity of myocardial uptake of Tc-99m-PYP in patients with echocardiographic left ventricular hypertrophy and / or highly refractile myocardial echoes , so-called granular sparkling appearance ( GS ) was slightly greater than that in patients with neither myocardial hypertrophy nor GS .
119170611831>The only predictor of response to tacrolimus was a previous response to cyclosporin and prednisone , either as a complete or partial remission ( remission rate 75% vs 15 . 3 ; P = 0 . 036 ) .
83948628359>Three group 1 patients developed CMV disease ; 1 group 2 patient developed CMV hepatitis .
98693569857>CAL gain amounted to 4 . 2+ / -1 . 3 mm , 60% of the defects showing CAL gain > or = 4 mm .
66537555314>After clofelin administration the autoregulation borders shifted to the right i . e . towards higher AP levels .
35909114252>Persistent acantholytic dermatosis with increased light sensitivity .
10490662532>In fact , <n>SPT</n> activity in the fly expressing epitope-tagged <n>Lace</n> was absorbed by epitope-specific antibody .
8900282187>The length scales of the turbulence were also estimated : at a Reynolds number near 4 , 000 the macroscale is about 1 . 25 mm , the Taylor microscale is about 0 . 85 mm , and the Kolmogoroff scale is near 0 . 075 mm .
94202513225>C .
119103101821>DESIGN : Prospective , randomized , double-blind , controlled trial .
100377746403>In this study , we investigated the signal transduction pathways that are involved in OM-induced <n>LDLR</n> transcription .
30184911310>The <n>hexanucleotide 5'-TGTCCT-3'</n> , thought to be important for <n>GRE</n> activity , not only was found in this sequence and in the 5'-flanking region , but also was present twice in the 3' end of the gene that did not show specific receptor binding .
77488487711>The term endovascular papillary haemangioma is suggested .
8389074598>Mutations at the extreme C-terminus of <n>EIAV Tat</n> impaired both RNA binding and activation domain functions , suggesting effects on secondary or tertiary structure .
13601807745>Repeated efforts to isolate recombinant baculoviruses containing a <n>wild-type kinase</n> failed , whereas recombinants expressing a nonfunctional <n>kinase</n> with a catalytic <n>domain II</n> mutation were readily isolated .
79648148997>Elementary visual hallucinations in migraine and epilepsy .
100727748882>RT-PCR was performed using previously reported degenerate oligonucleotide primers to the ligand binding domain ( LBD ) of known <n>beta integrin subunits</n> and <n>Bge cDNA</n> .
33789945589>Chronic administration of sodium cyanate decreases O2 extraction ratio in dogs .
105185616725>Efficient phosphorylation of <n>BRDG1</n> by <n>Tec</n> required the <n>PH</n> and <n>SH2 domains</n> as well as the kinase domain of the latter .
113143731158>Evidence-based care : a new formula for an old problem ?
105997277565>With this <n>GH</n> and estrogen treatment regimen , most girls with TS can grow and develop much more in conformity with their healthy peers .
70215054315>After acclimation , resting supine and sitting DPB decreased ( P less than 0 . 05 ) by 6 and 9 mmHg , respectively .
8719697358>METHODS : DSF was instilled in one eye chosen at random and CF in the fellow eye of 13 normal subjects and in 13 patients with KCS .
105505748646>With regard to nonhematologic toxicities , diarrhea , infection and elevated <n>serum alkaline phosphatase</n> of grade 3 or over were observed in 2% of cycles , but were tolerable and reversible .
18710332477>Tests showed that an overall impression of the force applied could be obtained from a laboratory simulation , but that clearing cement and testing cement were not modelled by this method .
83242808303>These lesions were asymptomatic , but both were characterized clinically by central ulceration .
89788178478>In addition , double mutants with either <n>dim1-delta</n> or <n>dim2-1</n> and the endocytosis <n>mutants end4-1</n> or <n>act1-1</n> displayed synthetic growth defects , indicating that the <n>DIM gene products</n> function in a common or parallel endocytic pathway .
40323499745>35 patients with acute arterial occlusions [ 27 ] and graft thromboses [ 8 ] , responsible for severe and recent ischemia , were treated by fibrinolytic therapy ( <n>Urokinase</n> : 1 000 units / kg / hour , and Lys <n>Plasminogen</n> ) .
95355793458>Moreover , it is the assumptions behind steady-state O2 uptake that do not permit proper interpretation of energy expenditure during EPOC ; 1 l O2 not = 20 . 9 kJ .
24065701346>An examination of the properties of sequences surrounding <n>ARS1</n> left open the possibility that <n>ABFI</n> enhances the initiation of DNA replication at <n>ARS1</n> by transcriptional activation .
104670043521>The intron is capable of splicing despite the fact that both the <n>EBS1 / IBS1</n> and the <n>EBS2 / IBS2 sequence motifs</n> , thought to be necessary for correct splicing , extend over 5 instead of 6 bp .
76168027527>From day 10 , a significant increase in platelet count was observed in eight of the ten patients treated with heparin ( p < 0 . 05 ) , with return to the initial value after heparin cessation in six of the responders .
76670979683>The association of <n>p255</n> with splicing complexes is suggested by the finding that <n>mAb CC3</n> can inhibit in vitro splicing and immunoprecipitate pre-messenger RNA and splicing products .
13272801958>In rats anaesthetized with +-chloralose the changes in extracellular pH and K+ in spinal cord dorsal horn were studied using pH and K+ ion-selective electrodes .
98069199199>Rather , <n>usp</n> is required in late third instar larvae for appropriate developmental and transcriptional responses to the ecdysone pulse that triggers puparium formation .
1227186354>The majority of MRF units were behaviorally incongruent ; in the most frequently observed case , their activity failed to change reliably when behavior habituated .
76047837503>There were no significant changes in either the fatty acid composition of biliary lecithin or in the bile acid composition of bile .
95817751509>In the present study , we sought to investigate whether <n>constitutive NF-kappaB</n> activity in chronically HIV-1-infected promonocytic U937 ( U9-IIIB ) and myeloblastic PLB-985 ( PLB-IIIB ) cells affects apoptotic signaling .
62908998700>Survey on antibody against egg drop syndrome-1976 virus among chicken flocks in Japan .
106791901639>We present evidence that the upstream open reading frame ( uORF ) represses the translation of the downstream major open reading frame ( mORF ) .
104632423534>In EEG only single slow waves above left temporal region were revealed .
118258011694>No increased tumor-related mortality was observed after a mean follow-up of 44 months .
26483967663>In Rat-1a cells the expression of <n>human c-jun mRNA</n> was associated with the ability to clone in soft agarose and form tumors in nude mice .
74900839207><n>Carbonic anhydrase V</n> ( <n>CA V</n> ) is expressed in mitochondrial matrix in liver and several other tissues .
80956981830>Metabolism of calcium and vitamin D3 in patients with acute tubulointerstitial nephritis : a study of 41 patients with nephropathia epidemica .
114060251269>OBJECTIVES : The objective of this review was to compare the effectiveness , safety and acceptability of the diaphragm with and without spermicide .
88074083961>METHODS AND RESULTS : A 64-year-old woman with confirmed AV nodal reentrant tachycardia underwent a successful "slow pathway" AV modification with a single radiofrequency application .
87469818732>In 3 treatments the diet was supplemented with 0 , 100 and 150 mg probiotic / kg food .
74998485442>We show that stimulation of resting splenic B cells with CD40L-expressing Sf9 cells induces germ-line <n>gamma 1</n> and <n>epsilon transcripts</n> independently of cytokines .
96213727874>Routine blood examination showed leukocytosis , thrombocytopenia , positive <n>CRP</n> , and elevated myocardial enzymes .
74344317303>We propose that refeeding may be an important mechanism for activation of certain viral infections previously suppressed by famine .
78920768370>Survival after development of symptomatic infection ( P-2 ) did not differ by transmission mode .
1002749817>Most other end points were highly significant , and death , which was monitored across the U . S . program , was different with p < 0 . 0001 .
79427227917>Constipation is not a risk factor for hemorrhoids : a case-control study of potential etiological agents .
82082474484>Mutational analysis of chromosomal segment 64AB , a region containing the <n>glutamic acid decarboxylase gene</n> .
13581902796>Substitution of the <n>DR1 beta chain</n> with <n>H-2E beta k</n> led to a dramatic loss of recognition ; alpha chain substitution had a less marked effect .
86184333355>In contrast to the selective expression of the receptor , <n>FL</n> expression was detected in 90-100% of the various cell types of leukemia cell lines from all hematopoietic cell lineages .
77903779232>Antibodies to the <n>human PTS1R</n> recognize this protein in human , monkey , rat , and hamster cells .
9685346627>The combination of <n>Pitx2</n> and another <n>homeodomain protein</n> , <n>Pit-1</n> , yielded a synergistic 55-fold activation of the <n>prolactin promoter</n> in transfection assays .
110350084516>Consistent with the specificity observed for the interaction of <n>DmCKIIalpha</n> with these <n>bHLH proteins</n> , sequence alignment suggests that only <n>m5</n> , <n>m7</n> , and <n>m8</n> contain a consensus site for phosphorylation by <n>CKII</n> within a subdomain unique to these three proteins .
86549465456>The transcription start point of the proximal promoter aligns to that of <n>mouse promoter P3</n> and lies within a conserved region of sequence .
11154491990>METHODS : One hundred fourteen consecutive patients ( mean age 61 years ) with focal pancreatic masses , detected on CT , underwent EUS-FNA by using a linear-array echoendoscope and 22-gauge needles .
83476774007>The phosphorylation efficiency is improved by increasing the number of N-terminal arginine residues and by moving the arginyl cluster one residue further away from the serine , the <n>nonapeptide ( Arg ) 4-Ala-Ala-Ser-Val-Ala</n> being the best substrate among all the short peptides tested ( Km = 15 microM ) .
118836821774>Here is presented the monitoring of the accidental spill on vertical distribution of heavy metals in the estuarine sediments .
82893427513>A mutant in the AAV terminal resolution site ( trs ) was defective for DNA replication in the in vitro assay .
90914035168>Analysis of homologous DNA sequences within the first intron of the <n>mouse and human mts1 genes</n> : <n>kB-like site</n> and microsatellite DNA .
93411588848>The medium chains of these complexes , <n>mu1</n> and <n>mu2</n> , have been implicated in two types of interaction : assembly with the <n>beta1 and beta2 chains</n> of the corresponding complexes and recognition of tyrosine-based sorting signals .
14003968874>The promoter was stimulated 8-20-fold by phorbol esters accounting for the previously observed transcriptional activation of <n>protein kinase C beta</n> .
37615234427>The rats were used for the study of the effects of sepsis on the utilization of exogenous fat emulsion .
98065469631>Its interaction with <n>RFX5</n> and <n>RFXAP</n> is essential for binding of the <n>RFX complex</n> to <n>MHC-II promoters</n> .
76238144143>In CV-1 cells , cotransfection of the <n>retinoid and estrogen receptors</n> led to mutual inhibition of the other's activity , while an RA-dependent inhibition of <n>ER</n> activity was observed in breast cancer cells .
21186122718>Thirty minutes of supine restraint decreased DOPAC concentrations in the median eminence of female rats that were not exposed to ether , and brief exposure to ether enhanced this effect .
102214672779>Constrictive pericarditis and pleuropulmonary disease linked to ergot dopamine agonist therapy ( cabergoline ) for Parkinson's disease .
19990352613>The first follow-up was at a nearly constant interval of 5 . 1 years in Caerphilly and 3 . 2 years in Speedwell ; 251 major IHD events had occurred .
87943487445>A transgenic complementation assay was used to test whether <n>NIa</n> supplied in trans could rescue amplification-defective viral genomes encoding altered <n>NIa proteins</n> .
100002532>Chirality-glass and spin-glass correlations in the two-dimensional random-bond XY model .
84556231787>Initial results indicate that this <n>23S pre-rRNA</n> is the same as the species detected on depletion of the <n>small nucleolar RNA-associated proteins NOP1</n>1 and <n>GAR1</n> and in an <n>snr10 mutant</n> strain .
89735272870>Complementary DNAs encompassing the <n>coat protein</n> coding and adjacent regions of Agropyron mosaic virus ( AgMV ) and Hordeum mosaic virus ( HoMV ) were cloned and sequenced .
8838314135>To understand further the expression and regulation of the <n>V1aR</n> , we now describe the genomic characteristics , tissue expression , chromosomal localization , and regional mapping of the <n>human V1aR gene</n> , <n>AVPR1A</n> .
80839999664>Vaccinia virus-expressed , purified <n>full-length HPV-16 and BPV-1 E2 proteins</n> bound a consensus <n>E2 site</n> with high specific affinities ( Kd = approximately 10 ( -9 ) M ) and stimulated in vitro transcription up to six- to eightfold .
9159183959>Genes for <n>ocs element binding factors</n> ( <n>OBFs</n> ) , belonging to a specific class of <n>basic-region leucine zipper ( bZIP ) transcription factors</n> , have been isolated in a number of plants .
103799421335>Interestingly , highly charged residues were abundantly possessed in the carboxy-terminal part of the <n>MDV2 UL10 protein</n> .
14096432539>By using lambda gt11 expression cloning with oligonucleotides corresponding to the human immunodeficiency virus 1 TATA element , we report the identification of a cellular protein with a calculated molecular mass of 123 kDa that we designate <n>TATA element modulatory factor</n> ( <n>TMF</n> ) .
76284516885>We show here that RA and <n>E1A</n> induce phosphorylation of the <n>E1A-associated 300 kDa protein</n> ( <n>p300</n> ) during the differentiation of F9 cells .
22572512896>Pathophysiology of bone loss in castrated animals .
28987523604>A strong correlation exists between the numbers of CFU-GM transfused and the rate of granulocytes and platelets recovery .
3003146875>Because of serious infections ( fever larger than or equal to 101 degrees F . granulocytes less than 1 , 000 / mm , 3 and hospitalization ) and 1 drug death in the first 4 patients , oral calcium leucovorin , 20 to 30 mg / m2 orally , was given 2 days after methotrexate in subsequent treatment cycles .
115131801391>Of the six cases of malignant polyposis , none were identified using CT , and only two were diagnosed by small bowel follow-through .
100376814655>Successful interaction of <n>ARF</n> and <n>PKC-alpha</n> with <n>PLD1</n> was not achieved , but a C-terminal fragment of <n>human PLD1</n> ( denoted "D4" ) interacted with the active mutant of <n>RhoA</n> , <n>RhoAVal-14</n> .
37803716656>Repetitive sequences are present in at least three introns of the <n>cytochrome P-450PBc2 gene</n> , but not in exons or the 5'-flanking region .
108622896035>( GUT ) Sera of 30 montoux negative healthy adults ( age / sex matched ) were taken as control by detecting <n>IgG anti bodies</n> to <n>A60 antigen</n> .
105415507338>Using immunolocalization , we observe that <n>ACE3</n> , a 440-bp chorion element that contains information sufficient to drive amplification , directs DmORC localization in follicle cells .
94884919176><n>E2F</n> activity is regulated in part by the <n>retinoblastoma family of tumor suppressor proteins</n> .
36155508908>The rate-decreasing effects of morphine and U50488 were reversed completely by a 0 . 01 and 1 . 0 mg / kg dose of naloxone , respectively .
41399435538>Demonstration of fine structure of the guinea pig organ of Corti after electron microscopic silver staining .
27890629109>A cDNA encoding the <n>NF-4FB enhancer binding protein</n> has been cloned by screening a lambda gt11 cDNA library with a rabiolabelled oligonucleotide corresponding to the <n>NF-4FB recognition sequence</n> .
96788372184>The aim of the study was to correlate the responsiveness to bronchoprovocation with methacholine in subjects a with allergic rhinitis during and out of the pollen season with total serum <n>IgE</n> and blood eosinophils .
108018602892>The <n>Siglecs</n> are a subfamily of <n>I-type lectins</n> ( <n>immunoglobulin superfamily proteins</n> that bind sugars ) that specifically recognize sialic acids .
95524699508>The interaction between piroxicam and poloxamer was studied by x-ray diffractometry ( XRD ) , infrared ( IR ) spectroscopy and differential thermal analysis ( DTA ) with a solid dispersion , coprecipitate , or physical mixture .
48903368759>Immunelectrophoretic pattern of Wassermann reagin and comparison of the appearance time between <n>RPCF</n> and <n>FTA antibodies</n> .
92518439213>Reactive lymphoid hyperplasia was found in 15 cases , 2 cases had angiofollicular lymphoid hyperplasia or Castleman's disease , atypical lymphoid hyperplasia suggestive of malignant lymphoma was observed in 3 cases , and malignant lymphoma was diagnosed in the remaining 4 cases .
95382586696>In this report , we investigate the mechanism underlying <n>Ras</n> activation upon stimulation of these two types of receptors in hematopoietic cells .
61383135959>The distribution phase is followed by an elimination phase with a much longer half-life ( mean value 375 min ) and a volume of distribution of approximately 200-400 l .
88434199408>OKA and calyculin A do not decrease <n>OCFRE</n> DNA-protein interactions , suggesting that important protein-protein interactions are phosphatase regulated .
105637897350>In addition , media containing <n>F beta alpha / CG beta</n> displayed high-affinity binding to both <n>CG</n> and <n>FSH receptors</n> .
90730746733>Antisense transcription of a <n>murine FGFR-3 psuedogene</n> during fetal developement .
3863561744>Within the Strep . mutans group there was a highly-significant difference between Strep . mutans / Strep . cricetus ( p less than 0 . 01 ) with respect to mean clump size .
10722969548>Here we review progress to date in this area .
26494453322>Both BG and <n>IRI</n> concentrations during the OGTT were the lowest in body builders , medium in controls , and the highest in obese men .
39671444615>Hypersplenism .
104589051512>We report the construction of an approximately 1 . 7-Mb sequence-ready YAC / BAC clone contig of 8p22-p23 .
96283759596>In the ePTFE specimens , tissue coverage had increased .
6180786000>A decrease of the <n>lysozyme</n> activity coincided with the clinical improvement of the bacterial meningitis .
100851207657>In this study , we elucidate signaling pathways induced by photodynamic therapy ( PDT ) with hypericin .
84633203753>In situ copper-phenanthroline footprinting of individual gel shift assembly intermediates shows that on the 302-nucleotide G4oric , the first two <n>SSB tetramers</n> assemble at random , but the addition of more <n>SSB tetramers</n> results in formation of a unique structure .
39221168890>The distribution of patients was as follows : group 1--complex gamma-therapy ( 55 cases ) , group 2--complex gamma-therapy plus iliac lymphadenectomy ( 50 cases ) and group 3--complex radiation treatment with megavolt bremsstrahlung beam from the luc type installation and iliac lymphadenectomy ( 50 cases ) .
91487703318><n>Cellular Csk</n> was associated with several phosphoproteins , some of which were interacting with the <n>Csk SH2</n>1 <n>domain</n>1 .
100965738516>Previous studies characterized a cytokine-inducible , functional <n>nuclear factor ( NF ) -kappaB consensus element</n> in the immediate 5' regulatory region of the <n>MGSA / GRO-alpha gene</n> at -78 bp .
90322546526>Enhancer activity requires both the <n>AP-1 site</n> and these adjacent sequences .
33437309522>A significant association between a family history and a higher urinary pH was observed among the female calcium stone patients .
50316591666>Successful treatment of candidiasis with transfer factor .
68584496657>Disturbances of placental maturation , 2 .
13780529000>Between <n>acoR</n> and <n>acoXABC</n> , two different types of sequences with dual rotational symmetry [ CAC- ( N11 to N18 ) -GTG and TGT- ( N10 to N14 ) -ACA ] were found ; these sequences are similar to <n>NtrC</n> and <n>NifA upstream activator sequences</n> , respectively .
11151826989>Workload , UAPs , and you .
113272921178>This unique location of cavernous malformation is associated with a risk of permanent loss of the vision .
103967939001>Results for men who drank up to two drinks per day suggest that if the dependence criteria were invalid , reductions in the prevalence of specific indicators of alcohol dependence would range from 0 . 3% to 5 . 2% .
92721382240>The complete response ( CR ) rate was 34% in the CODE with <n>rhG-CSF</n> group and 23% in the CODE alone group ; the median survival was 59 and 32 weeks , respectively , in these groups ( P = 0 . 004 ) .
87096376038>The data further indicate that the <n>IL-7R alpha chains</n> are directly involved in the activation of <n>JAKs</n> and <n>STATs</n> and have a major role in proliferative signaling in precursor B cells .
87225683990>Chromatin repression of these replacement genes would be avoided , consistent with the high , constitutive expression of replacement <n>H3 histone genes</n> in plants .
63106082784>The mutants were obtained by substitution into a molecular clone of M-MuLV DNA by DNA from two acutely transforming viruses , Ableson MuLV ( Ab-MuLV ) and Moloney murine sarcoma virus ( M-MSV ) .
77637277816>Plasmids pAMS12 , pAMS13 and pAMS14 were transformed into a laboratory strain of Saccharomyces cerevisiae , whereas pAMS15 was stably introduced into two commercial wine yeast strains .
31042484040>Within Stage IA , 141 patients had well differentiated tumor ( G1 ) , 20 had moderately well differentiated tumor ( G2 ) , and 12 patients had poorly differentiated ( G3 ) .
99313919927>Complete recovery of liver function after this surgery tended to be slow .
18695658847><n>USF</n> synthesized in an in vitro transcription and translation system also binds to the <n>ADH promoter</n> as well as to the MLP .
88514348826>In lean mice , the fat / water intensity ratio was about 1 : 4 , about half that in normal mice .
91645439112>MATERIAL AND METHODS : The authors analyzed 41 persons formerly submitted to surgery ( after 8 years and 4 months , as a mean ) , 31 to highly selective vagotomy , and 10 to truncal or selective vagotomy plus gastroduodenal drainage .
4547803248>Ultimate strengthes seem to be reached for cast cobalt alloys , whereas titanium alloys , such as Ta 6 V , present very high fatigue limit under corrosion .
98235619808>Low-grade gastric MALT lymphoma and helicobacter heilmannii ( Gastrospirillum hominis .
79267486093><n>NOT4</n> interacts with <n>NOT1</n> and <n>NOT3</n> in the two-hybrid assay , and overexpression of <n>NOT3</n> or <n>NOT4</n> suppresses <n>not1</n> and <n>not2</n> mutations .
28839639901>Six patients with human T-cell lymphotropic virus type I ( HTLV-I ) -associated myelopathy ( HAM ) were studied by electrophysiologic methods .
10891632715>The naltrexone / lofexidine combination was associated with a more rapid resolution of the opiate withdrawal syndrome than a 7-day lofexidine-only treatment schedule , without substantial increases in withdrawal symptoms or hypotensive side-effects .
21250167574>PBSX is induced by agents which elicit the SOS response .
97221614369>Regulation of embryonic growth and lysosomal targeting by the imprinted <n>Igf2 / Mpr gene</n> .
72353559831>Five control subjects with COPD , who performed the same sequence of tests without breathing 30% O2 , showed no change in flow rates or density dependence .
107560202850>The protein was associated with purified vaccinia virus particles and with membranes of immature and mature virions that were visualized by electron microscopy of infected cells .
78923535234>Both factors demonstrated significant correlations with rCBF in the medial prefrontal cortex and frontal polar cortex while for each factor there were also unique patterns of correlations with posterior brain regions .
84441844419>Sudomoina , A .
100971206966>An exon that prevents transport of a mature mRNA .
73859207221>The results revealed increased blood lead level associated with decreased <n>blood haemoglobin</n> and increased urinary excretion of delta amino levulinic acid .
95531435160>An in vivo <n>ZAP-70</n> substrate , <n>SLP-76</n> , implicated in <n>Erk</n> activation , also became rapidly tyrosine-phosphorylated in Jurkat cells , but not in P116 cells , upon treatment with H2O2 .
109651352356>Promoter activity was dose-dependently inhibited by cotransfection with either <n>ras</n> or <n>mos oncogenes</n> , but oncogene inhibition was reversed and the overall activity increased when cells were treated with the <n>MAP kinase kinase</n> ( <n>MKK</n> ) inhibitor PD98059 .
17386532320>Bone and bones .
80417939733>In earlier studies we identified several regulatory elements that control transcriptional activation and aerobic repression of one of these genes , <n>COX5b</n> .
85296628648>Furthermore , we have identified a soluble form of <n>ERp57 / GRP58</n> by Western blotting and biosynthetic labeling .
36882025749>The models accurately localized the common boundaries between the PBB and CN .
64732526279>This experiment was conducted to determine if the sex or actual egg production was the important factor . ( ABSTRACT TRUNCATED AT 250 WORDS )
37819484466>Respiratory adaptation to chronic hypoxia in newborn rats .
109381027096>Collectively , these and previously published data suggest a model where <n>NS1</n> recruits <n>eIF4GI</n> specifically to the 5' untranslated region ( 5' UTR ) of the viral mRNA , allowing for the preferential translation of the influenza virus messengers .
36782694341>Today there is no doubt that elevated plasma cholesterol levels should be lowered first by dietary modification even in early childhood , beginning at the age of two years .
98805431991><n>HEED</n> was found to bind to <n>MA protein</n> in vitro , as efficiently as in vivo in yeast cells .
109397852567>Patients were randomly assigned to treatment with the <n>ACE</n> inhibitor perindopril ( and the diuretic indapamide for those with no definite indication for or contraindication to treatment with a diuretic ) or matching placebo ( s ) .
57972875730>I .
79139262448>Northern analysis of RNA samples isolated from ammonium-grown cultures of the <n>ntcA mutant</n> showed reduced amounts of <n>glnA message</n> and the absence of a 1 . 7-kb transcript .
88361727427><n>RVR</n> 'loss of function' studies by constitutive over-expression of a dominant negative <n>RVR delta E</n> resulted in increased levels of <n>p21Cip1 / Waf1</n> and <n>myogenin mRNAs</n> after serum withdrawal .
984092838>Consistent with this , purified <n>Dlk</n> phosphorylated core <n>histones H3</n> , <n>H2A</n> and <n>H4</n> as exogenous substrates and endogenous <n>histone H3</n> in kinase assays with nuclear extracts .
53885675518>The effects of taloximine and aminophylline on isolated human smooth muscle .
21377042562>In a highly select group of stable hypertensive patients , we have assessed the strength of association between various blood pressure measurements ( 24 h average automated ambulatory blood pressure , 4 h automated ambulatory morning average blood pressure , multiple office visit average blood pressure , and a single office visit average blood pressure ) and various echocardiographic indices of hypertensive cardiac target organ damage ( left atrial diameter , left ventricular end diastolic diameter , posterior wall thickness , combined wall thickness , relative wall thickness , left ventricular mass and mass index , and combined wall thickness / left ventricular diastolic diameter ratio ) .
7607233120>The structural gene encoding the novel lantibiotic <n>epilancin K7</n> from Staphylococcus epidermidis K7 was cloned and its nucleotide sequence was determined .
104096568640>Overexpression of <n>H411 cDNA</n> in the RAW 264 . 7 macrophage cell line promoted an increased growth rate , suggesting that expression of <n>H411</n> is part of the proliferative cell response to LPS .
74153407269>Number and size of the myelin structures in the pneumocytes typ II increased simultaneously .
103667221833>cDNA and structural organization of the <n>gene Pole1</n> for the <n>mouse DNA polymerase epsilon catalytic subunit</n> .
26869858031>A transcription factor exclusion assay was used to show that the <n>PCF1 mutation</n> affects two distinct stages in transcription : one prior to and one after stable complex formation ; and that these effects are mediated by a component of the stable complex .
102234988559>Efficacy was determined by responses to question 3 ( ability to achieve an erection ) and question 4 ( ability to maintain an erection ) of the 15-item International Index of Erectile Function ( IIEF ) .
19671301292>The 1489-base pair <n>EFIA</n> cDNA encodes a 322-amino acid protein which is nearly identical to two previously described human DNA binding proteins .
95449913974><n>PRL receptor</n> also activates <n>SHP-2</n> , a <n>cytosolic tyrosine phosphatase</n> .
73230637184>Thirty-one age-matched , conscious , virgin , male Sprague-Dawley rats and spontaneously hypertensive rats ( SHRs ) were individually injected with a single subcutaneous dose of 85 mg / kg dl-isoproterenol to determine the degree and time course of drug-induced cardiac failure and functional recovery .
111399748849>Termination of induced VT on the first attempt was comparable with BV pacing ( 87 . 4% ) versus RV pacing ( 89 . 6% ) .
97907671>We mapped two overlapping expressed sequence tag clones within a genomic contig on human chromosome 5 , band q31 .
791754027>60 patients were entered into a randomised study comparing vindesine ( 3 mg / m2 / week ) plus <n>interferon-alpha 2b</n> ( 6 U / m2 3 times per week ) to vindesine alone or to <n>interferon</n> alone for the treatment of metastatic malignant melanoma .
96513834953>However , mutations in the <n>HNF-4 binding site</n> on <n>element CIIB</n> and inhibition of <n>HNF-4</n> synthesis in HepG2 cells by antisense <n>HNF-4 constructs</n> decreased the <n>apoCII promoter</n> activity to 25-40% of the control , indicating that <n>HNF-4</n> is a positive regulator of the <n>apoCII gene</n> .
114086047679>Our results indicate that <n>D ( 4 )</n> and <n>D ( 2L ) receptors</n> activate the <n>ERK kinase</n> cascade by first mobilizing signaling by the <n>PDGF receptor</n> , followed by the subsequent activation of <n>ERK1 / 2</n> by pathways associated with this <n>receptor tyrosine kinase</n> .
34034124100>The effects of anabolic implants on rate , composition and energetic efficiency of growth were determined in steers fed diets varying in forage and grain content .
10349443205>The results of the lab and field tests yielded high levels of infestation in larvae with values ranging from 90 to 100% and from 85 to 95% , respectively .
97380103472>The <n>FAS promoter</n> was up-regulated by <n>insulin</n> through the proximal <n>insulin response sequence</n> containing an E-box motif at the -65-base pair position .
90675778631>In cell lines transformed by <n>BCR / ABL</n> , <n>CRKL</n> was tyrosine phosphorylated , while <n>CRK</n> was not .
106626144046>The two-hybrid assay was then performed using full-length genes of <n>CI</n> , <n>HC-Pro</n> , <n>P1</n> , <n>P3</n> , and <n>CP</n> , but no heterologous interactions were detected .
313734666>The <n>nucleolin gene</n> extends over 9000 base-pairs and is split into 14 exons that encode the 706 amino acid residues of the protein .
54638379257>The absolute configuration at C-2 in monocrotalic acid .
13571902450>With the exception of mutants that remove the membrane anchor domain , all of the mutant glycoproteins retained the ability to cause fusion of CD4-bearing cells .
95030178674>We also present evidence that <n>human HYAL1</n> is identical to an uncharacterized gene positionally cloned by others from chromosome 3p21 . 3 that is homozygously deleted in several small-cell lung carcinoma cell lines .
86681584110>Furthermore , strains with <n>mutant RPM1 genes</n> also accumulate <n>precursor Rpm1r</n> , suggesting that mutations in either gene can lead to similar biogenesis defects .
114166501288>Isolated Systolic Hypertension : An Update .
89184644671>STK / RON-expressing Ba / F3 pro-B cells ( BaF / STK ) exhibited MSP-dependent growth , whereas <n>STK /</n> RON-expressing mouse erythroleukaemia cells ( MEL / <n>STK</n> ) displayed MSP-induced apoptosis .
30976439999>Also , the <n>BALB / c gene</n> contains a single substitution in a conserved octamer sequence approximately equal to 100 nucleotides upstream of the coding region , which could affect its expression .
98847476758>Immunological testing was performed on all brewery workers and some control volunteers using skin prick testing with hops , barley , and yeast antigens as well as other nonoccupational allergens , and by determining total <n>serum IgE</n> levels .
76165633784>Purified <n>CarP</n> binds in vitro to the <n>carAB control region</n> and protects against <n>DNase I</n> two approximately 25 bp long stretches , one of which is located just downstream of the <n>GATC sequence</n> .
98077559633>An intact neurovascular supply is essential for the viability of a muscle flap .
41891587201>Prevention of maternal Rh sensitization : <n>anti-Rh immune globulin</n> .
10704196275>The pCMBS-reactive sulfhydryl groups were located exclusively in the exofacial half of the plasma membrane and , when presented in a helical model , lie along one side of the helices .
30651409350>These mutations alter two regions of <n>GAL4 protein</n> : the DNA binding domain , and the transcription activation domain .
99867965897>However , deletions of the C terminal 11 or 14 amino acids had more substantial effects .
23474077559>In the local geomagnetic field , the animals preferred the SE-sector .
96386508100>It contains a 5'-noncoding region ( NCR ) of 73 nucleotides , five open reading frames ( ORFs 1 to 5 ) which encode proteins with M ( r ) <n>160 kDa RNA-dependent RNA polymerase ( ORF1 )</n> , <n>26 kDa movement protein 1 ( ORF2 )</n> , <n>13 kDa movement protein 2 ( ORF3 )</n> , <n>10 kDa movement protein 3 ( ORF4 )</n> , <n>24 kDa coat protein ( OFR5 )</n> , and a 3' NCR of 76 nucleotides .
115351401410>Audiological findings in pregnancy .
29205915219>Hemodynamic assessment was obtained before and following administration of digoxin 10 micrograms / kg IV or dopamine , 5 to 12 micrograms / kg / min IV .
68588056660>Both groups were subjected to tests of delayed hypersensitivity with Candidin , Trycophytin and Tuberculin .
79572439715>Notably , these residues are located in different domains .
92576511653>The human <n>U4 / U6 snRNP</n> contains 60 and 90kD proteins that are structurally homologous to the yeast splicing factors <n>Prp4p</n> and <n>Prp3p</n> .
96696412751>The diagnostic accuracy of serum <n>PE-1</n> was 0 . 80 , and that of <n>amylase</n> 0 . 97 .
3297181450>Six healthy male subjects received single oral doses of regular release ( RR ) quinidine sulfate , sustained release ( SR ) quinidine bisulfate and the same dose of the SR product with food ( SR-F ) .
24549762404>We discuss the results in relation to previous systems for parcellating the posterior ectosylvian gyrus of the cat and consider the possibility that divisions of the feline posterior ectosylvian gyrus correspond directly to areas making up the superior temporal gyrus in primates .
9771555555>The results indicate that anthraquinone sennoside B and rhein are weakly genotoxic .
1036714229>Studies of biochemical and morphological changes ( between normal and treated animals ) show that chrysotile induces an increase in the lung free cell population and pulmonary surfactant levels .
10226838166>The motility of sperm , except for those adjacent to both electrodes , did not change after stimulation for 60s , despite a high electrical energy .
91152473079>11-Aminoundecanoyl-SK-NH2 and 11-aminoundecanoyl-SH-NH2 establish that a simple alkyl backbone can maintain an appropriate distance between three elements critical for recognition by the fungal enzyme's peptide-binding site : a simple omega-terminal amino group , a beta-hydroxyl , and an epsilon-amino group or an imidazole .
113027044842>Homo-oligomerisation and nuclear localisation of <n>mouse histone deacetylase</n> 1 .
75927233535>Phorbol esters stimulated phosphorylation of <n>CSK 35H proteins</n> , thus emphasizing that sequences isolated according to <n>PKC</n> binding activity in vitro are also <n>PKC</n> substrates in vivo .
43257364933>Serodiagnosis of ectromelia in laboratory mice .
97161835512><n>TBP</n> can be phosphorylated in vitro by extracts of U937 cells or by bacterially expressed activated <n>ERK2</n> ; the phosphorylation sites were mapped to <n>ERK kinase consensus sites</n> in the <n>TBP amino-terminal domain</n> .
81249568092>Sodium-taurocholate-induced acute necrotizing pancreatitis does not affect jejunal oxygenation in pigs .
97476519729>Laser ablation has been employed as a therapeutic measure for chronic pulmonary emphysema .
17819239495>This differential sensitivity to DB , as measured by a lower concentration of DB which caused loss of righting in LS , was accompanied by an equal rate of water-soluble barbiturate brain distribution and elimination in the two lines .
87942541158>In the SPK and PTA category , anti-T-cell therapy significantly lowered the risk of graft loss .
6233616033>Smoking was regarded as the major contribution to pulmonary dysfunction .
111396051726>Deletion analysis showed that the -321 / +41 sequence was sufficient for both the constitutive promoter activity and auto-activation and electrophoretic mobility shift assays identified the interaction of <n>C / EBPs</n> and <n>Sp1</n> to this region .
78483581100>A reduction of the <n>aspartate aminotransferase</n> activity was observed from 800 mg / kg b . w . / d onwards .
113278583106>Through two novel mechanisms , <n>Arf</n> inhibits the <n>oncoprotein Hdm2</n> , a negative regulator of <n>p53</n> .
22201028789>Incidence correlated with the grade of oral hygiene und periodontal disease .
87943638398>On the basis of its <n>bZIP</n> structural homology , <n>meq</n> is perhaps the only member of the <n>jun-fos gene family</n> completely viral in origin .
76059903272>Although further studies are required to determine the precise role of <n>PEBP2</n> in the <n>GM-CSF promoter</n> activity , the present findings suggested the importance of the relative ratio of different <n>PEBP2 isoforms</n> in regulating the levels of the promoter activity .
104136763381><n>FAK</n> localizes to sites of <n>transmembrane integrin receptor</n> clustering and facilitates intracellular signaling events .
99900604037>In concert with the coactivator <n>CREB binding protein / p300</n> , which interacts with <n>GABPalpha</n> , the binding of <n>GABPalpha and -beta</n> to the dyad symmetry element controls the induction of <n>IL-16 promoter</n> in T cells .
86178003594><n>DNase I</n> footprinting and electrophoretic mobility shift assays indicate that <n>PBP</n> binds to the half-site of each palindrome with the <n>core recognition sequence TGGGAG</n> .
31862703880>You make the diagnosis .
108783983526>In hemodialyzed patients ( <n>Epo</n> and Non-Epo group ) <n>leptin</n> levels were significantly higher when compared to CAPD patients ( <n>Epo</n> and Non-Epo group , respectively ) .
56729035637>Osteogenesis imperfecta .
36089892880>This region of 60 amino acids may be involved in coiled-coil interactions similar to those that facilitate the filament formation in the rod region .
68082877659>Detection of hemophilia A carriers .
97053246151><n>DNase I</n> footprinting and electrophoretic mobility shift analyses revealed two <n>hepatocyte nuclear factor-1</n> ( <n>HNF1</n> ) , three <n>CCAAT / enhancer-binding protein</n> ( <n>C / EBP</n> ) , and one consensus palindromic <n>thyroid hormone response elements</n> within the first 215 base pairs ( bp ) of the promoter sequence of <n>rat Std</n> .
15511769830>GR63178A is a water-soluble analogue of mitoquidone , a pentacyclic pyrroloquinone .
97106144183>Identification of a proline-rich sequence in the <n>CD2 cytoplasmic domain</n> critical for regulation of integrin-mediated adhesion and activation of <n>phosphoinositide 3-kinase</n> .
15972722187>16 women were treated with methadone to prevent withdrawal symptoms .
97890258093><n>Galphaq</n> , <n>Galpha12</n> , and <n>Galpha13</n> , but not <n>Galphai</n> , activate <n>SRF</n> through <n>RhoA</n> .
27133109296>Fundus changes in ( type II ) mesangiocapillary glomerulonephritis simulating drusen : a histopathological report .
93233663574>The <n>malate synthase gene</n> , <n>MLS1</n> , of the yeast Saccharomyces cerevisiae is transcriptionally regulated by the carbon source in the growth medium .
102055883924>OBJECTIVE : To follow-up prospectively patients with arthritis after infection with beta-haemolytic streptococci of Lancefield group A ( beta HSA ) , with emphasis on clinical characteristics and serological features .
20766207056>Gemfibrozil in hyperlipidaemic patients with peripheral arterial disease : some undiscovered actions .
108400015382><n>Mucin gene</n> expression has been shown to be altered in many intestinal diseases and especially cancers of the gastrointestinal tract .
13992069679>The results support earlier reports that <n>collagenase</n> inhibitors are useful in controlling blister formation in recessive dystrophic epidermolysis bullosa .
38188664500>Framingham Type A behavior was positively associated with diastolic blood pressure ( r = 0 . 17 , p less than 0 . 05 ) among the women .
83161005085>The neglect of Richards's theory demonstrates the range of factors , other than the strictly scientific , which can be important in determining the influence or otherwise of a psychological theory .
89974904719><n>C / EBP beta V</n> > A selectively binds only the subset of <n>C / EBP sites</n> that are also <n>DBP sites</n> , both as oligonucleotides and within the natural contexts of the <n>albumin</n> and <n>cholesterol hydroxylase promoters</n> .
18897539675>The nucleotide ( nt ) sequences of the exons , exon / intron boundaries and 5'- and 3'-untranslated regions were determined .
105340485248>The first algorithm , FOREPROJ , is a fast-forward projection algorithm that allows calculation of the 3-D attenuation correction factors ( ACF's ) directly from a two-dimensional ( 2-D ) transmission scan , without first reconstructing the attenuation map and then performing a 3-D forward projection .
90043045057>The aim of this study was to assess the reproducibility of a number of simplified clearance methods using chromium-51 ethylenediamine tetraacetic acid ( 51Cr-EDTA ) and to compare these with the multiple blood sample technique .
114356053684>Site-directed mutagenesis of <n>CAR</n> revealed that <n>CAR residues Leu73 and Lys121 and / or Lys123</n> are critical contact residues , with Tyr80 and Tyr83 being peripherally involved in the binding interaction with the Ad5 , Ad9 , Ad12 , and Ad41L fiber knobs .
66980478297>The <n>Prolactin</n> levels were within the physiological norms ; the responses to <n>TRH</n> were normal , and elevated only in a few cases .
94215082037>To investigate the activity of <n>TCF11</n> through this selected site , both alone and in the presence of <n>MafG</n> , we have used a transient transfection assay .
93972612727><n>Interleukin-1</n> levels remained low throughout the course .
104136765063>This dominant-negative effect of <n>FRNK</n> was reversed by a point mutation ( Leu-1034 to Ser ) which prevented <n>FRNK</n> localization to focal contact sites .
17870858999>In ten other experiments ( 5 experimental and 5 control rats ) 99mTc-sulfur colloid was injected intravenously .
107237237828>Additionally , the mouse promoter contains 22 copies of a <n>CT dinucleotide repeat sequence</n> located approximately 155 bp 5' to exon 1 .
104136764986>Expression of various <n>FAK mutants</n> in the FAK- cells showed that <n>FAK kinase</n> activity , the <n>Tyr-397 / SH2 domain binding site</n> , and the first proline-rich <n>SH3 binding region</n> in the <n>FAK C-terminal domain</n> were individually needed to promote full FAK-mediated FAK- cell migration to <n>FN</n> whereas direct <n>paxillin</n> binding to <n>FAK</n> was not required .
76445032314>In contrast , over-expression of <n>RAR beta</n> only poorly restored differentiation , although it could replace <n>RAR gamma</n> for the activation of target genes .
8030704943>CONCLUSION : Human preterm birth is associated with significantly lower progesterone / 17 beta-estradiol ratios than those of women with preterm labor delivered at term .
18909893087>Thus , two very different regulatory elements are used to mediate estrogen induction of related genes in chickens and amphibians .
8139031565>Specifically , by oligonucleotide-directed site-specific mutagenesis , we demonstrate that of 10 cysteine residues in the ORF4 polypeptide , only C-421 and C-426 are essential for transactivator function and suggest that these cysteine residues may participate in critical protein-protein interactions rather than protein-nucleic acid interactions to mediate ORF4 inducibility .
2149566993>The ratio of P-31 NMR-S derived inorganic phosphates [ Pi ] to phosphocreatine [ PCr ] was significantly greater at rest in LVH baboons [ 0 . 53 + / - 0 . 06 versus controls = 0 . 41 + / - 0 . 17 ; P less than 0 . 05 ] .
77917687779>The effect of these cell cycle regulators is not specific to the <n>rap1s</n> or <n>hmr delta A mutation</n> , since <n>swi6</n> , <n>swi4</n> , and <n>clb5 mutations</n> also suppress mutations in <n>SIR1</n> , another gene implicated in the establishment of silencing .
97841923050>Some of the <n>peptide : MBP fusions</n> were also analyzed using surface plasmon resonance .
20496172659>3 .
115858569951>METHODS : We studied the clinical benefit of depth-dependent RR , nonuniform AC using a scanning line source , and scatter correction ( photon energy recovery [ PER ] ) compared with filtered backprojection alone .
22965096544>All 89 participating household members were anti-HIV seronegative , and 78 who were tested were <n>serum p24 antigen</n> negative .
77999312308>In contrast , a <n>Maf-related protein</n> , <n>Nrl</n> , completely mimicked <n>c-Maf</n> actions .
104775976831><n>TRAF2</n> is a potent activator of a <n>95-kDa serine / threonine kinase</n> termed <n>germinal center kinase related</n> ( <n>GCKR</n> , also referred to as <n>KHS1</n> ) , which signals activation of the <n>SAPK</n> pathway .
117235001560>Clinical and epidemiological characteristics of oral squamous cell carcinoma in women BACKGROUND : Squamous cell carcinoma ( SCC ) of the oral cavity occurs mainly in the male population .
21645858349>The <n>TraD protein ( 83 , 899 Da )</n> contains three hydrophobic regions , of which two are located near the amino-terminal region .
72963037159>Responses to brainstem of nuclei medialis dorsalis , lateralis posterior were of considerably longer latency .
95069903718>Human <n>ZFM1 protein</n> is a transcriptional repressor that interacts with the <n>transcription activation domain of stage-specific activator protein</n> .
7433357301>Reaction times to tachistoscopically presented stimuli in diabetics .
5407079266>Following the satisfactory results and taking into account that the complications had reduced to a very low rate ( in 2 cases lead tip displacement and pouch haematoma occurred respectively ) , the Authors consider the adopted method an useful approach for PMK implantation particularly when the use of the vena cephalica is deemed impossible .
95823508745>In patients with type IA maple syrup urine disease , the <n>E1alpha subunit</n> is affected , resulting in the loss of <n>E1</n> and <n>branched-chain ketoacid dehydrogenase</n> catalytic activities .
26498113326>Postcoital contraception : a family planning study .
82645919273>These data indicate that the largest subunit of <n>RNA polymerase II</n> and <n>TFIIB</n> are important determinants of transcription start site selection in S . cerevisiae and suggest that this function might be conferred by interaction between these two proteins .
10487953320>Two patients with recurrent tumors had high S-phase fractions both on the first resected specimens and at the time of the second operation .
82223848309>SIN-1 had no influence on either the ischemic parameters in the surface electrocardiogram ( ECG ) or the intracoronary ECG .
96536412318>Human isoforms , designated 1 to 4 , differ from each other by the start codon used .
35207294075>No relevant changes in heart rate , body weight , and plasma levels of <n>renin</n> activity and aldosterone concentration were observed .
8387994948>The <n>orf61 gene product</n> , when expressed from an exogenous promoter , inhibited int-mediated integration at the <n>chromosomal attB site</n> .
51281495385>Surgical treatment of pathologic scars of myocardial infarct .
85858833743>Hybrid female mice ( C57BL x CBA ) were paired with breeder males ( CD-1 ) and LNG pellets were implanted on day 0 , the day on which copulation plugs were found , or on day 2 or day 3 in the postcoital period .
16628844628>Temafloxacin 400 mg b . i . d . administered orally for 28 days represents a safe and effective treatment for chronic bacterial prostatitis .
18981642518>The currently proposed extended arch repair should be reserved for the small group of infants with transverse aortic arch to ascending aorta diameter ratios ( arch indices ) of less than 0 . 25 .
36736401504>Low <n>MAO</n> subjects showed a pattern of higher scores in KSP Impulsiveness , EPQ Neuroticism , and KSP Somatic Anxiety and Irritability and lower scores in KSP Socialization , in line with personality profiles found in alcoholics , psychopaths , and suicide attempters who also tend to have low platelet <n>MAO</n> activity .
10851745657>It brings about fatigue , negative moods , and impaired health , sleep , safety , and working capacity .
108804862765>Next , we show that two EMS-induced mutations , previously shown to interact genetically with <n>zipper ( Ebr )</n> , disrupt the <n>RhoA locus</n> .
112928447094><n>HSF</n> binds DNA as a trimer , and additional trimers can bind DNA co-operatively .
112091009882>Apart from antimicrobial properties , recent data indicate that PMN also exert anti-inflammatory effects by stimulation and release of cytokine antagonists such as <n>interleukin-1 receptor antagonist</n> ( <n>IL-1ra</n> ) .
11116084438><n>Mouse Impact</n> is a paternally expressed gene encoding an evolutionarily conserved protein of unknown function .
89948252410>BACKGROUND : Mitosis is regulated by <n>MPF</n> ( <n>maturation promoting factor</n> ) , the active form of <n>Cdc2 / 28-cyclin B complexes</n> .
88928595298>We report an example of an MDV-transformed T-lymphoblastoid cell line ( T9 ) expressing high levels of a <n>truncated C-MYB protein</n> as a result of RAV integration within one <n>c-myb allele</n> .
51325583722>The interaction of caffeine , theophylline and theobromine with <n>monoamine oxidase</n> inhibitors .
75490057422>However , parallax measurements showed that at 150K , collapse of Epon sections does not take place .
114040191177>To gain an understanding of the <n>mGSTM2</n> regulation , we have also cloned and analyzed its promoter region .
88164839987>Mutations in three loci ( <n>SIC1</n> , <n>SWI5</n> , and <n>RIC3</n> ) were identified .
79641625713>Therefore , mechanisms that control activation of the <n>MAP kinase cascade</n> temporally and spatially may be important for specification of cellular responses .
32374463929>None had a past history of opportunistic infections ; neither did any have lymphopenia .
86266674918>EMSA competition experiments showed that mutations within the direct repeats failed to compete for binding of the nuclear proteins to labeled wild type oligonucleotide .
79804402478>In H4IIE rat hepatoma cells , glucocorticoids , retinoic acid and cyclic AMP ( cAMP ) increase <n>PEPCK gene</n> transcription whereas <n>insulin</n> and phorbol esters have the opposite effect .
97304131118>Until such investigations are performed , we conclude that the role for adjuvant treatment is questionable and that TME surgery is preferred as the treatment option for Stage T1-T3 rectal cancers .
107373669758>It was established that intrathecal or intraperitoneal PTFL , elevated the nociceptive threshold for mechanical stimuli in the formalin test in rats .
83823033825>The <n>E1 nuclear transport motif</n> is highly conserved in the animal and human papillomaviruses and is encoded in a similar region in the related <n>E1 genes</n> .
111609298176>Rapid evolution of the DNA-binding site in <n>LAGLIDADG homing endonucleases</n> .
24558219074>The gene is contained within a <n>1 . 8-kilobase AccI-EcoRI restriction fragment</n> mapping at map coordinates 0 . 136 to 0 . 148 in the <n>UL region</n> of the EHV-1 genome and is transcribed from right to left .
78968468251>Alternatively processed isoforms of <n>cellular nucleic acid-binding protein</n> interact with a suppressor region of the <n>human beta-myosin heavy chain gene</n> .
75121595574>Improvement of the polypyrimidine tract also increased the splicing efficiency , but to a degree slightly less than that obtained with the branchpoint mutation .
88398322502>Thus , the predicted <n>CD30v protein</n> retains most of the cytoplasmic region , but lacks the extracellular and transmembrane domains .
98868438861>To evaluate whether the human gene is also a target of thyroid hormone we have searched for <n>T3-responsive elements</n> in <n>NRGN</n> cloned genomic fragments spanning the whole gene .
25477063197>Validity of immunohistology and in situ hybridization in the differential diagnosis of cytomegalovirus pneumonia and idiopathic interstitial pneumonia after allogenic bone marrow transplantation .
7575416175>This work , therefore , also emphasizes the importance of careful choice of oligonucleotide and cDNA probes to study <n>PKC zeta mRNA</n> .
92376953560>A prospective observational study was conducted to identify early indicators of acute dengue virus infection .
76473035411>The <n>homeobox gene ATK1</n> of Arabidopsis thaliana is expressed in the shoot apex of the seedling and in flowers and inflorescence stems of mature plants .
44879204989>From the Icelandic Red Cross activities .
982787860>Since <n>glutathione peroxidase</n> ( <n>GPX</n> ) and <n>superoxide dismutase</n> ( <n>SOD</n> ) play a significant role in erythrocyte antioxidative defence , it is very important to determine their activity in occupationally exposed workers .
27922701669>Oligosynaptic EPSP components were consistently modulated only in the superficial peroneal responses in flexor motoneurons , which exhibited enhanced amplitude during the flexion phase .
113570632916>Like the <n>consensus mammalian LHbeta gene</n> , the 5'-flanking region of the <n>gpLH / CGbeta gene</n> contains a single TATA sequence 37 bp upstream of the translation start codon .
40159884679>Marrow cell necrosis in anorexia nervosa and involuntary starvation .
67384106501>Blood pressure in children .
87683773207>Because the <n>hcf109 locus</n> was mapped at a distance < 0 . 1 centimorgans from the <n>phytochrome C gene</n> , its molecular characterization by positional cloning is possible .
94835969377>Despite this there was no difference in the intubating conditions at one minute with 25 excellent / 5 good in the suxamethonium group and 27 excellent / 3 good in the rocuronium group .
8030243698>However , by an <n>NS35-specific RNA</n> capture assay , the multimers were shown to possess the RNA-binding activity previously demonstrated for <n>NS35</n> .
111603079659>This molecule , <n>wH22xeGFP</n> , consists of the <n>entire humanized anti-FcgammaRI mAb H22</n>1 with <n>eGFP</n> genetically fused to the C-terminal end of each <n>CH3 domain</n> . <n>wH22xeGFP</n> binds within the ligand-binding region by its <n>Fc</n> end , as well as outside the ligand-binding region by its <n>Fab</n> ends , thereby cross-linking <n>FcgammaRI</n> .
97075773388>In contrast , the distribution of endocytic markers is not affected .
10545281658>For example , introduction of immunogenic and purification tag sequences into the C-terminal coding region significantly decreased <n>bop gene mRNA</n> and protein accumulation .
106523629130>Together , these data suggest that the carboxyl terminus of <n>CFTR</n> contains a tyrosine-based internalization signal that interacts with the endocytic adaptor complex <n>AP-2</n> to facilitate efficient entry of <n>CFTR</n> into clathrin-coated vesicles .
18249447196>After treatment with tunicamycin , the transfectants secreted unglycosylated 18-kDa polypeptides which could also bind <n>IgE</n> .
11048832571>Fisher's exact test or Pearson's chi2 test were used for statistical analysis .
81399286148><n>RNP1</n> , a new ribonucleoprotein gene of the yeast Saccharomyces cerevisiae .
86128523667>RESULTS : Basal <n>plasma IGF-I</n> levels as well as body mass index ( BMI ) were lower in amenorrheic patients than in healthy controls .
59595887595>Studies on Coxsackie B Type 5 virus infections .
20309101950>Polymerase chain reaction analysis of <n>ETS1 cDNA</n> identified several amplified products , indicating alternative splicing .
88165048007>Platelet-derived growth factor-dependent activation of <n>phosphatidylinositol 3-kinase</n> is regulated by receptor binding of <n>SH2-domain-containing proteins</n> which influence <n>Ras</n> activity .
115699004837>APC-resistance was determined with a functional method with high sensitivity and specificity for the <n>factor V</n> Leiden mutation .
84385846782>The activity of the <n>coat protein promoter</n> of chloris striate mosaic virus is enhanced by its own and <n>C1-C2 gene products</n> .
95473498006>The ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine ( ET-18-OCH3 ; edelfosine ) is a potent inducer of apoptosis in human tumor cells .
86730268642>The factor structure of "schizotypal' traits : a large replication study .
4792227307>Resistance to the simulated physiologic environment was tested by measured retention of mechanical properties after immersion times in pseudo-extracellular fluid ( PECF ) at 37 degrees C for as long as three years .
39312934587>In the absence of other stabilizers , increased sucrose can provide increased thermoresistance to the virus in 2 . 5% <n>albumin</n> .
16439432145>We found that lung cancer tissues of positive 67Ga scan expressed <n>TFR</n> , but those of a negative scan did not .
93716262925>The results of <n>replicase</n> assays performed with <n>mutant VP2</n> containing a deletion in its RNA-binding domain suggests that the essential role for <n>VP2</n> in replication is linked to the protein's ability to bind the mRNA template for minus-strand synthesis .
28022803500>No significant differences were found between the TS and the PTS .
98637209852>Recurrent arterial thrombotic disease on young onset and <n>protein S</n> deficiency .
75210099771>Three mutants ( <n>pms1</n> , <n>pms2</n> and <n>pms3</n> ) isolated earlier from MW104-1B were shown to correct in vitro constructed plasmids with defined DNA mismatches ( G / T , A / C , G / G , etc . ) poorly ( Kramer et al . , 1989a ) .
7597488832>Hemolytic jaundice due to <n>G6PD</n> deficiency causing kernicterus in a female newborn .
111321488289>The presence of locus-specific residues throughout the entire promoter region strongly suggests that the various <n>HLA class I loci</n> are differentially regulated .
94733174084>Copyright 1998 Academic Press .
38714454528>Computer assisted mapping in quantitative analysis of cerebral positron emission tomograms .
10619254442>Animal studies showed that beam equalization significantly improved fluoroscopic and angiographic image quality .
12335611867>Maternal lactation .
112764267312>In mouse , <n>Mmip1</n> ( <n>Mad member interacting protein 1</n> ) and <n>Smc3</n> share 99% sequence identity and are products of the same gene .
45369645016>Intracellular pH , H ion flux and H ion permeability coefficient in bullfrog toe muscle .
31712216136>The variability is most likely a result of alternative splicing of exons from the primary <n>elastin transcripts</n> .
79295607344>Identification of the plakoglobin-binding domain in <n>desmoglein</n> and its role in plaque assembly and intermediate filament anchorage .
115171906740>Analysis of the promoter sequence revealed the presence of a major transcriptional start site , a canonical TATA box and putative cis regulatory elements for pituitary specific expression as well as an <n>E-responsive element</n> .
30373347678>We previously showed that the <n>upstream promoter element</n> of the <n>yeast RP39A gene</n> consists of these identical sequence motifs .
76800358020>The roles of phorbol esters and cyclic AMP in mediating the <n>GnRH</n> response were also investigated .
92000299154>Clinical and haematological signs are not specific in this setting , and the diagnosis relies on histological features , mainly bone marrow examination .
80334908033>In conclusion , the disposition of venlafaxine and O-desmethylvenlafaxine is markedly altered in renal disease ; therefore dosage adjustment is warranted for patients with creatinine clearance values below 30 ml / min .
115224311842>The prevalence of tobacco dependence diagnosed according to the ICD-10 criteria was higher in alcohol-dependent individuals ( 58 . 1% ) than in nondrinkers or social drinkers ( 12 . 8% ) .
76238258209>The carboxyl-terminal transactivation domain of <n>heat shock factor 1</n> is negatively regulated and stress responsive .
103707783911>Three new <n>aromatase</n> inhibitors have recently completed phase III evaluation as treatment of metastatic breast cancer in post-menopausal women whose disease has progressed despite tamoxifen therapy : anastrozole ( ARIMIDEX , Zeneca ) , letrozole ( FEMARA , Novartis ) and vorozole ( RIVIZOR , Janssen ) .
93058708132>The recognition specificity of the <n>p55 PDZ</n>1 <n>domain</n>1 appears to be unique , since the three <n>PDZ domains</n> of <n>hDlg</n> ( human lymphocyte homologue of the <n>Drosophila discs large tumor suppressor</n> ) do not bind the cytoplasmic domain of <n>glycophorin C</n> .
114359831313>Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-up .
89721824727>The <n>Fas receptor</n> mediates a signalling cascade resulting in programmed cell death ( apoptosis ) within hours of receptor cross-linking .
88689547198>Moreover , it also discusses the effects of antihypertensive drugs currently regarded as first-choice agents , i . e . calcium antagonists and the <n>angiotensin converting enzyme</n> inhibitors , on intrarenal hemodynamics .
114327484814>Regulation of <n>laminin beta2 chain gene</n> expression in human cancer cell lines .
79565789166>Lesion diameters of greater than 20 mm and the large sessile-type configurations were factors that were associated with incomplete removal .
4732497220>Effect of intraventricular administration of <n>streptolysin O</n> on the electroencephalogram of rabbits .
110461466632>Thus , diamide treatment of nuclear extracts strongly reduces the binding of <n>NFI proteins</n> , and the addition of higher concentrations of dithiothreitol to nuclear extracts from TG-treated cells restores <n>NFI-DNA</n> binding to levels in extracts from untreated cells .
21326364162>Subjects were 16 male chronic schizophrenics consisting of 8 DST suppressors and 8 nonsuppressors .
28397163297>In these cells , <n>E2 proteins</n> had little or no stimulatory effect on the transcriptional activity of the <n>HPV-11 enhancer-SV40 promoter</n> .
7864652264>Constructs designed and expressed were <n>E2L1 ( 1-98 )</n> , <n>E2L1 . H1 ( 1-128 )</n> , <n>E2L2 ( 120-233 )</n> , <n>E2H1 . L2 ( 98-233 )</n> , and <n>E2L1 . H1 . L2 ( 1-233 )</n> , where numbers in parentheses give the amino acid sequence for the portions of the <n>E2</n> component incorporated into a construct .
97864049764>633+ / -258 aggregates / ml at 0 rpm ; P < 0 . 001 ) .
78327796749>Deglycosylation with <n>endoglycosidase H</n> showed that the mutant receptors had mainly high-mannose oligosaccharide chains .
46329675060>Pulmonary arterial pressure and structure in the patas monkey after prolonged administration of aminorex fumarate .
4298934912>This multiple-electrode array for round window cochlear implantation is a robust , reliable system for inserting 20 mm along the scala tympani with a minimum of trauma and can provide for bipolar stimulation .
10932679749>Although there is little evidence that diet composition plays a clinically important role in the absorption or expenditure of energy , it does appear to play a role in food intake .
890613917>This observation calls for careful monitoring of calcium and <n>alkaline phosphatase</n> values and possible adjustments of vitamin D intake when fortifiers are used for extended periods .
38917663909>Interference with <n>rheumatoid factor</n> was only observed in the ELISA enzygnost if sera were not pretreated with latex adsorbents .
84966018281>A comparison of the promoters for <n>muMIP-1 beta</n> and <n>muMIP-1 alpha</n> reveals a conserved <n>CK-1 element</n> , but transient expression studies in RAW 264 . 7 macrophages with proximal fragments of either the <n>muMIP-1 beta</n> or the <n>muMIP-1 alpha 5' promoter</n> fused to a <n>human growth hormone reporter gene</n> link LPS-inducibility in both to promoter segments near to , but not identical with , the <n>consensus CK-1 sequence</n> .
114864761133>Cardiac markers <n>troponin T</n> , <n>CK-MB</n> mass and <n>myoglobin</n> were helpful in the differential diagnosis of chest pain , even when the ECG was unremarkable or nonspecific .
16575947720>We have determined that the mutants define two complementation groups , designated <n>cgs1+</n> and <n>cgs2+</n> ( continues to grow in stationary ) .
76786958658>The ectopic expression of <n>Oct-3 / 4</n> in hybrid cells under a constitutive promoter is sufficient for transcriptional activation of an octamer-dependent promoter .
89384208573>The accumulation of both <n>LHA4</n> and <n>LHA2 mRNAs</n> is induced by the addition of exogenous sugars and this induction appears to be dependent on sugar uptake and metabolism , because mannitol and 3-O-methylglucose do not stimulate mRNA accumulation .
71906276157>A further study on <n>plasminogen activator</n> release by vasoactive agents in the isolated perfused dog leg .
79699547959>Distal lower motor neuron syndrome with high-titer <n>serum IgM anti-GM1 antibodies</n> : improvement following immunotherapy with monthly plasma exchange and intravenous cyclophosphamide .
104339709806><n>Spfkh1</n> is transcribed in one open reading frame that contains the DNA binding domain , nuclear localization signal and transactivation domain .
21482913403>Using appropriate <n>synthetic HSE oligonucleotides</n> , three types of clones with potential <n>HSE binding domains</n> were isolated from a tomato lambda gt11 expression library by DNA-ligand screening .
108607522378>The presence of such a putative RNA- binding domain suggests a mechanism for the observed autoregulation of bacteriophage <n>T4 DNA polymerase</n> synthesis by binding to its own mRNA .
93805073984><n>Glutathione S-transferase</n> ( <n>GST</n> ) <n>-E2F</n> and <n>GST-DP fusion proteins</n> were found to cooperate in binding to the three <n>E2F sites</n> in the <n>DNA polymerase alpha gene promoter</n> in vitro .
21195302721>Influence of metoprolol treatment on sympatho-adrenal activation of fibrinolysis .
83832142925>Secondary cleavage of <n>RT</n> at <n>Trp-595-Tyr-596 of Pol</n> yields a truncated form lacking the <n>C-terminal RNase H domain</n> .
8990168265>Although <n>p48 gene</n> induction is dependent on <n>STAT1</n> and <n>JAK1</n> , activated <n>STAT1</n> does not bind to <n>GATE</n> .
14316028399>The second method , the "macro" assay , has a sensitivity range of 0 . 03-5 . 0 micrograms phosphorus with 100-500 microliters HClO4 .
108610867856>In contrast , <n>c-Src-derived construct</n> ( <n>a-Src</n> ) , that was excluded from detergent-resistant membranes , could not restore the series of phagocytosis signaling .
95604305544><n>Ime1</n> plays a pivotal role in the initiation of meiosis in a / alpha diploid cells of Saccharomyces cerevisiae .
119027812285>Concentrations of N ( O3- ) -N and N ( H3- ) -N at Deoprayag varied from 0 . 30 to 0 . 50 and 0 . 02 to 0 . 12 mg / L , respectively , depending on season .
109381027661>To characterize this effect , we looked for targets of <n>NS1 influenza virus protein</n> among cellular translation factors .
1985102596>Innervation of the ventral diaphragm of the locust ( Locusta migratoria ) .
64123856985>In the 37 patients without lung disease respiratory muscle weakness was accompanied by significant decreases in vital capacity , total lung capacity , and maximum voluntary ventilation ; by significant increases in residual volume and arterial carbon dioxide tension ( PaCO2 ) ; and greater likelihood of dependence on ventilators , atelectasis , and pneumonia .
568375643>Of 600 mediastinoscopies carried out from 1966 to 1973 , 479 were performed to assess the operability of a pulmonary carcinoma .
10077533485>These data provide the molecular tools for the final identification of the <n>MKS</n> and the <n>MUL genes</n> .
106247879636>Compared to those with normal renal functions , these patients were older ( P < or = 0 . 01 ) , had significantly elevated blood pressures ( P < 0 . 01 or P = 0 . 0001 ) , and in the case of Type 1 DM , with a higher body mass index ( P = 0 . 0001 ) and waist-hip ratio ( P < 0 . 01 ) .
112027051040>Implications in biomonitoring of the observed accumulation patterns , especially in the different tissues of Posidonia oceanica , are discussed .
13300779794><n>T-cell receptor beta</n> ( <n>TCR beta</n> ) gene rearrangements occur in a third of early B-cell acute lymphoblastic leukemias ( ALLs ) .
77766852524>This study assesses the feasibility and toxicity of adoptive immunotherapy with tumor infiltrating lymphocytes and <n>recombinant interleukin-2</n> in 29 patients who underwent resection for stage III non-small-cell lung cancer .
105645935004>The <n>MXR gene</n> encodes a half-transporter and the absence of cytogenetic evidence of coamplification of other regions suggests that a partner may not be overexpressed , and instead the <n>MXR half-transporter</n> homodimerizes to mediate drug transport .
84321375536>We compared the parameters <n>pleural adenosine deaminase</n> ( <n>PADA</n> , determined in 405 patients ) , the <n>PADA / serum ADA</n> ratio ( <n>P / SADA</n> ; 276 cases ) , <n>pleural lysozyme</n> ( <n>PLYS</n> , 276 cases ) , the <n>PLYS / serum LYS</n> ratio ( <n>P / SLYS</n> ; 276 cases ) , and <n>pleural interferon gamma</n> ( <n>IFN</n> , 145 cases ) regarding their ability to differentiate tuberculous pleural effusions from others .
8289784936>176 : 787-792 , 1992 ; M .
25212171869>An immunologically related protein was detected in ribosome and membrane fractions of mitochondria from Saccharomyces cerevisiae .
84219101948>As the components of these complexes , at least five <n>TRBPs</n> ( <n>p30</n> , <n>p37</n> , <n>p46</n> , <n>p50</n> , and <n>p56</n> ) showing specific binding to the <n>TAR RNA</n> were detected in the uv cross-linking assay .
117433609246>Acute stress in 7 rats also increased the mean amount of <n>IL-6</n> released in the urine by 31 . 5% from 775 . 9 + / - 69 . 2 to 1 , 021 . 1 + / - 93 . 3 pg . / ml .
81643028136>All of the basal TPN solutions were isonitrogenous and identical in nutrient composition , except for the difference in energy level , which was adjusted with glucose .
114094259337>We used stored plasma samples from 409 patients in the National Institute of Neurological Diseases and Stroke ( NINDS ) <n>tissue plasminogen activator</n> ( <n>t-PA</n> ) Stroke Trial to examine the relationship between an <n>apolipoprotein ( Apo ) E2</n> or an <n>Apo E4</n> phenotype and a favorable outcome 3 months after stroke , the risk of intracerebral hemorrhage , and the response to intravenous <n>t-PA</n> therapy .
23034703362>The introns are 1 . 6-1 . 9 kbp long .
57403895689>Relations between adrenergic mechanisms and analgesic effects .
112832561815>Here we demonstrate that <n>native MRCK</n> exists in high-molecular-weight complexes .
112384475146>In vitro binding studies demonstrate that <n>eIF-5A</n> is required for efficient interaction of <n>Rev-NES</n> with <n>CRM1 / exportin1</n> and that <n>eIF-5A</n> interacts with the nucleoporins <n>CAN / nup214</n> , <n>nup153</n> , <n>nup98</n> , and <n>nup62</n> .
19487832573>The antihypertensive effect of Estulic has been examined over a 12-month period in 101 hypertensive patients .
24957453056>The thrombolytic effects of native <n>tissue-type plasminogen activator</n> ( <n>AK-124</n> ) on experimental canine coronary thrombosis .
85147571351>Both <n>immunophilins</n> may have important roles in receptor assembly and may represent a new category of ligand- and calcium-dependent modulators of protein function .
104906093359>Substitutions of region I with synthetic sequences showed that no specific sequence but rather repeats of three or more consecutive adenines or thymines , without interruption by guanine or cytosine , are required for the <n>ARS</n> activity .
30247038475>The coding region of 2385 nucleotides corresponds to a polypeptide chain of 795 amino acids , giving a molecular weight of 91 , 555 for the <n>hsp108 protein</n> .
62818916076>Both neural and hormonal pathways and both opiate and nonopiate substances play roles in the complex modulation of pain transmission .
102314857844>Sequence analysis suggests that <n>TtrA</n> contains a molybdopterin guanine dinucleotide cofactor and a [ 4Fe-4S ] cluster , that <n>TtrB</n> binds four [ 4Fe-4S ] clusters , and that <n>TtrC</n> is an integral membrane protein containing a quinol oxidation site .
104877444260>A tyrosine-based sorting signal in the <n>beta2 integrin cytoplasmic domain</n> mediates its recycling to the plasma membrane and is required for ligand-supported migration .
18953849786>The <n>IE0 gene</n> product also transactivated the <n>IE1 promoter</n> but did not affect expression from its own promoter .
45469745026>Variations of the timing of deflections in the His bundle recordings .
115628701439>The probability of treatment with lamotrigine being maintained for six months was 86% , for twelve months 61% and for three years 31% .
4974945283>The ventilation did not increase when PACO2 was increased .
85348556960>The <n>Arabidopsis FAD7 gene</n> encodes a <n>chloroplast omega-3 fatty acid desaturase</n> that catalyzes the desaturation of lipid-linked dienoic fatty acids ( 18 : 2 and 16 : 2 ) .
91548198620>Transient overexpression of <n>c-Jun</n> induced <n>tenascin-C</n> expression in primary REF and in FR3T3 , an established fibroblast cell line .
99170641085>Dual roles of <n>p82</n> , the clam <n>CPEB homolog</n> , in cytoplasmic polyadenylation and translational masking .
18699685626>Arterial radioactivity content after the intravenous administration of HMPAO in seven human subjects was analyzed .
12415889465>The alterations of 5-HT and 5-HIAA levels in several regions of the brain under the conditions examined may indicate that IDPN's neurotoxicity primarily affects 5-HT-containing neurones .
104643024471>The recruitment of constitutively phosphorylated <n>p185 ( neu )</n> and the activated mitogenic pathway proteins to this membrane-microfilament interaction site provides a physical model for integrating the assembly of the mitogenic pathway with the transmission of <n>growth factor</n> signal to the cytoskeleton .
75517877432>The outcome of the optimization of the seven-field plan prompted an investigation into the best results that could be achieved by an "ideal" conformal radiotherapy technique .
79491644434>The site-directed mutation of the <n>kappa B motif</n> in <n>IL-6 / CAT</n> plasmid resulted in the complete abrogation of <n>IL-6 promoter</n> activity in these cells .
117739217298>METHODS : <n>P-selectin</n> expression of nonstimulated and ADP-stimulated platelets was flow cytometrically measured before the clopidogrel loading dose and on 3 consecutive days in 52 patients with coronary artery disease : 21 patients in group 1 received 300 mg of clopidogrel after stent implantation and 11 patients in group 2 received the higher 450-mg clopidogrel loading dose followed by a daily dose of 75 mg of clopidogrel for both groups .
75927713137>The <n>mouse beta 2-syntrophin gene</n> ( > 33 kilobases ) contains seven exons , all of which have homologues at the corresponding position in the <n>alpha 1-syntrophin gene</n> .
94020296986>Interestingly , the avirulent strain H37Ra showed weak hybridization with these two probes , suggesting that these genes might have been deleted in the avirulent strain or are present in limited copy numbers as opposed to those in the virulent strain H37Rv .
114393433780>In contrast to <n>MPc3</n> , data indicate that the <n>Pc protein M33</n>1 does not interact with <n>AF9</n> .
85094198911>Expression of this protein in E . coli demonstrated that tyrosine was incorporated during suppression and that <n>yeast cytoplasmic TyrRS</n> activity was produced .
19931813451>Nucleotide sequence analysis of the <n>Pseudomonas putida PpG7 salicylate hydroxylase gene</n> ( <n>nahG</n> ) and its 3'-flanking region .
104987062383>Taken together , our data suggest that <n>PecS</n> attenuates <n>pelD</n> and <n>pelE</n> expression rather than acting as a true repressor like <n>KdgR</n> .
109729804124>In several cell lines , <n>mTOR</n> or its downstream targets can be regulated by <n>phosphatidylinositol ( PI ) 3-kinase</n> ; <n>protein kinases A , B , and C</n> ; <n>heterotrimeric G-proteins</n> ; a PD98059-sensitive <n>kinase</n> or calcium ; as well as by amino acids .
90890935083>Sequences downstream of the two <n>human CA genes</n> , possibly containing homologous enhancer elements , have not yet been reported .
89786901258>This establishes <n>Rad3 / Mec1</n> as the only conserved protein which is required for all the DNA structure checkpoints in both yeast model systems .
112262281436>However , plasmids carrying the <n>yeast TyrRS gene</n> could not be stably maintained in E . coli .
105280355316>16 percent , P < 0 . 001 ) , and sustained normalization of <n>serum alanine aminotransferase</n> levels ( 41 percent vs .
19562859692>The sequence was determined of 6493 nucleotides encompassing the <n>bet genes of Escherichia coli</n> which encode the osmoregulatory <n>choline-glycine betaine pathway</n> .
92741131589>135 students had a count of less than 50 eggs / 10 ml . urine and 56 had more than 50 eggs / 10 ml .
113400853664>Based on the hypothesis that evolutionarily conserved regions are functionally important and likely to interact with coactivators , we compared the amino acid sequence of <n>C / EBPalpha</n> from different species ( frog to human ) and identified four highly conserved regions ( <n>CR1-CR4</n> ) within the transactivation domain .
97183728859>Evidence for a novel MAPKKK-independent pathway controlling the stress activated <n>Sty1 / Spc1 MAP kinase</n> in fission yeast .
104136623192>A recombinant derivative harboring the pMJ101 replication region proved to be compatible with pJM1 , a plasmid containing the iron acquisition system required for the virulence of V . anguillarum 775 , another important pathogen that causes vibriosis .
91864309133>Five of these have ocular or oculocutaneous albinism .
99997429998>NH3 and NO interaction with Si ( 100 ) - ( 2 x 1 ) surfaces .
46619615085>Normal values for the peripheral blood and bone marrow of the grey ( Armenian ) hamster .
19180106116><n>Lipoprotein lipase</n> ( <n>LPL</n> ) , a key enzyme in normal lipoprotein metabolism , has a complex pattern of regulation and tissue-specific expression .
75696401165>Protein electrophoresis showed decreased <n>albumin</n> levels in both groups , with lower values in G2 .
91686238130>A <n>xylE transcriptional fusion</n> to the putative <n>mxbD promoter</n> showed low-level expression in wild-type cells grown on one-carbon ( C1 ) compounds and no detectable expression in cells grown on succinate .
110063314163>The variable phenotype of the allotetraploids could not be explained by cytological abnormalities .
1398074455>The <n>RNase MRP RNA gene</n> was deleted by insertional replacement and found to be essential for cellular viability , indicating a critical nuclear role for <n>RNase MRP</n> .
57190315667>Studies on the method of size reduction of medicinal compounds .
103905387480>A <n>human Raf-responsive zinc-finger protein</n> that binds to divergent sequences .
104414498165>Copyright 1999 Academic Press .
95142605943>One of these <n>small inteins</n> might be inactive or a <n>"pseudo intein . "</n> The results suggest a modular architecture for <n>inteins</n> , clarify their origin and relationship to other protein families , and extend recent experimental findings on the functional roles of <n>intein N , C , and EN motifs</n> .
88989163117>220 , 263-273 ) .
81947536119>As in S . cerevisiae , the sequence of <n>rhp51+</n> showed two <n>MluI cell-cycle boxes</n> and a putative DNA damage-responsive element in its upstream region .
103952831458>There was no competition between <n>activin A</n> and <n>OP-1</n> for availability of <n>Smad4</n> , indicating that the concentration of this common signal transducer is not limiting for generating the observed biological responses .
71400606950>Intra-articular dislocation of the patella .
83050589614>Pneumothorax during laparoscopic dissection of the diaphragmatic hiatus .
96564145277>Dosage in both cases was 0 . 2 g / m2 .
97269797268>Molecular cloning and functional characterization of <n>murine sphingosine kinase</n> .
98910497794>Processing of the polycistronic precursor requires <n>nucleases</n> also involved in <n>rRNA</n> processing , i . e . , <n>Rnt1p</n> and <n>Rat1p</n> .
110290451421>Hyperactivation of <n>Cdc2</n> in fission yeast causes cells to undergo a lethal premature mitosis called mitotic catastrophe .
79354151577>Tissue-specific expression of the <n>diazepam-binding inhibitor</n> in Drosophila melanogaster : cloning , structure , and localization of the gene .
15519108095>Competition analysis by gel mobility shift electrophoresis indicates that this DNA-protein interaction is novel and not related to many transcription factors previously reported .
103472208790>Nevertheless , we demonstrate that the entire three-component yeast capping apparatus , consisting of <n>RNA 5'-triphosphatase</n> ( <n>Cet1p</n> ) , <n>RNA guanylyltransferase</n> ( <n>Ceg1p</n> ) , and <n>Abd1p</n> could be replaced in vivo by the two-component mammalian apparatus consisting of a bifunctional <n>triphosphatase-guanylyltransferase Mce1p</n> and the <n>methyltransferase Hcm1 ( 121-476 ) p</n> .
20261475369>We purified a <n>Ca2+ / calmodulin ( CaM ) -dependent protein kinase ( CaM kinase ) from the yeast Saccharomyces cerevisiae</n> with properties similar to <n>mammalian type II CaM kinases</n> .
82515067063>The 247-kDa complex appears to contain two distinct protein-DNA complexes of approximately 232 and 256 kDa and represents two proteins covalently cross-linked to a single <n>DRE</n> oligonucleotide , while the 97 , 105 , and 115-kDa complexes represent single <n>protein-DRE</n> cross-links .
90323041248>Identification of a promoter-specific transactivation domain in the <n>herpes simplex virus regulatory protein ICP4</n> .
97030211094>In insects , <n>arylalkylamine N-acetyltransferases</n> ( <n>AANATs</n> ) have been implicated in several physiological processes , including sclerotization , inactivation of certain neurotransmitters , and , similar to the function in vertebrates , catalysis of the rate-limiting step in melatonin biosynthesis .
117106856506>Eliminating any subset of ASCUS reduces the ASCUS / SIL ratio but also significantly diminishes the sensitivity of the Papanicolaou test .
5178906>The enteric route is the principal mode of transmission for hepatitis A , but maximal levels of hepatitis A virus excretion occur before the onset of jaundice .
103232253728>Km values for ammonium , 2-oxoglutarate , NADH , glutamate and NAD+ were 6 . 5 , 3 . 5 , 0 . 06 , 37 . 1 and 0 . 046 mM , respectively .
13212777730><n>ROS</n> x <n>SRC</n> ( <n>R</n> ) contains a 16-amino-acid deletion that includes the 3' half of the transmembrane domain of <n>ros</n> .
15794724935>Unlike the typical enhancer element , this region functions in an orientation-dependent manner .
87787005092>We present this case because of the rarity of left ventricular involvement associated with ARVD .
92686521791>We describe a novel <n>zinc finger protein</n> , <n>dsRBP-ZFa</n> , isolated by screening an expression library with dsRNA .
25974843247>With respect to effective diffusivity of platelets ( De ) and the surface reactivity constant ( K ) , less significant differences were found among artificial materials .
64821798962>Catch-up growth was observed only for a 12-month period in 4 children with a bone age of 7 to 8 years .
86266127267>Am .
29600123667>The frequency of PPNG strains increased from 1 . 7% in 1981 to 6 . 7% in 1985 .
75923378623>These results suggested that <n>NfxB</n> negatively autoregulates the expression of <n>nfxB</n> itself .
91055301144>An egg protein , <n>lysozyme</n> , is a still unlabeled additive currently used in cheese preparation .
40707256553>Component P100 was associated with a frontal negativity of similar latency favoring the hypothesis of a dipolar occipital generator .
97421298124>W .
62094039986>No direct repeats flank the pseudogene in the <n>U2 / 4 locus</n> .
99746429965>Crossover in the specific heat of dilute magnets induced by critical spin-wave dynamics .
23575377083>The effects on reflex latencies but not on paCO2 or pHa were blocked by naloxone ( 2 mg / kg ) , and were not present in morphine-tolerant animals .
40589854997>Pharmacologic doses of vitamin B6 administered to lactating women have been reported to suppress <n>plasma prolactin</n> .
72825527138>In Group V , the salvaged tissue was primarily subepicardial with virtually no lateral zone of salvaged tissue ( ratio of salvaged subepicardium to salvaged subendocardium 14 . 8 + / - 1 . 9 to 1 ) .
34885324180>In a previous interim report we noted more prompt resolution of dermatomal signs and symptoms with acyclovir treatment .
90723613419>In cellular supernatant fraction , SHRSP showed a decrease of magnesium in many tissues and an elevation of the calcium to magnesium ratio when compared to age-matched WKY and SHRSR .
93378611416>Cloning of a <n>human phosphoinositide 3-kinase</n> with a <n>C2 domain</n> that displays reduced sensitivity to the inhibitor wortmannin .
8425228380>Selective bronchial intubation in the management of unilateral pulmonary interstitial emphysema .
27145253402>Kidney weight and kidney-to-body weight ratio were significantly elevated at the highest dose level after 10 weeks and at the two higher dose levels after 15 weeks of exposure .
95287661673>However , inhibition of both the <n>ERK / RSK</n> and the <n>p38 / MAPKAP kinase 2</n> pathways completely abolished NGF-induced <n>CREB</n> Ser-133 phosphorylation .
74757337363>Malaria , anaemia , and HIV-1 transmission in central Africa .
11727348099>Association with <n>HL-A W-27</n> .
108828507837><n>Endonuclease III</n> ( <n>Nth</n> ) of Escherichia coli is a <n>DNA glycosylase</n> essential for the removal of oxidised pyrimidine base residues from DNA .
97336474398>This sequence , <n>Thr-Gly-X-X-Gly-Asp-Gly-Lys-Ile-Phe</n> , forms part of the <n>B-loop</n> and is conserved in a wide variety of organisms that include bacteria , algae and archeabacteria .
108252004970>Hierarchy of <n>protein tyrosine kinases</n> in <n>interleukin-2</n> ( <n>IL-2</n> ) signaling : activation of <n>syk</n> depends on <n>Jak3</n> ; however , neither <n>Syk</n> nor <n>Lck</n> is required for IL-2-mediated <n>STAT</n> activation .
2176822801><n>Multifunctional protein kinase</n> ( <n>MFPK</n> ) phosphorylates <n>ATP-citrate lyase</n> on <n>peptide B</n> on two sites , BT and BS , on threonine and serine , respectively , <n>inhibitor 2</n> on a threonyl residue , and <n>glycogen synthase</n> at sites 2 and 3 .
113315969678><n>Prrp</n> can also associate with the <n>EVH1 domain</n> of <n>Mena</n> , another microfilament-associated protein .
93580459485>The full length cDNA sequence of a <n>Type I transforming growth factor-beta ( TGF-beta ) receptor</n> has been isolated from the filarial parasitic nematode Brugia pahangi .
7968409944>The sample includes all the HIV-infected-patients continuously referred to the Outpatient Service of the Infectious Diseases dept . of Bologna's "Ospedale Maggiore" General Hospital during some five days ( 19-23rd , July 1993 ) .
39648552457>Angiography was performed following the rCBF study and the degree of vasospasm was measured on the angiograms .
16180273891>Furthermore , no transcripts of the same size and having the same developmental profile as those generated by the <n>wild-type E10 fragment</n> were identified by probes covering the remainder of the cloned region .
84619818437>We discuss the need to use animals older than 3 months for the study of 'adult' regeneration phenomena since 3-month-old rats may be somewhat immature .
88087568937>Sequence analysis of reverse transcribed , amplified cDNA generated from total RNA isolated from transfected cells demonstrated the presence of abnormally spliced products containing 13 and 78 additional bases as well as the accumulation of unspliced mRNA .
83567928871>Furthermore , a <n>p21X protein</n> lacking the N-terminus of <n>Rex1</n> was expressed at high levels ; our data indicate that <n>p21X</n> is translated from the 1 . 6-kb mRNA which is derived primarily from deleted proviruses .
32938443979>Diet and atopic eczema .
25926401590>High values of both retinol and beta-carotene were found in full fat cheeses and whipping cream : from 179 . 0 ( cheese , Edam-type ) to 318 . 7 micrograms / 100 g ( whipping cream ) and from 86 . 7 ( cheese , Edam-type ) to 186 . 5 micrograms / 100 g ( whipping cream ) for all-trans retinol and total beta-carotene , respectively .
101327306458>Troubled CareNetwork gets pact from largest teacher union in Wis .
110043694123>OBJECTIVE : To evaluate the relationship between blood flow in the tumor assessed by color Doppler ultrasound , microvessel density , and <n>vascular endothelial growth factor</n> levels in endometrial carcinoma .
104308837768>Among mucus-secreting cells , the gastric gland mucous cells , Brunner's glands , accessory glands of pancreaticobiliary tract , and pancreatic ducts exhibiting gastric metaplasia are unique in that they express <n>class III mucin</n> identified by paradoxical <n>Con A</n> staining composed of periodate oxidation , sodium borohydride reduction , <n>Con A</n> , and <n>horseradish peroxidase</n> reaction .
28539223543>Elevated IOP developed in 35 patients ( 44 eyes ) during the study .
101963167157>To determine the function of <n>VZV gK</n> in virus growth , a series of <n>gK deletion mutants</n> were constructed with VZV cosmid DNA derived from the Oka strain .
97380877589>The effect of independent predictors on survival was examined in a Cox regression model with adjustment for existing illnesses .
1990122603>Ectopic <n>ACTH</n> syndrome and medullary thyroid carcinoma .
75178691914>We observed that dephosphorylation severely inhibits the DNA-binding ability of <n>C / EBP-delta</n> and its transactivating potential increases in the presence of cellular <n>phosphatase</n> inhibitors , such as okadaic acid and sodium orthovanadate .
97367157970>Furthermore , phosphatidylinositol ( 3 , 4 , 5 ) trisphosphate specifically stimulates the activity of <n>ILK</n> in vitro , and in addition , membrane targetted constitutively active <n>Pi ( 3 ) K</n> activates <n>ILK</n> in vivo .
36975874364>49 , XXXXY chromosome anomaly : an unusual variant of Klinefelter's syndrome .
79914372139>Propafenone is well tolerated in the majority of young patients .
9315632906>Furthermore , our novel observation that expression of a highly activated <n>FGFR3 kinase domain</n> is able to morphologically transform fibroblasts suggests that dysregulation of <n>FGFR3</n> has the potential to play a role in human neoplasia .
117969771662>Postdocs face hardship across mainland Europe .
79590112495><n>C / EBP alpha</n> also activates the promoter of the <n>rat class-I ADH gene</n> in a sequence-specific manner [ Potter et al . , Arch .
65885016347>An experimental long-term study .
75574249723><n>XYL1</n> was isolated as a highly expressed fusion clone from a <n>'lacZ</n> translational fusion library .
109034408364>Only transcripts specific for <n>TSGF-2</n> are detected in ovary and testes tissues of adults as well as in puparia , while neither gene is expressed during the larval developmental stages .
1130610113>Using RACE techniques we have cloned and sequenced one of the hamster liver <n>3-hydroxy-hexobarbital dehydrogenases</n> which catalyze not only cyclic alcohols but also 17beta-hydroxy-steroids and 3alpha-hydroxysteroids .
112336435201>Currently , the clinical use of 5-aminolaevulinic acid ( ALA ) induced <n>protoporphyrin IX</n> ( <n>PPIX</n> ) for photodynamic therapy ( PDT ) is limited by the maximum tolerated oral ALA dose ( 60 mg / kg ) .
79030998298>The presence of an unusual transcript possessing <n>IVS2C beta 1</n> at the 5' terminus suggests that cleavage of its splice acceptor is inefficient or negatively regulated .
96910376803>We found sequences related to this insertion in wild-type strains of N . crassa and other Neurospora species .
91518285957>The altered amino acid residues of the seven <n>mutant 9ORF1 polypeptides</n> clustered within three separate regions referred to as region I ( residues 34 to 41 ) , region II ( residues 89 to 91 ) , and C-terminal region III ( residues 122 to 125 ) .
114959208548>A one base pair mismatch within the corresponding region of the <n>CYP3A4 gene</n> was sufficient for a differential enhancer activity .
103471448790>The recombinant purified protein expressed in the baculovirus system had an approximate molecular size 20 kDa with <n>amino-terminal sequence of AVQGP</n> .
97362394461>During the 2h resuscitation period , extracellular aspartate and glutamate concentrations in the cerebral striatum were higher during hypoxaemic resuscitation ( p = 0 . 044 and p = 0 . 055 , respectively ) than during resuscitation with 21% O2 or 100% O2 , suggesting an unfavourable accumulation of potent excitotoxins during hypoxaemic resuscitation .
86423131350>When overexpressed in an appropriate cell line , <n>TAN-1C</n> prevented kappa B-dependent transactivation in transient reporter gene assays in a fashion similar to the structurally related protein , <n>Bcl-3</n> .
106815204732><n>Ras-GRF1</n> transiently expressed with <n>v-Src</n> was tyrosine-phosphorylated and showed significant <n>GEF</n> activity toward <n>Rac</n> , but not <n>Rho</n> and <n>Cdc42</n> , which was comparable with that induced by <n>Gbetagamma</n> .
87473438735>Protein films are distinctly different in mechanical profiles from those films made of other materials .
96019403276>The 5' flanking region of the <n>CD1 gene</n> contained the binding motifs for two cytokine-inducible transcription factors , <n>NF-IL2-A</n> and <n>NF-IL6</n> .
22487322885>This , together with the data obtained with haloperidol , suggests that a minimal increase in the firing rate of LC cells ( +140% ) is required before it could influence the turnover of NA , as measured by DOPAC changes .
63300826777>A .
82192279292>Replacement of the <n>CRE</n> with a second copy of the <n>AP-1 site</n> results in a level of transcriptional activity comparable with that of the wild-type sequence , but replacement of the <n>AP-1 site</n> with a <n>CRE</n> abolishes activity .
89882578718>Silencing can be restored by creation of a telomere at 13 kb from the reporter construct , or by insertion of 340 bp of yeast telomeric repeat sequence at this site without chromosomal truncation .
115003778606>In mammals , the transcriptional repressors in the <n>Wnt pathway</n> are not well defined .
84064192004>They were found to be seropositive for antibodies to hepatitis C virus by second-generation testing ( RIBA 2 , Ortho Diagnostic Systems Inc , Westwood , MA ) .
15055167069>Replacing the aspartic acid with a lysine but not with an alanine or valine residue allowed formation of disulfide-linked dimers .
111980531496>Acute effects of LI 160 ( extract of Hypericum perforatum , St John's wort ) and two of its constituents on neuroendocrine responses in the rat .
105674302791>Additional studies revealed that <n>bovine brain Galpha ( q / 11 )</n> could also bind to an N-terminal construct of <n>GRK2</n> , while no binding of <n>Galpha ( q / 11 )</n> , <n>Galpha ( s )</n> , <n>Galpha ( i )</n> , or <n>Galpha ( 12 / 13 )</n> to comparable constructs of <n>GRK5</n> or <n>GRK6</n> was observed .
22096057032>Within this sequence the <n>MSAS gene</n> was identified as a 5322-bp-long open reading frame coding for a protein of 1774 amino acids and 190 , 731 Da molecular mass .
17652695482>These introns belong to the class of nuclear pre-mRNA introns and contain typical 5'- and 3'-consensus sequences , as well as unique features .
35756562619>Due to its relatively soluble chemical form , 90Sr was rapidly translocated from lung to bone where a substantial portion was retained for a long period of time .
94327529385>Patients and their relatives must be informed about the available effective treatment possibilities and about the right moment for their application in an individual patient .
96527421889>Initially , we observed that unmutated <n>p53</n> is strongly expressed in premalignant mammary glands and in mammary tumors derived from the MMTV-c-myc strain .
1811243958>Regional cerebral blood flow ( rCBF ) measurements and psychiatric ratings were performed on seven schizophrenic patients ( mean age = 41 . 4 years ) who had been examined 18 years previously in a study that used similar psychiatric ratings and a comparable rCBF technique .
86681249804>The <n>Dox-A2 ORF</n> driven by the <n>TDH3 promoter</n> complemented the phenotype of a strain deleted for <n>sun2</n> .
18098542416>Examples are using more subjects or an improved research design , developing consensus statements or using meta-analysis .
81945498171>Eight highly trained male kayakers were studied to determine the relationship between critical power ( CP ) and the onset of blood lactate accumulation ( OBLA ) .
81591742737>The presence of the foreign gene was confirmed by Southern analysis .
108733866977>We have isolated and functionally characterized the mouse gene for the <n>C2 subunit</n> of the <n>20S proteasome</n> .
72688287120>A fluoroimmunoassay for the determination of serum of plasma levels of propranolol was developed using antibodies to propranolol coupled to magnetizable solid-phase particles and fluorescein-labeled propranolol as tracer .
109625646844>A <n>beta2 RARE reporter construct</n> in which the methylation-susceptible cytosines in the sense strand were replaced by thymine displayed marked loss of activity in a replicated chromatin-dependent manner .
43773284949>I .
72985233341>Effect of indomethacin and prostaglandin F2 alpha on parturition in swine .
37096277313>The subjects received a single 500 mg dose of acetaminophen i . v . and concentrations in plasma were measured for 360 minutes and in urine for 24 h in order to estimate the production of metabolites .
1007873478>The H-reflex recovery curve was obtained after stimulation of the median nerve at the elbow and recording from the flexor carpi radialis .
117918531657>The experimental results showed that the coagulation-electrooxidation process could efficiently remove the color and the COD from the simulated dye wastewater .
28330129291>The predicted <n>L mRNA</n> was 6398 nucleotides long and contained a single open reading frame corresponding to an <n>L protein encompassing 2109 amino acids</n> with a MW of 241 , 546 .
103504845587>The kinetics of <n>kinase</n> activity within these complexes compared to <n>CheA</n> alone indicate approximately a 50% decrease in the KM for ATP and a 100-fold increase in the Vmax .
23031589987>Thyrotropin-induced expression of a gene for a ribosomal protein related to the <n>trk oncogene</n> .
16911848923><n>Gap b3</n> consists of two polypeptide chains ( Mr = 110 , 000 and 30 , 000 ) , which seem to be proteolytic cleavage products connected by disulfide bonds from a precursor protein .
16288064112>The observed sequence variation disrupts the first ORF in many <n>Y's</n> while most of the second ORF including the putative <n>helicase region</n> is unaffected .
16950982109>Serum <n>IgG</n> was initially elevated in 6 patients .
113156331754>The cleavage site between <n>VPg</n> and <n>RNA dependent RNA polymerase</n> was predicted to be E445-T446 based on the amino acid sequence analysis of the polyprotein from different sobemoviruses .
67430616510>Twenty-one percent of these patients had neurologic disease that appeared to be responsible for the tinnitus .
81062451261>The indoor radon concentration in the summer ( 1990 ) period ranged between 8 and 81 Bq m-3 , while in the winter ( 1989-1990 ) it ranged between 20 and 143 Bq m-3 for the first year of measurements or between 8 and 92 Bq m-3 in the summer ( 1991 ) period and between 12 and 119 Bq m-3 in the winter ( 1990-1991 ) for the second year of measurements .
17648992369>The model is able to anticipate why the effect of water fluoridation on caries prevalence is most pronounced when caries is diagnosed at cavity level .
50874965363>Coronary arteries--old and new .
10838399154>False positive PET FDG corresponded to lung infection , degenerative bone disease , and reconstruction artifact .
64355656238>These changes were the result of a decrease in afterload : mean aortic pressure fell from 85 + / - 11 . 8 to 68 + / - 19 . 6 mmHg ( p less than 0 . 01 ) and systemic arterial resistance fell from 2 886 + / - 745 to 2 010 + / - 610 dynes / cm-5 / sec / m-2 ( p less than 0 . 01 ) .
111583102120>Furthermore , we showed that <n>ERSF</n> including <n>NF-Y</n> and <n>ATF6alpha and / or beta</n> and capable of binding to <n>ERSE</n> is indeed formed when the cellular <n>UPR</n> is activated .
96040529569>Demographic and clinical data were compared with a control group of 339 healthy age-matched women and with a sample of 224 women with wrist fracture .
13980744619>The gene sequence also identified a 340-nucleotide RNA in total yeast RNA and in purified <n>RNase MRP enzyme</n> preparations .
60350015877>Further observations on resorption in guinea pigs following injections of trypan blue .
32634654306>The <n>murine MHC class I genes</n> , <n>H-2Dq</n> and <n>H-2Lq</n> , are strikingly homologous to each other , <n>H-2Ld</n> , and two genes reported to encode <n>tumor-specific antigens</n> .
78192257918>The introduction of an acidic residue at the second site was essential for suppression of the Asn-285 mutation because Lys-220 and Gln-220 second-site mutants of the Asn-285 mutant showed very low tetracycline resistance . ( ABSTRACT TRUNCATED AT 250 WORDS )
66925176452>The effects of antithrombotic drugs in patients with left ventricular thrombi : assessment with indium-111 platelet imaging and two-dimensional echocardiography .
100825854082>To identify additional <n>non-Sir factors</n> that affect rDNA silencing , we performed a genetic screen designed to isolate mutations which alter the expression of reporter genes integrated within the rDNA .
19231672544>Blood flow velocity waveforms were recorded by pulsed Doppler examination of the fetal internal carotid and middle cerebral arteries using the established transabdominal route as well as a new transvaginal approach .
80628337195>The first 85 nt upstream of the transcription initiation site of the <n>mouse desmin gene</n> , which contain an E box ( <n>E1</n> ) , the binding site of the helix-loop-helix myogenic regulators , are sufficient to confer low level muscle-specific expression .
85094303421>The first involved complementation of a nonphotosynthetic mutant of Chlamydomonas , CC-2341 ( ac-u-g-2 . 3 ) , which has a frameshift mutation in the <n>psaB gene</n> , and selection of photosynthetic transformants on minimal medium .
8861955601>Moreover , the second <n>RCC1-like motif</n> located at the amino-terminus of <n>p619</n> stimulates guanine nucleotide exchange on <n>ARF1</n> and on members of the related <n>Rab proteins</n> , but not on other <n>small GTP binding proteins</n> such as <n>Ran</n> or <n>R-Ras2 / TC21</n> .
29872205782>Subcloning of DNA fragments from the 8 . 5-kilobase ( kb ) insert of pAVO4 defined a 4-kb DNA fragment which contained the <n>functional FBP+ gene</n> and its regulatory region .
1005497655>Spectroscopy of negative ions utilizing multiphoton detachment in a Raman coupling regime .
11335116797>Bandshift experiments demonstrate that <n>BmHR3A</n> binds specifically to <n>RORE</n> ( <n>Retinoic acid-related Orphan receptor Response Element</n> ) -like sequences in the promoters of both genes , thus suggesting a direct role for <n>BmHR3A</n> in regulating the expression of <n>BmGATAbeta</n> and <n>ESP genes</n> during vitellogenesis .
35821844244>Drugs that are transformed via phase II reactions usually do not require dosage adjustment .
13048091944>100 years of dentistry at the Friedrich Schiller University in Jena .
338738269><n>Gamma glutamyl transpeptidase</n> ( <n>GGTP</n> ) activity in the seminal fluid .
117080328153>In addition to that , she received hepatic intra-arterial infusion of levoforinate ( l-LV ) 250 mg and 5-fluorouracil ( 5-FU ) 500 mg for combined multiple hepatic metastases starting on postoperative day 14 , and these medications were administered over 48 hours once weekly by infuser pump .
8816301801>The morphological effects of two snake venoms , N . naja and A . piscivorus , and of the <n>Direct Lytic Factor</n> and <n>Phospholipase-A</n> , compounds purified from N . naja crude venom , were investigated on lung and cremaster vessels of rats .
10694210506>The regional blockade of <n>H1R</n> was observed mainly in the frontal , temporal and anterior cingulate cortices , and the intravenous administration of d-chlorpheniramine as a therapeutic dose ( 2 mg ) blocked over 60% of <n>H1R</n> in the frontal cortices .
92256824586>The frequency of positive <n>anti-GM1 antibody</n> titers in the Guillain-Barre syndrome patients with PEN 19 isolates was higher than that in the Guillain-Barre syndrome and Fisher's syndrome patients without PEN 19 isolates .
79444613624>TG-day and TG-night were 19 . 4 + / - 6 . 1% , 26 . 6 + / - 5 . 3% , ( 750 mm3 < T .
76595294109>We used deletion analysis and transfection assays with reporter gene constructs to examine the transcription control elements in the 5' flanking region of the <n>human EpoR gene</n> .
76961834011>However , there were some properties of <n>Rak</n> that are distinct from <n>Src-like kinases</n> : ( a ) expression of <n>Rak</n> was predominantly in epithelial-derived cell lines and tissues , especially normal liver and kidney , and cell lines of breast and colon origin ; ( b ) <n>Rak</n> does not harbor the NH2-terminal glycine essential for myristylation and membrane localization ; and ( c ) <n>Rak</n> possesses a putative bipartite nuclear localization signal in the <n>SH2 domain</n> , and subcellular fractionation studies revealed that <n>p54rak</n> resides predominantly in the nucleus .
67867569051>The role of DNA rearrangement and alternative RNA processing in the expression of <n>immunoglobulin delta genes</n> .
109405628567>Genomic and functional characterization of the <n>oas gene family</n> encoding <n>O-acetylserine ( thiol ) lyases</n> , enzymes catalyzing the final step in cysteine biosynthesis in Arabidopsis thaliana .
10940413762>The results indicate that the open-section effect decreases the torsional stiffness and stress concentration effects decrease the torsional strength of a long bone with a longitudinal defect .
28708517126>Output of 99mTcO-4 by the parotid gland closely mimicked fluctuations in parotid saliva flow rate .
56420515619>Evaluating dietary department management .
95057339471>A review of studies published between 1983 and 1995 shows that there are some common factors as regards the psychological distress and social and functional limitations this group of patients has to deal with .
40395254713>Plasma and bladder platinum concentration were measured following intravesical DDP , and also histopathological examination , urinalysis , complete blood count and blood chemistry were performed in order to know the toxicity of intravesical DDP .
21633476446>The cDNA sequence has an 813-bp open reading frame ( ORF ) whose predicted amino acid sequence is 97 . 6% identical to the 272 carboxy-terminal amino acids of the <n>human ets-1 protein</n> .
35377218495>Tetrad analysis and mitotic recombination experiments localized the <n>PEP4 gene</n> proximal to <n>GAL4</n> on chromosome XVI .
24278122557>These results support the view that clonidine and 6-OHDA , but not alpha-MD , have central pressor actions in the rat that oppose their antihypertensive action .
63734092608>Lauciello describes a technique for the placement of functionally generated amalgam stops as restorations within mandibular acrylic teeth .
16825092764>Here we present evidence that <n>major IE proteins IE86</n>1 , <n>IE72</n> , and <n>IE55</n> are capable of trans-activating the HIV LTR in a T-cell line , HUT-78 .
105709963383>A phylogenetic analysis with the <n>TK domains</n> from these sequences and a fourth , from a novel <n>scavenger RTK</n> ( all domains comprise the signature for the <n>TK class II receptors</n> ) , showed that they are distantly related to the <n>insulin</n> and <n>insulin-like receptors</n> .
81147028066>Members of the <n>myocyte-specific enhancer-binding factor 2</n> ( <n>MEF2</n> ) family of transcription factors bind a conserved A / T-rich sequence in the control regions of numerous muscle-specific genes .
83863185422>We show that <n>IL-6</n> activates <n>JRE-IL6</n> through an H7-sensitive pathway that does not involve <n>protein kinase C</n> , <n>cyclic AMP-dependent kinase</n> , <n>Ca ( 2+ ) - or calmodulin-dependent kinases</n> , <n>Ras</n> , <n>Raf-1</n> , or <n>NF-IL6</n> ( <n>C / EBP beta</n> ) .
106171268385>Histological analysis showed that the neuronal loss in the DHED-treated group was notably reduced in the hippocampal area ( CA1 ) of ischemic rats and in the dentate gyrus and hippocampal area ( CA1 and CA3 ) of EC-lesioned rats compared with the nontreated group .
97055645674>Expression of the <n>human papillomavirus type 11 E5A protein</n> from the <n>E1E4 , E5 transcript</n> .
15041782117>The next twenty years of prevention in Indian country : visionary , complex , and practical .
91291471759>The <n>Jem</n> peptide sequence shows a 'leucine-zipper' dimerisation motif with limited homology to <n>Fos / Jun</n> and <n>ATF / CREB proteins</n> and several putative phosphorylation sites .
27890625622>We have utilized the <n>human 4F2 heavy chain</n> ( <n>4F2HC</n> ) gene as a model system in studies designed to elucidate the molecular events involved in regulating inducible gene expression during normal human T-cell activation .
12968152032>We cloned the third human gene for the <n>LD78</n> , termed <n>LD78 gamma</n> and the sequence analysis showed that it is a 5'-truncated pseudogene .
15384038834>Moreover , the reconstitution of <n>eUSF</n> and TFIID-depleted transcription complexes with purified protein fractions demonstrate that not only <n>TFIID</n> but also <n>eUSF</n> essentially participates in complex formation even on <n>H5 promoter</n> mutations lacking the TATA-box .
71124716915>Histamine reactivity had returned to normal in half the workers who had left their original factories , but in only one worker who had moved within her original factory .
98588838498>BIAcore analysis gave a Kaff of 4 . 4 x 10 ( 10 ) M-1 for the binding of <n>N-A3</n> to <n>T84 . 1</n> and 2 . 2 x 10 ( 10 ) M-1 for the binding of <n>N-A3</n> to <n>T84 . 66</n> .
114355602692>Together these data imply that the <n>HFV R region</n> acts in the nucleus to modify the cytoplasmic fate of <n>target HFV mRNA</n> .
88619635557>Transcription factor recognition surface on the <n>RNA polymerase alpha subunit</n> is involved in contact with the DNA enhancer element .
117260681330>Rind et al . 's study's main conclusions were not supported by the original data .
74943145106>Thus , transcriptional regulation , splicing , kinase interaction sites , and tyrosine phosphorylation of the <n>LMP2A homologs</n> have been conserved despite significant sequences heterogeneity in the preterminal repeat regions of these human and nonhuman primate EBVs .
115648713263>These results indicate the presence of TATA-unified transcription systems in contemporary eukaryotes and provide insight into the residual need for <n>TBP</n> by all three <n>Pols</n> in other eukaryotes despite a lack of TATA elements in their promoters .
94098219822>The <n>Saccharomyces cerevisiae RAD30 gene</n> , a <n>homologue of Escherichia coli dinB</n> and <n>umuC</n> , is DNA damage inducible and functions in a novel error-free postreplication repair mechanism .
113913032540>Right LHR ( R-LHR ) provided the best interobserver and intraobserver reproducibility .
1006312262>Two-Channel Kondo Lattice : An Incoherent Metal .
71726904781>A limiting factor were disturbances in the system of energy transport ( creatine phosphate , <n>creatine phosphokinase</n> ) and of the calcium pump ( <n>Ca++-ATPase</n> of the sarcoplasmic reticulum , SPR ) , which evidently led to a decrease of the inotropic properties of the myocardium at 70% restriction of coronary blood flow .
10347839204>The IC50 values for rat and dog urinary bladder were 3 . 9 x 10 ( -6 ) M and 3 . 8 x 10 ( -6 ) M , respectively .
86208892155>It is shown that the ( G+C ) -rich element of the <n>aldolase C promoter</n> directs transcription in neuronal as well as in nonneuronal cells .
113713434682>During most of the cell cycle , <n>separase</n> is kept inactive by binding to an inhibitory protein called <n>securin</n> .
79331072717>A comparison of the nucleotide sequence of the <n>p54 gene</n> carried by two virulent ASFV strains ( E70 and E75 ) with that obtained from virus Ba71V showed 100% similarity .
104385937046>The <n>human immunodeficiency virus type-1 ( HIV-1 ) Tat protein</n> regulates transcription by stimulating <n>RNA polymerase</n> processivity .
58795955786>Statistics of the past 5 years .
109346406347>TB bone area ( p < 0 . 001 ) , height ( p < 0 . 01 ) , years in present colony ( p = 0 . 03 ) , and menses ( p < 0 . 01 ) predicted TB BMC .
104788447580>Cotransfection of the coactivator <n>CREB-binding protein</n> relieved the transcriptional repression of <n>PPARalphawt</n> by <n>PPARalphatr</n> , suggesting that the dominant negative effect of <n>PPARalphatr</n> might occur through competition for essential coactivators .
6643201946>Looming detectors in the human visual pathway .
112807999599>In contrast , <n>exogenous PTHrP1-34 and 1-86 peptides</n> did not significantly affect <n>IL-8</n> production ; moreover , <n>PTHrP-neutralizing antibodies</n> did not inhibit the production of <n>IL-8</n> by transfected <n>PTHrP</n> .
61559675978>All radiologists using the machine found that the reporting terminal was simple to operate , but found that reporting abnormalities caused an increased effort and took a longer time .
10362897223>Results : Transpulmonary passage of contrast occurred in sufficient amounts to enhance the intensity of the Doppler signal significantly , but the duration of this effect was short .
10619169564>Rams were weighed and testis size was estimated by orchimetry at each time period .
103665038393>Although the <n>terminase</n> apparently interacts with this <n>gp20 portal peptide</n> , polyclonal antibody against the portal peptide appears unable to access it in the native structure , suggesting intimate association of <n>gp20</n> and <n>gp17</n> possibly internalizes <n>terminase regions</n> within the portal in the packasome complex .
114958331376>Simulating the impact during human jumping by means of a 4-degrees-of-freedom model .
30466553764>We report a prevalence study of the best visual acuity in the affected eye of 100 selected patients with herpetic keratitis seen during a two-year period .
92751648353>The m7GpppN cap structure of eukaryotic mRNA is formed cotranscriptionally by the sequential action of three enzymes : <n>RNA triphosphatase</n> , <n>RNA guanylyltransferase</n> , and <n>RNA ( guanine-7 ) -methyltransferase</n> .
105313406161>R . , Fleischmann , R . , Venter , J .
74761645905>In addition , two-dimensional nuclear magnetic resonance studies with F17A , K13Q , F15Y and F27Y revealed that the mutants have the same overall structure as the <n>wild-type CspB protein</n> .
86343575612>The extraction recovery of Amphotericin B from the cerebrospinal fluid is higher than 90% over the entire linear range .
110549706019>The plexiform neurofibroma and multiple localized neurofibromas are characteristic of <n>NF1</n> .
96527363920>In addition , we find that <n>E2F-1</n> can cause apoptosis in <n>p53- / -</n> tumour cells and further <n>p300</n> , which also functions as a co-activator for the <n>E2F / DP heterodimer</n> , enhances the apoptotic activity of <n>E2F-1</n> .
12026161851>Following retransfusion , the affected epithelial lining appeared greatly distended over the oedematous lamina propria , with almost complete loss of structural detail .
85520821652>Here we report that the proline-rich region of <n>CAP</n> is recognized by the <n>SH3 domains</n> of several proteins , including the <n>yeast actin-associated protein Abp1p</n> .
8263933873>Molecular cloning of a <n>P-type ATPase gene</n> from the cyanobacterium Synechocystis sp .
91240547577>The prognosis of seven patients who received ABSCT was significantly better than that of 13 patients who received conventional therapy alone .
105160117824>In the work reported here , we used peptide mapping , mass spectrometry , and site-directed mutagenesis to identify two sets of <n>pAP</n> phosphorylation sites .
7626806465>The <n>RAT3 gene</n> encodes an 1157-amino acid protein without similarity to other known proteins .
99188425864>The high conservation of the 3' terminus suggests that this region directs the assembly of proteins required for the initiation of RNA replication .
66150534052>Sixteen patients were studied within 24 hours of resuscitation and all showed depressed right ventricular ejection ( RVEF ) and / or an increased end-diastolic volume ( RVEDVI ) .
103959082905>This is predicted to encode a 315-residue protein containing seven hydrophobic helical regions and a 17 amino acid motif characteristic of the <n>R7G family</n> of <n>G-protein coupled membrane-bound receptors</n> .
70652069504>In 10 control sheep mean plasma TXB2 concentration increased from 0 . 39 ng / ml prebypass to about 1 . 1 ng / ml at 8 and 16 min of bypass .
9765466822>J .
93111641727>The distributed current density J is calculated within the volume defined by the motor unit .
87493933562>The <n>PI3K_68D cDNA</n> encodes a protein of 210 kDa , which lacks sequences implicated in linking p110 <n>PI 3-kinases</n> to <n>p85 adaptor proteins</n> , but contains an amino-terminal proline-rich sequence , which could bind to <n>SH3 domains</n> , and a carboxy-terminal C2 domain .
62968335898>Two mutations that affect <n>larval cuticle protein gene</n> expression in the 2 / 3 variant Drosophila melanogaster strain were investigated .
5877915781>Nursing of patients with gynecological diseases .
11032677867>Prominent findings were chronic pancreatitis with acinar and ductal plugs , granulomatous and necrotizing peripancreatic steatitis , degenerative myopathy , testicular atrophy , candidiasis and bacterial necrotizing glossitis .
100712122566>Nipponbare as well as O . australiensis .
98910922393>We show that the <n>Sm-binding site</n> and stem-loop III structures are necessary for correct 3'-end formation .
90621306833>Relief from autoinhibition and a subsequent 10-60-fold increase in V ( max ) have been observed upon <n>N-SH2 domain</n> engagement by a specific phosphotyrosyl ligand or upon deletion of the <n>SH2 domains</n> to yield the catalytic <n>PTPase domain</n> .
107729778577>Viral cell-to-cell movement of <n>PVX CP mutant</n> was complemented in Nicotiana tabacum cv .
38785853925>The percentage RFR reduction at the end of CPB showed significant correlation with 1 ) CPB duration ( r = 0 . 49 ) , 2 ) oxygen flow rate index ( OFRI ) , i . e . flow / min in the bubble oxygenator / m2 bsa ( r = 0 . 38 ) , and 3 ) blood flow rate index ( BFRI ) , i . e . average volume of blood pumped through the heart-lung machine / min CPB time / m2 bsa ( r = 0 . 51 ) .
61422795960>Risk of HTLV infection in patients on haemodialysis .
82267765826>Unfolding can be described by a two-state process since a ratio of delta Hcalorimetric to delta Hvan't Hoff equals 0 . 96 .
115480277135>A proposal of 50 performance indicators divided into five different groups is presented here , namely structural indicators , operational indicators , water and service quality indicators , personnel indicators and economic indicators .
18488713298>This study tested the hypothesis that sodium channel blocking drugs selectively prolong the late potential , or terminal low amplitude signal , portion of the signal-averaged QRS complex and that prolongation of the late potential would correlate with slowing of ventricular tachycardia .
30613839605>The in vitro activity of mecillinam and amoxicillin / clavulanic acid against Escherichia coli strains producing <n>beta-lactamases</n> of the <n>TEM-1</n> , <n>Oxa-1</n> and chromosomal type were studied using the broth and agar dilution technique .
105560285582>The <n>cop region</n> also harbors a region of plasmid incompatibility , <n>inc</n> , encompassing a stem-loop structure , the <n>repA promoter</n> , <n>Prep</n> , as well as two distinct <n>RepA binding sites</n> , <n>BD-1</n> and <n>BD-2</n> .
105056946928><n>IL-12</n> production was correlated with C3a concentration measured at the outlet of hemodialyzer after 15 min of dialysis ( r = 0 . 69 , P < 0 . 01 ) .
10964833793>Only two of 27 participants ( 7 . 4% ) with definite POAG had been previously diagnosed and treated , and 66 . 7% of the previously undiagnosed had IOP less than 22 mmHg .
86611016922>DNA sequence analysis reveals that the gene encodes a protein highly homologous to <n>rat CRP1</n> .
96929656537>When cysteine is scanned through the helices , characteristic repeating patterns of solvent exposure and burial are observed .
82646172077>Recombinant expression of a chimeric <n>EGFR / ErbB-3 receptor</n> in NIH 3T3 fibroblasts allowed us to investigate cytoplasmic events associated with <n>ErbB-3</n> signal transduction upon ligand activation .
62728449557>Replicating simian virus 40 ( SV40 ) chromosomes were found to be similar to other eukaryotic chromosomes in that the rate and extent of <n>micrococcal nuclease</n> ( <n>MNase</n> ) digestion were greater with replicating than with nonreplicating mature SV40 chromatin .
79512352340>One gene appears ubiquitously expressed while the other is prominently expressed in muscle .
30751544722>Recurrence of oxalate deposition in a renal transplant during ciclosporin A therapy .
76397039647>As retinoic acid and thyroid hormone are frequently involved in developmental regulatory processes , it is possible that this element may be important in the process of islet cell differentiation .
10895417721>We have shown that the epidural ( EPI ) delivery of morphine encapsulated in multivesicular liposomes ( DepoFoam drug delivery system ) produces a sustained clearance of morphine and a prolonged analgesia .
103837642398>The results of these studies support a model in which <n>VirB4 dimers</n> or homomultimers contribute structural information for the assembly of a transenvelope channel competent for bidirectional DNA transfer , whereas an ATP-dependent activity is required for configuring this channel as a dedicated export machine .
107787404168>The <n>C-terminal Cdk2</n> truncations , however , were non-functional in these strains and thus dependent for activity on the <n>pho85 coding region</n> which remained in the <n>mutant pho85</n> : : <n>HIS3 chromosomal locus</n> .
60972855922>It is concluded that haloperidol selectively reduced the animal's capacity to 'programme non-stimulus directed motor behaviour' .
87767928764>Sleep was determined again for an additional 3 days and 6 hours .
84433391092>Histochemical localization of <n>GUS</n> revealed promoter function in leaf epidermis , mesophyll and vascular bundles , in the cortex and vascular cylinder of the root .
112665583413>We show here that the in vitro transcription extract contains a binding activity that is specific for the initiator element and thus may participate in recruiting <n>RNA polymerase II</n> to the <n>SL RNA gene promoter</n> .
82997252157>The inserted region , which represents an intron in brain and muscle , is expressed in the tumor cell lines either as a "readthrough" form or with 78 residues deleted from its 5' end .
84456555580>Localization of the insertion locus in the yeast genome and complementation studies with the temperature-sensitive mutant indicate that the two mutations are allelic .
91778575743>The conditions for obtaining titanium dioxide from the substrates titanium tetrachloride and oxygen and applying this to a surgical stainless steel of the type 316L by the plasma assisted chemical vapour deposition method have been determined .
86494033400>The growth defect of a <n>reg1 reg2</n>1 <n>double</n>1 <n>mutant</n>1 is alleviated by a loss-of-function mutation in the <n>SNF1-encoded protein kinase</n> .
78872261700>When combined with serum <n>ferritin</n> and <n>hemoglobin</n> determinations , the serum <n>transferrin receptor</n> assay is a valuable addition in epidemiologic surveys because it provides a quantitative measure of functional iron deficiency and it distinguishes true IDA from the anemia of chronic disease .
104978005282>The MMPI-A ( Butcher et al . , 1992 ) , like the older MMPI ( Hathaway & McKinley , 1983 ) , distinguishes between anorexia and bulimia .
95785701197>In this study , to characterize the gene for <n>protein Z</n> , its organization and structure were determined by a combination of PCR amplification of leukocyte DNA and isolation of phage clones from a human genomic library .
28069161471>A genomic DNA clone encoding <n>oryzacystatin</n> ( <n>Oc</n> ) , a <n>cysteine proteinase inhibitor</n> ( <n>cystatin</n> ) of rice , was isolated from a lambda EMBL3 phage library constructed with <n>Sau3AI</n> partial digests of rice chromosomal DNA , by screening with an <n>oc cDNA</n> as a probe .
91712397475>Surprisingly , the RXR-specific ligand 9-cis-retinoic acid induced binding of <n>SRC-1</n> to the <n>RXR component</n> of the TRE-bound heterodimer .
103404479551>The average coefficients of correlation were 0 . 9998 and 0 . 9993 for the QMF and the QIT system , respectively .
64942976376>The results imply that kindling does not produce its facilitating effect on acquisition of HPC SS by removing a disruptive effect of the stimulation .
77538373796>When RNA encoding the tail domain of <n>desmoglein</n> was coinjected with <n>plakoglobin RNA</n> , both the dorsalizing effect and nuclear accumulation of <n>plakoglobin</n> were suppressed .
78137864304>Two related cDNAs were isolated that encode proteins that recognize the <n>XMyoDa TATA motif</n> .
112274848263>Fluorimetric determination of methylmercury as an ion-association complex with rhodamine B in the presence of iodide .
9328343726>Expression from this element is regulated by a heteromeric protein complex containing ubiquitous ( i . e . the <n>E2A-</n> and <n>HEB-encoded proteins</n> ) and islet-enriched members of the <n>bHLH family</n> .
91237874780>The electromyographically recorded responses consisted of an early R1 response in the orbicularis oculi muscle ipsilateral to the side of stimulation , a bilateral late response ( ipsilateral R2 and contralateral Rc ) and a third , R3 response , in the ipsilateral orbicularis oculi muscle .
88778181161>The amplification was achieved using two primers which correspond to <n>TRH progenitor sequence</n> ( <n>Lys / Arg-Arg-Gln-His-Pro-Gly-Lys / Arg-Arg</n> ) .
67203716493>Pilot study of blood coagulation in gout patients .
94261833677>The well-known <n>Rel / NF-kappaB family</n> of vertebrate transcription factors comprises a number of structurally related , interacting proteins that bind DNA as dimers and whose activity is regulated by subcellular location .
69936605937>Contractile responses to norepinephrine , serotonin and potassium ( K+ ) and relaxant responses to isoproterenol and papaverine were studied in vitro with spirally cut thoracic aortic strips from aortic coarcted hypertensive rats ( AHR ) 2 , 6 , 14 and 28 days postoperatively and compared to time-matched , sham-operated normotensive controls .
8825554579><n>Tristetraprolin</n> ( <n>TTP</n> ) is the prototype of a group of potential transcription factors that contain two or more unusual CCCH zinc fingers .
75630762840>These intron chimeras show that peripheral sequences and the elements that define the splice sites are adequate for self-splicing activity but that the central portions containing the catalytic cores of <n>ai4</n> and <n>bi4</n> are deficient ; these cores are the likely targets of the splicing proteins .
13344284896>Km and Vmax for two substrates , <n>src-related peptide</n> and poly ( Glu , Tyr ) ( 4 : 1 ) , were 2 . 4 mM and 2 . 5 mumol min-1 mg-1 and 0 . 26 mM and 1 . 2 mumol min-1 mg-1 , respectively .
96930359911><n>Human ULK1</n> , a novel <n>serine / threonine kinase</n> related to <n>UNC-51 kinase</n> of Caenorhabditis elegans : cDNA cloning , expression , and chromosomal assignment .
10683259559>Sulfhydryl titration with iodoacetamide , monitored by quantitating the residual thiols after reaction with a maleimide derivative of biotin , revealed a striking difference in the apparent pK ( a ) values of the cysteines at the two splice junctions .
75114965709>High plasma concentrations of soluble <n>E-selectin</n> were closely associated with multiple-organ dysfunction and death .
98910468143>In such a manner , activated <n>PKR</n> inhibits cell growth and induces apoptosis , whereas disruption of normal <n>PKR</n> signaling results in unregulated cell growth .
1035457210>When a tumour is present nipple discharge is of little importance for the diagnosis and treatment .
255573209>When the CO2 content reached 9 Vol% the animals became apathic and lost body weight .
89956523141>The results demonstrate that ( i ) no intact capsids were assembled when the full-length or a truncated ( missing the C-terminal 65 amino acids ) <n>UL80 . 5 protein</n> was tested ; ( ii ) when the C-terminal 65 amino acids of the <n>UL80 . 5 protein</n> were replaced with the C-terminal 25 amino acids of the <n>UL26 . 5 protein</n> , intact capsids were made and direct interaction of the <n>UL80 . 5 protein</n> with <n>VP5</n> was detected ; ( iii ) assembly of intact capsids was demonstrated when the sequence of the last 12 amino acids of the <n>UL80 . 5 protein</n> was changed from <n>RRIFVA ALNKLE</n> to <n>RRIFVAAMMKLE</n> ; ( iv ) self-interaction of the scaffold proteins is mediated by sequences N terminal to the maturation cleavage site ; and ( v ) the <n>UL26 . 5</n> and <n>UL80 . 5 proteins</n> will not coassemble into scaffold structures .
112072699554><n>Anti-nucleolin mAb</n> was used to confirm the antigenic properties of this <n>p95 component</n> .
88743998832>Sixty days after the intervention , twitch and tetanic tensions remained dependent upon the extracellular Ca2+ concentration ( [ Ca ] o ) both in groups A and B .
58371695773>Methoxyflurane and renal function .
39988134660>In the present experiments , we investigate the role played by the temporal pattern of neural activity during the ontogeny of frequency tuning in the mouse central auditory system .
107931435750>Because the mutant defective in DNA binding also fails to stimulate <n>Abf1 ARS1</n>1 DNA-binding activity , our results suggest that <n>Cdc6</n> DNA-binding activity may play a pivotal role in the initiation of DNA replication .
77062734521>Transcriptional regulation of the <n>vacuolar H ( + ) -ATPase B2 subunit gene</n> in differentiating THP-1 cells .
118455471728>Potential treatments include dobutamine , KATP channel activators , and 21-aminosteroids .
68303517913>According to Sugiura's classification , they consisted of Type Ia in 63% , Type Ib in 11% , Type II in 11% , and Type III in 16% .
110022362321>METHODS : In the current study the authors reported on PPB cases from a national retrospective search performed in 18 Italian Associations for Pediatric Hematology and Oncology centers .
11781531628>D .
98116951019>These results indicate that HIV-1 <n>Gag sequences</n> can influence the viral PR-mediated processing of the MuLV <n>TM Env protein p15</n>1 <n>(</n>1 <n>E</n>1 <n>)</n>1 .
91825277649>Consistent with its role in <n>p53</n> ubiquitination , <n>mE6-AP</n> was found both in the nucleus and cytosol , while <n>Nedd-4</n> was found only in the cytosol .
73729286515>Tests of the method indicate ( 1 ) the Mossbauer source can be placed on the basilar membrane without altering the signal-transmission properties of the cochlea , and ( 2 ) the source adheres to the basilar membrane .
82898345279>When expressed alone in test cells , <n>Atr-I</n> is unable to bind <n>TGF-beta</n> , <n>activin</n> , or <n>bone morphogenetic protein 2</n> .
83006052555>One of these elements , the <n>homeodomain-binding element</n> , was identified to mediate negative regulation .
81395428389>The mutations did not affect the repression of <n>CPA1</n> by arginine .
81125268088>Increasing the extracellular calcium concentration enhanced detrusor contractility in a dose-dependent manner in both control and obstructed bladders .
77412552568>These six districts have an area of 34 , 000 km2 and hold a population of 30 million .
93331687227><n>Anti-hepatitis A</n> virus ( HAV ) titer after vaccination was measured in 83 HIV-positive and 39 HIV-negative men .
28740783555>An endometrial luteal phase deficiency was detected in 15 ( 30% ) of aborting patients .
81738148145>These viruses depend on the host cell machinery for their existence , and interference with these processes typically interferes with other important host physiology .
88983364825><n>RNase</n> protection analysis of two <n>rRNA fragments</n> whose genes are adjacent provided evidence for a polycistronic transcript containing sequences from both , as well as separate small RNAs .
116878691538>A 38-year-old woman with ulcerative colitis subsequently developed sarcoidosis .
14868367164>Patients receiving VPA showed differences in attention , visuomotor performance , verbal span and sensory discrimination tasks at T1 , in visuomotor performance at T2 and in spatial span at T3 , whereas no differences were detected at T4 .
29264993634>Recently , an electrical-mechanical analog model of heat flow within the brain has been developed from which an expression for CBF has been derived : CBF = Cb / ( tau rho c ) where tau is the thermal decay constant , rho is the density of blood , and c is its specific heat .
74364597549>It is suggested that a raised hydroxykynurenine / hydroxyanthranilic acid ratio does not necessarily indicate vitamin B6 deficiency but may represent a nonspecific response of tryptophan metabolism to stress .
96709129637>"Complex partial" seizures .
11072388905>Acute feasibility and safety of a smoking reduction strategy for smokers with schizophrenia .
115997971527>RESULTS : A novel gene was cloned .
76241196846>To compare the <n>PAX3</n> and putative <n>PAX3-FKHR transactivation domains</n> , we fused C-terminal test fragments to the heterologous <n>GAL4 DNA-binding domain</n> and tested activation of a reporter gene co-transfected into four cell types .
81871775757>A single amino acid change in the <n>CPY vacuolar sorting signal</n> prevents this interaction .
78523613256>Removal of PDMP from the cell medium resulted in reversal of the cell cycle changes , with cells re-entering the S phase .
104911872359>The <n>phosphotransferase</n> system ( PTS ) of Streptomyces coelicolor identification and biochemical analysis of a <n>histidine phosphocarrier protein HPr</n>1 encoded by the gene <n>ptsH</n> .
78621413403>One member of this family , <n>RFX1</n> , is a transcription factor for a variety of viral and cellular genes .
81080998083>Evaluation of desmopressin for dental extractions in patients with hemostatic disorders .
47887015164>Combination of 3 multiple primary malignant and benign tumors of the breasts and uterus .
93261634213>RESULTS : The standardised mortality ratio ( SMR ) for all malignant neoplasms was 94 ( 95% CI 74 to 118 ) .
85383826899>Erythrocyte AA in FO+EPO-supplemented infants remained low and below breast- and placebo formula-fed levels .
23498278319>A semiautomatic digital system ( Videoplan 2 ) was used .
23837713035>On histologic examination the cuboidal epithelium of the mucous membrane was found to be changed into columnar epithelium , with uneven distribution of enlarged nuclei in the vacuolized cytoplasm .
27235033412>Swim-over : an alternative method for harvesting motile spermatozoa .
98226472850>The <n>rat aldolase C gene</n> encodes a glycolytic enzyme strongly expressed in adult brain .
109754651790>The human cDNA clone NFBD1 ( previously designated KIAA0170 ) encodes a novel protein ( 2089 amino acids in length ; calculated molecular mass 226 , 440 D ) with possible <n>BRCT domains</n> at its carboxy terminus ( amino acid residues 1894-2089 ) .
81998788173>The effects of systemic glucose concentration on brain metabolism following repeated brain ischemia .
98117305031>Mechanism of <n>interferon</n> action : identification of essential positions within the novel <n>15-base-pair KCS element</n> required for transcriptional activation of the <n>RNA-dependent protein kinase pkr gene</n> .
84887003210>The strategies by which hepatitis B and hepatitis D can be diminished and eventually eliminated are : immunization , measures to prevent exposure to infective blood or blood derivatives and education ( in particular awareness that hepatitis B is a sexually transmitted disease ) .
83247928304>A single five minute period of rapid atrial pacing fails to limit infarct size in the in situ rabbit heart .
10610716256>Finally , three new missense mutations , <n>E138V</n> , <n>R254G</n> , and <n>P362R</n> , were identified in the <n>human AC gene</n> from FD patients .
117719791611>Although the spatial and temporal variability of LDF signals evoked by cerebrocortical microflow is in the same range as with other methods and in other organs , LDF cerebrocortical mapping is restricted by the large temporal and spatial heterogeneity of the cerebrocortical vasculature .
34171044115>Taken together , the results suggest that chlorphentermine may be capable of producing dual stimulus effects in animals .
75740642061>However , 2 minimum alveolar concentration anesthesia did significantly decrease the calculated VE at a PCO2 of 60 mmHg ( from 7 . 4 + / - 1 . 2 to 4 . 0 + / - 0 . 6 l . min-1 ) , indicating a rightward shift in the response relationship .
111423801377><n>Nuclease</n> probing and structure-directed mutagenesis revealed that the <n>105-nt TE</n> ( <n>TE105</n> ) forms a cruciform secondary structure containing four helices connected by single-stranded regions .
8960827258>These results suggested that the GG motifs contributed to the cell-specific transcription of the <n>human insulin gene</n> in association with the binding of the sequence-specific nuclear factor .
76369845088>To investigate the potential role of <n>SP1</n> , we examined nuclear extracts from HCMV-infected cells .
104469983575>In contrast , the differentiation of neoplastically transformed cells does not repress mitogenic responsiveness or <n>junB</n> or <n>c-fos</n> inducibility .
15448547258>Of the drugs orally administered , WR-168643 was the best protector with a DMF of 1 . 51 .
9755191434>Here , we report that <n>swa5-1</n> is a new temperature-sensitive allele of the <n>clathrin heavy chain gene</n> ( <n>chc1-5</n> ) , which carries a frameshift mutation near the 3' end of the <n>CHC1</n> open reading frame .
35789489065>Artificial ventilation was conducted using a tidal volume of 10 ml X kg-1 and a rate of 10 to 12 c X min-1 .
90997459864>Active complexes eluted at a higher molecular weight than inactive complexes , were relatively deficient in both <n>p21</n> and <n>p27</n> , and contained <n>Cdk2</n> with increased threonine 160 phosphorylation , consistent with a mechanism of activation of <n>cyclin E-Cdk2</n> involving both reduced <n>CDK</n> inhibitor association and CDK-activating kinase-mediated phosphorylation of <n>Cdk2</n> .
38904864550>Pancreaticoduodenal lymph node enlargement , regardless of cause , has been a source of imaging confusion because of its propensity to mimic pancreatic malignancy yet not cause biliary obstruction .
95823313780>The 5'-flanking region , from nucleotide -837 to -336 , contains TATA and inverted CAAT boxes as well as <n>GATA-1 / SP1</n> erythroid-specific cis-acting regulatory elements .
79366359093>Mutation of <n>KRKR</n> to <n>NGER</n> retains <n>MO15</n> in the cytoplasmic compartment , whilst the wild-type protein is detected exclusively in the nucleus .
62235865017>However , when combined with mitomycin C given with 1 to 5-days interval , the concurrent administration of SPG prolonged significantly the life-span of the tumor-bearing mice .
118529071738>The equilibrium phosphorus content ( EPC0 ) of surface soil was generally higher than the SRP content of drainage water , at one farm by 1 order of magnitude .
6413958887>When blood samples of patients with hyperbilirubinemia were analyzed , direct measurement of ZPP by this fluorimeter yielded significantly higher levels than did an alternate extraction method .
104469988517>Transformation blocks differentiation-induced inhibition of <n>serum response factor</n> interactions with <n>serum response elements</n> .
69666786744>The monoexponential rate of clearance of tracer--obtained from the portion of the residue-detection curve reflecting metabolism of fatty acid incorporated into neutral lipids--correlated directly with induced changes in tension-time index after injections into the left atrium ( r = 0 . 96 , n = 12 ) , right atrium ( r = 0 . 86 , n = 14 ) , and ear vein ( r = 0 . 93 , n = 14 ) .
8022212837>Using a previously published two-frequency ( AC excitation ) three-electrode method , the admittance locus plot ( ALP ) in the low-frequency region ( < 1000 Hz ) has been shown to be very well approximated by a straight line and can be described with frequency-independent parameters ; phase angle alpha pi / 2 , conductance at extrapolated zero frequency G0 = 1 / R0 , and ion relaxation time tau .
13138944681>A rather similar pattern of results was obtained with respect to <n>LMP2B mRNA</n> expression , such transcripts being detectable only in a subset of tumors , and then at apparently low levels .
45800445037>Temporal relationships and the development phase affected .
76238075462>To dissect these mechanisms , wild-type and <n>mutant Raf-1 proteins</n> were studied in an in vitro system with purified plasma membranes from v-Ras- and v-Src-transformed cells ( transformed membranes ) .
96472406230>The influence of <n>p53</n> on cytokine-triggered <n>Janus kinase-STAT</n> signaling was investigated in human hepatoma Hep3B cell lines engineered to constitutively express the temperature-sensitive <n>Val135 mutant of p53</n> .
10628490449>Anatomy of the uterine artery .
10867496681>Neurofibromatosis of the breast in a patient with Morbus von Recklinghausen .
115838805269>Endovascular aneurysm repair with the AneuRx stent-graft is safe , but is it effective ?
1086583848><n>Vascular endothelial growth factor</n> ( <n>VEGF</n> ) , a potent agonist secreted by virtually all cells , controls migration and division of vascular endothelial cells .
87516356834>This caused severe cortical damage and neuronal loss in hippocampus subfields CA1 , CA3 , and hilus .
20346698571>Only the 3 . 0-kb transcript was detected in adult tissues , where its expression was restricted almost exclusively to the central nervous system .
13213374229>A third prominent component of apparent molecular mass 16 kDa displayed several properties , including ability to bind 45Ca2+ , that are characteristic of the regulatory ( B ) subunit of <n>mammalian calcineurin</n> and was recognized by an antiserum raised against <n>bovine calcineurin</n> .
11038042876>Escalation to 180 mg / m2 was to be carried out if white blood cell nadir count was > 2 . 0 x 10 ( 9 ) / l and platelet nadir count was > 75 x 10 ( 9 ) / l .
31860917695>Change in <n>plasma cystyl aminopeptidase</n> ( <n>oxytocinase</n> ) between 30-34 weeks' gestation as a predictor of pregnancy-induced hypertension .
9852769842>Preflight , inflight , and postflight exercise response tests were conducted on the astronauts of the second Skylab mission ( Skylab 3 ) as part of an evaluation of physiological adaptation to long-term weightlessness .
9550919320>When data were expressed in a cumulative manner , the response to intravenous adenosine 3 mg , 6 mg , 9 mg and 12 mg in the 24 episodes of PSVT were 5 episodes ( 21% ) , 16 episodes ( 67% ) , 20 episodes ( 83% ) and 20 episodes ( 83% ) respectively .
48101314231>Letter : <n>Aryl hydrocarbon hydroxylase</n> and smoking .
56840812857>Measurements of activity with the radioprotective chamber VA-K-254 of the osimeter VA-J18 .
77830642698>Serial followup strength data for 2 patients were compared to change in <n>creatinine kinase</n> ( <n>CK</n> ) levels .
112743576538>On the other hand , forced overexpression of the wild type , but not the kinase-inactivated mutant of <n>nm23H1</n> , converted the GDP-bound forms of <n>Rac1</n> , <n>Cdc42</n> , and <n>RhoA</n> to their GTP-bound forms in vitro by its <n>nucleoside diphosphate kinase</n> activity , but <n>nm23H1</n> alone apparently did not produce the GTP-bound form of these <n>GTPases</n> in vivo .
85618978229>Mobility and supershift assays demonstrated that <n>upstream stimulatory factor</n> ( <n>USF</n> ) and <n>Sp1</n> bind to the former elements and competition experiments confirmed that <n>CREB / ATF</n> and <n>AP-1</n> bind to the <n>CRE / TRE element</n> .
106840693747>The results showed that MIP , MMIF , FIC , Wimax , P0 . 1 and minute ventilation ( Vr ) were significantly increased after administration of methylphenidatum and aminophylline .
31101197655>During BH the ventilator was disconnected and a bias flow of 50% O2 at 4-5 l / min was delivered through the side ports of a small catheter whose tip was positioned 1 cm cephalad of the carina .
17486301695><n>Growth factor</n> stimulation of cells causes the phosphorylation of the <n>c-Myc transcriptional activation domain</n> at Ser62 within a proline-rich region that is highly conserved among members of the <n>Myc family</n> ( Alvarez , E . , Northwood , I . C . , Gonzalez , F .
114106648030>In this report this technique was applied to human breast carcinoma MDA-MB231 cells overexpressing <n>human MPG</n> in order to assess whether up-regulation of the initial step in BER alters the activity of selected other BER ( <n>hOGG1</n> and <n>APE / ref-1</n> ) or direct reversal ( <n>MGMT</n> ) repair activities .
110427036691>When BFDS was taken as the reference , W / A Z scores showed consistent positive increments , from birth in girls and 1 mo in boys .
63142769989>Plasmids for the cloning and expression of full-length double-stranded cDNAs under control of the <n>SV40 early or late gene promoter</n> .
10992983828>Regarding "the relation between sexual orientation and penile size , " by A .
13397731964>A total of 281 patients were divided into groups according to their clinical diagnosis and were examined using capnography , spirometry and blood-gas analysis .
8621719859>A substantial fraction of <n>Cbl</n> was constitutively associated with <n>Grb2</n> and this interaction was mediated by <n>Grb2 SH3 domains</n> .
93432229601>The <n>AGM and NIH / Swiss mouse CCR5 proteins</n> are 97 . 7 to 98 . 3% and 79 . 8% identical to the human protein , respectively .
103972571205>Mutagenesis of the <n>CDE / CHR elements</n> and <n>Sp1 sites</n> in this region , alone or in combination , reduced transcriptional activity by 40-60% in asynchronously growing cells and abolished cell cycle periodicity in G2-M-synchronized cells .
80723522697>All our patients had polyps , 23 ( 54% ) had asthma , 12 ( 27% ) had aspirin sensitivity , 20 ( 65% ) had eosinophilia , and 9 ( 69% ) had increased total <n>IgE</n> levels .
8728040399>Differential activation of the <n>extracellular signal-regulated kinase</n> , <n>Jun kinase</n> and <n>Janus kinase-Stat</n> pathways by oncostatin M and <n>basic fibroblast growth factor</n> in AIDS-derived Kaposi's sarcoma cells .
104005936964>By contrast , <n>PvirE</n> or <n>Plac promoter constructs</n> yielded functional <n>VirE2</n> only if <n>virE1</n> was coexpressed with <n>virE2</n> .
95715634741>PURPOSE : To introduce an image analysis of the cornea in photorefractive keratectomy ( PRK ) for preoperative and early postoperative determination of changes in the condition of the cornea .
110241825000>Normal <n>alpha1 ( I ) collagen mRNA</n> showed no significant reduction when AR or IR was expressed from the pHbetaAPr-1-neo vector and a small ( 10-20% ) but significant reduction when either <n>ribozyme</n> was expressed from the pCI . neo vector .
20045213543>Patients with apparently minor CT abnormalities may have significant epidural disease .
40697564748>Diagnosis : progressive multifocal leukoencephalopathy .
29381855346>Transformed cell lines expressing solely <n>E1a</n> or <n>E1a</n> and <n>E1b gene products</n> derived from these viruses display enhanced anchorage-independent growth at 37 degrees C versus 32 degrees C and display a cytoskeletal architecture resembling untransformed fibroblastic CREF cells .
30648111026>The amino acid sequence of the S . aureus peptide carrying the phosphoryl group was found to be <n>Gln-Val-Val-Ser-Thr-Phe-Met-Gly-Asn-Gly-Leu-Ala-Ile-Pro-His-Gly-Thr-Asp- Asp</n> .
95064392335><n>PKC-gamma</n> , which is not present in keratinocytes , also induces <n>involucrin gene</n> expression in a TPA-independent manner , when introduced into SVHK cells .
84465796136>The exogenous <n>fos gene</n> was rapidly induced to maximal levels within 1-2 hr of estrogen addition .
107068873037>In addition , expected decreases in <n>ATIC</n> enzymatic function in ATIC-ALK-containing lymphomas may render these tumors more sensitive to antifolate drugs such as methotrexate .
14234542043>Examination of ANCA is not only a significant contribution towards a more accurate diagnosis of renal vasculitis , but also an indicator of the activity of the disease and thus of the effectiveness of immunosuppressive treatment .
114732547077><n>NaeI</n> , a novel <n>DNA endonuclease</n> , shows <n>topoisomerase</n> and <n>recombinase</n> activities when a Lys residue is substituted for Leu 43 .
78761915856>Expression of <n>class IV ADH mRNA</n> was detected in human stomach but not liver .
74280377791>Within the 3' terminal 50 nucleotides , the <n>mouse mt 12S rRNA</n> contains a potential 10 bp hairpin structure and a sequence of 15 consecutive nucleotides common to the RNA of the small ribosomal subunit in all systems , but does not contain the mRNA binding site ( <n>ACCUCC</n> ) found in E . coli and corn chloroplast rRNAs .
10449072298>The second goal was to ascertain the somatotopic arrangement of the GPi in PD .
109199713727>In addition to its effect in augmenting the neutrophil response to eccentric exercise , vitamin E causes a greater increase in circulating <n>creatine kinase</n> activity , perhaps indicating increased skeletal muscle repair .
78738767223>The NR2 hybrid is a powerful tool for the mapping of new probes of this region , as well as for obtaining new informative probes specific for the deletion by subtractive cloning of the region .
82882404263>The sequence similarity has suggested that <n>SCG10</n> and <n>stathmin</n> have been derived from structurally and evolutionarily related genes .
1581577784><n>PSI-G</n> and <n>PSI-K</n> probably have evolved from a gene duplication of an ancestral gene .
91503349100>Each sample was analysed as soon as possible , and repeated 15 , 30 , 60 and 120 min after sampling .
95198285965><n>Chimaeric VP16-E2 molecules</n> suggest that the epithelial specific transcriptional activation of the BPV-4 LCR promoter is mediated by the <n>E2 transactivation domain</n> .
91266221179>The pigment intensity of both melanized colonies and appressoria of CAL transformants was weaker than that of the wild type .
90458428205>Mutations in the <n>alpha and sigma-70 subunits of RNA polymerase</n> affect expression of the <n>mer operon</n> .
49769882871>Heterogeneity of <n>human serum albumin</n> .
15877632177>Total body irradiation was delivered according to a hyperfractionated scheme of 12 fractions given three per day 5 hr apart for 4 days .
76918372489>This 300 bp 5'-upstream sequence of <n>K3 keratin gene</n> , which can function in vitro as a keratinocyte-specific promoter , contains two clusters of partially overlapping motifs , one with an <n>NFkB</n> consensus sequence and another with a GC box .
59017785812>The effect of feeding patterns on fat deposition in mice .
14298368130>A mutant form of <n>Vps1p</n> lacking the entire GTP-binding domain interfered with vacuolar protein sorting in wild-type cells .
80149198010>Both proprioceptive and electroreceptive units showed a progression of receptive fields from anterior to posterior body in the rostral to caudal direction along the length of DGR .
11368911740>Molecular identification of <n>smg-4</n> , required for mRNA surveillance in C . elegans .
105800711592>Of these patients , 46 , 164 were placed on a waiting list for transplantation , 23 , 275 of whom received a first cadaveric transplant between 1991 and 1997 .
76312671030>Radiotherapy and early orchiectomy in stage D1 prostatic carcinoma .
100943143354>Interestingly , the RNA sequences selected by the mutated <n>zinc knuckle 9G8 variant</n> are efficiently recognized by <n>SRp20</n> , in agreement with the fact that the RBD of <n>9G8</n> and <n>SRp20</n> are similar .
86258067968><n>Krox-20</n> , a zinc finger gene , has a highly conserved pattern of expression in <n>r3</n> and <n>r5</n> and is functionally required for their maintenance in mouse embryos .
81147452566>These results illustrate an important role for <n>La</n> in RNA production by demonstrating its ability to clear the termination sites of <n>class III templates</n> , thereby promoting efficient use of transcription complexes by <n>pol III</n> .
2689439213>The cytosolic <n>glutathione S-transferases</n> ( <n>GSTs</n> , EC 2 . 5 . 1 . 18 ) are a superfamily of dimeric isoenzymes which catalyze the conjugation of electrophilic substrates with glutathione .
10701534514>The patient had developed left-sided low-frequency tremor and hemidystonia after a severe head trauma sustained at 15 years of age .
87338818989>Full thyroid function testing was performed on 600 randomly selected samples with normal <n>TSH</n> values and also on subjects with abnormal <n>TSH</n> levels .
88399118817>17 . 5% of cycles ) .
95287844184>The <n>mei4+ gene</n> of the fission yeast Schizosaccharomyces pombe was cloned by functional complementation .
7680629864>Molecular cloning and characterization of two <n>genes encoding gp138</n> , a cell surface glycoprotein involved in the sexual cell fusion of Dictyostelium discoideum .
79568697942>Routinely collected , processed and stored breast cancer tissue blocks recovered from the archives of the Pathology laboratory in Dar es Salaam after storage of up to 3 years were analysed by a flow cytometry for DNA ploidy and S-phase fraction .
69752066764>The daily administration of betamethasone for three weeks markedly reduced the absorption of calcium and phosphate as well as the growth rate .
63166236107>Overall prevalences of antibody were 70 per cent in cattle , 67 per cent in sheep and 76 per cent in goats as assessed by an immunodiffusion test .
18101542420>So far 15 children have been studied .
95519726524>Fluorescence in situ hybridization of metaphase spreads of chromosome 8 , containing hybrid cell line 706-B6 clone 17 ( CL-17 ) with cosmid c101F1 , placed the <n>9804 gene</n> close to the telomere at 8q24 . 3 .
36277204435>Typical and atypical clinical features of this lacrimal sac cyst are emphasized .
75283259111>Recent studies have demonstrated that the activated <n>GH receptor</n> can stimulate <n>Stat1</n> , a cytoplasmic transcription factor that becomes tyrosine phosphorylated and translocates to the nucleus , where it can interact with specific DNA sequences to modulate gene expression .
29858205782>Different sequence elements of both the retroviral vectors and the <n>c-myc gene</n> recombined during genesis of highly oncogenic retroviruses CMII , MC29 , or MH2 .
91691273418>The close proximity of the two <n>neuropeptide Y receptor genes</n> suggests that they have evolved from a gene duplication event with the small intron interrupting the coding sequence of the <n>y1 gene</n> being converted into a functional sequence within the <n>y5 gene</n> , while the reverse complementary sequence was utilized as an alternatively spliced 5' exon for the <n>y1 gene</n> .
61634332935>Effect of 2- ( p-chlorophenyl ) cyclopropylamine on 5-hydroxyindole concentration and <n>monoamine oxidase</n> activity in rat brain .
99717769477>Mutations affecting only <n>CD4</n> regulation mapped to residues previously shown to mediate the binding of <n>Nef</n> to this receptor , such as W57 and L58 , as well as to an <n>AP-recruiting dileucine motif</n> and to an acidic dipeptide in the C-terminal region of the protein .
21185194551>Furthermore , we notice two potential consensus motifs which are also found in corresponding positions in the genes for the <n>nerve growth factor receptor</n> and the <n>68-kDa neurofilament protein</n> .
7374227214>Pathogens ( Staphylococcus aureus or Gram-negative bacilli ) were isolated from only one member of staff in small numbers and irregularly and rarely in large numbers from patients .
94180403043><n>Mg-chelatase</n> of tobacco : identification of a <n>Chl D cDNA sequence</n> encoding a third subunit , analysis of the interaction of the three subunits with the yeast two-hybrid system , and reconstitution of the enzyme activity by co-expression of <n>recombinant CHL D</n> , <n>CHL H</n> and <n>CHL I</n> .
27568783455>The nature of the process formed by the successive occurrences of this arrhythmia was studied in 8 patients with a history of symptomatic paroxysmal AF .
15295306137>Interferon-alpha-induced gene expression : evidence for a selective effect of ouabain on activation of the <n>ISGF3 transcription complex</n> .
15458069528>Molecular and genetic analysis of the <n>yeast early meiotic recombination genes REC102</n> and <n>REC107 / MER2</n> .
32822323746>Antibodies made against fusion protein produced by the <n>DP1A</n> clone reacted specifically with <n>DP-I and -II</n> on immunoblots .
89890258943>When voltage-operated Ca2+ channels ( VOC ) were blocked by nifedipine , midazolam , in concentrations more than 1 microM , attenuated both phasic and tonic responses .
83317289141>Binding of <n>U2 small nuclear ribonucleoprotein</n> was partially inhibited .
9617119586>Hematology problem of the month : band or seg ?
8654390261><n>Heme oxygenase 1</n> is an essential enzyme in heme catabolism that cleaves heme to form biliverdin , iron , and carbon monoxide .
2780157407>The characteristic feature of liver and spleen MP function in patients with VHA associated with <n>HBsAg</n> carriership consisted in the lack of the compensatory reaction on the part of spleen MP , which was likely to be connected with overstrain of long standing and depletion of the MP system due to permanent antigenic stimulation of <n>HBsAg</n> .
109038374960>Since the <n>RINX gene</n> is likely an ortholog of the <n>goldfish Vsx1 gene</n> , it has been named <n>VSX1</n> by the Human Gene Nomenclature Committee .
63085366091>The <n>hepatitis A virus antibody</n> ( <n>anti-HAV</n> ) in chronic diffuse liver diseases .
11024300217>Nature 398 , 828-830 ) that the amino acid sequences of peptide fragments obtained from a polypeptide found in a complex of proteins that alters chromatin structure ( <n>ARC</n> ) are identical to portions of the deduced open reading frame of <n>TIG-1 mRNA</n> .
30145933250>Diazepam ( 3 mg / kg ) generalized to Ro 11-6896 whereas the structurally related Ro 5-4864 ( 3 mg / kg and 30 mg / kg ) did not .
113740511213>Additional factors such as advanced age , concomitant use of corticosteroids or anticoagulants , prior ulcer complications and co-morbid diseases may further increase the risk of bleeding .
12953734585>The magnitude of the early response was 241 + / - 51% in A ( % baseline RL ; mean + / - SE ) , and significantly less in B ( 119 + / - 7% ) and C ( 131 + / - 16% ) ( p < 0 . 01 ) .
14082192023>In the eight patients with persistent generalized lymph-adenopathy ( PGL ) and nontender , nonenlarging nodes , pathologic analysis revealed lymphoid hyperplasia .
25432263186>We conclude that ( a ) the likelihood of detecting carcinoma or atypical hyperplasia exclusively in the adipose tissue component of grossly benign breast biopsies is extremely low , and ( b ) a possible cost-effective method of sampling grossly benign breast biopsies consists of initially submitting a maximum of 10 blocks of fibrous parenchyma for each case , then examining the remaining tissue histologically only if carcinoma or atypical hyperplasia is found among these blocks .
10400712811>Simian parainfluenza virus 5 ( SV5 ) is a prototype of the Paramyxoviridae family of nonsegmented negative-sense RNA viruses .
112712973645>Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients .
118582561744>Despite considerable research , an explanation of this effect has been elusive .
20547545591>The standard principles of surgical management must be adhered to when using Sandostatin to treat patients with these disorders .
47597224993>Polycythemia-1973 .
110141973280>From two inhibitor scaffolds , we have identified potent and selective inhibitors for sensitized <n>kinases</n> from five distinct subfamilies .
112098141885>The purpose of this investigation was to study the morphological characteristics of the fibrous tissue capsule resulting from the implantation of aluminum calcium phosphate ( ALCAP ) and hydroxyapetite ( HA ) bioceramics .
18517567462>Biol .
107609505991>A distinct staining pattern for the <n>N-utrophin</n> was not detectable , although it was expected to localise at the <n>actin</n> stress fibers .
17797696147>The sequence of the repressor locus , c , of the Streptomyces temperate phage , phi C31 , was shown previously to contain an open reading frame encoding a 74 kDa protein .
66481566380>Introductory remarks .
93829247020>Accumulated evidence indicates that , upon stimulation with <n>interferon-gamma</n> ( <n>IFN-gamma</n> ) , three beta-type subunits , designated <n>LMP2</n> , <n>LMP7</n> , and <n>PSMB10</n> , are incorporated into the <n>20S proteasome</n> by displacing the housekeeping beta-type subunits designated <n>PSMB6</n> , <n>PSMB5</n> , and <n>PSMB7</n> , respectively .
90651709015>The addition of zidovudine did not influence this transfer .
96584052911>The <n>Dax-1 gene</n> encodes a protein that is structurally related to members of the <n>orphan nuclear receptor superfamily</n> .
107042854976><n>Human AP-2rep</n> repressed both reporter expression from a transiently transfected <n>AP-2alpha promoter</n> and the endogenous <n>AP-2alpha gene</n> and inversely was negatively regulated by <n>AP-2alpha</n> .
113524238274>The radial forearm flap is used most commonly , however the lateral arm flap may be the flap of choice in certain situations .
82620544261>Similarly , the N-terminal cytoplasmic domain of the <n>latent membrane protein 2A</n> ( <n>LMP2A</n> ) of the Epstein-Barr virus ( EBV ) contains a single copy of the <n>Tyr-X-X-Leu / Ile-containing motif</n> which could play a critical role in B cell transformation .
110350373288>The N-terminal small segment of <n>yeast TAF145</n> ( <n>yTAF145</n> ) binds to <n>TBP</n> and thereby inhibits <n>TBP</n> function .
110597863590><n>VEGF promoter</n> activity in transient transfections was decreased by either pharmacological or genetic inhibition of <n>EGFR</n> , <n>Ras</n> , or <n>phosphatidylinositol 3'-kinase [</n>1 <n>PI</n>1 <n>(</n>1 <n>3</n>1 <n>)</n>1 <n>kinase</n>1 <n>]</n>1 .
108728314898>A murine expressed sequence tag ( EST ) showing homology with <n>erythropoietin receptor</n> ( <n>EPOR</n> ) was identified in the EST database .
98281378390>The <n>Schizosaccharomyces pombe rad1+ cell cycle checkpoint control gene</n> is required for S-phase and G2 / M arrest in response to both DNA damage and incomplete DNA replication .
27460993437>The mobility of the upper and lower premolars under load was investigated in relation to the interproximal contact and occlusal facets .
80357968485>32Pi labeling or isoelectric focusing analysis of <n>eIF-2 alpha</n> from conditional <n>casein kinase II mutants</n> indicated that phosphorylation of <n>eIF-2 alpha</n> is abolished or dephosphorylated forms of <n>eIF-2 alpha</n> are detected when these strains are grown at the restrictive growth conditions .
90381669008>Exons A1a and A1b are separated from each other by a 124-nucleotide intron .
17340205425>Immunostaining of cells transfected with these constructs revealed that both the myristoylated and nonmyristoylated mutants were localized in nuclei , whereas <n>wild-type PKC alpha</n> was primarily cytoplasmic and perinuclear .
23269469245><n>Plasma lecithin / cholesterol acyltransferase</n> ( <n>LCAT</n> ) activity in multiple-organ donors : a predictor of allograft viability in clinical liver transplantation .
93901831948>Western blot analysis of various bovine tissues with human <n>NMT peptide antibody</n> indicated a common prominent immunoreactive band with an apparent molecular mass of 48 . 5-50 kDa in all tissues .
20216306109>These differences involve specific hydrogen-bonding interactions between the protein and DNA , including guanine N7 sites in the major groove of DNA , and alterations in DNA phosphodiester conformation induced by protein binding .
13213324629>Transient transfection assays showed that site A is necessary and sufficient for <n>RXR</n> alpha-mediated transactivation of the <n>apoAI gene basal promoter</n> in human hepatoma HepG2 cells in the presence of RA and that this transactivation is abolished by increasing amounts of cotransfected <n>ARP-1</n> .
94907276246>This structure interconnects specific triplets of the basal bodies with the microtubular bundles that emerge from the basal apparatus .
88927552618>When this DNA fragment was placed upstream of the <n>chloramphenicol acetyltransferase</n> ( <n>CAT</n> ) reporter gene and transfected into a carp CF cell line , it could drive the synthesis of <n>CAT enzyme</n> 16 times more efficiently than the promoterless <n>pCAT-Basic</n> .
1909960109>A single i . p . injection of d , l-baclofen 10 mg / kg both reduced noradrenaline ( NA ) biosynthesis in vivo ( 31% ) and the endogenous concentration of normetanephrine ( NMN ) ( 32% ) and increased NA levels ( 28% ) .
99597379209>The case for neutrinos from SN 1987A .
98784375648>The active site includes the acidic triad Asp53 ( the site of phosphorylation ) , Asp10 and Glu9 .
94318288844>Furthermore the median increase in cyclosporine DR / C ( SS trough ) was 18 l h-1 ( -3 . 1 to 42 . 1 l h-1 , interquartile range ) .
106254946046>These results show that the CAAT-region is involved in upregulating the <n>MDR1 promoter</n> in HL60 / VCR cells .
96363582709>The virus-associated VAI RNA of adenovirus is a small highly structured RNA that is required for the efficient translation of cellular and viral mRNAs at late times after infection .
36457334319>Hyperthyroidism .
109185723701>While interactions of <n>WT</n> and variant <n>TGF-alpha</n> with the <n>ErbBs</n> all result in <n>ErbB2</n> activation , they produce different biological consequences , suggesting that the various <n>TGF-alpha precursors</n> differentially modulate <n>ErbB</n> signaling .
279678988>By contrast , <n>secretory HI antibodies</n> were not demonstrated at the onset of illness in any of the patients , but their formation started early and the antibodies reached maximal levels about 10 days after onset of illness .
80133489487><n>Mammalian ABPs</n> and <n>SHBGs</n> bind sex steroids with high affinity , but some binding properties differ among species .
1727488699><n>PRDII-BF1-derived cDNAs</n> did not result in stimulation of either basal or tat-induced activated gene expression .
83550635728>The rCBF ratio was mainly reduced in frontal lobes ( 65% ) .
92120634438>We isolated several overlapping A-phage and cosmid clones that cover more than 100 kb of human DNA and contained the entire <n>VDR gene</n> .
13942002904>The treatment group also showed in vivo T-cell activation with an initial lymphopenia followed by a rebound lymphocytosis and upregulation of the subset markers <n>CD25</n> ( <n>interleukin 2 receptor</n> ) and <n>CD45RO</n> ( T-memory cells ) .
91568831408>Selected parameters : heart rate ( HR ) , arterial blood pressure ( ABP ) and arterial O2 saturation ( SaO2 ) monitored by pulsoximetry were measured during the procedure .
9710599968>Persistent activation of <n>mitogen-activated protein kinases p42</n> and <n>p44</n> and <n>ets-2</n> phosphorylation in response to <n>colony-stimulating factor 1 / c-fms</n> signaling .
109986791656>The psychologic factors associated wth serious illness , terminal prognoses , and dying complicate the scenario even more as compared with that of nonmalignant pain .
18320192431>It is transparent , cheap to be made , and easy to empty and was tested in 118 animals for two and four weeks .
22768911531><n>Coenzyme Q10</n> : blood levels and metabolic demand .
28838711120>A drug with ISA "down regulates" <n>beta receptors</n> ; thus , when the drug is withdrawn there is no post-beta-blocking drug hypersensitivity in contrast to agents without ISA .
90365291166>The workup included skin tests ( up to 1 microgram / ml , Pharmacia ) , measurement of specific serum <n>IgE</n> with RAST-CAP ( Pharmacia ) , and CAST with three concentrations of bee ( Apis mellifera ) and wasp ( Vespula spec . ) venom ( Aquagen ALK ) .
13244044425>A position-independent activation domain which contained conserved regions II and III was identified at the carboxyl terminus of the <n>HNF-3 beta protein</n> ( amino acids 361 to 458 ) .
110079616257>Mutations in genes encoding <n>PR65 / A subunits</n> have been identified in several different human cancers and the <n>PP2A</n> inhibitor , termed fostriecin , is being tested as an anticancer drug .
92941617947>In contrast to the wild-type protein , expression of <n>p45 NF-E2</n> lacking this activation domain in an <n>NF-E2</n> null cell line fails to support enhancer-dependent transcription in transient assays .
69724436757>Similar clinical evaluation of an obligate carrier revealed no ocular abnormalities .
18121025714>The present study reports visual evoked potential responses to pattern reversal ( VEP-P ) in ten third trimester pregnant women and changes in latency of NPN complex when compared with these responses in the non pregnant state .
109729901323>Abrogation of <n>p53</n> function by <n>E6</n> resulted in an increase in the spontaneous mutation frequencies at the heterozygous <n>thymidine kinase</n> ( <n>TK</n> ) locus but not at the hemizygous <n>hypoxanthine phosphoribosyl transferase</n> ( <n>HPRT</n> ) locus .
40246854771>55 + / - 11% ) , all other parameters showed a significant increase : RS index 5 . 4 + / - 1 . 4 mVolt to 6 . 0 + / - 1 . 7 mVolt ( p less than 0 . 01 ) ; EDD 6 . 3 + / - 0 . 7 to 6 . 8 + / - 0 . 9 cm ( p less than 0 . 001 ) ; HV 1017 + / - 151 ml to 1099 + / - 261 ml ( p less than 0 . 01 ) ; EDV 371 + / - 131 ml to 441 + / - 175 ml ( p less than 0 . 001 ) ; RBV 117 + / - 57 ml to 151 + / - 77 ml ( p less than 0 . 001 ) .
67116426475>Significant immunoglobulinuria developed prior to the development of azotemia , significantly decreased creatinine clearance , significant proteinuria ( greater than or equal to 3+ dipstick or greater than or equal to 5 gm per 24-hour urine collection ) , or oliguria .
88730635428>ECM disruption in Lytechinus embryos caused a relative drop in <n>USF RNA</n> accumulation levels to approximately 60% of control embryos , while <n>LpS1 RNA</n> accumulation levels dropped to less than 5% .
6197822027>Deep tans were induced over the backs of volunteers with repeated exposure to longwave ultraviolet radiation ( UV-A ) .
68017786572>Significance of the pulmonary gas exchange reaction to physical loading in evaluating the effectiveness of mitral commissurotomy .
118106851678>It is shown that the displacement distribution measured by q-space MRI in both the large displacement ( i . e . , large r ) and the long-wavelength ( i . e . , small q ) limits is the same 3D Gaussian displacement distribution assumed in DT-MRI .
820723242>Electrophoretic mobility shift analysis indicates that <n>NF-IL-6</n> , as well as other related members of this family , bind specifically to the <n>NF-IL-6</n> site in the <n>IL-8 promoter</n> .
79842619927>The ICBF in the ischaemic cortex revealed a graded reduction from the ischaemic centre to the surrounding tissues .
36599949819>These changes at the site of injection consist of a focal abnormality characterized by a slight increase in signal intensity on T1 weighted images and markedly increased signal intensity on T2 weighted images .
68359146626>Copper treatments were assigned to simulate the different levels of copper intake that might result from differences in daily feed intake similar to the practice followed with commercial industry .
56894275650>3- ( N-Alkyl-N-2-chloroethylaminomethyl ) -5- or 7-halogenobenzo [ b ] thiophen hydrochlorides .
94758989437>Transcervical amnioinfusion .
117616012163>A computer program , ACCESS-IAQ , is developed to simulate the airflow pattern , the time history of the contaminant concentrations in the occupied zone , and the inhalation exposures .
108713799832>As with <n>VP16</n> , the transactivation function of <n>Luman</n> is also regulated by <n>HCF</n> .
23258956135>Slowly adapting <n>type I mechanoreceptor</n> discharge as a function of dynamic force versus dynamic displacement of glabrous skin of raccoon and squirrel monkey hand .
32700859965>Hypomagnesemia was due to magnesium wasting by the kidney .
109083177625>Interestingly , although <n>E domains</n> of these two receptors are much less conserved , replacement of this domain in <n>rtER</n> by its human counterpart resulted in higher estradiol sensitivity but no increase in the magnitude of transactivation .
61370285956>Propranolol also effectively controlled her familial tremor .
78717213932>From sequence alignments with phylogenetically related viruses , including tymoviruses , we predicted that <n>p223</n> contained a <n>papain-like proteinase domain</n> with a putative catalytic cysteine994 and histidine1075 .
23335457024>The distribution of their <n>fibrinogen</n> levels was Gaussian , but more wide-based than the distribution of our normal controls .
78947615791>The aim of this retrospective study was to demonstrate that in certain cases of expulsive choroidal hemorrhage ( ECH ) anatomical success and useful vision can be obtained with repeated vitreoretinal surgery .
15415772231>17 volunteer deaf Ss were compared with 18 volunteer hearing Ss on the Stanford Hypnotic Clinical Scale ( SHCS ) of Morgan and J .
6199489579>1 The effects in normal subjects of a single oral dose of Motival ( one tablet , containing fluphenazine 0 . 5 mg and nortriptyline 10 mg ) on the contingent negative variation ( CNV ) , reaction time , heart rate , blood pressure and self-rating scales for alertness , anxiety , tension , detachment and depression were compared with those of diazepam ( 5 mg and 7 . 5 mg ) and placebo or propranolol ( 60 mg ) .
21570675149>Summers , Virology 89 : 517-527 , 1978 ) .
67951196562><n>Lens aldose reductase</n> in diabetic and galactosemic cataracts .
15519109711>This DNA motif represents a novel protein-binding sequence .
16448143565>The virus encodes a 40-kDa protein , <n>tax</n> , that is important for the immortalization of T cells .
82267949681><n>[ Ala85 ] Dk ( 69-85 )</n> retains full biological activity .
7594007494>Platelet serotonin ( 5-HT ) and <n>5-HT releasing factor</n> in plasma of migrainous patients .
95019828075>CONCLUSIONS : <n>XCoe2</n> may play a pivotal role in the transcriptional cascade that specifies primary neurons in Xenopus embryos : by maintaining Delta-Notch signalling , <n>XCoe2</n> stabilises the higher neural potential of selected progenitor cells that express <n>X-ngnr-1</n> , ensuring the transition between neural competence and irreversible commitment to a neural fate ; and it promotes neuronal differentiation by activating <n>XNeuroD</n> expression , directly or indirectly .
72403431976>Strontium-90 was inject i . v . into pregnant rats on day 18 post conception ( p . c . ) .
55332145584>Iodine metabolism in chronic thyroiditis .
100901256167>However , with the alpha1 antagonist prazosin ( 5 x 10 ( -8 ) -5 x 10 ( -7 ) M ) , no relaxation occurred .
11580941919>RESULTS : At latest examination , mean UPDRS II and III scores had improved by 30% ( on stimulation , off therapy ) with mean 50% reduction in daily off time .
96178074680>A phylogenetic analysis of the <n>reverse transcriptase domain</n> confirms our differential genetic assessment that <n>Cyclops</n> from pea is a novel element with no specific relationship to the previously described <n>Gypsy-like elements</n> from plants .
9545353283>Instead , it contained two tandem <n>kappaB elements</n> and a variant <n>activating transcription factor / cAMP response element</n> site , which closely resembled sites in the <n>E-selectin gene</n> that are required for TNF-alpha- or LPS-inducible expression .
11112438560>Copyright 2000 Academic Press .
95242731523>This paper describes the genomic organization of mouse <n>gC1qBP</n> and the characterization of its 5' flanking region .
81966181145><n>PRL-1</n> is able to dephosphorylate phosphotyrosine substrates , and mutation of the active-site cysteine residue abolishes this activity .
98171316467>A Chinese ( HK ) SF-36 survey form was developed by an iterative translation process .
19034042530>Infarct regional ejection fraction improved by 10 . 1 + / - 2 . 1% between early and late studies when the infarct-related artery was patent and by 4 . 8 + / - 1 . 4% if it was occluded ( p = 0 . 048 ) ; changes in global and noninfarct regional ejection fraction were similar irrespective of perfusion status .
97739815410>The activated <n>glucocorticoid receptor</n> forms a complex with <n>Stat5</n> and enhances Stat5-mediated transcriptional induction .
113827011224>This partial transection could permit <n>vasopressin</n> to be secreted in response to a larger rise in plasma sodium concentration .
96882648203>This repressor is however unlikely to mediate <n>spi 2 . 3 3' UTR silencer</n> action since it was not detected in rat hepatocytes .
14670882082>Abstracts .
113879401250>The severity of pathologic changes increased with the magnitude of percussion .
97437209722>ANIMALS : Fifty dogs with naturally developing DM .
80498858041>Acute pancreatitis : a multisystem disease .
93120287987>Interestingly , the <n>RXRalphaF318A</n> constitutive activity generated within heterodimers in the presence of BMS614 requires the integrity of both <n>RXR</n> and <n>RAR AF-2</n>1 <n>domains</n>1 .
17706512371>Fundamental and clinical evaluation of equilibrium dialysis--radioimmunoassay system for measurement of serum free thyroxine .
102160522507>The aims of this study were to determine and rank the frequency of self reported visual disability in daily tasks performed by glaucoma patients ; to examine the interrelation between disabilities using factor analysis ; to study the relation between perceived visual difficulty and a measure of the severity of visual field loss ; to develop a glaucoma specific subgroup of questions ; and examine the validity and reliability of this subgroup of questions .
84132097709>The amino-terminal third of the protein contains a <n>high-mobility-group motif</n> characteristic of DNA-binding proteins .
9030688151>In <n>rlf2 mutants</n> , telomeric chromatin is perturbed : Telomeric silencing is reduced and <n>Rap1p</n> localization is altered .
102181094027>Solution structure and mechanism of the <n>MutT pyrophosphohydrolase</n> .
95565617773>Among the <n>H / ACA snoRNAs</n> associated with <n>Gar1p</n> , one can distinguish a large group of <n>snoRNAs</n> that are not essential in yeast and serve as guides for pseudouridine synthesis onto the <n>pre-rRNA molecule</n> .
116003659131>Against gram-positive organisms , E-4767 and E-5065 were , in general , eight- and fourfold more active than tosufloxacin , which is the most potent of the reference compounds .
39284426391>A significant degree of homology was also found among these genes and the <n>Mtase gene</n> of related phage SPR , which codes for an enzyme with different modification specificity .
19155802986>These results suggest that NZ-107 may be a useful drug for the treatment of bronchial asthma by reducing late-phase airway responses and airway hyperreactivity .
96275986409>RESULTS : Of the patients with IS , 67% had significantly greater values of directional preponderance on the OVAR test ( a measure of otolith system imbalance ) compared with control subjects .
113906504033>Additional deletion mutations revealed a new , 67-amino-acid functional domain within the proline-rich region of <n>SLP-76</n> , which we have termed the <n>P-1 domain</n> .
21293382919>The deduced amino acid sequence has the greatest homology ( 61% ) to the <n>green alga Scenedemus obliquus plastocyanin</n> .
86053248123>The viral LTR was used as the promoter .
29236873632>We also examined the relationship between the side of sinusitis and the cleft side in patients with unilateral cleft palate .
85225306995>When <n>nifA mRNA</n> 5' start points were mapped by primer extension , both a minor upstream transcript ( s ) starting 45 bp distal to the anaerobox and a major downstream transcript starting 10 bp distal to the <n>sigma 54</n> box were observed .
78221612456>The sequence of <n>monkey opsin</n> closely resembles the human sequence at the nucleotide and the amino acid levels , with the latter having only 7 differences out of 348 residues .
87632078754>It is the oxidation peak of this product , arising in acidic media at 0 . 42 V , which was analysed using DPV , again following the accumulation of clenbuterol at the Nafion-modified CPE .
9227799928>Its potential as a diagnostic tool for epidemiological surveillance was assessed in comparison with three other diagnostic tests : stool examination , ELISA with <n>soluble egg antigen</n> ( <n>SEA</n> ) and the circumoval precipitin test ( COPT ) .
105422498467><n>Albumin</n> expression is maintained in the liver by a combination of liver-enriched transcription factors such as <n>CAAT enhancer-binding protein ( C / EBP ) alpha</n> and <n>C / EBPbeta</n> .
83068349938>T2 cancers should not be excluded from the benefit of preoperative irradiation .
30730914232>Amounts of glucose infused during the last 20 min of each 2 hour <n>insulin</n> infusion were ( at 1 and 10 m / kg / min respectively ) : before treatment ( K+ = 2 . 7 mmol / l ) : 2 . 4 and 8 . 4 mg / kg / min ; after spironolactone ( K+ = 3 . 9 mmol / l ) : 3 . 3 and 15 . 4 mg / kg / min ; after indomethacine ( K+ = 3 . 7 mmol / l ) : 5 and 19 mg / kg / min after stopping drugs ( K+ = 2 . 9 mmol / l ) : 2 . 5 and 5 . 3 mg / kg / min .
98927366450>A gapped search with the C-terminal region of <n>CDED / LIOR</n> revealed a 36-41% similarity to several proteins related to signal transduction and cell replication , such as <n>ORC1</n> and <n>KSR</n> .
90714076496>Circulating <n>oxytocin</n> in male guinea pigs affected by the female cohabitation and reproductive condition .
112329472652>Prophylactic lymph node dissection or radiation therapy to the nodal chain may decrease local recurrence but does not consistently affect overall survival .
84999169851>The <n>COL7A1 gene</n> , which encodes <n>type VII collagen</n> , has been implicated as a candidate gene for dominantly and recessively inherited forms of dystrophic epidermolysis bullosa .
94202206479>Cell factor-mediated regulatory interactions are involved in regulating the restricted expression of the <n>HCMV major immediate-early ( IE ) gene</n> ( J .
112374912414>AIMS : To establish a baseline and intraindividual fluctuations of the tumour markers <n>CEA</n> , <n>CA 50</n> and <n>CA 242</n> in patients cured from colorectal cancer , and to test the hypothesis that serum concentrations and intraindividual fluctuations do not differ from the concentrations in cancer-free individuals .
17345704253>Effects of <n>thromboxane synthetase</n> inhibition on postburn mesenteric vascular resistance and the rate of bacterial translocation in a chronic porcine model .
41232174806>Formation of hyphae and chlamydospores by Cryptococcus laurentii .
75185783492>The transforming protein of Rous sarcoma virus , <n>pp60v-src</n> , and its normal cellular homolog , <n>pp60c-src</n> , differ not only in oncogenic potential but also in their subcellular localization and cytoskeletal binding ability . <n>pp60v-src</n> has been shown to stably associate with a detergent-insoluble cytoskeletal matrix , whereas <n>pp60c-src</n> does not .
19963121739>DNA from PCR was labeled and used to isolate several lambda gt11 cDNA clones , including one full-length one ( <n>Dd kinase-2</n> ) .
105422776587>The <n>importin alpha . beta heterodimer</n> mediates nuclear import of proteins containing classical nuclear localization signals .
72969972804>Nineteen patients with non-visualized gallbladder with OCG subsequently had Tc-99m-PyG cholescintigraphy performed .
118673881758>The EC ( 50 ) for suppression of long-term memory ( the concentration decreasing memory by 50% ) of fear conditioning to context was 2 . 00% plus / minus 0 . 01% ( mean plus / minus SEM ) , and for fear conditioning to tone was 3 . 45% plus / minus 0 . 26% , ( P < 0 . 05 ) .
10527106362>OBJECTIVE : Although the preponderance of findings offer support for transient ( where is it ? ) as opposed to sustained ( what is it ? ) deficit , a need remains for specific depiction of the deficit .
16967158614>E .
78345823884>Dietary supplement with fish oil and related n-3 EFAs has been used to study their antihypertensive property in animals and humans with borderline and essential hypertension .
75114444912>HCV infection acquired during or after BMT caused only mild acute hepatitis C , which progressed to chronic hepatitis C in one patient surviving 10 years after BMT .
79141926299>Gel-shift assays with nuclear extracts and oligonucleotide sequences spanning the 0 . 125-kb promoter region detected an ETS-immunoreactive complex , present most abundantly in cells overexpressing <n>HER2</n> , whose high-affinity binding depended on the <n>GAGGAA response element</n> .
30388913588>Northern analyses of RNAs from mouse tissues and cell lines indicated that <n>p11 mRNA</n> levels vary widely .
110281318175>Further research is required to better measure treatment effects , modification of MS natural history , and net societal costs of <n>IFN beta-1b</n> in RRMS .
17767152385>If delay has occurred between centrifugation and the measurement , causing substantial loss of CO2 , equilibration of the sample with a gas mixture corresponding to PCO2 = 5 . 3 kPa prior to the measurement is recommended .
89150518873>Magnetic resonance imaging in coccidioidal arthritis .
68055046146>For steers the urinary N values were 403 and 295 mg / kg W0 . 75 at 200 and 350 kg live weight respectively and total N excretion including faecal N was 408 and 320 mg / kg W0 . 75 .
7743697635>Data from the V-HeFT II show that at 2-year follow-up , a progressive rise of plasma norepinephrine was observed in both treatment arms , suggesting that disease progresses despite treatment with either an <n>angiotensin-converting enzyme</n> inhibitor , enalapril , or vasodilator therapy with hydralazine / isosorbide dinitrate .
91714689119>Diver respiratory responses to a tunable closed-circuit breathing apparatus .
108486051115>Phosphorylation of tyrosine residues in the <n>kinase domain</n> and juxtamembrane region regulates the biological and catalytic activities of <n>Eph receptors</n> .
32788293965>The indications for its use include every primary and secondary rhinoplasty candidate unless tip grafts are going to be under tension or if the deformity is minor .
6968588514>The effect of pure natural <n>porcine secretin</n> on endocrine and exocrine pancreatic secretion was studied in the totally isolated perfused porcine pancreas .
15048535035>Exogenous <n>LHRH</n> is also known to facilitate mating behavior in several species .
90539739010>CONCLUSION : Chronic administration of misoprostol may have caused a negative natriuretic effect in cirrhotic patients with ascites .
14266357312>The in vivo profile of <n>ZFH-2</n> in the larval CNS shows intriguing overlap with <n>DDC</n> in specific serotonin and dopamine neurons .
80052303919>Using this reporter gene system , we previously showed that EPO-induced activation of the <n>c-fos promoter</n> can be detected rapidly and sensitively as an elevation of <n>cellular luciferase</n> activity .
12372061875>Demonstration of the agent was performed from the 6th to the 11th day p . i . by direct microscopic methods ( Stamp and auramine staining , fluorescent antibody technique ) ; the Coxiella content was determined by titration in embryonated hen's eggs .
97993621189>These characteristic structural features were used to create the abbreviation <n>AZF1</n> ( <n>Asparagine-rich Zinc Finger protein</n> ) .
99641719961>NMR of diffusing atoms in a periodic porous medium in the presence of a nonuniform magnetic field .
110281311172>Cost-effectiveness of <n>interferon beta-1b</n> in slowing multiple sclerosis disability progression .
84716298637>Pseudosubstrate ( 19-36 ) , derived from the C-terminus of <n>Ca-dependent PKC isotypes</n> , inhibited <n>beta-PKC</n> but not <n>nPKC</n> activity using either <n>Histone IIIS</n> or peptide ( 19-31 ) as substrate .
77716717740>Sensing with chemically and biologically modified carbon electrodes .
80864534142>Structure , promoter analysis and chromosomal assignment of the <n>human APEX gene</n> .
106407346015>Upon tyrosine phosphorylation at the ITIMs , these molecules recruit <n>SH2</n> domain-containing <n>phosphatases</n> such as SH2-containing <n>tyrosine phosphatase-1</n> and negatively regulate cell activity .
87092517743>Homologous recombination between the Autographa californica nuclear polyhedrosis virus ( AcNPV ) genome and a 0 . 6-kbp-long DNA fragment derived from the putative <n>DNA helicase gene of Bombyx mori nuclear polyhedrosis virus</n> generates eh2-AcNPV , an expanded-host-range AcNPV mutant ( S .
104056359896>The transcriptional activities of the full-length promoter ( -295 to +85 ) and of three deletion constructs ( -197 , -154 and -74 to +85 ) were significantly down-regulated in resistant cells .
95235516445>Both variants display the seven-transmembrane topology that is typical for <n>G protein-coupled receptors</n> .
91648561843>This region does not contain an identifiable TATA element , indicating that transcription of the <n>glutaminase gene</n> is driven by a TATA-less promoter .
108334868437>Age > / = 50 years ( odds ratio [ OR ] , 14 . 1 ) , BMI > / = 28 kg / m ( 2 ) ( OR , 5 . 7 ) , triglycerides > / = 1 . 7 mmol / L ( OR , 5 ) , and <n>alanine aminotransferase</n> ( <n>ALT</n> ) > / = 2N ( OR , 4 . 6 ) were independently associated with septal fibrosis .
2346262998>XXI .
63282722809>They generated ca .
13808255179>Northern blot analyses demonstrate that 3 . 9- and 5-kilobase mRNAs corresponding to the cDNA were present in all tissues examined , suggesting that the protein it encodes performs a housekeeping function .
20525447285>Furthermore , the <n>DNA polymerase II complex</n> was difficult to obtain from <n>dpb2-1</n> mutant cells , suggesting that a stable <n>DNA polymerase II complex</n> requires <n>DPB2</n> and is essential for chromosomal replication .
10982076815>Linking continuous community-based morbidity recording of influenza-like illness ( ILI ) with virological sampling has consistently proved its value as one of the earliest indicators of circulating influenza activity .
94547351603>Levels of the <n>MEK</n> inhibitor PD98059 that block EGF-induced mitogenesis and <n>MAP kinase</n> phosphorylation also abrogate EGF-induced focal adhesion disassembly and cell motility .
79599533016><n>IFI16</n> consists of ten exons and nine intervening introns spanning at least 28 kilobases ( kb ) of DNA .
80823609621>Smoking history and awake oxygen saturation ( SaO2 ) was recorded in all of them .
103596637090>In a heterologous transcriptional system in which the upstream regions of <n>oIFNtau</n> were inserted in front of <n>simian virus 40 ( SV40 ) promoter</n> , the regions between bases -654 and -555 were determined as being the enhancer region required for <n>oIFNtau-SV40-CAT</n> transactivation .
85999469363>The evidence presented here suggests that the <n>p40 complex</n> is a ribonucleoprotein complex containing <n>L1Hs RNA ( s )</n> and that protein-protein interactions in which alpha-helix structures participate , for example coiled-coils , may occur in the complex .
10834781640>However , the elderly group showed significantly longer mean residence times ( MRTs ) and lower plasma clearance of lidocaine during the period compared with the adult group ( P < . 05 ) .
77820879820>Two major and one minor transcription initiation sites were assigned to positions +1 and +24 and position +14 , respectively , by a combination of <n>ribonuclease</n> protection , primer extension , and 5' RACE analyses .
85384833612>Taking into consideration weight and seasonal changes in bone mass , total ( TBBMC ) and regional body bone mineral content were measured in 38 women treated with <n>GnRH</n> agonists for 6 months for endometriosis or leiomyomata .
118756957365>Time to progression was 6 months ( 5-7 months ) with a median survival from registration of 9 . 6 months ( 95% CI 8-12 months ) .
102281551147><n>SCFFWD1</n> may be critical for tumor development and suppression through regulation of <n>beta-catenin protein</n> stability .
16491733959>In addition to the previously identified and characterized <n>attenuator 1</n> situated 93 nucleotides downstream from the major late transcription start site , a second attenuator , <n>attenuator 2</n> , situated 55 nucleotides downstream from it , has been identified .
21160716641>A long follow-up study revealed that convalescent stage children still have the potency to have an immediate type hypersensitivity reaction on exposure to mite antigen , with a high titer of <n>mite specific IgE</n> in their sera , but they are free from asthmatic attacks because of the reduction in the amount of mite antigen in the body , as shown by the reduction in the amount of <n>mite specific IgG</n> .
17857492394>These changes weren't so significant in the group of obese children who didn't lose weight .
60933637990>USA 80 , 3618-3622 ) The two proteins show 36% identities in their amino acid sequence , in an alignment requiring six gaps .
75952213870>After cells were stably transfected with <n>CIITA</n> , endogenous <n>MHC class II genes</n> were constitutively expressed , and <n>MHC class II promoters</n> , delivered by transfection , were actively transcribed in CIITA-expressing cells .
18867746681>POU-specific and <n>POU-homeo domains</n> of <n>Oct3</n> were produced in Echerichia coli for characterization of DNA binding to the octamer sequence .
67546626518>Bullous angiolymphoid hyperplasia with eosinophilia .
10996934830>No title available .
107274336874>Regulation of <n>urokinase plasminogen activator gene</n> transcription in the RAW264 murine macrophage cell line by <n>macrophage colony-stimulating factor</n> ( <n>CSF-1</n> ) is dependent upon the level of cell-surface receptor .
112784611446>Polyclonal antibodies against the N-terminal part ( amino acids 12-363 ) and the C-terminal part ( amino acids 330-730 ) of <n>rainbow trout HIF-1alpha protein</n> recognized <n>rainbow trout and chinook salmon HIF-1alpha protein</n> in Western blot analysis .
92490391914>It is thus one of the key enzymes involved in the triiodothyronine-mediated control of growth , differentiation and basal metabolism in vertebrates .
10839470645>Similarly , comparison of percentage reductions of heart rate at supine , sitting and exercise by repeated measure analysis showed the Malays to have significantly higher change compared to the Chinese ( p = 0 . 040 ) .
8917696857>To analyze the mechanism of <n>fos / jun</n> activation by TCDD we have used electrophoretic mobility shift and transient expression assays of reporter gene constructs containing response elements for 12-O-tetradecanoyl-phorbol-13-acetate ( <n>TRE</n> ) , serum ( <n>SRE</n> ) , cAMP ( <n>CRE</n> ) , and aromatic hydrocarbons ( AhRE ) from the <n>fos</n> and <n>jun genes</n> fused to the <n>firefly luciferase gene</n> under the control of the <n>SV40 minimal promoter</n> .
10411160270>The mysteries of geographic variability in nonmelanoma skin cancer incidence .
86172374852>The two different phosphoforms of <n>STAT5</n> have identical in vitro DNA binding specificity and reactivity with tyrosine phosphopeptides , but differ in their cellular localization .
4138546395>Changes in tissue PCO2 were less dramatic and did not vary significantly from those recorded in venous blood .
97348089714>To improve test efficiency , we modified our previously introduced contrast / color card test by including a patterned test stimulus and reducing the number of stimuli in both experimental phases .
77474622868>Sequence comparisons of <n>prokaryotic RCR initiators</n> has revealed a set of three common motifs , two of which , a putative metal coordination site and a downstream active-site tyrosine motif , could be tentatively identified in <n>parvoviral replicator proteins</n> .
94007386499>An even greater inflammatory response was observed after intratracheal instillation of ufCB , but not after CB instillation .
111339275165>Validity of NIR spectroscopy for quantitatively measuring muscle oxidative metabolic rate in exercise .
110831542689>Ten males performed both test conditions and oxygen uptake VO2 , heart rate , minute ventilation VE , perceived exertion and spinal shrinkage were recorded .
13330538682>A major mechanism whereby <n>steroid hydroxylase gene</n> transcription is regulated in the adrenal cortex requires the pituitary peptide hormone , <n>ACTH</n> , which acts via cAMP .
11777632229><n>AF</n> showed a mixed nuclear / cytoplasmic pattern of expression in the epithelial , endothelial , and stromal component of the normal breast and benign lesions , whereas an impressive loss of <n>AF</n> expression was noted in in situ and invasive breast cancer and tumoral stroma .
71847952878>Based on 213 determinations , the control mean <n>serum CPK</n> activity was 262 + / - 113 I . U . / liter .
85482913912>In vivo , selective activation of <n>SAPKs</n> stimulates formation of the ternary complex containing <n>Elk-1</n> , <n>serum response factor</n> and the <n>serum response element</n> , and enhances Elk-1-dependent transcription .
10516738347>At all time-points , most patients ( > / = 87% ) were receiving irbesartan / HCTZ alone .
7916729477>A leucine zipper domain of the <n>suppressor of Hairy-wing protein</n> mediates its repressive effect on enhancer function .
25865138024>Analysis of the inferred <n>1 , 859-residue ama-1 product</n> showed considerable identity with the largest subunit of <n>RNAP II</n> from other organisms , including the presence of a zinc finger motif near the amino terminus , and a carboxyl-terminal domain of 42 tandemly reiterated heptamers with the consensus Tyr Ser Pro Thr Ser Pro Ser .
107292204720>The two contiguous <n>IGF2</n> ( <n>human insulin-like growth factor II</n> ) and <n>H19 genes</n> are reciprocally imprinted in both human and mouse .
106849415004>The requirement of 3' complementarity for a ligation reaction is reaffirmed by results from 1 nt insertions on either the 3'- or 5'-side of the nick .
9419421858>In serum-stimulated cells , the binding of <n>NF-Y / CBF</n> to <n>TKC1</n> increased gradually , reaching a plateau at the S phase .
62249746027>Data are presented hinting that the 15 beta-hydroxy- , metabolite of CPA may actually be the biologically active agent .
7121174745>A sharp outbreak of influenza A occurred on the base during February that was due to an A / Texas / 1 / 77-like virus , a variant of the A / Victoria / 3 / 75 prototpye .
96661034792>One missense allele ( <n>P236S</n> ) with complete loss of function at 30 degreesC and four missense alleles ( <n>L173F</n> , <n>E225K</n> , <n>S269L</n> and <n>E274K</n> ) that conferred a temperature sensitive phenotype were identified .
103853841916>Similar results were obtained with xylitol , an activator of the pentose phosphate pathway .
6868366665>Pentane and ethane , which arise during lipid peroxidation in vivo , were measured by gas chromatography in breath samples of rats fed for 8 weeks a vitamin E-deficient diet to which had been added 0 , 11 , or 40 IU vitamin E acetate per kg .
63284854794>Here we have determined the nucleotide sequence of 3 . 5 kb from the 3' end of <n>delta gag</n> to the 3' end of molecularly cloned proviral MH2 DNA , in order to elucidate the genetic structure of the virus and to compare it with other <n>mht</n> - and myc-containing oncogenic viruses as well as with the <n>chicken proto-myc gene</n> .
87078467458>Concurrent with ligand-dependent uptake , we now show that the receptor undergoes ligand-induced ubiquitination , suggesting that receptor ubiquitination may function in the ligand-dependent endocytosis of the <n>a-factor receptor</n> as well as in its constitutive endocytosis .
94990613033>Cleavage and DNA joining reactions , carried out by <n>human immunodeficiency virus type 1 ( HIV-1 ) integrase</n> , are necessary to effect the covalent insertion of HIV-1 DNA into the host genome .
104288629071>Immunoprecipitation experiments using <n>DokR-specific antibodies</n> revealed an interaction between <n>endogenous DokR</n> and a 150-kDa protein that is tyrosine-phosphorylated in EGF-stimulated BaF / 3 cells .
10542260804>The requirement for proteolytic activity of both <n>FVIIa</n> and <n>FXa</n> suggests that protease-activated receptors may be involved .
117931721660>The weight-bearing surface of the PE head became smoother with time after THA , and the friction coefficient did not differ significantly from that of an unused PE head .
26369203767>Collaborative study of Japanese Pharmacopoeia Heparin Sodium Reference Standard .
86318204068>The cDNA corresponding to the <n>FPS1 gene</n> was isolated by functional complementation of a mutant yeast strain defective in <n>FPS</n> activity ( Delourme , D . , Lacroute , F . , and Karst , F .
8853303348>Pharmacokinetic parameters were similar to values given in the literature for intravenous ( IV ) or intraarterial ( IA ) bolus MMC injections ( Tmax = 7 . 0 min following the beginning of MMC infusion , Vss = 0 . 57 1 / kg , C1 = 8 . 9 ml / min . kg , T1 / 2 alpha = 8 . 3 min , T1 / 2 beta = 58 . 6 min ) .
104545618733>In the present study , we demonstrate that expression of <n>TD-IkappaBalpha</n> blocked phorbol myristate <n>acetate-phytohemagglutinin</n> or <n>tumor necrosis factor</n> alpha-induced <n>IkappaBalpha gene</n> transcription and abolished <n>NF-kappaB</n> DNA binding activity , due to the continued cytoplasmic sequestration of <n>RelA ( p65 )</n> by <n>TD-IkappaBalpha</n> .
29095281655>A second promoter activity was identified in the region between the two major transcriptional start sites .
107130831247>Unique to this system , the activity of <n>TraR</n> is negatively modulated by an antiactivator called <n>TraM</n> .
28927624893>Direct and inverted repeat elements of 10 , 11 , 16 , 19 , and 22 nucleotides ( nt ) flank the promoter site .
67603947750>Single tooth replacement with the aid of the ITI ( International Team fur Implantologie ) type F hollow-cylinder implant .
13485082136>Interestingly , the positions of these introns have been conserved in comparison with the genes of two other transglutaminase-like activities described in the literature , but the <n>TGM1 gene</n> is by far the smallest characterized to date because its introns are relatively smaller .
43236414930>Studies on swine enteroviruses .
86214534286>In addition , <n>anti-phosphotyrosine antibodies</n> immunoprecipitated <n>80K-H</n> from cell lysates of FGF-stimulated but not from control fibroblasts .
79993639095>Splice variations in genes coding for the <n>transmembrane FGF receptor</n> ( <n>FGFR</n> ) result in isoforms that vary in the ectodomain , intracellular juxtamembrane domain , and the <n>intracellular kinase domain</n> .
39819521376>The efficacy of quantitative and qualitative chloride titrators in the estimation of human salt intake .
62593896061>During the period from May to August , 1978 , an epidemic of hand , foot and mouth disease ( HFMD ) occurred in Gifu prefecture .
118001191664>The design principle based on a uniform vibration mode is presented .
18784894982>The enzymatic response of neutrophils and monocytes was similar although the magnitude of the <n>NADPH oxidase</n> activity was significantly higher in neutrophils than in monocytes .
18839923989>These results suggest that <n>beta-1</n> may act as a tissue-specific , trans-acting regulator of the expression of the <n>beta-zein gene</n> in developing maize endosperm .
115648936729>Thus , through a change in conformation upon repair of the 6RG lesion , <n>MGMT</n> switches from a DNA repair factor to a transcription regulator ( <n>R-MGMT</n> ) , enabling the cell to sense as well as respond to mutagens .
82784232615>Mothers with severe anatomical abnormalities , who are HIV positive , have active TB or whose children have inherited mono- or disaccharide intolerances should not breastfeed .
47333915127>Metal coordination compounds of thiabendazole .
8372628339>The responsiveness of visual cortex ( VC ) and superior colliculus ( SC ) was simultaneously compared following conditioning "ON" or "OFF" stimulation , in the rabbit .
31990433897>Existence and uniqueness of solutions of the appropriate boundary value problems are established , in the case of small permeability coefficients and transport rates , or large diffusion coefficients and small resistance to flow constants .
13920125650>The neurohypophysial <n>vasopressin</n> and <n>oxytocin</n> content was bioassayed by pressor effect following Dekanski or milk-ejection activity in vitro following van Dongen and Hays , respectively .
23621613021>MK-927 : a topically active ocular hypotensive <n>carbonic anhydrase</n> inhibitor .
115860961476>Because of differences in patient characteristics , control measurements were obtained from normal muscle in all patients .
104972623040>We have cloned the single-copy gene for the <n>trans -spliceosomal U5 snRNA</n> from the trypanosomatid species Leptomonas seymouri , using <n>U5 RNA</n> affinity selection and cDNA cloning .
81260962351>In these experiments we begin to study the potential functions of the <n>alpha 7 cytoplasmic domain</n> by analyzing homologies between the rat and human sequences , by immunologic studies using an anti-cytoplasmic domain antiserum , and by identifying two alternate forms .
22532747257>The Mauriceville and Varkud mitochondrial plasmids are closely related , closed-circular DNAs ( 3 . 6 and 3 . 7 kb , respectively ) that have characteristics of mtDNA introns and retroid elements .
118497965752>RESULTS : The target dose was comparable in the 3D-CRT and IMRT plans , although improvements were seen when seven and nine IMRT fields were used .
93621058287>[ Pulmonary vascular resistance ( PVR ) during 10% O2-PVR during 21% O2 / PVR during 21% O2 ] x 100 was termed as hypoxic pulmonary vasoconstriction ( HPV ) .
81886038694>This analysis revealed an intact gene ( <n>arg4</n> ) showing a high degree of homology with the <n>Saccharomyces cerevisiae CPA2 gene</n> encoding the large subunit of <n>carbamoyl-phosphate synthetase</n> ( <n>CPS-A</n> ) .
54374055543>Diminished forearm arteriolar dilator capacity produced by mineralocorticoid-induced salt retention in man .
90069147335>The effects of dominant interfering forms of the <n>JNK / p38</n> signaling pathway demonstrate that activation of these kinases is critical for cytokine-induced <n>E-selectin gene</n> expression .
29306233638>During flexion whiplash , the torque at the occipital condyle reverses its direction at about 25 ms after impact .
104908162338>Mutations of the <n>RET gene</n> , encoding a <n>receptor tyrosine kinase</n> , have been associated with the inherited cancer syndromes MEN 2A and MEN 2B .
114136411280>Analyses revealed that scale matters above and beyond the effect of quadrat area .
80559416954>The topology and chain folding of the beta subunits in the artifactual beta 60 capsid are similar to the <n>native alpha 3 beta 60 enzyme</n> .
88043899667>Northern blot analysis , using the Ltp4-specific probe , indicated that Xanthomonas campestris pv . translucens induced an increase over basal levels of <n>Ltp4 mRNA</n> , while Pseudomonas syringae pv . japonica caused a decrease .
107027945319>Together , these data identify <n>ERK2</n> as a specific and direct target of <n>HePTP</n> and are consistent with a model in which <n>HePTP</n> negatively regulates <n>ERK2</n> activity as part of a feedback mechanism .
86277198898>UV cross-linking experiments demonstrated that HSV infection caused enhanced binding of protein factors , including the <n>64-kDa component of cleavage stimulation factor</n> ( <n>CstF</n> ) , to poly ( A ) site RNAs from virus genes of all temporal classes and that this enhanced binding required expression of <n>IE63</n> .
108857506556>However , little was understood about the normal function of <n>CREB-2</n> in mammalian development or organ physiology .
25159533159>Follow-up study showed 85% of these patients with effectiveness .
107043381530>In order to gain deeper insight into the role of the amino-terminal domain of the <n>p24 ( CA )</n> protein during viral replication , eight highly conserved proline residues known to promote turns and to terminate alpha-helices within the <n>p24</n> tertiary structure were replaced by a leucine residue ( P-position-L ) .
114330148587>However , when directed to the nucleosome by fusion to <n>core histone H2A</n> or <n>H2B</n> , the non-histone tail forms an MCB that appears identical to that of the endogenous protein .
11245986521>A novel growth-related nuclear protein binds and inhibits rat <n>aldolase B gene</n> promoter .
24737187950>The investigation was apt at studying the relationship between urinary metabolites of serotonin and catecholamine ( 5-HIAA and VMA ) , T-cells ( <n>OKT3+</n> ) , T-helper ( <n>OKT4+</n> ) , T-suppressor ( <n>OKT8+</n> ) and B-cells ( EAC-rosette forming cells ) in normal ( 10 subjects , 1 female , 9 male , age 21 + / - 5 years ) and stress administered subjects ( 20 subjects , 3 female , 17 male , age 20 + / - 4 years ) .
85888528563>During the following pregnancy ultrasonographic studies of the male fetus in the 16th week of gestation revealed severe micrognathia , short and wide thumbs , and big toes , and bowed tibiae .
8073565003>Bacteriostatic and bacteriacidal activity of hydroxy-9 ellipticine in vitro .
82912338375>A cDNA clone was isolated from a chicken embryo cDNA library employing a PCR-generated radiolabeled probe specific for the <n>U3 region</n> of the Rous sarcoma virus LTR .
117087619795>Finally , there are a growing number of arguments favouring the use of <n>ACE</n> inhibitors very early in patients with diabetes mellitus .
84589068426>5 micrograms / l was detected in urine from some non-occupationally exposed persons .
77893967765>Lipiodol was covalently conjugated with EDTB .
93716986865>Transfection of HepG2 and SK-N-MC cells with constructs deleted of additional 5'-flanking fragments permitted the definition of a minimal 200 bp promoter fragment containing the pseudo-TATA box and two putative <n>SP1-binding sites</n> .
96536486743>Comparison of cDNA and genomic sequences shows that the <n>ZNF189 gene</n> spans approximately 11 kb and is organized into at least four exons , the large 3'-end exon coding for the complete zinc finger domain and the 3' untranslated region .
17307476624>86 : 3199-3203 ) or G1 to S phase ( Reilly , C .
84375216446>Mutations truncating as many as 143 C-terminal residues from the transcriptional activator encoded by the <n>areA gene</n> , mediating nitrogen metabolite repression in Aspergillus nidulans , do not significantly reduce the ability of the <n>areA product</n> to activate expression of most genes under <n>areA</n> control .
102252791368>However , we identified a gene between the <n>MDV2 UL54</n> and <n>UL55 genes</n> with homology to the first ORF ( <n>ORF-1</n> ) of equine herpesvirus type 1 and corresponding gene identified in pseudorabies virus .
92593205082>Using lectin-affinity chromatography , discordance between the pattern of O-glycosylation of <n>SSBP</n> and <n>DSBP</n> was demonstrated .
113998349544>The first case of HCV seroconversion in Portugal after the introduction of HCV NAT screening .
99175552400>Analysis of <n>hematopoietic growth factor</n> prescriptions in 19 french cancer centers .
94239686817>The mechanism underlying such analgesia has been suggested to involve the interaction between the two separate but interconnected motivational systems "defense" and "pain . " To determine the developmental course of defense and nociception , these processes were analyzed during early ontogeny in rats .
76009864996>By in vitro immunoprecipitations and gel shift assays , we identified two classes of high affinity <n>Engrailed-binding sites</n> upstream of each of the two polyhomeotic transcription units .
30093662282>From our ultrastructural and biochemical studies , it is evident that Type II pneumocytes are an early target of radiation and the release of surfactant into the alveolus shortly after exposure persists for days and weeks .
115478191426>METHODS : Experiments testing the new catheter and comparing it to the existing catheter included : ( 1 ) measurement of the laser output beam sizes and divergences ; ( 2 ) evaluation of particulate matter generation during ablation of atherosclerotic tissue ; ( 3 ) measurement of ablation hole sizes and tissue penetration rates ; ( 4 ) histopathologic examination of laser-induced in vivo vessel wall injury .
74238037277>Treatment of suppurative peritonitis .
84357558395>In Experiment 2 scopolamine hydrobromide , 0 . 5 and 1 . 0 mg / kg i . p . , was administered 1 h before each electrical stimulation until each rat showed the stage-3 seizure .
94304619648>In the clinical study , the defect size shown by BMIPP imaging was greater in anterior than in inferior infarcts ( p < 0 . 001 ) and correlated well with the risk area revealed by contrast ventriculography ( r = 0 . 80 , p < 0 . 0001 ) CONCLUSION : The above preliminary data , admittedly from a small group of patients , suggest that tomographic BMIPP imaging provides an accurate quantification of defect size by means of a simple threshold technique and , in the subacute phase , permits determination of the amount of myocardium at risk after acute myocardial infarction .
82596509671>Nucleotide sequence analysis of the <n>HA gene</n> in these two mutants confirmed the <n>HA-</n> phenotype .
78026553556>Characterization of <n>FIII / YY1</n> , a Xenopus laevis conserved zinc-finger protein binding to the first exon of <n>L1</n> and <n>L14 ribosomal protein genes</n> .
94030592362>This binary repeat contains repetitive DNA elements that include LINES , SINES , medium reiteration frequency repeats , and a transposon-like element .
112782862600>Corticosteroid-mediated transcriptional inhibition was greater for <n>MR / GR</n> in combination than for <n>MR</n> or <n>GR</n> alone .
35972694254>The other model was a continuous exponential plus constant of the form La- = a + b [ exp ( cVO2 ) ] .
81891746742>DESIGN--A randomised study was conducted in all women aged 50-70 years who were eligible for breast cancer screening and living in the city of Utrecht .
79588985681>Interestingly , <n>dTFIIA-L / S</n> is also able to significantly enhance transcriptional activation by upstream transcription factors including <n>Sp1</n> , <n>VP16</n> , and <n>NTF-1</n> .
96763493119>A "Level A" in vitro / in vivo correlation was established for a sustained release theophylline ( CAS 58-55-9 ) preparation ( Bronchoretard ) under investigation .
97706869760>The most frequent risk factor for ischaemic was hypertension .
102326007013><n>Prostate-specific antigen</n> ( <n>PSA</n> ) promoter-driven androgen-inducible expression of <n>sodium iodide symporter</n> in prostate cancer cell lines .
110759442232>In addition , <n>npm3</n> , which is usually coactivated with <n>fgf8</n> by MMTV insertion , was not up-regulated by androgens in SC-3 cells .
22811189158>Prostaglandin synthesis inhibitors have been shown to delay healing of bone and this has led to limitations on their use clinically in some situations .
114590481333>Here we show that independent of uncertainties in the models , terrestrial planets with dense atmosphere like Venus can evolve into one of only four possible rotation states .
100228674368>Elimination of <n>ETH1</n> in <n>apn1</n> strains also increased spontaneous mutation rates 9- or 31-fold compared to the wild type as determined by reversion to adenine or lysine prototrophy , respectively .
76513984084>In flies , the <n>dShc protein</n> physically associates with the activated <n>Drosophila epidermal growth factor receptor homolog</n> ( <n>DER</n> ) and is inducibly phosphorylated on tyrosine by <n>DER</n> .
88232608805>FEV1 did not fall significantly in patients without acute or chronic GVHD and recovered earlier than in patients without posttransplant pulmonary infection .
11031366863>Helicobacter pylori and stomach diseases : from clinical point of view
106886614952>Its cognate binding protein , <n>REST / NRSF</n> , is an essential transcription factor ; its null mutations result in embryonic lethality , and its dominant negative mutants produce aberrant expression of neuron-specific genes .
88375035258>These two repeat motifs are organized in an extremely well-ordered pattern in each domain , which suggests that <n>SbHRGP3</n> belongs to a new group of proteins having the repeat motifs of two distinct groups of <n>dicot extensins</n> .
108353555898>Here , we show that the <n>zinc finger protein Gis1</n> acts as a dosage-dependent suppressor of the <n>rim15Delta</n> defect in nutrient limitation-induced transcriptional derepression of <n>SSA3</n> .
78524002762><n>Rho GDP / GTP exchange inhibitor</n> , <n>Rho GDI</n> , comigrated with <n>Rac2</n> and <n>RhoA</n> , but not <n>Rac1</n> .
20358052646>Angina haemorrhagica bullosa causing respiratory obstruction postoperatively .
19065091241>In this study , we have cloned the 5'-flanking region of the <n>human nidogen gene</n> .
68076596580>Phagocytosis of tubercle bacilli by macrophages .
13164592197>Acad .
75595638493>A mutant ( residues 1-332 ) showed complete Ca2+ / CaM-dependent activity .
12943455527>A statistically significant improvement due to the administration of Bromergon was observed in symptoms associated with overreactiveness to normal <n>prolactin</n> levels , i . e . abdominal tension , edema , weight gain and breast tenderness .
76334449809>Structural organization and developmental expression pattern of the <n>mouse WD-repeat gene DMR-N9</n> immediately upstream of the <n>myotonic dystrophy locus</n> .
74057019042>Visual averaged evoked responses and <n>platelet monoamine oxidase</n> in patients suffering from alcoholism .
82343088218>Notice of retraction .
99652341829>Anisotropic heat transport in the octylcyanobiphenyl ( 8CB ) liquid crystal .
98824892359>In this study , evidence is presented that temporally and spatially specific <n>mef2</n> expression is controlled by a complex array of cis-acting regulatory modules that are responsive to different genetic signals .
118888671785>BACKGROUND : We hypothesized that the postoperative serum level of <n>TA90-IC</n> , an immune complex of a 90-kDa tumor-associated antigen and its antibody , might have a significant correlation with recurrence and survival in patients with thick primary melanomas .
53944613129>Tolerance test of HB 419 in animal experiments .
112119367370>The present data also demonstrate that ectopic expression of <n>blr1</n> increased <n>JNK / SAPK</n> activity , but <n>JNK / SAPK</n>1 activation was not needed for accelerated RA-induced differentiation and growth arrest .
111577634502>Structure of the <n>EMAPII domain</n> of <n>human aminoacyl-tRNA synthetase complex</n> reveals evolutionary dimer mimicry .
95519383113>To identify nuclear regulatory factors , we have located and functionally characterized the <n>CCR5 gene promoter</n> .
81531308126>Effects of estradiol on worm burden and peripheral leukocytes in Parastrongylus malaysiensis-infected rats .
9468509354>The protein expressed by <n>F2771 cDNA</n> in transfected COS cells is localized in the cytoplasm .
98277246012>No mutations were found in follicular adenomas .
91698531396><n>Pax-3</n> is a <n>paired-type homeobox gene</n> that is specifically expressed in the dorsal and posterior neural tube .
97178879701>The present study sought to develop an equation to estimate VO2peak in peripheral arterial occlusive disease ( PAOD ) patients with intermittent claudication and to determine independent predictors of VO2peak in this population .
87215266628>The predominant sensitizing allergens in Swedish asthmatic children are furred pet animals .
20532891465>There were 45 to 56 nt differences between the virulent and avirulent groups while there were 6 to 14 nt differences among four avirulent strains .
14216097887>These data demonstrate that DMVA does not cause more myocardial trauma than CPB when used to provide resuscitative circulatory support .
92388506619>This night-day oscillation is driven by the endogenous clock ( located in the suprachiasmatic nucleus , SCN ) .
98970329901>Magnetically induced optical self-pulsing in a nonlinear resonator .
111066682676>Furthermore , transfection of cells with the spacer-RING domain alone suppressed the antiapoptotic function of the N-terminal BIR domain of <n>c-IAP1</n> and induced apoptosis .
81798279222>Factors associated with intrafamilial transmission of hepatitis B virus infection in Korea .
104691743774>N-terminal sequence analysis and NMR measurements revealed that this fragment originates from the C-terminal 80 residues of <n>MBF1</n> and form a well structured C-terminal domain of <n>MBF1</n> , <n>MBF1CTD</n> .
78968528425>Involvement of <n>early growth response factor Egr-1</n> in <n>apolipoprotein AI gene</n> transcription .
15971706216>Eight rabbits were exposed to 0 . 7 + / - 0 . 4 mg / m3 Co2+ as CoCl2 and 1 . 2 + / - 0 . 7 mg / m3 Cr3+ as Cr ( NO3 ) 3 ( group Co + Cr ) , eight to 0 . 6 + / - 0 . 5 mg / m3 Co2+ ( group Co ) , and eight to filtered air ( control group ) , for 4 months , 5 days / week , and 6 hr / day .
38050909890>From life-table analyses of these patients , we estimated that the incidence of secondary chondrosarcoma in patients who have Ollier disease is about 25 per cent at the age of forty years , and that malignant degeneration is almost a certainty in patients who have Maffucci syndrome .
26091123274>Reagent strips are frequently used in the practice of laboratory medicine as well as outside the professional laboratories .
91080388266>Having an <n>LRR domain</n> and an <n>SH3-binding domain</n> , <n>Acan125</n> and the C . elegans homologue define a novel family of bifunctional binding proteins .
80719828057>The newly recognised skeletogenital syndrome .
10710985535>Valuing families : social work practice with families from a strengths perspective .
110739545935>The <n>Psc2 cDNA</n> contained an open reading frame homologous to <n>CP2 family proteins</n> .
84834793655>These data show that <n>PTH</n> and cAMP can repress <n>collagen promoter</n> activity in calvariae from transgenic mice , suggesting that the <n>alpha 1 ( I ) collagen promoter</n> may contain cis elements down-stream of -2 . 3 kilobases that mediate <n>PTH</n> and cAMP repression of <n>collagen gene</n> expression in bone .
9852799844>Mean <n>corpuscular hemoglobin</n> concentrations remained normal for 48 h and then decreased in both groups , the CO2 group showing the larger decrease .
109637358018>The aim of our study was to evaluate the level of oxidative stress in healthy controls ( CTL ) compared with CRF and HD patients before ( pre-HD ) and after ( post-HD ) the dialysis session , carried out on a high biocompatible polyacrylonitrile membrane AN69 .
67262579735>Effects of methiothepin and lysergic acid diethylamide on serotonin release in vitro and serotonin synthesis in vivo : possible relation to <n>serotonin autoreceptor</n> function .
40400834714>Rabbit eyes were removed and held in temperature-regulated chambers and irrigated with saline .
77205722676>In contrast to the <n>myoD promoter</n> , the <n>myoD enhancer</n> shows striking conservation between humans and mice both in its sequence and its distal position .
21881684214><n>Serum beta 2-microglobulin</n> levels ( <n>beta-2-M</n> ) were studied in 150 drug addicts , 50 of them asymptomatic carriers of <n>anti HIV-1 antibodies</n> , 50 symptomatic carriers with persistent generalized lymphadenopathy ( P . G . L . ) and 50 serum negative patients who had been living in a closed community for at least 2 years .
26044201979>During challenge , rebiopsy was done when <n>reticulin antibodies</n> turned positive ( mean 0 . 6 years , range 0 . 2-2 . 0 ) or at the end of the two year study .
25490369583>The <n>Bacillus subtilis phage phi 105 repressor</n> , a <n>lambda</n> repressor-like transcriptional regulatory <n>protein</n> , was overproduced in Escherichia coli and purified to near homogeneity in order to examine its in vitro DNA-binding properties .
5122151845>The present study examined the dependence of difference tone level [ L ( f2-f1 ) ] on the following parameters of the two-tone input : f1 , f2 / f1 ( f2 greater than f1 ) , L1 , L2 , and L1 = L2 .
84588493203>We now show that regulation of <n>flaN</n> transcription in vivo depends on a <n>sigma 54 promoter</n> and two <n>ftr elements</n> located downstream of the transcription start site at +86 ( <n>ftr2</n> ) and +120 ( <n>ftr3</n> ) .
110940752590>Subsequently , we show that the reexpression of the <n>r-PTPeta gene</n> in highly malignant rat thyroid cells transformed by retroviruses carrying the <n>v-mos</n> and <n>v-ras-Ki oncogenes</n> suppresses their malignant phenotype .
7102176897>Synovial cysts of the hip joint .
953154969>In vitro binding studies using <n>GST</n> fusion proteins and yeast extracts defined distinct binding sites on <n>yAP180A</n> for <n>Pan1p</n> and <n>clathrin</n> . <n>yAP180 proteins</n> and <n>Pan1p</n> , like <n>actin</n> , localize to peripheral patches along the plasma membrane .
105765457302>The availability of potent regulatory DNA cassettes harboring the <n>murine D1A gene promoter</n> could aid testing the neuronal-specific expression of transgenes in vivo .
74134417256>Autoradiographic localisation of its cellular distribution in the kidney .
10582831406>Syndromes of abnormal fat redistribution and metabolic complications in HIV-infected patients .
82557587166>We have identified in the 5' untranslated region of the <n>Drosophila copia retrotransposon</n> , 3' to the left LTR , a sequence for transcriptional regulation by homeoproteins .
44186874961>Effects of estrogen and glucocorticoids on the adrenal development of the fetus .
81751889392>A concentration of 12 . 5 ppm SO2 induced a decrease from baseline values of approximately 80% in mean MCA and of roughly 70% in mean CBF .
97763605179>CM reduced the nuclear binding activity of <n>transcription factor AP-1</n> .
22470728854>The <n>SUP44 suppressor mutation</n> occurs near a region of the protein that corresponds to the known positions of alterations in <n>E . coli S5 ram mutations</n> .
31192275876>The DNA sequence encodes a protein of 1520 amino acids with sequence homology to the <n>human c-abl proto-oncogene product</n> , beginning at the amino terminus and extending 656 amino acids through the region essential for <n>tyrosine kinase</n> activity .
79267396448>The expression pattern of <n>GL2</n> , as demonstrated by in situ hybridization , indicated that the gene is expressed in trichome progenitor cells and at stages associated with trichome development .
87985129953>The amount of these factors was reduced in GEO cells in which the <n>u-PAR gene</n> is only weakly transcriptionally activated .
96984578780>Homozygous mutant mice , designated <n>Cux / CDPDeltaCR1</n> , display a phenotype characterized by curly vibrissae and wavy hair .
81060875215>In the 3' flanking region of the <n>27 kDa zein gene</n> , several AATAAA-like sequences and a sequence resembling the mammalian GT-rich sequence are present around the polyadenylation sites .
13785261993>Furthermore it was suggested that FK506 plasma levels were concerned with the appearance of side effect .
11083358918>CONCLUSION : SPT is more useful than WST in differentiating patients predisposed to aspiration .
17224792300>The qualitative concentrations of <n>HCG</n> had a sensitivity of 37 . 5% and a specificity of 100% .
25216748280>Mapping of RNA- <n>temperature-sensitive mutants of Sindbis virus : complementation group F mutants</n> have lesions in <n>nsP4</n> .
95484814520>In addition to a previously characterized promoter ( <n>P1</n> ) , we now show the existence of a second promoter for the <n>human IL-5Ralpha gene</n> .
17669993906>Allergenic activity of allergen extract Ambrosia elatior ( AE ) was tested in fifteen volunteers extremely sensitive to the allergen .
24736931268>This approach was examined utilizing the fetal protein , <n>HGB F</n> .
4511925996>Data were processed with a semi-automatic computer program which develops an averaged-volume curve from an assigned LV region-of-interest .
93731409343>The <n>mouse M-lysozyme downstream enhancer</n> has been previously characterized on several levels of gene regulation .
87220115345>This complex interacts at the <n>GTPase domain</n> in the <n>large subunit rRNA</n> , overlapping the binding site of the <n>protein L11-like eukaryotic counterpart</n> ( <n>Saccharomyces cerevisiae protein L15</n> and <n>mammalian protein L12</n> ) .
64345872613>Each patient had measurable <n>LH</n> and <n>FSH</n> levels , with pulsed nocturnal secretion , and pubertal <n>LH</n> and <n>FSH</n> responses to <n>LRH</n> .
87041246423>Using one of the six fragments ( <n>CPK3-8</n> ) , we isolated a <n>2022 bp cDNA ( VrCDPK-1 )</n> from a Vigna radiata lambda gt11 library .
85325366122><n>TIEG</n> expression in hFOB cells was highly induced by <n>TGF-beta</n> and <n>bone morphogenetic protein-2</n> ( <n>BMP-2</n> ) , with a moderate induction by <n>epidermal growth factor</n> ( <n>EGF</n> ) , but no induction by other growth factors / cytokines was observed .
28434958127>Introduction of <n>v-fms</n> into a <n>CSF-1</n> dependent murine macrophage cell line induced factor independence and tumorigenicity by a nonautocrine mechanism .
64048423247>Eighteen patients were untreated , and 8 had been given previous treatment with depot testosterone 100 mg intramuscularly every 2-3 weeks for an average duration of 4 . 7 years .
16305697835>We tried amphotericin B ( AmB ) , and remission of the tumor was obtained .
4167584833>Isolation of T . gambiense strains in Zaire and their adaptation to laboratory animals .
17653756357>The mRNA identified in both human and rat cells with the <n>human clathrin</n> clone revealed transcripts of approximately 6 . 5 kb , which is consistent with the predicted 180 kDa molecular weight of the <n>clathrin heavy chain</n> .
68910516689>Survival of 111 Indium-labelled autologous platelets was studied in 2 patients after correction of platelet count and was still found shortened .
113093738922>Analysis of <n>mCTR mRNAs</n> has revealed that the three alternative promoters give rise to at least seven <n>mCTR isoforms</n> in the 5' region of the gene and generate 5'-untranslated regions of very different lengths .
7627635892>The overall incidence of SIDS was 1 . 43 per 1 , 000 live births .
91060572551>A method for the simultaneous determination of de ( N-methyl ) -N-ethyl-8 , 9 -anhydroerythromycin A 6 , 9-hemiacetal ( EM523 , I ) and its three metabolites in human plasma and urine has been developed using high-performance liquid chromatography ( HPLC ) with chemiluminescence ( CL ) detection .
762915023>Expression of the <n>CYP11A1 gene</n> is increased by hormones , such as <n>adrenocorticotropin</n> and <n>luteinizing hormone</n> , as well as by a number of <n>growth factors</n> , suggesting that its promoter may contain regulatory elements that respond to multiple signal transduction pathways .
81966073579>Deletion analysis of the <n>ICL1 promoter</n> led to the identification of an upstream activating sequence element , <n>UASICL1</n> ( <n>5' CATTCATCCG 3'</n> ) , necessary and sufficient for conferring carbon source-dependent regulation on a heterologous reporter gene .
97602439447>Cotransfections with <n>ATF-2</n> and <n>HNF-4</n> expression plasmids resulted in additive transactivation of the <n>apoCIII promoter</n> .
100132275689>Precision measurement of the pion mass difference m pi --m pi 0 .
24878983144>Once <n>NGF</n> administration is proven effective it will be possible to develop alternative ways of <n>NGF</n> administration .
23499423008>Environmental factors were more important in the older cohorts ( perhaps because of less reliable recall ) .
102290842312>Two-dimensional gel electrophoresis of <n>anti-p59fyn</n> immunoprecipitates obtained from non-transformed resting human T lymphocytes resulted in the identification of an oligomeric protein complex which is constitutively formed between <n>Fyn</n> and several additional phosphoproteins ( <n>pp43</n> , <n>pp72</n> , <n>pp85</n> , the <n>protein tyrosine kinase Pyk2</n>1 , as well as the two recently cloned adaptor proteins , <n>SKAP55</n> and <n>SLAP-130</n> ) .
79459372945>Sequence analysis of the <n>zebrafish egr1 coding region</n> revealed a high level of homology to the mouse , rat , and <n>human Egr1 genes</n> with the notable exception of a polymorphic , triplet nucleotide repeat sequence in the region coding for the amino terminus of the <n>Egr1 protein</n> .
97617119753>Pseudocontact shifts arise from the isotropic reorientational average of the dipolar coupling between unpaired electron and nuclei , in the presence of magnetic susceptibility anisotropy .
98567329847>However , no studies have been conducted to further investigate this potentially hazardous effect of lidocaine .
14295968002>On the basis of these unique properties , the newly characterized <n>hemagglutinin</n> has been termed <n>Limulus 18K agglutination-aggregation factor</n> ( <n>18K-LAF</n> ) .
62038435997>Products of immune cells such as <n>transfer factor</n> and lymphokines form the third and possibly most important group of immune-stimulating agents .
16742429956>Its clearance has been found to be decreased ( typically by around 25% , but often by far more ) by erythromycin , troleandomycin ( triacetyloleandomycin ) , roxithromycin , enoxacin , ciprofloxacin , pefloxacin , norfloxacin , ofloxacin , fluoroquinolone T-3262 , pipemidic acid , cimetidine , etintidine , propranolol , verapamil , diltiazem , nifedipine , furosemide ( frusemide ) , at least some anovulent agents , viloxazine , allopurinol , ticlopidine , idrocilamide , thiabendazole , disulfiram , influenza- and BCG-vaccination , <n>interferon</n> , and caffeine ( half-life increase ) .
26665689154>Of 110 previously untreated patients who had entered the study of protocol TCL821 , 96 were evaluable .
112156221050>Grippers with integrated piezoresistive force sensors and with attached strain gauges have been reported .
107319266785>Advanced adenoma was defined as an adenoma larger than 10 mm or an adenoma of any size with villous component , high-grade dysplasia or invasive carcinoma .
110959817280>Here , we identified three cis-elements required for replication within the 200 bp promoter , using autonomously replicating plasmids carrying various mutations and deletions .
85696843491>Oligonucleotides , designed on the basis of conserved flanking amino acid sequence segments within the catalytic domain of <n>eukaryotic protein kinase C (</n>1 <n>PKC</n>1 <n>)</n>1 <n>proteins</n>1 , were used as primers for polymerase chain reactions to amplify a 427-bp chromosomal DNA fragment from the filamentous fungus Trichoderma reesei .
87620218744>Potentially load-insensitive measures of ventricular performance were therefore evaluated in 10 open- and closed-chested , anesthetized rabbits .
82553418238>Two patients were treated successfully with a combination of metronidazole ( a tissue amoebicide ) and diloxanide ( a lumenal amoebicide ) .
21134552714>The interindividual variability of the parameters is taken into consideration by interactively determining the threshold levels .
86682092964>Merlie , Cold Spring Harbor Symp .
614785969>Late complications of catheterisation for intravenous nutrition [ letter ] .
111064283830>Toward this end , we prepared synthetic proteins with either the catalytic domain of <n>FAP-1 ( C-terminal 399 amino acids )</n> or its inactive form ( Cys2408-- > Ser ) fused to <n>glutathione-S-transferase</n> ( <n>GST</n> ) .
90069107266>To investigate the mechanisms involved in the transcriptional control of <n>retinoid X receptor</n> ( <n>RXR</n> ) gene expression , the 5'-flanking region of the <n>human RXRgamma2 isoform</n> was characterized .
84156434861>The <n>E1 gene</n> is located within the first intron of the gene for <n>RCC1</n> , a protein that regulates onset of mitosis .
18670692633>Young CD-1 mice , 4 days old , exposed to 0 . 1% nicotine sulfate on gestational days 6-20 were compared with untreated pups of the same age to determine its effect on the development of mandibular first molars .
92093724711>Here we demonstrate that <n>AML1a</n> , which solely has no effects as a transcriptional regulator , dominantly suppresses transcriptional activation by <n>AML1b</n> , and that <n>AML1a</n> exhibits the higher affinity for DNA-binding than <n>AML1b</n> .
96828979658>During the past 4 years , a purposeful search was made for electrocardiograms with documented reversible QRS changes associated with all acute injury pattern .
66293704328>Four patients ( group 1 ) had type I basement membrane nephropathy , characterized by marked thickening and lamellation of the basement membrane in a pattern resembling that of Alport's syndrome .
104971999363>A genetic screen in yeast has allowed us to identify a novel transcriptional factor binding to the <n>GlRE</n> , i . e . the <n>chicken ovalbumin upstream promoter-transcription factor II</n> ( <n>COUP-TFII</n> ) .
115609924308><n>SAPK / JNK</n> activation was completely abolished in the absence of <n>MKK7</n> , even though expression of <n>MKK4</n> was strongly upregulated in <n>mkk7 ( - / - )</n> mast cell lines , and phosphorylation of <n>MKK4</n> occurred normally in response to multiple stress stimuli .
105328058951>In a PC12 cell mutant that is deficient in <n>protein kinase A</n> activity ( AB . 11 ) , all three differentiating agents were unable to down-regulate <n>nrg-1 mRNA</n> .
17354479682>Thus , the active-site mutation prevents the wild-type processing of the N-glycosylated 73-kDa precursor of <n>PrB</n> to the <n>41 . 5 kDa pro-PrB</n> in the endoplasmic reticulum .
90590391888>99mTc-HMPAO was distributed in the territories of the ACA and MCA in the two patients who were treated with intraarterial infusion of papaverine from the C4 segment , but was distributed only to the territory of the ACA in four patients who were treated with intraarterial infusion of papaverine from the C1 segment at 1 ml / min .
39721854620>The diabetic state was characterized by mild <n>insulin</n> deficiency , plasma levels being 73% of controls , and mild hyperglycemia , with nonfasting plasma glucose levels of 1 . 5 times normal .
111677782111>Acquired <n>antithrombin</n> deficiency in sepsis .
17479722331>Thrombolytic therapy in spontaneous coronary artery dissection .
112385865861>Structural studies have shown that <n>class I major histocompatibility complex</n> ( <n>MHC</n> ) -restricted <n>peptide-specific T cell receptor ( TCR ) -alpha / betas</n> make multiple contacts with the alpha1 and alpha2 helices of the <n>MHC</n> , but it is unclear which or how many of these interactions contribute to functional binding .
57518195701>The bearing of season and sequence of calving on frequency of male , female and total calvings in Hariana cows .
71411307882>Histological evaluation revealed a more than twofold increase in the number of interepithelial mononuclear cells ( p less than 0 . 005 ) , while the number of epithelial cells / 100 microns of villous mucosa and the mean height of the epithelial cells were comparable in both groups .
109088225549>8% ( 95% CI , 21 . 3-44 . 3% ) .
104299469481>The responsive region of the <n>alpha 2 ( V ) collagen gene</n> was localized to a fragment including 100 bp of basal promoter and 150 bp of exon 1 sequences , which contained two <n>CRE-like elements</n> .
21645887450>Various <n>mutant HN genes</n> were constructed to examine the role of residues flanking the signal-anchor domain , including the cytoplasmic tail , on assembly and intracellular transport of the <n>HN glycoprotein</n> .
76391067564>A model with age and weight described the best fit for TBBMD , whereas age , weight , and height described the best fit for total body TBBMC .
20255159161>In view of the short t1 / 2 , we used three doses / day .
11502758516>These findings suggest a novel ankyrin-independent role for <n>LAD-1</n> related to <n>FGFR</n> signaling .
94202191417>To facilitate the investigation of parameters that govern selective export in adenovirus-infected cells , we constructed a marked human <n>beta-actin minigene</n> under the control of the <n>glucocorticoid-inducible enhancer-promoter</n> of mouse mammary tumor virus and introduced it into the left end of the adenovirus type 5 ( Ad5 ) genome .
61829796004>In the latter category particular emphasis is being placed on new anthracycline analogues of doxorubicin and analogues of cisplatinum diammine dichloride .
97269873193>A <n>human SPT3-TAFII31-GCN5-L acetylase complex</n> distinct from <n>transcription factor IID</n> .
9622229588>It is possible that cyclic variations in heme turnover are related to changes in erythrocyte characteristics during the progesterone phase .
86494279319>We report here the identification of a cDNA that encodes a new member of the <n>GTPase-activating protein</n> ( <n>GAP</n> ) family of <n>GTPase</n> regulators .
106291767842>In addition , <n>CaMig1</n> formed specific complexes with the <n>URS1 region</n> of the <n>S . cerevisiae FBP1 gene</n> .
6407348884>New beta-blocking drugs have been introduced which may prove beneficial in certain clinical situations since they exert more selective blockade of the <n>cardiac receptors</n> ( <n>beta1</n> ) as opposed to <n>smooth muscle receptors</n> ( <n>beta2</n> ) .
89359917669>The nucleotide sequence alignment between mouse and <n>human CA IV</n> shows 69% identity in the coding region and all of the exon-intron boundaries are conserved , as are the sizes of the introns .
27969887820>The transcription factor <n>Sp1</n> bound to eight sites , as demonstrated by footprinting assays and gel shift analysis with purified <n>Sp1</n> .
35914646845>Thus , a negative test is compatible with low disease activity and / or efficacy of calcium antagonist treatment .
104935757861>Structural changes in the C-terminus of Ca2+-bound <n>rat S100B</n> ( <n>beta beta</n> ) upon binding to a peptide derived from the C-terminal regulatory domain of <n>p53</n> .
33708154055>Rapid detection of radioisotopically contaminated test serum before radioassay of vitamin B12 .
113114641148>These disorders include low-back pain , saddle anesthesia , bilateral sciatica , then motor weakness of the lower extremities or chronic paraplegia and , bladder dysfunction .
62395456039>Weight loss reduces arterial pressure by a decrease in intravascular volume and cardiac output associated with a fall in sympathetic activity .
91498255311>A promising new cement , 4-META / MMA-TBB opaque resin , has shown remarkable adhesive properties as a bone cement in vivo .
10892300718>The first symptoms of enzootic calcinosis were noted in March 1998 , when some of the cows developed locomotor abnormalities .
29977779307>Temperature-shift experiments using synchronously grown cells of a <n>delta top1 top2</n>1 <n>temperature-sensitive</n>1 <n>(</n>1 <n>ts</n>1 <n>)</n>1 <n>double</n>1 <n>mutant</n>1 and its isogenic <n>top2</n> ts strain show that , whereas mitotic blocks can prevent killing of the <n>top2 ts mutant</n> at a nonpermissive temperature , the same treatments are ineffective in preventing cell death of the <n>delta top1 top2</n>1 <n>ts</n>1 <n>double</n>1 <n>mutant</n>1 .
95150312564>These results indicate that <n>TGF-betaf</n> potentiates the <n>c-fos SRE</n>1 activated by <n>PKC</n> through the <n>SRF binding site</n> .
86929246775>By using a DNA sequence selected for its ability to bind <n>recombinant BCL-6</n> in vitro , we show here that <n>BCL-6</n> is present in DNA-binding complexes in nuclear extracts from various B-cell lines .
13804542969>Here we demonstrate that the protein product of the <n>ref-1 gene</n> stimulates the DNA binding activity of <n>Fos-Jun heterodimers</n> , <n>Jun-Jun homodimers</n> and Hela cell <n>AP-1 proteins</n> as well as that of several other transcription factors including <n>NF-kappa B</n> , <n>Myb</n> and members of the <n>ATF / CREB family</n> .
29884576881>The data obtained up to now only suggest the future potentiality of Bestatin treatment for these types of malignancy .
21485082758>The results supported the therapeutic principle of TCM : Treating patients according to their pathophysiological patterns .
93469388294><n>Ki-ras4BVal-12</n> transfectant cells expressed 2-fold elevated protein levels of the <n>lysosomal cysteine protease cathepsin B</n> but did not up-regulate <n>cathepsin B mRNA</n> expression .
107217176616><n>Fgd3</n> and <n>FGD1</n> share a high degree of sequence identity that spans > 560 contiguous amino acid residues .
100915946976>Conformational studies combining secondary structure predictions , CD and NMR spectroscopy together with ELISA assays , showed that the greater is the propensity of the epitope for helix formation the higher is the recognition by <n>anti-K159</n> .
11030476861>Spores from Rhizopus stolonifer were suspended in distilled water ( 1 x 10 ( 6 ) spores / mL ) and used as starter .
88715671407><n>Gene 1</n> has been completely sequenced .
94784229441>BACKGROUND AND OBJECTIVES : The sexually transmitted diseases ( STD ) control program for female sex workers ( FSW ) in Lima , Peru , provided periodic serological tests for syphilis and cervical smears for gonococci , but not medication for STD or condoms .
35429454414>Ciprofloxacin : an overview of adverse experiences .
59499715836>Persistence of toxaphene in treated lakes .
10367240231>Nevertheless cryopreservation of spermatozoa in a medium containing neither SP nor biological substances could offer an acceptable cryoprotection of spermatozoa to be used in assisted fertilization procedures , especially for intracytoplasmic sperm injection .
68071496579>Comparison of three different preparations of disodium cromoglycate in the prevention of exercise-induced bronchospasm : a double-blind study .
81057273058>Fenoldopam , a <n>dopamine receptor</n> agonist , has been shown , in animal experiments , to improve renal perfusion .
77042733490>Escherichia coli JRG582 is an <n>ampD ampE</n>1 deletion derivative of strain HfrH and accordingly it is derepressed for expression of the cloned inducible <n>beta-lactamase gene</n> of Citrobacter freundii , carried on plasmid pNU305 .
5653145626>Guinea pigs weighing 300 approximately 350 g were used .
80510194665><n>Alginate</n> biosynthesis is controlled by a complex regulatory mechanism .
68844502298>In visible tumours the best results were obtained with FB ( 85% ) while TBN was positive in 65% .
103795476171>Molecules of NH3 are capable of emitting stimulated radiation ( MASER ) .
73095627177>A simplified thin-layer chromatographic determination of hippuric acid and methylhippuric acids .
83073388486>Mutations in the <n>nuclear gene CBP1 of Saccharomyces cerevisiae</n> result in degradation of <n>mitochondrially encoded cytochrome b</n> ( <n>cob</n> ) RNA ; thus , the cells are unable to respire .
1003251927>Radiative corrections to beta decay and the possibility of a fourth generation .
92221159997>Results support the hypothesis that <n>endogenous corticotropin-releasing factor</n> , perhaps acting at a peripheral binding site , suppresses the active behavioral response characteristic of pups during the early phase of isolation in novel surroundings .
83366981109><n>TFEC</n> , a <n>basic helix-loop-helix protein</n> , forms heterodimers with <n>TFE3</n> and inhibits TFE3-dependent transcription activation .
86669132787><n>Ly-49</n> is a <n>family type II transmembrane proteins</n> encoded by a gene cluster on murine chromosome 6 .
96874989743>Our results suggest that the crucial role of the mutations activating <n>v-erbA</n> as an oncogene is to 'freeze' <n>c-ErbA / TRalpha</n> in its non-liganded , repressive conformation and to facilitate its overexpression .
10499121535>All were experienced hearing aid users who wore linear Class D instruments with input compression limiting at the time of their enrollment in this study .
6513456285><n>Adenyl cyclase</n> activity of gastric mucosa in patients with duodenal ulcer before and after treatment .
11137551978>In whole sardine , domoic acid was detected in levels exceeding sometimes the regulatory limit .
31106785324>Comparison of <n>beta 2-microglobulin</n> removal using the same polysulphone membrane for haemodialysis and haemofiltration shows that <n>beta 2-microglobulin</n> is more effectively removed by convection than by diffusion when both treatment modes are matched for blood flow and urea clearance .
113139614733>The mice are phenotypically normal and do not develop spontaneous tumors at an early age , in contrast to knock-out ( <n>p53 ( - / - )</n> ) strains with a defective <n>p53 gene</n> .
117370561584>At this timepoint , many leucocytes in the ME and ET mucosa had incorporated BrdU ( between 15 and 25% within the subsets ) .
110230749344>The cost per test is less than those for CC , kEIA and PACE2 .
2169398096>Effect of succimer on the intensity of <n>tricarboxylic acid dehydrogenase</n> reactions in the brain of rats poisoned with mercuric chloride .
113140307279>Our results suggest that the C-terminal region of <n>Crk</n> contains negative regulatory elements important for both <n>Abl</n> and <n>FAK</n> dependent signal pathways , and offers a paradigm for an autoinhibitory region in the <n>SH3 linker / C-terminal SH3 domain</n> .
3696834360>Adriamycin : comparison of a 5-week schedule with a 3-week schedule in the treatment of breast cancer .
108057474295>In contrast , mutations affecting the other two <n>Nim1p-related kinases</n> in S . cerevisiae , <n>Hsl1p</n> and <n>Kcc4p</n> , produce no detectable effect on <n>septin</n> organization .
76513988444>A <n>Drosophila shc gene product</n> is implicated in signaling by the <n>DER receptor tyrosine kinase</n> .
10212426153>Group psychometric functions for listeners with hearing loss do not show a decrease in performance at the largest values of delta f included in this study .
110716517141>Thus , blocks in the RARalpha-specific pathway of retinoid-induced differentiation may be bypassed during retinoid induction of <n>FR-beta</n> expression .
20234211103>Once the proliferation of fibroblasts and <n>collagen</n> synthesis had led to an increase of mechanical strength , no negative effect on wound healing could be detected applying the same chemotherapeutic agents .
24664143124>In 10 pentobarbitalized dogs , plasma viscosity ( Ep ) was raised fourfold while apparent blood viscosity ( Ea ) increased about twofold by two steps of exchange transfusion of 200 ml of plasma with plasma containing high molecular weight dextran ( mol wt 500 , 000 , 20% wt / vol ) .
101873179850>Hospital hit for hiring AHERF physicians .
25670303221>After overtraining on the original discrimination , the controls showed the normal difficulty in learning the first reversal .
111608605736>Interestingly , the activity of <n>IkappaB kinase</n> ( <n>IKK-beta</n> ) , which plays an essential role in <n>NF-kappaB</n> activation through <n>IkappaB</n> phosphorylation , was largely enhanced in paclitaxel-treated cells , detected as <n>IkappaBalpha</n> phosphorylation .
98320992339>We evaluated regional right ventricular wall motion during systole in patients with surgically repaired tetralogy of Fallot ( TOF ) using color kinesis imaging .
97105829391>The effect of <n>Rho</n> on <n>AP-1</n> is independent of the <n>mitogen-activated protein kinase pathway</n> , as a <n>dominant-negative MEK</n> and a <n>MEK</n> inhibitor ( PD98059 ) did not affect <n>Rho-induced AP-1</n> activity .
3365471429>The mortality rate and histopathological features of Nocardia asteroides and Nocardia brasiliensis infections in congenitally athymic ( nude ) mice of ICR and C3H / eB origins were quite different from what we found for Swiss white mice and other inbred mouse strains ( namely , C57 / BL / 6J , New Zealand Black , BALB / c , CBA / LAC , and C3H / eB ) .
11086872926>Influence of oil emulsions and diphenyl on post-harvest physiconutritional changes in Kagzi limes ( Citrus aurantifolia ) was studied .
111455713903><n>IFN-stimulated gene factor-3</n> and <n>STAT1 homodimers</n> formed and bound an <n>IFN-stimulated response element</n> ( <n>ISRE</n> ) and <n>gamma-activated sequence</n> ( <n>GAS</n> ) element , respectively .
71198908094>Re : A modified method for the in vivo labeling of red blood cells with Tc-99m .
92234791997><n>ORF M1</n> has striking homology to poxvirus <n>serpins</n> , while <n>ORF M11</n> encodes a potential homolog of <n>Bcl-2-like molecules</n> encoded by other gammaherpesviruses ( <n>gene 16</n> of HVS and KSHV and the <n>BHRF1 gene</n> of EBV ) .
8072547880>A short sequence surrounding the major <n>JNK</n> phosphorylation site of <n>c-Jun</n> is conserved in <n>c-Fos</n> and is part of its activation domain , suggesting that <n>c-Fos</n> may be similarly regulated .
95105821250>Two hundred sixty-four patients scheduled for DCBM were randomized to receive intravenously geG 0 . 25 mg ( geG-25 ) , or geG 0 . 5 mg ( geG-50 ) , or HBB 20 mg as hypotonic agent .
73773787066>Estrogen replacement , either as 17 beta-estradiol or beta-estradiol-3-benzoate via subcutaneous Silastic capsules , was associated with elevated rates of heat production and dry heat loss relative to untreated ovariectomized controls .
50277995326>Sodium restriction in cardiac failure .
113198802677>Rapamycin ( <n>FRAP / mTOR</n> inhibitor ) blocked <n>4E-BP1</n> phosphorylation causing a predominance of the alpha ( hypophosphorylated ) band .
99290887324>CONTEXT : ThinPrep , AutoPap , and Papnet are 3 new technologies that increase the sensitivity and cost of cervical cancer screening .
78119646733>A unique <n>leucine-proline repeat element</n> found N-terminal to the DNA-binding domain of <n>EmBP-1</n> does not appear to play a role in DNA-binding or dimerization .
84491334103>Endosonography accurately assessed tumor extension in two T2 tumors , 14 T3 tumors , and seven T4 tumors .
96773308072>The <n>PDE4A-subfamily-specific linker region LR1</n>1 , which joins <n>UCR1</n> and <n>UCR2</n> , is encoded by two exons , whereas <n>LR2</n> , which joins <n>UCR2</n> to the catalytic unit , is encoded by a single exon .
47041865105>Range behavior of Hereford , Hereford x Holstein and Holstein non-lactating heifers .
118315126757>Forty-eight pigs were removed from sows at 1 d of age and randomly assigned to one of three treatments : 1 ) control with lactose as the carbohydrate source , 2 ) lactose replaced ( gram for gram ) with CSS ( dextrose equivalent [ DE ] -20 ) , and 3 ) lactose replaced with DE-42 .
58066155744>Oxidative degradation of adrenaline solutions : study of the intermediate stages and their analytic value for the control of this solute .
112595032781>Forskolin treatment ( 10 microM ) of the transfected cells for 3--6 h maximally induced <n>luciferase</n> threefold .
81767421262>We have used these modified assay conditions to extend studies on the transposition pathway .
91002021000>Thirty Class I and Class II recessions in 30 patients were treated with a modified subepithelial connective tissue graft procedure .
88434117908>Two classes of inactive receptors were identified : one in which both transcriptional activation and dimerization were compromised and a second in which only transcriptional activation was abolished .
87066626618>The results also imply that the absence of <n>perforin</n> expression in non-cytotoxic cells may be due to the suppression of the induction of the killer-cell-specific trans-acting factor <n>NF-P2</n> .
79445427919>Vibrio cholerae O139 in Calcutta .
25486833201>A brief account of the 1988 seminar in Shanghai on viral hepatitis A .
84193336302>To characterize the expression of this <n>DNA repair enzyme</n> , we have isolated the corresponding genomic clone .
277395101><n>Serum gamma glutamyltransferase</n> in the diagnosis of liver disease in cattle .
90577039011>Snail mortality did not differ among the various treatment conditions .
57339535684>The effect of a constant magnetic field on the phagocytic activity of Paramecia .
93680588859>However , one CAK-phosphorylated phosphopeptide comigrates with a Cdc2-phosphorylated phosphopeptide previously shown to be mitosis-specific , suggesting that , in vitro , <n>CAK</n> is able to phosphorylate at least one site that is also phosphorylated in vivo .
117731681052>The 5-year overall survival ( OS ) and progression-free survival ( PFS ) rates were 58 . 9% and 55 . 4% for arm A and 44 . 5% and 41 . 3% for arm B ( P = . 007 and P = . 02 ) , respectively .
100875498841>The JTc delta among the three groups did not differ as well : JTc delta of the VT group was 70 ms + / - 30 ms , the JTc delta of the PVC group was 60 msec + / - 25 msec , and the JTc delta of the control group was 70 ms + / - 30 ms .
34435734249>Overall least-squares means for uncooked and cooked longissimus muscle and subcutaneous fat were 63 . 32 , 80 . 27 and 98 . 90 mg of cholesterol / 100 g of tissue , respectively .
8806817797>Sequence analysis of the isolated genomic clone revealed that the DNA binding domain of this <n>orphan receptor</n> is most homologous to the <n>human TR2 receptor</n> .
7636962352>Interestingly , this amino-terminal determinant appears not to reside in the HSV-alpha <n>TIF</n> , which displays no independent amino-terminal activity .
36513304320>UVA-induced melanocytic lesions .
111372961778><n>PFK-A</n> mRNA was more abundantly expressed in all tissues than were the <n>PFK-B</n> and <n>PFK-C genes</n> .
103665599809>The hybrid viruses were found to accumulate to high levels in infected plants , to form stable virions , and to be mechanically transmissible .
10521796358>The ORs of GC , adjusted for age and sex , varied from 17 . 1 , for those with baseline diagnoses of superficial intestinal metaplasia ( IM ) , to 29 . 3 , for those with deep IM or mild dysplasia ( DYS ) or IM with glandular atrophy and neck hyperplasia , to 104 . 2 , for those with moderate or severe DYS , as compared with subjects with superficial gastritis ( SG ) or chronic atrophic gastritis ( CAG ) at baseline .
16297682223>Lesions were made by pressure injection of kainic acid into the SOC through a stereotaxically positioned glass micropipette .
82944293202>Analysis of the intact <n>hGH gene</n> or <n>hGH 5'-flanking DNA ( 5'-FR )</n> coupled to the <n>hGh cDNA</n> or <n>chloramphenicol acetyltransferase</n> or <n>luciferase genes</n> , indicated that cAMP primarily stimulated <n>hGH promoter</n> activity .
58573016195>Chemical histologic and immunologic responses in rats to CC1-4 by different routes of administration .
974953340>Clone 39 was a homolog of <n>CONSTANS</n> , which is a gene involved in controlling the flowering time in Arabidopsis .
99736079578>Here we describe the identification and characterization of several <n>Sp100 splice variant proteins</n> and support their existence by elucidation of the 3'-end of the <n>Sp100 gene</n> .
103580803955>Although linker regions in transcription factors are known to modulate DNA binding specificity , our studies suggest that the <n>human HSF1</n> linker plays no role in determining <n>HSF1</n> binding preferences in vivo but is a critical determinant in regulating the <n>HSF1 monomer-trimer</n> equilibrium .
110272747873>They also negatively modulate the <n>PI 3-kinase</n> catalytic activity but to different extents , dependent on the unique N-terminal structure of each isoform .
63190726111>We conclude that the 'morning dip' observed in asthmatic patients cannot simply be explained by changes in cell receptor number or affinity , as our results suggest that both groups have intact <n>beta-adrenoceptor</n> function .
28098311186>In contrast , the PPSF + DBP side showed large amounts of bone formation , and bone almost covered the implant .
50603885339>Clinicopathologic studies in feminizing tumors of the ovary .
68355161623>A case of a dense epidermoid cyst of the suprasellar cistern is presented .
98636245386>The divergence in primary structure between the sheep <n>CRF1</n> and the other <n>mammalian CRF1s</n> is primarily localized to the extracellular amino terminal domain of the receptor ( 18 of 22 divergent residues , ovine vs <n>human CRF1</n> ) .
91694753944>Localization of the <n>cytokine response element</n> by 5'-deletion analysis and site-directed mutagenesis revealed a cis-acting binding site for activated <n>STAT complexes</n> .
78456729725>Comparison of <n>human and murine blk sequences</n> indicated that they share 86% amino acid identity , the most conserved region being the catalytic domain ( 93% identity ) .
25733361668>An experiment on the return-of-fear ( ROF ) was carried out on 40 snake- or spider-phobic subjects in order to determine whether an arousing event that occurs shortly before retest influences the magnitude of the ROF .
87563323807>Members of the <n>Ras subfamily</n> of <n>small GTP-binding proteins</n> have been shown to be promiscuous towards a variety of putative effector molecules such as the <n>protein kinase c-Raf</n> and the <n>Ral-specific guanine nucleotide exchange factor</n> ( <n>Ral-GEF</n> ) .
88053381995>Targeted disruption of the <n>OGG1 gene</n> in yeast revealed a second <n>OG glycosylase / lyase protein</n> , tentatively named <n>Ogg2</n> , which differs from <n>Ogg1</n> in that it preferentially acts on OG : G .
98176011879>Characterization of the regulatory regions of the <n>human aromatase</n> ( <n>P450arom</n> ) gene involved in placenta-specific expression .
89948325497>Ectopic expression of <n>Apo-3</n> in HEK293 or HeLa cells induced marked apoptosis .
31428752267>Here we report the complete 6-kilobase cDNA sequence coding for a chain of 1775 amino acids , as well as the genomic structure .
111145216883>Regulation of <n>RhoA</n> is required to maintain adhesion in stationary cells , but is also critical for cell spreading and migration [ 3 ] .
11411145999>Prolonged heavy work effected an increase of 10 . 3 plus or minus 0 . 9 mmHg in in vivo P50 ( 7 . 30 PH-v , 41 degrees C-v , and 45 Pv-CO2 ) ; due entirely to the additive effects of increased venous temperature and [ H+ ] .
76936722383><n>DNase I</n> footprinting of the proximal promoter revealed four regions of protection .
96384859399>Atmospheric benzene , urinary muconic acid ( tt-MA ) and <n>leukocyte alkaline phosphatase</n> activity ( LAPA ) were evaluated among 66 car mechanics , 34 road tanker drivers , and 28 nonexposed workers .
107478906002>These results indicate that residue 266 serves as a "protein sensor" of altered minor groove interactions and identifies which base pair interactions are altered by these lesions .
40413464717>Supraventricular arrhythmias--digoxin and quinidine revisited .
103188066732>In the present study , we have investigated the functional role of the other <n>MAP kinases</n> in PDGF-mediated cellular responses .
15259662148>Differentiating among renal stones .
53561075489>Biological action and kinetics of the elimination of tritium oxide in dogs .
73127074974>Chordoma of the spinal cord in a F344 rat .
9519096095>Does afferent loop syndrome exist ? It is the author's opinion that diagnosis of the "adducent loop syndrome" is unlikely to be correct in patients subjected to Billroth-II gastrectomy .
32640733960>The active derivatives of the present series were also tested for their analgesic activity against aconitine-induced writhing in albino mice and ulcerogenic activity in albino rats .
75657763172>Disruption of the <n>HOG1</n> and <n>PBS2 genes</n> leads to a dramatic decrease of the <n>HSP12</n> inducibility in osmostressed cells , whereas overproduction of <n>Hog1</n> produces a fivefold increase in wild-type induced levels upon a shift to a high salt concentration .
92857896353><n>Human Duo</n> contains a <n>guanine nucleotide exchange factor</n> ( <n>GEF</n> ) domain that is likely to be rac1-specific , a <n>pleckstrin homology</n> ( <n>PH</n> ) domain and <n>spectrin-like repeat units</n> .
37611222148>The relations between type A behavior , clinically relevant behavior , academic achievement , and IQ in children .
31099543417>The results suggest that the greater estrogenic influence associated with the ethinyl estradiol-containing OC resulted in inhibition of coronary artery atherosclerosis despite a pronounced progestin-induced lowering of plasma HDL cholesterol concentration and , further , that hormonal balance may have a marked influence on the relationship between plasma lipids and atherogenesis .
96875142854>In this study , we describe a mammalian cell-free transcription system reconstituted with only recombinant proteins and epitope-tagged multiprotein complexes .
96093429576>We specially devised 3 types of turbo pumps , a centrifugal pump ( CFP ) , a mixed flow pump ( MFP ) , and an axial flow pump ( AFP ) , and analyzed their in vitro performance .
78517583813>Physical analysis maps <n>SAL6</n> to chromosome XVI between <n>TPK2</n> and <n>spt14</n> .
1093055746>Calcium and phosphorus metabolism in chronic uremia .
10466825859>Role of the 3' untranslated region of <n>baculovirus p10 mRNA</n> in high-level expression of foreign genes .
106447534936>The three isoforms purified with <n>anti-FLAG antibody</n> affinity column transferred sulfate to heparan sulfate and heparin but not to other glycosaminoglycans .
105215449977>Cloning and expression of a specific <n>human alpha 1 , 2-mannosidase</n> that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis .
21316522208>Higher fasting serum <n>gastrin</n> concentration ( 102 . 0 + / - 21 . 1 vs 63 . 3 + / - 8 . 3 ng . l-1 ) , and greater postprandial <n>gastrin</n> release ( AUC0-120 : 16690 + / - 2648 vs 10654 + / - 1283 ng . l-1 min ) were observed after VTP-HM than after VTP-Cas .
84465796356>Second , the <n>transcription factor Gal-ER</n> was rendered more potent and less susceptible to cell type-specific variation by fusing the strong activating domain of the <n>herpesvirus protein VP16</n> onto its C terminus .
74267457289>A progressive growth of blood erythrocyte membrane injury has been demonstrated after rats were exposed to gamma-irradiaton at a dose of 100 to 500 Gy .
86319082932><n>VDR / RXR</n> bound well to the <n>VDREs</n> and to <n>DR4</n> and <n>DR5</n> using the electrophoretic mobility shift assay .
10634007451>We describe a case of acetaminophen overdose that was treated with both hemodialysis ( HD ) and NAC due to severe intoxication and slow drug clearance .
106728999733>Acad .
93879999337>The amplitudes of DPOAE also recovered to a greater extent and outer hair cell losses were less severe in the R-PIA-treated ears .
24278699488>Furthermore , <n>beta 2-adrenoceptor</n> sensitivity appears to be unaltered in BHT .
70344791219>Fifty-eight RMI's occurred in the placebo group as compared to only twenty in the AC group ( p less than 0 . 01 ) .
119094044819>Nodal domains are regions where a function has definite sign .
11016014102>HYPOTHESIS : The aim of this study was to investigate the oxidative susceptibility of <n>apolipoprotein B-containing lipoproteins</n> and antioxidant status in patients with acute coronary syndromes and chronic stable angina pectoris .
9778197972>Cost-effectiveness analysis provides a rational means of allocating limited health care resources by allowing the comparison of the costs of lipid-lowering therapy , in particular , therapy with <n>beta-hydroxy-beta-methylglutaryl-CoA ( coenzyme A ) reductase</n> inhibitors ( statins ) , with the costs of atherosclerosis that could be prevented by lowering cholesterol .
96608234519>Further , Ser / Thr phosphorylation of downstream molecules <n>Akt</n> and <n>p70 S6 kinase</n> was inhibited .
82645795136>The cloning of <n>PTR2</n> represents the first example of the molecular genetic characterization of a eucaryotic peptide transport gene .
105755455093>These include the CACCC and CAAT motifs .
90616971558>Sixty-nine ( 44% ) patients were administered 250 MBq ( 7 mCi ) 99Tcm-tetrofosmin at rest followed 4 h later by 750 MBq ( 21 mCi ) during stress ( the 1 day protocol ) , whereas 88 ( 56% ) patients had rest and stress imaging studies on two separate days , receiving a 500 MBq ( 14 mCi ) dose of 99Tcm-tetrofosmin on each occasion ( the 2 day protocol ) .
11401849280>Liver microsomes of the shag showed smaller than 8% of the <n>epoxide hydrase</n> activity and smaller than 14% of the hydroxylating capacity of liver microsomes from the rat .
86435137364>Deletion analysis of <n>rOC promoter-chloramphenicol acetyltransferase constructs</n> demonstrates that an <n>AML-1-binding sequence</n> within the proximal promoter ( -138 to -130 nt ) contributes to 75% of the level of <n>osteocalcin gene</n> expression .
112823956326>Recently , it was shown that purified <n>RAG1 / 2 proteins</n> can cleave DNA hairpins in vitro , but the same activity was also described for a protein complex of the <n>DNA repair proteins Nbs1 / Mre11 / Rad50</n> .
76936999461>Finally , the stability of the nucleotide binding function of the two proteins is similar as assessed by sensitivity to urea .
2164604618>Our studies extend these findings and show that the <n>E2 transactivation gene</n> is expressed from multiple promoters .
110533706730>Expression of a hybrid protein containing the cytoplasmic C-terminal half of <n>UhpB</n> fused to <n>glutathione S-transferase</n> ( <n>GST</n> ) also interfered with <n>Uhp</n> signaling .
49756765284>Morphological and functional alterations noted after baboon renal allotransplantation .
84173312569>The sequence of the <n>HIR1 gene</n> predicts an 88-kDa protein with three repeats of a motif found in the <n>G beta subunit</n> of <n>retinal transducin</n> and in a yeast transcriptional repressor , <n>Tup1</n> .
22528916528>65-kilodalton protein phosphorylated by <n>interleukin 2</n> stimulation bears two putative <n>actin-binding sites</n> and two calcium-binding sites .
17094866323>The <n>murine mutation dominant white spotting</n> ( <n>W</n> ) is in the proto-oncogene , <n>c-kit</n> .
75754163948><n>Protein kinase C</n> ( <n>PKC</n> ) , a widely-distributed enzyme implicated in the regulation of many physiological processes , consists of a family of at least twelve isoenzymes which differ in tissue distribution , subcellular localization , regulatory properties , etc .
18998461080>Therefore , the <n>rbcL-rbcS locus</n> seems to be barely expressed under a standard condition for photoautotrophic growth .
105439494802>In particular , the <n>S1' specificity site</n> is a deep and highly hydrophobic cavity .
18081862413>Pigs were switched from the growing to the finishing diet at 57 and 61 kg in Exp .
78143887333>In broken L-cell membranes expressing <n>wild type or mutant M6P / IGF II receptors</n> , 30 nM <n>IGF II</n> also failed to affect the <n>pertussis toxin</n> substrate activity .
84972733360><n>NF-HB</n> ( <n>BSAP</n> ) is a repressor of the <n>murine immunoglobulin heavy-chain 3' alpha enhancer</n> at early stages of B-cell differentiation .
112383751521>We found that <n>RhoA</n> can initiate a linear kinase cascade leading to the activation of <n>ERK6</n> ( <n>p38 gamma</n> ) , a recently identified member of the <n>p38 family</n> of <n>MAPKs</n> .
114222002747><n>Granulocyte colony-stimulating factor</n> ( <n>G-CSF</n> ) administration in vivo has been shown to improve the defence mechanisms against infection by different microbes .
81801297722>Exposure to higher <n>TPA</n> concentrations decreased the content of these transcripts .
25029603152>100 and 14 p .
25864853579>GN101 , YC819-9 , and SB3 .
75927214483>Another common mutation involved amino acids that are thought to make specific contacts with DNA .
104523061213>Patients were assessed for cardiac MIBG uptake , circulating norepinephrine concentration , LVEF , peak Vo2 , x-ray cardiothoracic ratio , M-mode echographic end-diastolic diameter and right-sided heart catheterization parameters .
98842326322>Comparison of the sequences of <n>attP</n> , <n>attB</n> and bacteria-prophage junctions <n>attL</n> and <n>attR</n> showed a 26 bp common core sequence , where recombination takes place , near the 5' end of the <n>integrase gene</n> .
105889467886>This revealed a minimum of six novel <n>OSBP-related proteins</n> , designated <n>ORP-1</n> to <n>ORP-6</n> .
115954781485>Hp positive relatives of gastric cancer had a markedly higher prevalence of atrophy than those with Hp negativity without cancer relatives ( 29 vs .
94250384731>A . , Swift , A .
87103713996>We have been studying the interaction of the oncogenic human polyomavirus BK ( BKV ) with the <n>tumor-suppressor protein p53</n> to understand the biology of this virus as well as to understand the basic mechanisms of <n>p53</n> transactivation .
108619092465>The pJR vectors differ among them in : ( a ) the selectable marker ( Saccharomyces cerevisiae <n>LEU 2 gene</n> , which complements <n>S . pombe leu1- gene</n> and S . pombe <n>ura4+</n> and <n>his3+ genes</n> ) ; ( b ) the thiamine-repressible <n>nmt1 promoter</n> ( 3X , 41X and 81X with extremely high , moderate or low transcription efficiency , respectively ) ; and ( c ) the multiple cloning site ( two multiple cloning sites , with 12 restriction sites each ) .
17143221741>This report substantiates that at least two of the 18 kDa <n>hsps</n> in maize are products of different but related genes .
86184339943>The novel <n>hematopoietic growth factor FLT3 ligand</n> ( <n>FL</n> ) is the cognate ligand for the <n>FLT3</n> , <n>tyrosine kinase receptor</n> ( <n>R</n> ) , also referred to as <n>FLK-2</n> and <n>STK-1</n> .
66879532341>The mucosal defence capacity against proteolytic leukocyte enzymes .
107087699408>The <n>Mif1 5' flanking region</n> contains a functional <n>ER stress-responsive element</n> which is sufficient for induction by tunicamycin .
30501473587>After infection of 293 cells ( which provide complementary <n>E1a-E1b</n> functions ) , both viruses directed equal amounts of <n>P / C-specific mRNA</n> transcription .
84594656840>This prospective study compared the measured energy expenditures of 30 patients using indirect calorimetry with their predicted basal energy expenditure according to the Harris-Benedict equation , or their calculated energy expenditure derived from basal energy expenditure times , an activity factor , and a stress factor .
104390404970>To determine what role <n>eIF4E</n> might play in <n>c-myc</n> expression , the <n>c-myc 5' untranslated region ( UTR )</n> was fused in-frame to <n>CAT reporters</n> , and several more derivative constructs were made .
33667204052>Such a change may involve increased mammary utilization of pre-formed long-chain fatty acid and increased metabolism of glucose via glycolysis .
87127998695>Unaided attempts to quit smoking are generally unsuccessful .
53408015480><n>Mycotoxins</n> in feeds and foods .
13964442012>The experiments show that it is the micromilieu of the alveoli and the condition of the AM ( certain physiological activation states , such as phagocytic activity ) that essentially determine the degree of recovery .
40889366942>Comparative studies of the <n>antithrombin III</n> level and <n>plasminogen activator</n> activity in patients with thrombophlebitis .
80358334639>Thus , <n>YMIP</n> is a functional homolog of <n>RMIP</n> and represents a new component of the yeast mitochondrial import machinery .
83043018278>METHODS : Forty-nine cases with intrahepatic multiple nodules of HCC , by gross examination , among 184 consecutive resected HCCs were examined clinicopathologically .
52763805450>Influence of cigarette smoking on some blood coagulation tests .
24881482853>During the program's use at the RSNA meeting , the program selected the correct diagnosis in the top five 22% of the time .
9259315105>Mutation of <n>Enh4</n> , an essential <n>GT-IIC-like enhanson</n> in the context of the intact enhancer , abolishes silencer activity , and multimerized <n>GT-IIC enhansons</n> mimic the intact <n>CSEn enhancer / silencer</n> activities in BeWo and GC cells , respectively .
80111662696>The complete gene organization was obtained by combining the results of the sequence of these clones and those of the characterization of <n>polymerase</n> chain reaction-amplified genomic segments .
9843378688>The <n>dopamine D4 receptor</n> as well as many other <n>catecholaminergic receptors</n> contain several putative <n>SH3 binding domains</n> .
82995684784>These data indicate that activation of these enzymes is not sufficient for the acute stimulation of glucose transport .
115129251633>EXAFS measurements around the Ge-K edge have been carried out for liquid Ge-Si alloys for the first time to investigate the local structure around a Ge atom .
11137367976>We used the Toshiba IIDR system , which is composed of an X-ray TV system and a digital image managing circuit .
118261411697>Dissociable effects of lidocaine inactivation of the rostral and caudal basolateral amygdala on the maintenance and reinstatement of cocaine-seeking behavior in rats .
29362843643>Spontaneous degradation of atracurium in plasma is the major route of elimination in man and contributes to a short elimination half-life ( approximatively 20 min ) .
97739756198><n>Wild-type AT1A receptors</n> , expressed in Chinese hamster ovary cells , rapidly internalized after <n>Ang II</n> stimulation [ t1 / 2 2 . 3 min ; maximal level of internalization ( Ymax ) 78 . 2% ] , as did mutant receptors carrying single acidic substitutions ( T332E , t1 / 2 2 . 7 min , Ymax 76 . 3% ; S335D , t1 / 2 2 . 4 min , Ymax 76 . 7% ; T336E , t1 / 2 2 . 5 min , Ymax 78 . 2% ; S338D , t1 / 2 2 . 6 min , Ymax 78 . 4% ) .
88173238214>Almost complete sequence identity was found between the 3' end of the <n>DXS6673E gene</n> and two expressed sequence tags ( ESTs ) and between the 5' end of the <n>DXS6673E gene</n> and a third EST .
51613995405>1 .
107866711598>The rate-limiting step for <n>telomerase</n> activity seems to be the expression of the catalytic subunit of the enzyme , encoded by the <n>human telomerase reverse transcriptase</n> ( <n>hTERT</n> ) gene .
10691972411>Characterization of the 5'-flanking region of the <n>human multidrug resistance protein 2</n> ( <n>MRP2</n> ) gene and its regulation in comparison withthe <n>multidrug resistance protein 3</n> ( <n>MRP3</n> ) gene .
105593037643><n>Epstein-Barr virus ( EBV ) latent membrane protein 1</n> ( <n>LMP1</n> ) is essential for EBV-mediated transformation of primary B lymphocytes .
80637759804>Regulation of <n>parathyroid hormone-related protein</n> ( <n>PTHrP</n> ) gene expression .
94261433262>Taken together , our data suggest that the antagonistic effects of <n>CRP</n> and <n>KdgR</n> on the expression of the <n>pectinolysis genes</n> occur by different mechanisms , including direct competition between the two regulators or between the repressor and <n>RNA polymerase</n> for the occupation of a common DNA region on the target genes .
95373757516>In a <n>gntR deletion mutant</n> , the expression of a <n>chromosomal gntT : : lacZ fusion</n> is both high and constitutive , confirming that <n>GntR</n> is the negative regulator of <n>gntT</n> .
76361879429>Consistent with the protein expression data , <n>V beta 8 . 3 gene transcripts</n> were found only in the transgenic lines with the wild-type promoter .
106024199752>These synergistic effects were strongly <n>Jem-1</n> dose-dependent .
10220364160>Their afterglows are brighter than supernovae and therefore are called hypernovae .
107878042428>AMDA white paper identifies ways to improve pharmaceutical care in SNFs .
60655075886>Compensatory renal hypertrophy in parabiotic rats .
59387205829>Story of a hospital that filmed its employee orientation program .
104775999688>An activation-responsive element in <n>single C motif-1 / lymphotactin promoter</n> is a site of constitutive and inducible DNA-protein interactions involving nuclear factor of activated T cell .
86172384068>TNF Treatment of cell activated the <n>p38 MAP kinase</n> pathway , as revealed by increased phosphorylation of <n>p38 MAP kinase</n> itself , activation of the substrate protein <n>MAPKAP kinase-2</n> , and culminating in the phosphorylation of the <n>heat shock protein 27</n> ( <n>hsp27</n> ) .
4658295081>Nernst--Planck analog equations and stationary state membrane electric potentials .
2442837541>Two of the three groups were administered dauricine , as a new calcium channel blocker , and verapamil , as a generally recognized calcium channel blocker , respectively , from 15 minutes pre-bypass to the end of the bypass procedure ( a period of 95 minutes ) .
5830046921>Contrary to 1 , 8-dihydroxy-9-anthrone , 1 , 8 , 9-triacetoxyanthracene and 1 , 8-diacetoxy-9-anthrone are effective against psoriatic lesions without accompanying inflammations of the skin .
21474228986>We have isolated and sequenced the gene encoding the <n>human U1-70K snRNP protein</n> .
93137559280>Underlying the clustering of these risk variables were three factors .
14871445955>We found that the gene segment containing the <n>mu m poly ( A ) signals</n> , along with 536 bp of downstream flanking sequence , acted as a transcription terminator in both myeloma cells and L cell fibroblasts .
100825731889>These results continue to support the hypothesis that <n>HS2</n> , <n>HS3</n> , and <n>HS4</n> act as a single , integral unit to regulate <n>human globin gene</n> transcription as a holocomplex , but they can also be interpreted to say that formation of a <n>DNase I</n> hypersensitive holocomplex alone is not sufficient for mediating high-level <n>globin gene</n> transcription .
102320788885>Ischemia and reperfusion markedly increased the release of <n>6-keto-PGF1 alpha</n> and <n>TXB2</n> .
28746353560>Prenatal exposure to the fungicide dinocap causes behavioral torticollis , ballooning and cleft palate in mice , but not rats or hamsters .
54513248528>Calibration and a correction of blood O2 content measured by Po2 and