Table 1: Abbreviations and technical terms

Abbreviations
3D three-dimensional (co-ordinates of protein structure)
2D 2D two-dimensional (e.g. inter-residue contacts)
1D 1D one-dimensional (e.g. sequence or string of secondary structure)
db database
ORF open reading frame
U protein sequence of unknown 3D structure and/or unknown function (e.g. search sequence in alignment procedure)
T target used for homology modelling (protein of known 3D structure)

Terms
sequence identity percentage of residues identical (D->E = 0; D->D = 1) between two sequences aligned (insertions excluded)
sequence similarity percentage of residues similar (D->E = 1; D->D = 1) between two sequences aligned (insertions excluded); there are two ways to convert similarity into percentage values: (i) by normalising the similarity score by the maximal possible score (percentage residue similarity), and (ii) by setting an arbitrary threshold of the similarity score to distinguish similar-not similar and counting the percentage of residues that are similar according to this threshold (percentage of similar residues); note that different similarity metrices are used to account for physico-chemical properties of amino acids, consequently, levels of similarity are usually not directly comparable between different alignment methods) miscellaneous

Computer
browser program used to access the WWW
CPU Central Processing Unit, i.e., 'core' of the computer
ftp file transfer protocol, i.e., program to copy files via the internet
HTML HyperText Markup Language, i.e., format of a WWW document
Internet most important network connecting computers worldwide
plug-in module to be plugged into your WWW browser, provides special functionality, such as graphics to display 3D structures
URL Uniform Resource Locator, i.e., address of a WWW site (in other words the address you have to provide to open a location)
WWW (W3, Web) World Wide Web, i.e., vehicle for accessing and offering documents via the Internet




EMBL Home Sander Home Rost Home Mail to Rost Schneider Home