Transmembrane helices for mycge (Mycoplasma genitalium)

Jinfeng Liu & Burkhard Rost

CUBIC Columbia Univ, Dept Biochem & Mol Biophysics

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Description of Mycoplasma genitalium

taxonomy: Bacteria; Firmicutes; Bacillus/Clostridium group; Mollicutes; Mycoplasmataceae; Mycoplasma
Mycoplasmas are members of the class Mollicutes and comprise a large group of bacteria which lack a cell wall, have small genomes, and a characteristically low G+ C content. These diverse organisms are parasites for a wide range of hosts including humans, animals, insects, plants, and cells grown in tissue culture. Aside from their role as pathogens, mycoplasmas are of interest because they are believed to represent a minimal life form, having yielded to selective pressure to reduce genome size. The species with the smallest genome size in this class is Mycoplasma genitalium (580 kb), which was originally isolated from urethral specimens of patients with non-gonoccocal urethritis and has since been shown to exist in parasitic association with ciliated epithelial cells of primate genital and respiratory tracts .
The total number of ORF of Mycoplasma genitalium used in this study is 470.

	Number of proteins			Percentage of proteins in entire genome			Cumulative percentage of proteins in entire genome
Nhtm	all	top=in	top=out	all	top=in	top=out	all	top=in	top=out
1	20	9	11	4.3	1.9	2.3	19.8	10.6	9.1
2	15	9	6	3.2	1.9	1.3	15.5	8.7	6.8
3	7	3	4	1.5	0.6	0.9	12.3	6.8	5.5
4	5	4	1	1.1	0.9	0.2	10.9	6.2	4.7
5	5	1	4	1.1	0.2	0.9	9.8	5.3	4.5
6	9	8	1	1.9	1.7	0.2	8.7	5.1	3.6
7	12	4	8	2.6	0.9	1.7	6.8	3.4	3.4
8	7	3	4	1.5	0.6	0.9	4.3	2.6	1.7
9	3	1	2	0.6	0.2	0.4	2.8	1.9	0.9
10	3	3	0	0.6	0.6	0.0	2.1	1.7	0.4
11	2	1	1	0.4	0.2	0.2	1.5	1.1	0.4
12	4	3	1	0.9	0.6	0.2	1.1	0.9	0.2
13	1	1	0	0.2	0.2	0.0	0.2	0.2	0.0

nHTM HTML ASCII

at least 10 HTMs HTML ASCII

7--9 HTMs HTML ASCII

4--6 HTMs HTML ASCII

3 HTMs HTML ASCII

2 HTMs HTML ASCII

1 HTM HTML ASCII

Last update: Nov 30, 1999 Contact CUBIC WWW administrator:
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